糖心原创

School of Life Sciences

Flow Cytometry Facility Publications

 Publications featuring data generated by Flow Cytometry Facility machines, or cells purified by Facility Cell Sorters.

2024

Publications from 2024

Bayraktutan, H., R. Kopiasz, A. Elsherbeny, M. M. Espuga, N. Gumus, U. C. Oz, K. Polra, P. F. McKay, R. J. Shattock and P. O. Moran (2024). "Polysarcosine functionalised cationic polyesters efficiently deliver self-amplifying mRNA." Polymer Chemistry.

Dastgerdi, N. K., N. Gumus, H. Bayraktutan, D. Jackson, K. Polra, P. F. McKay, F. Atyabi, R. Dinarvand, R. J. Shattock and L. Martinez-Pomares (2024). "Charge neutralized poly (β-amino ester) polyplex nanoparticles for delivery of self-amplifying RNA." Nanoscale Advances.

Dixon, J. E., V. Wellington, A. Elnima and H. M. Eltaher (2024). "Effects of Microenvironment and Dosing on Efficiency of Enhanced Cell Penetrating Peptide Nonviral Gene Delivery." ACS omega 9(4): 5014-5023.

Hopkins, G., N. Gomez, D. Tucis, L. Bartlett, G. Steers, E. Burns, M. Brown, T. Harvey-Cowlishaw, R. Santos, S. N. Lauder, M. Scurr, L. Capitani, S. Burnell, T. Rees, K. Smart, M. Somerville, A. Gallimore, M. Perera, M. Potts, M. Metaxaki, B. Krishna, H. Jackson, P. Tighe, D. Onion, A. Godkin, M. Wills and L. Fairclough (2024). "Lower Humoral and Cellular Immunity Following Asymptomatic SARS-CoV-2 Infection Compared to Symptomatic Infection in Education (The ACE Cohort)." J Clin Immunol 44(6): 147.

Hopkinson, A., M. Notara, C. Cursiefen and L. E. Sidney (2024). "Increased Anti-Inflammatory Therapeutic Potential and Progenitor Marker Expression of Corneal Mesenchymal Stem Cells Cultured in an Optimized Propagation Medium." Cell Transplantation 33: 09636897241241992.

Jain, A., J. Gosling, S. Liu, H. Wang, E. M. Stone, S. Chakraborty, P. S. Jayaraman, S. Smith, D. B. Amabilino, M. Fromhold, Y. T. Long, L. Perez-Garcia, L. Turyanska, R. Rahman and F. J. Rawson (2024). "Wireless electrical-molecular quantum signalling for cancer cell apoptosis." Nat Nanotechnol 19(1): 106-114.

Marelli, E., J. Hughes and P. J. Scotting (2024). "SUMO-dependent transcriptional repression by Sox2 inhibits the proliferation of neural stem cells." Plos one 19(3): e0298818.

Mitchell-White, J. I., D. A. Briggs, S. J. Mistry, H. A. Mbiwan, B. Kellam, N. D. Holliday, S. J. Briddon and I. D. Kerr (2024). "A time-resolved Förster resonance energy transfer assay to investigate drug and inhibitor binding to ABCG2." Archives of Biochemistry and Biophysics: 109915.

Musa, M., M. Abid, T. D. Bradshaw, D. J. Boocock, C. Coveney, S. P. Argent and S. Woodward (2024). "Probing the Mechanism of Action of Bis (phenolato) Amine (ONO Donor Set) Titanium (IV) Anticancer Agents." Journal of Medicinal Chemistry.

Tomes, A., N. Archer and J. Leigh (2024). "Reproducible isolation of bovine mammary macrophages for analysis of host pathogen interactions." BMC Veterinary Research 20(1): 96.

 

2023

Publications from 2023

Alblihy, A., R. Ali, M. Algethami, A. A. Ritchie, A. Shoqafi, S. Alqahtani, K. A. Mesquita, M. S. Toss, P. Ordóñez-Morán and J. N. Jeyapalan (2023). "Selective Killing of BRCA2-Deficient Ovarian Cancer Cells via MRE11 Blockade." International journal of molecular sciences 24(13): 10966.

Algethami, M., M. S. Toss, C. L. Woodcock, C. Jaipal, J. Brownlie, A. Shoqafi, A. Alblihy, K. A. Mesquita, A. R. Green and N. P. Mongan (2023). "Unravelling the clinicopathological and functional significance of replication protein A (RPA) heterotrimeric complex in breast cancers." NPJ Breast Cancer 9(1): 18.

Alobaid, M. A. (2023). "Optimizing the viability, stability, and potency of Buffy coat isolated T cells for homologous dendritic cell co-cultures: A method for handling and preservation." Journal of Immunological Methods 515: 113454.

Gao, X. and U. Bayraktutan (2023). "Substance P reversibly compromises the integrity and function of blood-brain barrier." Peptides 167: 171048.

