GRIFFITHS, R. C., SMITH, F. R., LONG, J. E., SCOTT, D., WILLIAMS, H. E. L., OLDHAM, N. J., LAYFIELD, R. and MITCHELL, N. J., 2022. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 61, e202110223
BRENNAN, ANDREW, LAYFIELD, ROBERT, LONG, JED, WILLIAMS, HUW E L, OLDHAM, NEIL J, SCOTT, DANIEL and SEARLE, MARK S, 2022. An ALS-associated variant of the autophagy receptor SQSTM1/p62 reprograms binding selectivity toward the autophagy-related hATG8 proteins. The Journal of biological chemistry. 298(2), 101514
DONGDEM, JULIUS T., DAWSON, SIMON P. and LAYFIELD, ROBERT, 2021. PROTEOMICS. 21(15),
FOSTER, A. D., FLYNN, L. L., CLUNING, C., CHENG, F., DAVIDSON, J. M., LEE, A., POLAIN, N., MEJZINI, R., FARRAWELL, N., YERBURY, J. J., LAYFIELD, R., AKKARI, P. A. and REA, S. L., 2021. SCIENTIFIC REPORTS. 11(1),
WATSON, MORAG E., SCOTT, DANIEL, JAMIESON, CRAIG, LAYFIELD, ROBERT and MASON, ANDREW M., 2021. PEPTIDE SCIENCE. 113(1),
GRIFFITHS, RHYS C., SMITH, FRANCES R., LONG, JED E., WILLIAMS, HUW E. L., LAYFIELD, ROBERT and MITCHELL, NICHOLAS J., 2020. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 59(52), 23659-23667
FOSTER, A. D., DOWNING, P., FIGREDO, E., POLAIN, N., STOTT, A., LAYFIELD, R. and REA, S. L., 2020. MOLECULAR AND CELLULAR NEUROSCIENCE. 108,
FOGGIN, SOPHIE, MESQUITA-RIBEIRO, RAQUEL, DAJAS-BAILADOR, FEDERICO and LAYFIELD, ROB, 2019. FRONTIERS IN NEUROLOGY. 10,
SHAW, BARRY, BURRELL, CARLA L., GREEN, DARRELL, NAVARRO-MARTINEZ, ANA, SCOTT, DANIEL, DAROSZEWSKA, ANNA, VAN 'T HOF, ROB, SMITH, LYNN, HARGRAVE, FRANK, MISTRY, SHARAD, BOTTRILL, ANDREW, KESSLER, BENEDIKT M., FISCHER, ROMAN, SINGH, ARCHANA, DALMAY, TAMAS, FRASER, WILLIAM D., HENNEBERGER, KIRSTIN, KING, TURI, GONZALEZ, SILVIA and LAYFIELD, ROBERT, 2019. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 116(21), 10463-10472
DUCKER, CHARLES, CHOW, LEO KAM YUEN, SAXTON, JANICE, HANDWERGER, JURGEN, MCGREGOR, ALEXANDER, STRAHL, THOMAS, LAYFIELD, ROBERT and SHAW, PETER E, 2019. NUCLEIC ACIDS RESEARCH. 47(9), 4495-4508
FOSTER, A, SCOTT, D, LAYFIELD, R and REA, S L, 2019. MOLECULAR AND CELLULAR NEUROSCIENCE. 98, 32-45
RALSTON, STUART H., CORRAL-GUDINO, LUIS, COOPER, CYRUS, FRANCIS, ROGER M., FRASER, WILLIAM D., GENNARI, LUIGI, GUANABENS, NURIA, JAVAID, M. KASSIM, LAYFIELD, ROBERT, O'NEILL, TERENCE W., RUSSELL, ROBERT GRAHAM G., STONE, MICHAEL D., SIMPSON, KEITH, WILKINSON, DIANA, WILLS, RUTH, ZILLIKENS, M. CAROLA and TUCK, STEPHEN P., 2019. JOURNAL OF BONE AND MINERAL RESEARCH. 34(12), 2327-2329
SERVANTE, JULIETTE, ESTRANERO, JASPER, MEIJER, LISETHE, LAYFIELD, ROB and GRUNDY, RICHARD, 2018. Chemical modulation of autophagy as an adjunct to chemotherapy in childhood and adolescent brain tumors. Oncotarget. 9(81), 35266-35277
PAUL TUCK S, LAYFIELD R, WALKER J, MEKKAYIL B and FRANCIS R, 2017. Rheumatology. (In Press.)
