糖心原创

Contact

• workRoom A70 Life Sciences Building
  University Park
  Nottingham
  NG7 2RD
  UK
• work0115 9513257
• ian.mellor@nottingham.ac.uk

Biography

Current Position

• Assistant Professor/Lecturer in Molecular Neuroscience, School of Life Sciences, 糖心原创, since 2012.

Previous Positions

• Research Lecturer, Division of Molecular Cell Biology and Biophysics, School of Biology, 糖心原创, 2007-2012.
• Senior Research Fellow, Division of Molecular Toxicology, School of Biology, 糖心原创, 2003 to 2007.
• Chief Experimental Officer, Division of Molecular Toxicology, School of Biology, 糖心原创, 2002 to 2003.
• Senior Experimental Officer, Division of Molecular Toxicology, School of Life and Environmental Sciences, 糖心原创, 1994 to 2002.
• Research Assistant, Department of Life Science, 糖心原创, 1988 to 1994.
• Research Technician, Department of Zoology, 糖心原创, 1986 to 1988.

Teaching Summary

Molecular and Cellular Neuroscience (convenor)

Fundamentals of Neuroscience

Animal Behaviour and Physiology

Higher Skills in the Biological Sciences

Research Projects (BSc and MSci)

Research Summary

My research is focused on several important ion channels of the nervous system including nicotinic acetylcholine receptors (nAChR), ionotropic glutamate receptors (IGR) and voltage-gated sodium… read more

Selected Publications

• NGUM, NEVILLE M., AZIZ, MUHAMMAD Y. A., LATIF, LIAQUE MOHAMMED, WALL, RICHARD J., DUCE, IAN R. and MELLOR, IAN R., 2022. Non-canonical endogenous expression of voltage-gated sodium channel Na(V)1.7 subtype by the TE671 rhabdomyosarcoma cell line JOURNAL OF PHYSIOLOGY-LONDON. 600(10), 2499-2513
• LUCK, VICTORIA L., RICHARDS, DAVID P., SHAIKH, ASHIF Y., FRANZYK, HENRIK and MELLOR, IAN R., 2021. The Effects of Structural Alterations in the Polyamine and Amino Acid Moieties of Philanthotoxins on Nicotinic Acetylcholine Receptor Inhibition in the Locust, Schistocerca gregaria MOLECULES. 26(22),
• PATEL, ROHIT N., RICHARDS, DAVID P., DUCE, IAN R., BIRKETT, MICHAEL A., SATTELLE, DAVID B. and MELLOR, IAN R., 2020. Actions on mammalian and insect nicotinic acetylcholine receptors of harmonine-containing alkaloid extracts from the harlequin ladybird Harmonia axyridis PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY. 166,
• THOMPSON, ANDREW J., VERDIN, PAUL S., BURTON, MARK J., DAVIES, T. G. EMYR, WILLIAMSON, MARTIN S., FIELD, LINDA M., BAINES, RICHARD A., MELLOR, IAN R. and DUCE, IAN R., 2020. The effects of knock-down resistance mutations and alternative splicing on voltage-gated sodium channels in Musca domestica and Drosophila melanogaster INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY. 122,

• View all publications

Current Research

My research is focused on several important ion channels of the nervous system including nicotinic acetylcholine receptors (nAChR), ionotropic glutamate receptors (IGR) and voltage-gated sodium channels and how their functioning is modulated by a variety of naturally occurring animal and plant toxins, drugs and pesticides. These compounds are excellent tools to study the structure and function of ion channels but also represent leads for the development of new drugs and pesticides and help us to understand problems such as pesticide resistance. Specific current interests are polyamine-containing toxins from solitary wasps, alkaloids from ladybirds, toxins from centipedes and pyrethroid insecticides. I am also interested in the development of multi-target directed ligands for Alzheimer's disease, in my case assessing their ability to inhibit NMDA receptor mediated calcium current.