Giehl, R. F., P. Flis, J. Fuchs, Y. Gao, D. E. Salt and N. Von Wirén (2023). "Cell type-specific mapping of ion distribution in Arabidopsis thaliana roots." Nature Communications 14(1): 3351.

Gomez, N. E., V. James, K. P. Arkill, Z. A. Nizamudeen, D. Onion and L. C. Fairclough (2023). "PBMC‐derived extracellular vesicles in a smoking‐related inflammatory disease model." European Journal of Immunology 53(6): 2250143.

Gumber, L., N. Gomez, G. Hopkins, D. Tucis, L. Bartlett, K. Ayling, K. Vedhara, G. Steers, M. Chakravorty, M. Rutter, H. Jackson, P. Tighe, A. Ferraro, S. Power, M. J. Pradere, D. Onion, P. C. Lanyon, F. A. Pearce and L. Fairclough (2023). "Humoral and cellular immunity in patients with rare autoimmune rheumatic diseases following SARS-CoV-2 vaccination." Rheumatology (Oxford) 62(6): 2294-2303.

Gumus, N., C. Gunduz and B. Tezcanli Kaymaz (2023). "STAT5 inhibitor Pimozide as a probable therapeutic option in overcoming Ponatinib resistance in K562 leukemic cells." Journal of Biomolecular Structure and Dynamics 41(1): 186-199.

Harvey, H. J., A. C. Hendry, M. Chirico, D. B. Archer and S. V. Avery (2023). "Adaptation to sorbic acid in low sugar promotes resistance of yeast to the preservative." Heliyon 9(11).

Hopkins, G. V., S. Cochrane, D. Onion and L. C. Fairclough (2023). "Invariant NKT cells are more abundant in peanut-allergic adults and a subset of CD8(+) iNKT cells are depleted after peanut oil exposure." Front Immunol 14: 1293158.

Kadir, R. R. A., M. Alwjwaj, K. Rakkar, O. A. Othman, N. Sprigg, P. M. Bath and U. Bayraktutan (2023). "Outgrowth endothelial cell conditioned medium negates TNF-α-evoked cerebral barrier damage: A reverse translational research to explore mechanisms." Stem Cell Reviews and Reports 19(2): 503-515.

Kadir, R. R. A., K. Rakkar, O. A. Othman, N. Sprigg, P. M. Bath and U. Bayraktutan (2023). "Analysis of endothelial progenitor cell subtypes as clinical biomarkers for elderly patients with ischaemic stroke." Scientific Reports 13(1): 21843.

Kosar, M., D. A. Sykes, A. E. G. Viray, R. M. Vitale, R. C. Sarott, R. L. Ganzoni, D. Onion, J. M. Tobias, P. Leippe, C. Ullmer, E. A. Zirwes, W. Guba, U. Grether, J. A. Frank, D. B. Veprintsev and E. M. Carreira (2023). "Platform Reagents Enable Synthesis of Ligand-Directed Covalent Probes: 糖心原创 of Cannabinoid Receptor 2 in Live Cells." J Am Chem Soc 145(28): 15094-15108.

Rehmani, S., C. M. McLaughlin, H. M. Eltaher, C. R. Moffett, P. R. Flatt and J. E. Dixon (2023). "Orally-delivered insulin-peptide nanocomplexes enhance transcytosis from cellular depots and improve diabetic blood glucose control." Journal of Ophthalmology Clinics and Research 360: 93-109.

Tanasescu, R., N. Frakich, I.-J. Chou, P. Filippini, G. Podda, G. Xin, R. Muraleedharan, O. Jerca, D. Onion and C. S. Constantinescu (2023). "Natalizumab Treatment of Relapsing Remitting Multiple Sclerosis Has No Long-Term Effects on the Proportion of Circulating Regulatory T Cells." Neurology and Therapy 12(6): 2041-2052.

 

2022

Publications from 2022

Abuzaid, H., S. Abdelrazig, L. Ferreira, H. M. Collins, D.-H. Kim, K.-H. Lim, T.-S. Kam, L. Turyanska and T. D. Bradshaw (2022). "Apoferritin-encapsulated Jerantinine a for transferrin receptor targeting and enhanced selectivity in breast Cancer therapy." ACS omega 7(25): 21473-21482.

Al-Dalawi, L., S. P. Dunham and C. Rauch (2022). "Lipid biophysics and/or soft matter-inspired approach for controlling enveloped virus infectivity." Journal of the Royal Society Interface 19(189): 20210943.

Al-Natour, M. A., S. Abdelrazig, A. M. Ghaemmaghami, C. Alexander and D.-H. Kim (2022). "Metabolic signatures of surface-modified poly (lactic-co-glycolic acid) nanoparticles in differentiated THP-1 cells derived with liquid chromatography-mass spectrometry-based metabolomics." ACS omega 7(33): 28806-28819.

