Anatomy, Physiology, Sports and Excercise Science, and Nutrition MRes/PhD Supervisors
Sports and Excercise Science
- Nick Blockley (Advanced magnetic resonance imaging methods to non invasively measure challenging aspects of human physiology, particularly oxygen metabolism, vascular reactivity and blood volume). My research focuses on developing advanced magnetic resonance imaging (MRI) methods to measure human brain physiology non invasively. I concentrate on imaging aspects of brain function that are otherwise difficult to capture, particularly oxygen metabolism, cerebrovascular reactivity and cerebral blood volume.
- Paul Greenhaff (Ageing, Exercise, Energy and Fuel Metabolism, Fatigue, Muscle Atrophy, Physiology, Inactivity, Recovery and Rehabilitation, Integrative Physiology). Paul Greenhaff is Professor of Muscle Metabolism at the 糖心原创, where he has helped build and establish state-of-the-art facilities for human integrative physiology, metabolism and nutrition research over the past 3 decades. This has included the development of know-how to perform controlled physiological and metabolic studies at rest and during exercise in human volunteers, and most recently within the bore of a whole-body MRI magnet (so called physiological imaging).
- Tasuku Terada (clinical exercise physiology, obesity, type 2 diabetes, cardiovascular disease, exercise intervention). My research encompasses broad areas within applied exercise physiology, with a specific focus on clinical exercise physiology. My research focuses on developing feasible, evidence-based exercise interventions tailored to diverse populations, such as type 2 diabetes, cardiovascular disease, and older women, to enhance functional fitness and cardiometabolic and cardiovascular health.
- Will Tyne (Qualitative, Quantitative, Mixed Methods, Wellbeing, Occupational Psychology, Sport, Exercise, Physical Activity, Health). William Tyne is a Chartered Psychologist with the British Psychological Society and a Fellow of the Higher Education Academy. William joined the 糖心原创 as a Teaching Fellow on the BSc Sport and Exercise Science course within the School of Life Sciences, following the completion of his PhD at Loughborough University in 2023.
- Laurence Warren Westgate (Perceptual- cognitive psychology; exercise behaviour)
Human Anatomy and Cell Biology Supervisors
- Susan Anderson My area of research is bone biology and bone biomaterials. I am currently working on the mechanisms controlling bone growth and their involvement in the pathogenesis of Adolescent Idiopathic Scoliosis (AIS), with a specific interest in leptin and the endocannabinoid system. I also work on establishing the role of silicon and silicates in bone growth and their incorporation into novel biomaterials.
- Nick Blockley (Advanced magnetic resonance imaging methods to non invasively measure challenging aspects of human physiology, particularly oxygen metabolism, vascular reactivity and blood volume). My research focuses on developing advanced magnetic resonance imaging (MRI) methods to measure human brain physiology non invasively. I concentrate on imaging aspects of brain function that are otherwise difficult to capture, particularly oxygen metabolism, cerebrovascular reactivity and cerebral blood volume.
- Martin Gering (How blood cells form during vertebrate embryogenesis; haematopoietic stem cells (HSCs))
- Lopa Leach (Regulation of vascular flow and barrier function in the human placenta in normal and compromised pregnancies)
- Vera Ralevic (Endothelium; purines (P1 and P2 receptors); cannabinoids; vanilloids)
- Sebastian Serres (metabolism, brain, imaging, astrocyte, tracer).
- Paul Smith (Patch-clamp, electrophysiology, pharmacology, ion channels, physiology, electrochemistry, sympathetic, white fat adipocytes, pancreatic beta-cell). I’m fascinated by how cells work: how their behaviour is shaped by the electrical language of ion channels. My primary focus is the membrane membrane physiology of white adipocytes, especially during the hyperplasia and hypertrophy that accompany weight gain and obesity. I am also interested in how their extracellular matrix controls the ion flux and membrane potential of this cell type. I am also exploring how lipophilic molecules—ranging from therapeutic drugs to persistent “forever chemicals”—are stored, mobilized, and ultimately influence adipocyte function.
Metabolic Nutrition and Physiology Supervisors
- Susan Anderson My area of research is bone biology and bone biomaterials. I am currently working on the mechanisms controlling bone growth and their involvement in the pathogenesis of Adolescent Idiopathic Scoliosis (AIS), with a specific interest in leptin and the endocannabinoid system. I also work on establishing the role of silicon and silicates in bone growth and their incorporation into novel biomaterials.