The research is carried out using electrophysiological techniques including patch-clamp of neuronal cultures and cell lines, and voltage-clamp of Xenopus oocytes expressing the channels. Toxin structure-activity and ion channel protein mutation studies have enabled the identification of potent and selective antagonists and potentiators of these ion channels and their mechanisms and sites of action to be determined.

• NGUM, NEVILLE M., AZIZ, MUHAMMAD Y. A., LATIF, LIAQUE MOHAMMED, WALL, RICHARD J., DUCE, IAN R. and MELLOR, IAN R., 2022. Non-canonical endogenous expression of voltage-gated sodium channel Na(V)1.7 subtype by the TE671 rhabdomyosarcoma cell line JOURNAL OF PHYSIOLOGY-LONDON. 600(10), 2499-2513
• AL-NASSER, MARYAM N., MELLOR, IAN R. and CARTER, WAYNE G., 2022. Is L-Glutamate Toxic to Neurons and Thereby Contributes to Neuronal Loss and Neurodegeneration? A Systematic Review BRAIN SCIENCES. 12(5),
• MOHAMAD, MOHAMAD HAIQAL NIZAR, ABU, IZUDDIN FAHMY, FAZEL, MUHAMMAD FATTAH, AGARWAL, RENU, IEZHITSA, IGOR, JULIANA, NORSHAM, MELLOR, IAN R. and FRANZYK, HENRIK, 2021. Neuroprotection Against NMDA-Induced Retinal Damage by Philanthotoxin-343 Involves Reduced Nitrosative Stress FRONTIERS IN PHARMACOLOGY. 12,
• LUCK, VICTORIA L., RICHARDS, DAVID P., SHAIKH, ASHIF Y., FRANZYK, HENRIK and MELLOR, IAN R., 2021. The Effects of Structural Alterations in the Polyamine and Amino Acid Moieties of Philanthotoxins on Nicotinic Acetylcholine Receptor Inhibition in the Locust, Schistocerca gregaria MOLECULES. 26(22),
• FAZEL, MUHAMMAD FATTAH, ABU, IZUDDIN FAHMY, MOHAMAD, MOHAMAD HAIQAL NIZAR, AGARWAL, RENU, IEZHITSA, IGOR, BAKAR, NOR SALMAH, JULIANA, NORSHAM, MELLOR, IAN R. and FRANZYK, HENRIK, 2020. Philanthotoxin-343 attenuates retinal and optic nerve injury, and protects visual function in rats with N-methyl-D-aspartate-induced excitotoxicity PLOS ONE. 15(7),
• PATEL, ROHIT N., RICHARDS, DAVID P., DUCE, IAN R., BIRKETT, MICHAEL A., SATTELLE, DAVID B. and MELLOR, IAN R., 2020. Actions on mammalian and insect nicotinic acetylcholine receptors of harmonine-containing alkaloid extracts from the harlequin ladybird Harmonia axyridis PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY. 166,
• THOMPSON, ANDREW J., VERDIN, PAUL S., BURTON, MARK J., DAVIES, T. G. EMYR, WILLIAMSON, MARTIN S., FIELD, LINDA M., BAINES, RICHARD A., MELLOR, IAN R. and DUCE, IAN R., 2020. The effects of knock-down resistance mutations and alternative splicing on voltage-gated sodium channels in Musca domestica and Drosophila melanogaster INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY. 122,