Alblihy, A., R. Ali, M. Algethami, A. Shoqafi, M. S. Toss, J. Brownlie, N. J. Tatum, I. Hickson, P. O. Moran and A. Grabowska (2022). "Targeting Mre11 overcomes platinum resistance and induces synthetic lethality in XRCC1 deficient epithelial ovarian cancers." NPJ precision oncology 6(1): 51.

Augostine, C. R. and S. V. Avery (2022). "Discovery of natural products with antifungal potential through combinatorial synergy." Frontiers in Microbiology 13: 866840.

Awuah, D., A. Ruisinger, M. Alobaid, C. Mbadugha and A. M. Ghaemmaghami (2022). "MicroRNA-511-3p mediated modulation of the peroxisome proliferator-activated receptor gamma (PPARγ) controls LPS-induced inflammatory responses in human monocyte derived DCs." Immuno 2(1): 104-117.

Branter, J., M. Estevez-Cebrero, M. Diksin, M. Griffin, M. Castellanos-Uribe, S. May, R. Rahman, R. Grundy, S. Basu and S. Smith (2022). "Genome-wide expression and anti-proliferative effects of electric field therapy on pediatric and adult brain tumors." International journal of molecular sciences 23(4): 1982.

Catania, R., D. Onion, E. Russo, M. Zelzer, G. Mantovani, A. Huett and S. Stolnik (2022). "A mechanoresponsive nano-sized carrier achieves intracellular release of drug on external ultrasound stimulus." RSC advances 12(26): 16561-16569.

Gao, X., N. Frakich, P. Filippini, L. J. Edwards, U. Vinkemeier, B. Gran, R. Tanasescu, U. Bayraktutan, S. Colombo and C. S. Constantinescu (2022). "Effects of substance P on human cerebral microvascular endothelial cell line hCMEC/D3 are mediated exclusively through a truncated NK-1 receptor and depend on cell confluence." Neuropeptides 95: 102265.

Harvey, H. J., M. V. Chubynsky, J. E. Sprittles, L. M. Shor, S. J. Mooney, R. D. Wildman and S. V. Avery (2022). "Application of microfluidic systems in modelling impacts of environmental structure on stress-sensing by individual microbial cells." Computational and Structural Biotechnology Journal 20: 128-138.

Mastrotto, F., M. Pirazzini, S. Negro, A. Salama, L. Martinez-Pomares and G. Mantovani (2022). "Sulfation at Glycopolymer Side Chains Switches Activity at the Macrophage Mannose Receptor (CD206) In Vitro and In Vivo." Journal of the American Chemical Society 144(50): 23134-23147.

Mehmood, H., M. Musa, S. Woodward, M. S. Hossan, T. D. Bradshaw, M. Haroon, A. Nortcliffe and T. Akhtar (2022). "Design, and synthesis of selectively anticancer 4-cyanophenyl substituted thiazol-2-ylhydrazones." RSC advances 12(52): 34126-34141.

Prakash, P. S., N. J. Barwary, M. H. Weber, D. Wan, I. Conejeros, B. Pereira Moreira, W. S. Alharbi, J. J. van Hellemond, J. Akinwale and F. H. Falcone (2022). "The Humanised NPY-mRFP RBL Reporter Cell Line Is a Fast and Inexpensive Tool for Detection of Allergen-Specific IgE in Human Sera." Diagnostics 12(9): 2063.

Saleh, M. M., D. A. Abuarqoub, A. M. Hammad, M. S. Hossan, N. Ahmed, N. Aslam, A. Y. Naser, C. J. Moody, C. A. Laughton and T. D. Bradshaw (2022). "In Vitro Anticancer Properties of Novel Bis-Triazoles." Current Issues in Molecular Biology 45(1): 175-196.

Stott-Marshall, R. J. and T. L. Foster (2022). "Inhibition of Arenavirus Entry and Replication by the Cell-Intrinsic Restriction Factor ZMPSTE24 Is Enhanced by IFITM Antiviral Activity." Front Microbiol 13: 840885.

Tidy, A. C., I. Ferjentsikova, G. Vizcay-Barrena, B. Liu, W. Yin, J. D. Higgins, J. Xu, D. Zhang, D. Geelen and Z. A. Wilson (2022). "Sporophytic control of pollen meiotic progression is mediated by tapetum expression of ABORTED MICROSPORES." Journal of Experimental Botany 73(16): 5543-5558.

 Travanut, A., P. F. Monteiro, S. Smith, S. M. Howdle, A. M. Grabowska, B. Kellam, M. A. Meier and C. Alexander (2022). "Passerini chemistries for synthesis of polymer pro-drug and polymersome drug delivery nanoparticles." Journal of Materials Chemistry B 10(20): 3895-3905.

