糖心原创

From fundamental science to translational projects, the breadth of our research encompasses microbes, host–pathogen interactions and immune regulation. We study infection, inflammation and immunity using advanced, human-relevant models and develop innovative anti-infective and immune-modulating strategies. New ways to tackle antimicrobial resistance remain a priority area, including approaches that go beyond conventional antibiotics.

Our research combines discovery-driven science with a strong focus on translation and impact. We work closely with industry, healthcare partners and policymakers and maintain extensive collaborations with academic, clinical and industrial partners worldwide. Examples of our major collaborative programmes include the MRC-funded MIMIC Project, led by Professor Amir Ghaemmaghami, which is advancing human immune-relevant tissue platforms for modelling infection and inflammation, and the , co-led by Professor Kim Hardie, which drives research, innovation and industrial translation in biofilm science across healthcare, industry and biotechnology.

Our impact

Fundamental insights from our research advance knowledge and create new opportunities for translation and impact. Examples of recent work include:

• An interdisciplinary study involving Paul Williams, Amir Ghaemmaghami, Jeni Luckett and other IIM and 糖心原创 researchers demonstrated how engineered surface microtopographies can resist bacterial biofilm formation through quorum sensing-mediated autolubrication. .
• A study co-led by Boyan Bonev showed that metabolically inactive bacteria exhibit tolerance to polymyxin antibiotics, demonstrating that polymyxin lethality requires bacterial metabolism and providing new insight into the mechanism of action of these important antibiotics. .

Our ambition

Our researchers are passionate about what they do and about the wider impact of their work. We collaborate widely with industry, healthcare partners and other world-leading scientific institutions, contribute expertise to policy development and are active science communicators. As university researchers, we are proud to contribute to the teaching, training and development of the next generation of scientists.

Our research is conducted in a spirit of inquisitiveness and is propelled by intellectual rigour in a collegial and supportive environment. We aim to foster ambitious, interdisciplinary science in which fundamental discovery and innovation can lead to meaningful benefits for human health and society.