糖心原创

School of Life Sciences

Infections and Immunity Supervisors

Immunology Supervisors
  • Lucy Fairclough (Immunology, Allergy, Smoking, Vaping, Inflaflamtion, Extracellular Vesicles, Epithelial Cells, Immune Cells) 
  • Amir Ghaemmaghami (Immune instructive materials).
  • Ruth Griffin (Mucosal vaccines, platform delivery technologies, infectious diseases, bacterial pathogens, antimicrobial peptides).
  • Kim Hardie (Biofilm, Pseudomonas aeruginosa, protein secretion, AMR, Staphylococcus aureus)
  • Barnabas King (Determining and characterising mutations in virus surface proteins that influence entry and antibody recognition). My current research interests focus on the identification and characterisation of genetic diversity in pathogenic human viruses. Recent work in the lab has looked at: Genetic diversity and seasonal fluctuations in respiratory syncytial virus (RSV). Developing pseudotyped virus assays for mammalian alpha coronaviruses,The challenges, inequalities and solutions in preventing mother to child transmission (MTCT) of hepatitis B virus (HBV) is under resources healthcare settings,Understanding viral factors involved in MTCT in HBV,Generating infectious clones of genotype 3 hepatitis C virus (HCV) isolated from patients,Describing hepacivirus transmission and infections in horses.
  • Patrick McClure (emerging infectious diseases; respiratory viruses; viral epidemiology; virus discovery; viral diagnostics; whole genome sequencing; unbiased sequencing).
  • Luisa Martinez-Pomares (Inflammation, lectin receptors, macrophages, infection, cellular biology, biochemistry).
  • Neil Oldfield (molecular microbiology, bacterial pathogenesis, vaccines, Neisseria meningitidis, Neisseria gonorrhoeae).
  • Marie Pardon (Pathways involved in the progression of Alzheimer's; The stress hormone corticosterone; Modelling post-partum depression; Understanding how prenatal stress influences brain development and aging).
  • Patrick Tighe (Immunology, automation, high-throughput).
  • Uwe Vinkemeier (Signal transduction in myeloid cells).
  • Klaus Winzer (Bacteria, Metabolism, Physiology, Biochemistry, Fermentation, Metabolic Engineering, Biological Engineering).
 
Virology Supervisors
      • Christopher Coleman (Coronavirus: host interactions)
      • Barnabas King (Determining and characterising mutations in virus surface proteins that influence entry and antibody recognition). My current research interests focus on the identification and characterisation of genetic diversity in pathogenic human viruses. Recent work in the lab has looked at: Genetic diversity and seasonal fluctuations in respiratory syncytial virus (RSV). Developing pseudotyped virus assays for mammalian alpha coronaviruses,The challenges, inequalities and solutions in preventing mother to child transmission (MTCT) of hepatitis B virus (HBV) is under resources healthcare settings,Understanding viral factors involved in MTCT in HBV,Generating infectious clones of genotype 3 hepatitis C virus (HCV) isolated from patients,Describing hepacivirus transmission and infections in horses.
      • Patrick McClure (emerging infectious diseases; respiratory viruses; viral epidemiology; virus discovery; viral diagnostics; whole genome sequencing; unbiased sequencing).
      • Alexander Tarr (Hepatitis C virus)
 
Parasitology Supervisors
  • Andrew MacColl (Fish parasitology).
  • Catarina Gadelha Understanding and disrupting the cellular and molecular interactions between the human host and protozoan parasites.
  • Chris Wade (Snails as intermediate hosts for medically important parasites).
  • Bill Wickstead (Genomic, molecular and bioinformatic methods to understand the fundamental biology of microbial parasites). The Wickstead lab conducts research to understand the biology of parasites and the evolution of complex cells. This includes work on cell division, evasion of the immune system, and gene family evolution. Our research often integrates genomics and molecular biology with bioinformatic and computational tools. Much of the work in the lab involves the parasite Trypanosoma brucei, which causes a fatal disease known as "sleeping sickness" in humans. 
 
Microbiology Supervisors
  • Steve Atkinson (Clinical and cellular microbiology of medically important bacteria - Yersinia species).
  • Ed Bolt (CRISPR Biology & Biotechnology, DNA repair,  Homologous Recombination).
  • Matthias Brock (Fungi, Metabolism, Fungal Infections, Therapy, neutral Products, Biotechnology, Synthetic Biology).
  • Christopher Coleman (Biology of coronaviruses).
  • Paul Dyer (Fungal Biology, Food Mycology, Genetics, Genomics, Mould-ripened Cheese).
  • Ruth Griffin (Mucosal vaccines, platform delivery technologies, infectious diseases, bacterial pathogens, antimicrobial peptides).
  • Kim Hardie (Biofilm, Pseudomonas aeruginosa, protein secretion, AMR, Staphylococcus aureus)
  • Yan Liao My research focuses on understanding the molecular mechanisms that archaeal cells use for adaptation, interaction, and division, and on developing these systems for novel biotechnological applications relevant to environmental and human health.
  • Naomi Martin (cancer immunology, immune evasion, flow cytometry, immune dysfunction, endothelial dysfunction, extracellular vesicles). Recently, I have been working on projects investigating mechanisms of cancer immune evasion and the effects of stressed and metastatic cancer cells on the phenotype of neighbouring healthy cells in in vitro co-cultures.My research also investigates the function of extracellular vesicles in disease processes such as cancer and cardiovascular disease and their role in the susceptibility of certain ethnic groups to these diseases. I investigate how these novel markers of immune function and inflammation are altered phenotypically and their effects on disease pathophysiology and cellular dysfunction. I also have an interest in the effects of polluting microplastics on cancer progression and pathophysiologyand cellular dysfunction. 
  • Luisa Martinez-Pomares (Inflammation, lectin receptors, macrophages, infection, cellular biology, biochemistry).
  • Neil Oldfield (molecular microbiology, bacterial pathogenesis, vaccines, Neisseria meningitidis, Neisseria gonorrhoeae).
  • Stephan Heeb (Clinical and cellular microbiology of medically important bacteria - Pseudomonas aeruginosa and Staphylococcus aureus)
  • Rita Tewari (Malaria biology).
  • David Turner (Clinical Microbiology). 
  • Karl Wooldridge (Clinical and cellular microbiology of medically important bacteria - Neisseria species)
 

 

 

School of Life Sciences

糖心原创
Medical School
Queen's Medical Centre
Nottingham NG7 2UH

e: life-sciences@nottingham.ac.uk
t: +44 (0)115 823 0141
f: +44 (0)115 823 0142