Wood, J., S. Abdelrazig, S. Evseev, C. Ortori, M. Castellanos-Uribe, S. T. May, D. A. Barrett, M. Diksin, S. Chakraborty and D.-H. Kim (2022). "Lipoprotein Deprivation Reveals a Cholesterol-Dependent Therapeutic Vulnerability in Diffuse Glioma Metabolism." Cancers 14(16): 3873.

Wörtz, J., V. Smith, J. Fallmann, S. König, T. Thuraisingam, P. Walther, H. Urlaub, P. F. Stadler, T. Allers and F. Hille (2022). "Cas1 and Fen1 display equivalent functions during archaeal DNA repair." Frontiers in microbiology 13: 822304.

 

2021

Publications from 2021

Akhtar, R., H. Tahir, E. Stewart, R. Wei, I. Mohammed and W. M. Amoaku (2021). "Toll-like receptor signalling pathways regulate hypoxic stress induced fibroblast growth factor but not vascular endothelial growth factor-a in human microvascular endothelial cells." International Journal of Translational Medicine 1(1): 25-38.

Al-Ani, A. W., F. Zamberlan, L. Ferreira, T. D. Bradshaw, N. R. Thomas and L. Turyanska (2021). "Near-infrared PbS quantum dots functionalized with affibodies and ZnPP for targeted imaging and therapeutic applications." Nano Express 2(4): 040005.

Al-Hayali, M., A. Garces, M. Stocks, H. Collins and T. D. Bradshaw (2021). "Concurrent reactive oxygen species generation and aneuploidy induction contribute to thymoquinone anticancer activity." Molecules 26(17): 5136.

Alblihy, A., M. L. Alabdullah, R. Ali, M. Algethami, M. S. Toss, N. P. Mongan, E. A. Rakha and S. Madhusudan (2021). "Clinicopathological and functional evaluation reveal NBS1 as a predictor of platinum resistance in epithelial ovarian cancers." Biomedicines 9(1): 56.

Appleton, J. P., C. Richardson, N. Dovlatova, J. May, N. Sprigg, S. Heptinstall and P. M. Bath (2021). "Remote platelet function testing using P-selectin expression in patients with recent cerebral ischaemia on clopidogrel." Stroke and Vascular Neurology 6(1).

Awuah-Mensah, G., J. McDonald, P. C. Steketee, D. Autheman, S. Whipple, S. D'Archivio, C. Brandt, S. Clare, K. Harcourt and G. J. Wright (2021). "Reliable, scalable functional genetics in bloodstream-form Trypanosoma congolense in vitro and in vivo." PLoS pathogens 17(1): e1009224.

Bass, J. J., A. A. Kazi, C. S. Deane, A. Nakhuda, S. P. Ashcroft, M. S. Brook, D. J. Wilkinson, B. E. Phillips, A. Philp and J. Tarum (2021). "The mechanisms of skeletal muscle atrophy in response to transient knockdown of the vitamin D receptor in vivo." The Journal of physiology 599(3): 963-979.

Catania, R., F. Mastrotto, C. J. Moore, C. Bosquillon, F. H. Falcone, A. Huett, G. Mantovani and S. Stolnik (2021). "糖心原创 on Significance of Receptor Targeting in Killing of Intracellular Bacteria with Membrane‐Impermeable Antibiotics." Advanced Therapeutics 4(12): 2100168.

Hossan, M. S., M. K. B. Break, T. D. Bradshaw, H. M. Collins, C. Wiart, T.-J. Khoo and A. Alafnan (2021). "Novel semi-synthetic Cu (II)–cardamonin complex exerts potent anticancer activity against triple-negative breast and pancreatic cancer cells via inhibition of the Akt signaling pathway." Molecules 26(8): 2166.

Jambari, N. N., S. Liddell, L. Martinez-Pomares and M. J. Alcocer (2021). "Effect of O-linked glycosylation on the antigenicity, cellular uptake and trafficking in dendritic cells of recombinant Ber e 1." PloS one 16(4): e0249876.

Kaneko, K. and K. Robinson (2021). "Analysis of T Cell Responses to Helicobacter pylori Infection." Helicobacter Pylori: 215-223.

Karyal, C., P. Palazi, J. Hughes, R. C. Griffiths, R. R. Persaud, P. J. Tighe, N. J. Mitchell and R. Griffin (2021). "Mimicking native display of CD0873 on liposomes augments its potency as an oral vaccine against clostridioides difficile." Vaccines 9(12): 1453.

Moirangthem, K., P. Ramakrishna, M. H. Amer and G. A. Tucker (2021). "Bioactivity and anthocyanin content of microwave-assisted subcritical water extracts of Manipur black rice (Chakhao) bran and straw." Future Foods 3: 100030.

Nizamudeen, Z. A., R. Xerri, C. Parmenter, K. Suain, R. Markus, L. Chakrabarti and V. Sottile (2021). "Low-power sonication can alter extracellular vesicle size and properties." Cells 10(9): 2413.