HAQUE F, VARLET P, PUNTONET J, STORER L, BOUNTALI A, RAHMAN R, GRILL J, CARCABOSO AM, JONES C, LAYFIELD R and GRUNDY RG, 2017. Acta neuropathologica communications. 5(1), 45
THOMAS B, MCINTOSH D, FILDES T, ISLAM M, THOMPSON T, LAYFIELD R, SCOTT D, SHAW B, BURRELL CL, GONZALEZ S and TAYLOR S, 2017. Second-Harmonic Generation Imaging of Collagen in Ancient Bone Bone Reports. (In Press.)
SCOTT D, GARNER TP, LONG J, STRACHAN J, MISTRY SC, BOTTRILL AR, TOOTH DJ, SEARLE MS, OLDHAM NJ and LAYFIELD R, 2016. Proteomics. 16(14), 1961-9
ZEROVNIK E, JERALA NK and LAYFIELD R, 2016. J Alzheimers Dis Parkinsonism. 5, 220
GOODE A, BUTLER K, LONG J, CAVEY J, SCOTT D, SHAW B, SOLLENBERGER J, GELL C, JOHANSEN T, OLDHAM NJ, SEARLE MS and LAYFIELD R, 2016. Autophagy. 12(7), 1094-104
SCOTT D, STRACHAN J, KRISHNA VG, SHAW B, TOOTH DJ, SEARLE MS, OLDHAM NJ and LAYFIELD R, 2016. Methods in Molecular Biology. 1449, 203-13
GOODE A, REA S, SULTANA M, SHAW B, SEARLE MS and LAYFIELD R, 2016. Molecular and Cellular Neurosciences. 76, 52-58
MANZI L, BARROW AS, SCOTT D, LAYFIELD R, WRIGHT TG, MOSES JE and OLDHAM NJ, 2016. Nature Communications. 7, 13288
HAFEEZ G, GALAZIS N, DOCHEVA N, LAYFIELD R and ATIOMO W, 2015. Human Reproduction. 30(1), 133-48
MAJCHER V, GOODE A, JAMES V and LAYFIELD R, 2015. Molecular and Cellular Neuroscience. 66, 43-52
SCOTT D, LAYFIELD R and OLDHAM NJ, 2015. Protein Science. 24(8), 1257-63
SCOTT, DANIEL, LAYFIELD, ROBERT and OLDHAM, NEIL J., 2015. PROTEOMICS. 15(16), 2835-2841
SCOTT, DANIEL, OLDHAM, NEIL J., STRACHAN, JO, SEARLE, MARK S. and LAYFIELD, ROBERT, 2015. PROTEOMICS. 15(5-6), 844-861
SHAPIRO IM, LAYFIELD R*, LOTZ M*, SETTEMBRE C* and WHITEHOUSE C*, 2014. Autophagy. 10(1), 7-19
HAOULA Z, SHAW B, DAYKIN C, HODGMAN C, LAYFIELD R and ATIOMO W, 2014. Gynecological Endocrinology. 30(3), 213-216
REA S, MAJCHER V, SEARLE MS and LAYFIELD R, 2014. Experimental Cell Research. 325, 27-37
GOODE A, LONG JE, SHAW B, RALSTON SH, VISCONTI MR, GIANFRANCESCO F, ESPOSITO T, GENNARI L, MERLOTTI D, RENDINA D, REA SL, SULTANA M, SEARLE MS and LAYFIELD R, 2014. BBA - Molecular Basis of Disease. 1842, 992-1000
WRIGHT T, REA S, GOODE A, BENNETT AJ, RATAJCZAK T, LONG JE, SEARLE MS, GOLDRING CE, PARK BK, COPPLE IM and LAYFIELD R, 2013. Bone. 52, 699-706
SOKRATOUS K, LAYFIELD R and OLDHAM NJ, 2013. The effects of cation adduction upon the conformation of three-helix bundle protein domains. International Journal for Ion Mobility Spectrometry. 16, 19-27
REA SL, WALSH JP, LAYFIELD R, RATAJCZAK T and XU J, 2013. Endocrine Reviews. 34, 501-524
GALAZIS N, PANG Y, GALAZI M, HAOULA Z, LAYFIELD R and ATIOMO W, 2013. Gynecological Endocrinology. 29(7), 638-44
TOOTH, D., GARSED, K., SINGH, G., MARCIANI, L., LAM, C., FORDHAM, I., FIELDS, A., BANWAIT, R., LINGAYA, M., LAYFIELD, R., HASTINGS, M., WHORWELL, P. and SPILLER, R., 2013. Gut. n/a(n/a), n/a