• KACHEL, HAMID S., FRANZYK, HENRIK and MELLOR, IAN R., 2019. JOURNAL OF MEDICINAL CHEMISTRY. 62(13), 6214-6222
• ROSINI, M, SIMONI, E, CAPORASO, R, BASAGNI, F, CATANZARO, M, ABU, I.F, FAGIANI, F, FUSCO, F, MASUZZO, S, ALBANI, D, LANNI, C, MELLOR, I.R and MINARINI, A, 2019. European Journal of Medicinal Chemistry. 180, 111-120
• KOROMINA, MARIA, FLITTON, MILES, BLOCKLEY, ALIX, MELLOR, IAN R. and KNIGHT, HELEN M., 2019. SCIENTIFIC REPORTS. 9,
• CASEWELL, NICHOLAS R., PETRAS, DANIEL, CARD, DAREN C., SURANSE, VIVEK, MYCHAJLIW, ALEXIS M., RICHARDS, DAVID, KOLUDAROV, IVAN, ALBULESCU, LAURA-OANA, SLAGBOOM, JULIEN, HEMPEL, BENJAMIN-FLORIAN, NGUM, NEVILLE M., KENNERLEY, ROSALIND J., BROCCA, JORGE L., WHITELEY, GARETH, HARRISON, ROBERT A., BOLTON, FIONA M. S., DEBONO, JORDAN, VONK, FREEK J., ALFOLDI, JESSICA, JOHNSON, JEREMY, KARLSSON, ELINOR K., LINDBLAD-TOH, KERSTIN, MELLOR, IAN R., SUSSMUTH, RODERICH D., FRY, BRYAN G., KURUPPU, SANJAYA, HODGSON, WAYNE C., KOOL, JEROEN, CASTOE, TODD A., BARNES, IAN, SUNAGAR, KARTIK, UNDHEIM, EIVIND A. B. and TURVEY, SAMUEL T., 2019. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 116(51), 25745-25755
• KOROMINA, M, FLITTON, M, MELLOR I R and KNIGHT, HM, 2018. The World Journal of Biological Psychiatry. online,
• FURUTANI, SHOGO, IHARA, MAKOTO, LEES, KRISTIN, BUCKINGHAM, STEVEN D., PARTRIDGE, FREDERICK A., DAVID, JONATHAN A., PATEL, ROHIT, WARCHAL, SCOTT, MELLOR, IAN R., MATSUDA, KAZUHIKO and SATTELLE, DAVID B., 2018. INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE. 8(2), 350-360
• SIMONI E, BARTOLINI M, ABU IF, BLOCKLEY A, GOTTI C, BOTTEGONI G, CAPORASO R, BERGAMINI C, ANDRISANO V, CAVALLI A, MELLOR IR, MINARINI A and ROSINI M, 2017. Future medicinal chemistry. 9(10), 953-963
• BERGER, MADELEINE, PUINEAN, ALIN MIREL, RANDALL, EMMA, ZIMMER, CHRISTOPH T., SILVA, WELLINGTON M., BIELZA, PABLO, FIELD, LINDA M., HUGHES, DAVID, MELLOR, IAN, HASSANI-PAK, KEYWAN, SIQUEIRA, HERBERT A. A., WILLIAMSON, MARTIN S. and BASS, CHRIS, 2016. MOLECULAR ECOLOGY. 25(22), 5692-5704
• KACHEL, HAMID S., PATEL, ROHIT N., FRANZYK, HENRIK and MELLOR, IAN R., 2016. SCIENTIFIC REPORTS. 6,
• AMEY JS, O'REILLY AO, BURTON MJ, PUINEAN AM, MELLOR IR, DUCE IR, FIELD LM, WALLACE BA, WILLIAMSON MS and DAVIES TGE, 2015. FEBS letters. 589(5), 598-607
• WALL RJ, FERNANDES A, ROSE M, BELL DR and MELLOR IR, 2015. Environment international. 76, 49-56