Petch, J. E., P. Gurnani, G. Yilmaz, F. Mastrotto, C. Alexander, S. Heeb, M. Cámara and G. Mantovani (2021). "Combining Inducible Lectin Expression and Magnetic Glyconanoparticles for the Selective Isolation of Bacteria from Mixed Populations." ACS Applied Materials & Interfaces 13(16): 19230-19243.

Singh, S., Y. Almuhanna, M. Y. Alshahrani, D. W. Lowman, P. J. Rice, C. Gell, Z. Ma, B. Graves, D. Jackson and K. Lee (2021). "Carbohydrates from Pseudomonas aeruginosa biofilms interact with immune C-type lectins and interfere with their receptor function." npj Biofilms and Microbiomes 7(1): 87.

Taresco, V., T. F. Abelha, R. J. Cavanagh, C. E. Vasey, A. B. Anane‐Adjei, A. K. Pearce, P. F. Monteiro, K. A. Spriggs, P. Clarke and A. Ritchie (2021). "Functionalized Block Co‐Polymer Pro‐Drug Nanoparticles with Anti‐Cancer Efficacy in 3D Spheroids and in an Orthotopic Triple Negative Breast Cancer Model." Advanced Therapeutics 4(1): 2000103.

Zhu, Q., F. Sang, S. Withey, W. Tang, S. Dietmann, D. Klisch, P. Ramos-Ibeas, H. Zhang, C. E. Requena and P. Hajkova (2021). "Specification and epigenomic resetting of the pig germline exhibit conservation with the human lineage." Cell Reports 34(6).

 

2020

Publications from 2020

Abakir, A., T. C. Giles, A. Cristini, J. M. Foster, N. Dai, M. Starczak, A. Rubio-Roldan, M. Li, M. Eleftheriou and J. Crutchley (2020). "N 6-methyladenosine regulates the stability of RNA: DNA hybrids in human cells." Nature genetics 52(1): 48-55.

 Abdulkadir, R. R., M. Alwjwaj, O. A. Othman, K. Rakkar and U. Bayraktutan (2020). "Outgrowth endothelial cells form a functional cerebral barrier and restore its integrity after damage." Neural regeneration research 15(6): 1071-1078.

Abelha, T. F., G. Morris, S. M. Lima, L. H. Andrade, A. J. McLean, C. Alexander, J. Calvo‐Castro and C. J. McHugh (2020). "Development of a neutral diketopyrrolopyrrole phosphine oxide for the selective bioimaging of mitochondria at the nanomolar level." Chemistry–A European Journal 26(14): 3173-3180.

Abo-zeid, Y. and M. C. Garnett (2020). "Polymer nanoparticle as a delivery system for ribavirin: Do nanoparticle avoid uptake by Red Blood Cells?" Journal of Drug Delivery Science and Technology 56: 101552.

Alblihy, A., M. L. Alabdullah, M. S. Toss, M. Algethami, N. P. Mongan, E. A. Rakha and S. Madhusudan (2020). "RAD50 deficiency is a predictor of platinum sensitivity in sporadic epithelial ovarian cancers." Molecular Biomedicine 1: 1-10.

Ali, R., A. Alblihy, M. S. Toss, M. Algethami, R. Al Sunni, A. R. Green, E. A. Rakha and S. Madhusudan (2020). "XRCC1 deficient triple negative breast cancers are sensitive to ATR, ATM and Wee1 inhibitor either alone or in combination with olaparib." Therapeutic Advances in Medical Oncology 12: 1758835920974201.

Alobaid, M. A., S.-J. Richards, M. R. Alexander, M. I. Gibson and A. M. Ghaemmaghami (2020). "Developing immune-regulatory materials using immobilized monosaccharides with immune-instructive properties." Materials Today Bio 8: 100080.

Aram, J., N. Frakich, E. Morandi, M. Alrouji, A. Samaraweera, D. Onion, I. Spendlove, S. L. Colombo, R. Tanasescu and B. Gran (2020). "Increased IL-2 and reduced TGF-β upon T-cell stimulation are associated with GM-CSF upregulation in multiple immune cell types in multiple sclerosis." Biomedicines 8(7): 226.

Blokpoel Ferreras, L. A., S. Y. Chan, S. Vazquez Reina and J. E. Dixon (2020). "Rapidly transducing and spatially localized magnetofection using peptide-mediated non-viral gene delivery based on iron oxide nanoparticles." ACS Applied Nano Materials 4(1): 167-181.

Chen, I.-L., I. Todd, P. J. Tighe and L. C. Fairclough (2020). "Electronic cigarette vapour moderately stimulates pro-inflammatory signalling pathways and interleukin-6 production by human monocyte-derived dendritic cells." Archives of toxicology 94: 2097-2112.