STRACHAN J, SHAW B, GOPALA KRISHNA V, SCOTT D, DEL POZO JC, HILL K, GAUTAM M, SKOWYRA D, JACOBSON AD, LIU CW, OLDHAM N and LAYFIELD R, 2013. Broad utility of an affinity-enrichment strategy for unanchored polyubiquitin chains Journal of Proteomics & Bioinformatics. S7, 1-7
GIANFRANCESCO F, RENDINA D, DI STEFANO M, MINGIONE A, ESPOSITO T, MERLOTTI D, GALLONE S, MAGLIOCCA S, GOODE A, FORMICOLA D, MORELLO G, LAYFIELD R, FRATTINI A, DE FILIPPO G, NUTI R, SEARLE M, STRAZZULLO P, ISAIA G, MOSSETTI G and GENNARI L, 2012. Journal of Bone and Mineral Research. 27, 443-452
CHADWICK L, GENTLE L, STRACHAN J and LAYFIELD R, 2012. Neuropathology and Applied Neurobiology. 38, 118-131
STRACHAN, J., ROACH, L., SOKRATOUS, K., TOOTH, D., LONG, J., GARNER, T.P., SEARLE, M.S., OLDHAM, N.J. and LAYFIELD, R., 2012. Journal of Proteome Research. 11(3), 1969-1980
SEARLE MS, GARNER TP, STRACHAN J, LONG J, ADLINGTON J, CAVEY JR, SHAW B and LAYFIELD R, 2012. Biochem Soc Transactions. 40(2), 404-408
SOKRATOUS, K., ROACH, L.V., CHANNING, D., STRACHAN, J., LONG, J., SEARLE, M.S., LAYFIELD, R. and OLDHAM, N.J., 2012. Journal of the American Chemical Society. 134(14), 6416-6424
RALSTON SH and LAYFIELD R, 2012. Calcified Tissue International. 91(2), 97-113
WOODS S, CLARKE NN, LAYFIELD R and FONE KCF, 2012. British Journal of Pharmacology. 167, 436-449
HOPPER JTS, RAWLINGS A, AFONSO JP, CHANNING D, LAYFIELD R and OLDHAM NJ, 2012. Journal of the American Society for Mass Spectrometry. 23(10), 1757-67
TOOTH DJ, KRISHNA VG and LAYFIELD R, 2012. International Journal of Proteomics. 2012, 735132
KLIONSKY DJ AND 1269 OTHERS, 2012. Autophagy. 8, 445-544
SOKRATOUS K, STRACHAN J, ROACH LV, LAYFIELD R and OLDHAM NJ, 2012. FEBS Letters. 586, 4144-4147
GALAZIS, N., OLALEYE, O., HAOULA, Z., LAYFIELD, R. and ATIOMO, W., 2012. Fertility and Sterility. 98(6), 1590-1601.e1
GARNER TP, LONG J, LAYFIELD R, SEARLE MS, 2011. Biochemistry. 50(21), 4665-74
BEDFORD L, LAYFIELD R, MAYER RJ, PENG J, XU P, 2011. Neuroscience Letters. 491(1), 44-7
DAROSZEWSKA A, VAN 'T HOF RJ, ROJAS JA, LAYFIELD R, LANDAO-BASONGA E, ROSE L, ROSE K, RALSTON SH, 2011. Human Molecular Genetics. 20(14), 2734-44
DORRIAN JM, BRIGGS DA, RIDLEY ML, LAYFIELD R, KERR ID, 2011. FEBS Journal. 278(21), 4015-24
GARNER, T.P., STRACHAN, J., SHEDDEN, E.C., LONG, J.E., CAVEY, J.R., SHAW, B., LAYFIELD, R. and SEARL, M.S., 2011. Biochemistry. 50(42), 9076-9087
BOH BK, NG MY, LECK YC, SHAW B, LONG J, SUN GW, GAN YH, SEARLE MS, LAYFIELD R and HAGEN T, 2011. Journal of Molecular Biology. 413(2), 430-7
HEINEN C, GARNER TP, LONG J, B脰TTCHER C, RALSTON SH, CAVEY JR, SEARLE MS, LAYFIELD R, DANTUMA NP, 2010. FEBS Letters. 584(8), 1585-90
GOODE A, LAYFIELD R, 2010. Journal of Clinical Pathology. 63(3), 199-203.