• ISLAHUDIN F, TINDALL SM, MELLOR IR, SWIFT K, CHRISTENSEN HEM, FONE KCF, PLEASS RJ, TING K and AVERY SV, 2014. Scientific Reports. 4, 3618
• FRANZYK H, GRZESKOWIAK JW, TIKHONOV DB, JAROSZEWSKI JW and MELLOR IR, 2014. ChemMedChem. 9(8), 1725-31
• KACHEL, HAMID S., FRANZYK, HENRIK, STROMGAARD, KRISTIAN, TIKHONOV, DENIS B. and MELLOR, IAN R., 2014. BIOPHYSICAL JOURNAL. 106(2), 338A-338A
• AMER, ABEER H. A., WALL, RICHARD J., MALLA, SUNIR, SANG, FEI, ABOOBAKER, AZIZ, AVERY, SIMON V., MELLOR, IAN R., ROSE, MARTIN D., ROWLANDS, J. CRAIG, GANT, TIMOTHY W. and BELL, DAVID R., 2014. Toxicology Research. 3(5), 315-323
• PROCOPIOU G, AGGARWAL P, NEWTON AF, RICHARDS D, MELLOR IR, HARBOTTLE G and STOCKMAN RA, 2014. Chemical communications (Cambridge, England). 50(97), 15355-7
• MATSA, E., DIXON, J.E., MEDWAY, C., GEORGIOU, O., PATEL, M.J., MORGAN, K., KEMP, P.J., STANIFORTH, A., MELLOR, I. and DENNING, C., 2014. European Heart Journal. 35(16), 1078-1087
• ROSINI M, SIMONI E, BARTOLINI M, SORIANO E, MARCO-CONTELLES J, ANDRISANO V, MONTI B, WINDISCH M, HUTTER-PAIER B, MCCLYMONT DW, MELLOR IR and BOLOGNESI ML, 2013. ChemMedChem. 8(8), 1276-81
• BARTHELME, A., RICHARDS, D., MELLOR, I.R. and STOCKMAN, R.A., 2013. Chemical Communications. 49(89), 10507-10509
• MCCLYMONT, D.W., HARRIS, J. and MELLOR, I.R., 2012. European Journal of Pharmacology. 686(1-3), 22-31
• WALL, R.J., BELL, D.R., BAZZI, R., FERNANDES, A., ROSE, M., ROWLANDS, J.C. and MELLOR, I.R., 2012. Toxicology. 302(2-3), 140-145
• WALL, R.J., HE, G., DENISON, M.S., CONGIU, C., ONNIS, V., FERNANDES, A., BELL, D.R., ROSE, M., ROWLANDS, J.C., BALBONI, G. and MELLOR, I.R., 2012. Toxicology. 297(1-3), 26-33
• MATSA, E., RAJAMOHAN, D., DICK, E., YOUNG, L., MELLOR, I., STANIFORTH, A. and DENNING, C., 2011. European Heart Journal. 32(8), 952-962
• BURTON, M.J., MELLOR, I.R., DUCE, I.R., DAVIES, T.G.E., FIELD, L.M. and WILLIAMSON, M.S., 2011. Insect Biochemistry and Molecular Biology. 41(9), 723-732
• AMEY, JOANNA S., BURTON, MARK J., O'REILLY, ANDRIAS O., WILLIAMSON, MARTIN S., MELLOR, IAN R., WALLACE, B. A., FIELD, LINDA M. and DAVIES, T. G. E., 2011. Molecular Characterisation of the Voltage-Gated Sodium Channel from Aphids BIOPHYSICAL JOURNAL. 100(3), 425-425
• MELLOR, I.R., 2010. Future Medicinal Chemistry. 2(5), 877-891
• PENG, FANG, MELLOR, IAN R, WILLIAMSON, MARTIN S, DAVIES, T G EMYR, FIELD, LINDA M and USHERWOOD, PETER N R, 2009. Single channel study of deltamethrin interactions with wild-type and mutated rat Na(V)1.2 sodium channels expressed in Xenopus oocytes. Neurotoxicology. 30(3), 358-67