Hanko, E. K., A. C. Paiva, M. Jonczyk, M. Abbott, N. P. Minton and N. Malys (2020). "A genome-wide approach for identification and characterisation of metabolite-inducible systems." Nature communications 11(1): 1213.

Jalal, A. R. and J. E. Dixon (2020). "Efficient delivery of transducing polymer nanoparticles for gene-mediated induction of osteogenesis for bone regeneration." Frontiers in Bioengineering and Biotechnology 8: 849.

Kapoor, P., D. A. Briggs, M. H. Cox and I. D. Kerr (2020). "Disruption of the Unique ABCG-family NBD: NBD interface impacts both drug transport and ATP hydrolysis." International journal of molecular sciences 21(3): 759.

Kargaran, P. K., J. M. Evans, S. E. Bodbin, J. G. Smith, T. J. Nelson, C. Denning and D. Mosqueira (2020). "Mitochondrial DNA: hotspot for potential gene modifiers regulating hypertrophic cardiomyopathy." Journal of Clinical Medicine 9(8): 2349.

Kirkham, G. R., J. Ware, T. Upton, S. Allen, K. M. Shakesheff and L. D. Buttery (2020). "Localized induction of gene expression in embryonic stem cell aggregates using holographic optical tweezers to create biochemical gradients." Regenerative Engineering and Translational Medicine 6: 251-261.

Makhafola, T. J., M. Mbele, K. Yacqub-Usman, A. Hendren, D. B. Haigh, Z. Blackley, M. Meyer, N. P. Mongan, D. O. Bates and Z. Dlamini (2020). "Apoptosis in cancer cells is induced by alternative splicing of hnRNPA2/B1 through splicing of Bcl-x, a mechanism that can be stimulated by an extract of the South African Medicinal Plant, Cotyledon orbiculata." Frontiers in Oncology 10: 547392.

Mohammed, I., B. Kulkarni, L. A. Faraj, A. Abbas, H. S. Dua and A. J. King (2020). "Profiling ocular surface responses to preserved and non‐preserved topical glaucoma medications: a 2‐year randomized evaluation study." Clinical & experimental ophthalmology 48(7): 973-982.

Monteiro, P. F., M. Gulfam, C. J. Monteiro, A. Travanut, T. F. Abelha, A. K. Pearce, C. Jerôme, A. M. Grabowska, P. A. Clarke and H. M. Collins (2020). "Synthesis of micellar-like terpolymer nanoparticles with reductively-cleavable cross-links and evaluation of efficacy in 2D and 3D models of triple negative breast cancer." Journal of controlled release 323: 549-564.

Rostam, H. M., L. E. Fisher, A. L. Hook, L. Burroughs, J. C. Luckett, G. P. Figueredo, C. Mbadugha, A. C. Teo, A. Latif and L. Kämmerling (2020). "Immune-instructive polymers control macrophage phenotype and modulate the foreign body response in vivo." Matter 2(6): 1564-1581.

Ruiter, F., L. Sidney, K. Kiick, J. Segal, C. Alexander and F. Rose (2020). "The electrospinning of a thermo-responsive polymer with peptide conjugates for phenotype support and extracellular matrix production of therapeutically relevant mammalian cells." Biomaterials science 8(9): 2611-2626.

Smith, S. J., J. Rowlinson, M. Estevez-Cebrero, D. Onion, A. Ritchie, P. Clarke, K. Wood, M. Diksin, A. Lourdusamy and R. G. Grundy (2020). "Metabolism-based isolation of invasive glioblastoma cells with specific gene signatures and tumorigenic potential." Neuro-oncology advances 2(1): vdaa087.

Sodano, F., R. J. Cavanagh, A. K. Pearce, L. Lazzarato, B. Rolando, A. Fraix, T. F. Abelha, C. E. Vasey, C. Alexander and V. Taresco (2020). "Enhancing doxorubicin anticancer activity with a novel polymeric platform photoreleasing nitric oxide." Biomaterials science 8(5): 1329-1344.

Stratford, M., C. Vallières, I. A. Geoghegan, D. B. Archer and S. V. Avery (2020). "The preservative sorbic acid targets respiration, explaining the resistance of fermentative spoilage yeast species." Msphere 5(3): 10.1128/msphere. 00273-00220.

Tanasescu, R., C. R. Tench, C. S. Constantinescu, G. Telford, S. Singh, N. Frakich, D. Onion, D. P. Auer, B. Gran and N. Evangelou (2020). "Hookworm treatment for relapsing multiple sclerosis: a randomized double-blinded placebo-controlled trial." JAMA neurology 77(9): 1089-1098.

Tellier, M. and R. Chalmers (2020). "Compensating for over-production inhibition of the Hsmar1 transposon in Escherichia coli using a series of constitutive promoters." Mobile DNA 11(1): 5.