CERU S, LAYFIELD R, ZAVA艩NIK-BERGANT T, REPNIK U, KOPITAR-JERALA N, TURK V, ZEROVNIK E, 2010. Biology of the Cell. 102(6), 319-34.
ROGERS N, PAINE S, BEDFORD L, LAYFIELD R, 2010. Neuropathology and Applied Neurobiology. 36, 113-24.
LONG, J., GARNER, T.P., PANDYA, M.J., CRAVEN, C.J., CHEN, P., SHAW, B., WILLIAMSON, M.P., LAYFIELD, R. and SEARLE, M.S., 2010. Journal of Molecular Biology. 396(1), 178-194
COPPLE, IM, LISTER, A, OBENG, AD, KITTERINGHAM, NR, JENKINS, RE, LAYFIELD, R, FOSTER, BJ, GOLDRING, CE, PARK, BK, 2010. Journal of Biological Chemistry. 285, 16782-88
PAINE, S, BEDFORD, L, THORPE, JR, MAYER, RJ, CAVEY, JR, BAJAJ, N, SHEPPARD, PW, LOWE, J, LAYFIELD, R, 2009. Neuroscience Letters. 460(3), 205-8
MURTON, A.J., ALAMDARI, N., GARDINER, S.M., CONSTANTIN-TEODOSIU, D., LAYFIELD, R., BENNETT, T. and GREENHAFF, P.L., 2009. PLoS One. 4(9), e6945
CHUTHAPISITH, S, BEAN, B, COWLEY, G, EREMIN, JM, SAMPHAO, S, LAYFIELD, R, KERR, ID, WISEMAN, J, EL-SHEEMY, M, SREENIVASAN, T, EREMIN, O, 2009. European Journal of Cancer. 45(7), 1274-81
ATIOMO, W., KHALID, S., PARAMESHWERAN, S., HOUDA, M. and LAYFIELD, R., 2009. BJOG: an International Journal of Obstetrics & Gynecology. 116(2), 137-143
REA, SL,WALSH, JP, WARD, L, MAGNO, AL, WARD, BK, SHAW, B, LAYFIELD, R, KENT, GN, XU, J, RATAJCZAK, T, 2009. Journal of Bone and Mineral Research. 24(7), 1216-23
NAJAT, D., GARNER, T., HAGEN, T., SHAW, B., SHEPPARD, P.W., FALCHETTI, A., MARINI, F., BRANDI, M.L., LONG, J.E., CAVEY, J.R., SEARLE, M.S. and LAYFIELD, R., 2009. Journal of Bone and Mineral Research. 24(4), 632-642
ATIOMO, WU, KHALID, S, ZIAUDDIN, A, TOOTH, D, LAYFIELD, R, 2009. Expert Review of Proteomics. 6(5), 469-99
RUTLAND, C., WARNER, L., THORPE, A., ALIBHAI, A., ROBINSON, T., SHAW, B., LAYFIELD, R., BROOK, J.D. and LOUGHNA, S., 2009. Journal of Anatomy. 214(6), 905-915
BEDFORD, L., HAY, D., DEVOY, A., PAINE, S., POWE, D.G., SETH, R., GRAY, T., TOPHAM, I., FONE, K., REZVANI, N., MEE, M., SOANE, T., LAYFIELD, R., SHEPPARD, P.W., EBENDAL, T., USOSKIN, D., LOWE, J. and MAYER, R.J., 2008. Journal of Neuroscience. 28(33), 8189-8198
ALAMDARI, N., CONSTANTIN-TEODOSIU, D., MURTON, A.J., GARDINER, S.M., BENNETT, T., LAYFIELD, R. and GREENHAFF, P.L., 2008. Journal of Physiology. 586(6), 1767-1775
GREENHAFF, P.L., KARAGOUNIS, L.G., PIERCE, N,, SIMPSON, E.J., HAZELL, M., LAYFIELD, R., WACKERHAGE, H., SMITH, K., ATHERTON, P., SELBY, A. and RENNIE, M.J., 2008. American Journal of Physiology: Endocrinology and Metabolism. 295(3), E595-E604