• ROSINI, M., SIMONI, E., BARTOLONI, M., CAVALLI, A., CECCARINI, L., PASCU, N., MCCLYMONT, D.W., TAROZZI, A., BOLOGNESI, M.L., MINARINI, A., TUMIATTI, V., ANDRISANO, V., MELLOR, I.R. and MELCHIORRE, C., 2008. Journal of Medicinal Chemistry. 51(15), 4381-4384
• ANDERSON, D., SELF, T., MELLOR, I.R., GOH, G., HILL, S.J. and DENNING, C., 2007. Molecular Therapy. 15(11), 2027-2036
• USHERWOOD, P N R, DAVIES, T G E, MELLOR, I R, O'REILLY, A O, PENG, F, VAIS, H, KHAMBAY, B P S, FIELD, L M and WILLIAMSON, M S, 2007. FEBS Letters. 581(28), 5485-92
• ANDERSEN, T.F., TIKHONOV, D.B., B脴LCHO, U., BOLSHAKOV, K., NELSON, J.K., PLUTEANU, F., MELLOR, I.R., EGEBJERG, J. and STR脴MGAARD, K., 2006. Journal of Medicinal Chemistry. 49(18), 5414-5423
• OLSEN, C. A., MELLOR, I. R., WELLENDORPH, P., USHERWOOD, P. N. R., WITT, M., FRANZYK, H. and JAROSZEWSKI, J. W., 2006. ChemMedChem. VOL 1(NUMB 3), 303-305
• CLARKSON, C., MELLOR, I.R., LAMBERT, M. and JAROSZEWSKI, J.W., 2006. Planta Medica. 72, 1418-1420
• J脴RGENSEN, M.R., OLSEN, C.A., MELLOR, I.R., USHERWOOD, P.N.R., WITT, M., FRANZYK, H. and JAROSZEWSKI, J.W., 2005. Journal of Medicinal Chemistry. 48(1), 56-70
• BOLSHAKOV, K.V., KIM, K.H., POTAPJEVA, N.N., GMIRO, V.E., TIKHONOV, D.B., USHERWOOD, P.N.R., MELLOR, I.R. and MAGAZANIK, L.G., 2005. Neuropharmacology. 49(2), 144-155
• ZALAT, S., ELBANA, S., RIZZOLI, S., SCHMIDT, J. O. and MELLOR, I. R., 2005. Toxicon. VOL 46(NUMBER 3), 282-290
• MOORE, PAULINE, OGILVIE, JANE, HORRIDGE, ELISABETH, MELLOR, IAN R and CLOTHIER, RICHARD H, 2005. European Journal of Cell Biology. 84(5), 581-92
• STR脴MGAARD, K. and MELLOR, I., 2004. Medicinal Research Reviews. 24(5), 589-620
• TIKHONOV, D.B., MELLOR, I.R. and USHERWOOD, P.N.R., 2004. Biophysical Journal. 87(1), 159-170
• MELLOR, I.R. and USHERWOOD, P.N.R., 2004. Toxicon. 43(5), 493-508
• MELLOR, I.R, OGILVIE, J., PLUTEANU, F., CLOTHIER, R.H., PARKER, T.L., ROSINI, M., MINARINI, A., TUMIATTI, V. and MELCHIORRE, C., 2004. European Journal of Pharmacology. 505(1-3), 37-50
• BRIER, T.J., MELLOR, I.R., TIKHONOV, D.B., NEAGOE, I., SHAO, Z., BRIERLEY, M.J., STR脴MGAARD, K., JAROSZEWSKI, J.W., KROGSGAARD-LARSEN, P. and USHERWOOD, P.N.R., 2003. Molecular Pharmacology. 64(4), 954-964
• MELLOR, I.R., BRIER, T.J., PLUTEANU, F., STR脴MGAARD, K., SAGHYAN, A., ELDURSI, N., BRIERLEY, M.J., ANDERSEN, K., JAROSZEWSKI, J.W., KROGSGAARD-LARSEN, P. and USHERWOOD, P.N.R., 2003. Neuropharmacology. 44(1), 70-80
• OLSEN, C.A., JORGENSEN, M.R., WITT, M., MELLOR, I.R., USHERWOOD, P.N.R., JAROSZEWSKI, J.W. and FRANZYK, H., 2003. European Journal of Organic Chemistry. 17, 3288-3299