Tivadar, S. T., R. S. McIntosh, J. X. Chua, R. Moss, T. Parsons, A. M. Zaitoun, S. Madhusudan, L. G. Durrant and M. Vankemmelbeke (2020). "Monoclonal antibody targeting sialyl-di-Lewisa–containing internalizing and noninternalizing glycoproteins with cancer immunotherapy development potential." Molecular Cancer Therapeutics 19(3): 790-801.

Vallières, C., N. Singh, C. Alexander and S. V. Avery (2020). "Repurposing nonantifungal approved drugs for synergistic targeting of fungal pathogens." ACS Infectious Diseases 6(11): 2950-2958.

Vankemmelbeke, M., R. S. McIntosh, J. X. Chua, T. Kirk, I. Daniels, M. Patsalidou, R. Moss, T. Parsons, D. Scott and G. Harris (2020). "Engineering the Human Fc Region Enables Direct Cell Killing by Cancer Glycan–Targeting Antibodies without the Need for Immune Effector Cells or Complement." Cancer research 80(16): 3399-3412.

 

2019

Publications from 2019

Al-Ani, A. W., L. Zhang, L. Ferreira, L. Turyanska, T. D. Bradshaw and N. R. Thomas (2019). "Listeria innocua Dps as a nanoplatform for bioluminescence based photodynamic therapy utilizing Gaussia princeps luciferase and zinc protoporphyrin IX." Nanomedicine: Nanotechnology, Biology and Medicine 20: 102005.

Alazzo, A., M. A. Al-Natour, K. Spriggs, S. Stolnik, A. Ghaemmaghami, D.-H. Kim and C. Alexander (2019). "Investigating the intracellular effects of hyperbranched polycation–DNA complexes on lung cancer cells using LC-MS-based metabolite profiling." Molecular Omics 15(1): 77-87.

Ali, E. A., M. Kalli, D. Wan, R. Nakamura, D. Onion, D. G. Alanine, M. J. Alcocer and F. H. Falcone (2019). "Characterization of human FcεRIα chain expression and gene copy number in humanized rat basophilic leukaemia (RBL) reporter cell lines." Plos one 14(8): e0221034.

Ali, R., M. Alabdullah, I. Miligy, M. Normatova, R. Babaei-Jadidi, A. S. Nateri, E. A. Rakha and S. Madhusudan (2019). "ATM regulated PTEN degradation is XIAP E3 ubiquitin ligase mediated in p85α deficient cancer cells and influence platinum sensitivity." Cells 8(10): 1271.

Almars, A., P. S. Chondrou, E. K. Onyido, S. Almozyan, C. Seedhouse, R. Babaei-Jadidi and A. S. Nateri (2019). "Increased FLYWCH1 expression is negatively correlated with Wnt/β-catenin target gene expression in acute myeloid leukemia cells." International Journal of Molecular Sciences 20(11): 2739.

Appleton, J. P., G. W. Blair, K. Flaherty, Z. K. Law, J. May, L. J. Woodhouse, F. Doubal, N. Sprigg, P. M. Bath and J. M. Wardlaw (2019). "Effects of isosorbide mononitrate and/or cilostazol on hematological markers, platelet function, and hemodynamics in patients with lacunar ischaemic stroke: safety data from the lacunar Intervention-1 (LACI-1) trial." Frontiers in neurology 10: 723.

Awuah, D., M. Alobaid, A. Latif, F. Salazar, R. D. Emes and A. M. Ghaemmaghami (2019). "The cross-talk between miR-511-3p and C-type lectin receptors on dendritic cells affects dendritic cell function." The Journal of Immunology 203(1): 148-157.

Blair, G. W., J. P. Appleton, K. Flaherty, F. Doubal, N. Sprigg, R. Dooley, C. Richardson, I. Hamilton, Z. K. Law and Y. Shi (2019). "Tolerability, safety and intermediary pharmacological effects of cilostazol and isosorbide mononitrate, alone and combined, in patients with lacunar ischaemic stroke: the LACunar Intervention-1 (LACI-1) trial, a randomised clinical trial." EClinicalMedicine 11: 34-43.

Breen, A. F., G. Wells, L. Turyanska and T. D. Bradshaw (2019). "Development of novel apoferritin formulations for antitumour benzothiazoles." Cancer Reports 2(4): e1155.

Da Silva, R. A., A. V. Karlyshev, N. J. Oldfield, K. G. Wooldridge, C. D. Bayliss, A. Ryan and R. Griffin (2019). "Variant signal peptides of vaccine antigen, FHbp, impair processing affecting surface localization and antibody-mediated killing in most meningococcal isolates." Frontiers in Microbiology 10: 498472.

Fox, S. C., J. A. May, N. Dovlatova, J. R. Glenn, A. Johnson, A. E. White, A. Radhakrishnan and S. Heptinstall (2019). "How does measurement of platelet P-selectin compare with other methods of measuring platelet function as a means of determining the effectiveness of antiplatelet therapy?" Platelets 30(3): 290-295.