LONG, J., GALLAGHER, T.R.A., CAVEY, J.R., SHEPPARD, P.W., RALSTON, S.H., LAYFIELD, R. and SEARLE, M.S., 2008. Journal of Biological Chemistry. 283(9), 5427-5440
LAYFIELD, R, SEARLE, MS, 2008. Biochemical Society Transactions. 36(Pt 3), 469-71
LAYFIELD R, MAYER RJ, 2008. Biochimica et Biophysica Acta. 1782(12), 681-2
CANEDA-FERR脫N, B, DE GIROLAMO, LA, COSTA, T, BECK, KE, LAYFIELD, R, BILLETT, EE, 2008. Journal of Neurochemistry. 105(1), 225-38
LAYFIELD, R, MATHAROO-BALL, B, 2008. Proteomics. 8(9), 1754-5
GREENHAFF, P. L., KARAGOUNIS, L. G., PEIRCE, N., SIMPSON, E. J., HAZELL, M., LAYFIELD, R., WACKERHAGE, H., SMITH, K., ATHERTON, P., SELBY, A. and RENNIE, M. J., 2008. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 295(3), E595-E604
ROLLAND, P., MADJD, Z., DURRANT, L., ELLIS, I.O., LAYFIELD, R. and SPENDLOVE, I., 2007. Endocrine-Related Cancer. 14(1), 73-80
ATHANASIOU, ANDRIANI, SMITH, PAUL A, VAKILPOUR, SARA, KUMARAN, NETHIA M, TURNER, AMY E, BAGIOKOU, DIMITRA, LAYFIELD, ROBERT, RAY, DAVID E, WESTWELL, ANDREW D, ALEXANDER, STEPHEN P H and KENDALL, DAVID A, 2007. Biochemical and Biophysical Research Communications. 354(1), 50-5
CONSTANTIN, CONSTANTIN-TEODOSIU, LAYFIELD, TSINTZAS, BENNETT, GREENHAFF, 2007. Journal of Physiology. 583(1), 381-390
CHUTHAPISITH, S, LAYFIELD, R, KERR, I D and EREMIN, O, 2007. The Surgeon. 5(1), 14-22
CHUTHAPISITH, S, LAYFIELD, R, KERR, ID, HUGHES, C, EREMIN, O, 2007. Proteomic profiling of MCF-7 breast cancer cells with chemoresistance to different types of anti-cancer drugs. International Journal of Oncology. 30(6), 1545-51
LAYFIELD, R, SHAW, B, 2007. BMC Biochemistry. 8 Suppl 1, S5
TOMLINSON, E, PALANIYAPPAN, N, TOOTH, D, LAYFIELD, R, 2007. Proteomics. 7(7), 1016-22
LAYFIELD, R, 2007. The molecular pathogenesis of Paget disease of bone. Expert Reviews in Molecular Medicine. 9(27), 1-13
MATHAROO-BALL, B, HUGHES, C, LANCASHIRE, L, TOOTH, D, BALL, G, CREASER, C, ELGASIM, M, REES, R, LAYFIELD, R and ATIOMO, W, 2007. Journal of Proteome Research. 6(8), 3321-8
CAVEY, J. R., RALSTON, S. H., SHEPPARD, P. W., CIANI, B., GALLAGHER, T. R. A., LONG, J. E., SEARLE, M. S. and LAYFIELD, R., 2006. Calcified Tissue International. 78(5), 271-277
HUGHES, C., ELGASIM, M., LAYFIELD, R. and ATIOMO, W., 2006. Human Reproduction. 21(11), 2766-2775
LAYFIELD, R, CAVEY, J R, NAJAT, D, LONG, J, SHEPPARD, P W, RALSTON, S H and SEARLE, M S, 2006. p62 mutations, ubiquitin recognition and Paget's disease of bone. Biochemical Society Transactions. 34(Pt 5), 735-7
HOPKINSON, A., MCINTOSH, R.S., LAYFIELD, R., KEYTE, J., DUA, H.S. and TIGHE, P.J., 2005. Proteomics. 5(7), 1967-1979