- Nick Blockley (Advanced magnetic resonance imaging methods to non invasively measure challenging aspects of human physiology, particularly oxygen metabolism, vascular reactivity and blood volume). My research focuses on developing advanced magnetic resonance imaging (MRI) methods to measure human brain physiology non invasively. I concentrate on imaging aspects of brain function that are otherwise difficult to capture, particularly oxygen metabolism, cerebrovascular reactivity and cerebral blood volume.
- Matthew Brook (Skeletal muscle mass regulation, Stable isotope tracers in metabolic Research)
- Mark Cole (Hypoxia and diet)
- Paul Greenhaff (Ageing, Exercise, Energy and Fuel Metabolism, Fatigue, Muscle Atrophy, Physiology, Inactivity, Recovery and Rehabilitation, Integrative Physiology). Paul Greenhaff is Professor of Muscle Metabolism at the 糖心原创, where he has helped build and establish state-of-the-art facilities for human integrative physiology, metabolism and nutrition research over the past 3 decades. This has included the development of know-how to perform controlled physiological and metabolic studies at rest and during exercise in human volunteers, and most recently within the bore of a whole-body MRI magnet (so called physiological imaging).
- Liz Simpson (Diabetes, Metabolism, Gut Hormones, and Body Composition)
- Moira Taylor (Obesity; Disease related undernutrition; Phytochemicals)
- Tasuku Terada (clinical exercise physiology, obesity, type 2 diabetes, cardiovascular disease, exercise intervention). My research encompasses broad areas within applied exercise physiology, with a specific focus on clinical exercise physiology. My research focuses on developing feasible, evidence-based exercise interventions tailored to diverse populations, such as type 2 diabetes, cardiovascular disease, and older women, to enhance functional fitness and cardiometabolic and cardiovascular health.
- Kostas Tsintzas (Obesity, diabetes and ageing; Skeletal muscle, liver and adipose tissue; Nutrition and exercise in health and disease)
Physiology and Pharmacology Supervisors
- Nicholas Blockley (Imaging human physiology using magnetic resonance imaging (MRI))
- Mark Cole (Hypoxia and diet)
- Paul Greenhaff (Skeletal muscle mass regulation and muscle fuel metabolism)
- Martin Gering (How blood cells form during vertebrate embryogenesis; haematopoietic stem cells (HSCs))
- Siobhan Loughna (CHD, congenital heart disease, heart defects, Prkd1, Cdk13, pathogenic variants, humanised transgenic mutant mouse, high resolution episcopic microscopy). Our research interests are to provide insights into how the heart forms during early stages of cardiogenesis, and how it goes wrong leading to defects. Congenital heart disease is relatively common (approximately 0.8% of newborn babies), with most cases having an unknown cause. In collaboration with Professor David Brook, we have analysed a number of mouse lines which carry deletions or humanised mutations for genes which are know to cause heart defects in humans. Our current genes of interest are Cdk13 and Prkd1, with both encoding a protein kinase. Mutations in these genes result in congenital heart disease. Morphological analysis is by high resolution episcopic microscopy (HREM), which allows 2D and 3D analysis of the hearts. A range of developmental, cell and molecular biology techniques are employed in the laboratory to decipher the expression of these genes of interest and understand the abnormalities seen. Further, functional studies are performed to provide insights into what role the genes play in the heart in order to explain how defects form.
- Vera Ralevic (Endothelium; purines (P1 and P2 receptors); cannabinoids; vanilloids)
- Richard Roberts (Cardiovascular pharmacology including the study of signal transduction pathways that mediate vasoconstriction)
- Sebastian Serres (metabolism, brain, imaging, astrocyte, tracer).
- Paul Smith (Patch-clamp, electrophysiology, pharmacology, ion channels, physiology, electrochemistry, sympathetic, white fat adipocytes, pancreatic beta-cell). I’m fascinated by how cells work: how their behaviour is shaped by the electrical language of ion channels. My primary focus is the membrane membrane physiology of white adipocytes, especially during the hyperplasia and hypertrophy that accompany weight gain and obesity. I am also interested in how their extracellular matrix controls the ion flux and membrane potential of this cell type. I am also exploring how lipophilic molecules—ranging from therapeutic drugs to persistent “forever chemicals”—are stored, mobilized, and ultimately influence adipocyte function.
- Kostas Tsintzas (Obesity, diabetes and ageing; Skeletal muscle, liver and adipose tissue; Nutrition and exercise in health and disease)