Hanko, E. K., N. P. Minton and N. Malys (2019). Design, cloning and characterization of transcription factor-based inducible gene expression systems. Methods in Enzymology, Elsevier. 621: 153-169.

Harrison, R. P., V. M. Chauhan, D. Onion, J. W. Aylott and V. Sottile (2019). "Intracellular processing of silica-coated superparamagnetic iron nanoparticles in human mesenchymal stem cells." RSC advances 9(6): 3176-3184.

Hossan, M. S., Z.-Y. Chan, H. M. Collins, F. N. Shipton, M. S. Butler, M. Rahmatullah, J. B. Lee, P. Gershkovich, L. Kagan and T.-J. Khoo (2019). "Cardiac glycoside cerberin exerts anticancer activity through PI3K/AKT/mTOR signal transduction inhibition." Cancer letters 453: 57-73.

Junior, J. C. Q., F. d. R. R. Carlos, A. Montanari, A. Leitao, V. W. Mignone, M. A. Arruda, L. Turyanska and T. D. Bradshaw (2019). "Apoferritin encapsulation of cysteine protease inhibitors for cathepsin L inhibition in cancer cells." RSC advances 9(63): 36699-36706.

Kandiyil, N., S. T. MacSweeney, S. Heptinstall, J. May, S. C. Fox and D. P. Auer (2019). "Circulating microparticles in patients with symptomatic carotid disease are related to embolic plaque activity and recent cerebral ischaemia." Cerebrovascular Diseases Extra 9(1): 9-18.

Keerthiraju, E., C. Du, G. Tucker and D. Greetham (2019). "A role for COX20 in tolerance to oxidative stress and programmed cell death in Saccharomyces cerevisiae." Microorganisms 7(11): 575.

Mesquita, K. A., M. Alabdullah, M. Griffin, M. S. Toss, T. M. A. Fatah, A. Alblihy, P. Moseley, S. Y. Chan, E. A. Rakha and S. Madhusudan (2019). "ERCC1-XPF deficiency is a predictor of olaparib induced synthetic lethality and platinum sensitivity in epithelial ovarian cancers." Gynecologic oncology 153(2): 416-424.

Morandi, E., R. Tanasescu, R. E. Tarlinton, D. Constantin-Teodosiu and B. Gran (2019). "Do antiretroviral drugs protect from multiple sclerosis by inhibiting expression of MS-associated retrovirus?" Frontiers in immunology 9: 413066.

Mosqueira, D., K. Lis-Slimak and C. Denning (2019). "High-throughput phenotyping toolkit for characterizing cellular models of hypertrophic cardiomyopathy in vitro." Methods and protocols 2(4): 83.

Negm, O., S. Singh, W. Abduljabbar, M. Hamed, P. Radford, E. McDermott, E. Drewe, L. Fairclough, I. Todd and P. Tighe (2019). "Patients with tumour necrosis factor (TNF) receptor-associated periodic syndrome (TRAPS) are hypersensitive to Toll-like receptor 9 stimulation." Clinical & Experimental Immunology 197(3): 352-360.

Nieto-Orellana, A., H. Li, R. Rosiere, N. Wauthoz, H. Williams, C. J. Monteiro, C. Bosquillon, N. Childerhouse, G. Keegan and D. Coghlan (2019). "Targeted PEG-poly (glutamic acid) complexes for inhalation protein delivery to the lung." Journal of controlled release 316: 250-262.

Popov, A., C. Scotchford, D. Grant and V. Sottile (2019). "Impact of serum source on human mesenchymal stem cell osteogenic differentiation in culture." International journal of molecular sciences 20(20): 5051.

Sherman, H. G., C. Jovanovic, A. Abuawad, D.-H. Kim, H. Collins, J. E. Dixon, R. Cavanagh, R. Markus, S. Stolnik and F. J. Rawson (2019). "Mechanistic insight into heterogeneity of trans-plasma membrane electron transport in cancer cell types." Biochimica et Biophysica Acta (BBA)-Bioenergetics 1860(8): 628-639.

Tchoryk, A., V. Taresco, R. H. Argent, M. Ashford, P. R. Gellert, S. Stolnik, A. Grabowska and M. C. Garnett (2019). "Penetration and uptake of nanoparticles in 3D tumor spheroids." Bioconjugate chemistry 30(5): 1371-1384.

Tellier, M. and R. Chalmers (2019). "The roles of the human SETMAR (Metnase) protein in illegitimate DNA recombination and non-homologous end joining repair." DNA repair 80: 26-35.

Wang, R., R. Pscheid, A. Ghumra, L. Y. L. Kan, S. Cochrane, L. Fairclough and M. J. Alcocer (2019). "Towards a surrogate system to express human lipid binding TCRs." Biotechnology letters 41: 1095-1104.

 

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