CAVEY, J. R., RALSTON, S. H., HOCKING, L. J., SHEPPARD, P. W., CIANI, B., SEARLE, M. S. and LAYFIELD, R., 2005. Journal of Bone and Mineral Research. 20(4), 619-624
LAYFIELD, R., LOWE, J. and BEDFORD, L., 2005. Essays in Biochemistry. VOL 41, 157-171
HOCKING, LYNNE J, LUCAS, GAVIN J A, DAROSZEWSKA, ANNA, CUNDY, TIM, NICHOLSON, GEOFF C, DONATH, JUDIT, WALSH, JOHN P, FINLAYSON, CATRIONA, CAVEY, JAMES R, CIANI, BARBARA, SHEPPARD, PAUL W, SEARLE, MARK S, LAYFIELD, ROBERT and RALSTON, STUART H, 2004. Journal of Bone and Mineral Research. 19(7), 1122-7
LAYFIELD, R., CIANI, B., RALSTON, S. H., HOCKING, L. J., SHEPPARD, P. W., SEARLE, M. S. and CAVEY, J. R., 2004. Biochemical Society Transactions. VOL 32(PART 5), 728-730
LAYFIELD, R. and HOCKING, L. J., 2004. Calcified Tissue International. VOL 75(NUMB 5), 347-357
LAYFIELD, ROBERT, CAVEY, JAMES R and LOWE, JAMES, 2003. Ageing Research Reviews. 2(4), 343-56
ALEXEEV, D., BARLOW, P. N., BURY, S. M., CHARRIER, J.-D., COOPER, A., HADFIELD, D., JAMIESON, C., KELLY, S. M., LAYFIELD, R., MAYER, R. J., MCSPARRON, H., PRICE, N. C., RAMAGE, R., SAWYER, L., STARKMANN, B. A., UHRIN, D., WILKEN, J. and YOUNG, D. W, 2003. ChemBioChem. 4(9), 894-896
CIANI, B., LAYFIELD, R., CAVEY, J. R., SHEPPARD, P. W. and SEARLE, M. S., 2003. Journal of Biological Chemistry. 278(39), 37409-37412
WILKINS, A., MAJED, H., LAYFIELD, R., COMPSTON, A. and CHANDRAN, S., 2003. Journal of Neuroscience. VOL 23(PART 12), 4967-4974
PLATT, G. W., SIMPSON, S. A., LAYFIELD, R. and SEARLE, M. S., 2003. Biochemistry. VOL 42(PART 46), 13762-13771
DAVID, D.C., LAYFIELD, R., SERPELL, L., NARAIN, Y., GOEDERT, M. and SPILLANTINI, M.G, 2002. Journal of Neurochemistry. 83(1), 176-185
LOWE, J, MAYER, J, LANDON, M and LAYFIELD, R, 2001. Ubiquitin and the molecular pathology of neurodegenerative diseases. Advances in Experimental Medicine and Biology. 487, 169-86
LAYFIELD, R, ALBAN, A, MAYER, R J and LOWE, J, 2001. Neuropathology and Applied Neurobiology. 27(3), 171-9
LAYFIELD, R, TOOTH, D, LANDON, M, DAWSON, S, MAYER, J and ALBAN, A, 2001. Proteomics. 1(6), 773-7
KARABULUT, A K, LAYFIELD, R and PRATTEN, M K, 2001. Journal of Anatomy. 198(6), 651-62
LAYFIELD, R., 2001. Medical Hypotheses. VOL 56(PART 3), 395-399
TOFARIS, G. K., LAYFIELD, R. and SPILLANTINI, M. G., 2001. FEBS Letters. VOL 509(NUMBER 1), 22-26
LAM, Y. A., PICKART, C. M., ALBAN, A., LANDON, M., JAMIESON, C., RAMAGE, R., MAYER, R. J. and LAYFIELD, R., 2000. Proceedings of the National Academy of Sciences of the United States of America. VOL 97(PART 18), 9902-9906