• BRIER,T.J., MELLOR,I.R. and USHERWOOD,P.N.R., 2002. Allosteric and steric interactions of polyamines and polyamine-containing toxins with nicotinic acetylcholine receptors. In: MENEZ,A., ed., Perspectives in Molecular Toxinology John Wiley & Sons, Chichester, UK. 281-297
• STROMGAARD, K., MELLOR, I. R., ANDERSEN, K., NEAGOE, I., PLUTEANU, F., USHERWOOD, P. N., KROGSGAARD-LARSEN, P. and JAROSZEWSKI, J. W., 2002. Bioorganic and Medicinal Chemistry Letters. VOL 12(NUMBER 8), 1159-1162
• BIXEL, M.G., WEISE, C., BOLOGNESI, M.L., ROSINI, M., BRIERLY, M.J., MELLOR, I.R., USHERWOOD, P.N.R., MELCHIORRE, C. and HUCHO, F., 2001. Journal of Biological Chemistry. 276(9), 6151-6160
• ZHELIASKOVA, A., NAIDENOVA, S., MARINOV, Y., MELLOR, I. R., USHERWOOD, P. N. R. and PETROV, A. G., 2001. Detection of Heavy Metal Ions (Cd^2^+ and Hg^2^+) by Their Influence on Flexoelectricity of Patch Clamped Lipid Membranes COMPTES RENDUS- ACADEMIE BULGARE DES SCIENCES. VOL 54(PART 12), 53-56
• STROMGAARD, K., BJORNSDOTTIR, I., ANDERSEN, K., BRIERLEY, M., RIZOLI, S., ELDURSI, N., MELLOR, I. R., USHERWOOD, P. N., HANSEN, S. H. and KROGSGAARD-LARSEN, P., 2000. Chirality. VOL 12(PART 2), 93-102
• BIXEL, M.G., KRAUSS, M., LIU, Y., BOLOGNESI, M.L., ROSINI, M., MELLOR, I.S., USHERWOOD, P.N.R., MELCHIORRE, C., NAKANISHI, K. and HUCHO, F., 2000. European Journal of Biochemistry. 267(1), 110-120
• TIKHONOV, D. B., MAGAZANIK, L. G., MELLOR, I. R. and USHERWOOD, P. N. R., 2000. POSSIBLE INFLUENCE OF INTRAMOLECULAR HYDROGEN BONDS ON THE THREE-DIMENSIONAL STRUCTURE OF POLYAMINE AMIDES AND THEIR INTERACTION WITH IONOTROPIC GLUTAMATE RECEPTORS Receptors and Channels. VOL 7(PART 3), 227-236
• STROMGAARD, K., BRIER, T. J., ANDERSEN, K., MELLOR, I. R., SAGHYAN, A., TIKHONOV, D., USHERWOOD, P. N. R., KROGSGAARD-LARSEN, P. and JAROSZEWSKI, J. W., 2000. Journal of Medicinal Chemistry. VOL 43(PART 23), 4526-4533
• MELLOR, I. R., MILLER, B. A., PETROV, A. G., TABAREAN, I. and USHERWOOD, P. N. R., 1999. European Biophysics Journal. VOL 28(NUMBER 4), 346-350
• GRZYWNA, Z. J., SIWY, Z., FULINSKI, A., MELLOR, I. and USHERWOOD, P. N. R., 1999. Chaos in the Potassium Current Through Channels of Locust Muscle Membrane Cellular and Molecular Biology Letters. VOL 4(NUMBER 1), 37-54
• STROMGAARD, K., BRIERLEY, M. J., ANDERSEN, K., SLOK, F. A., MELLOR, I. R., USHERWOOD, P. N., KROGSGAARD-LARSEN, P. and JAROSZEWSKI, J. W., 1999. Journal of Medicinal Chemistry. VOL 42(PART 25), 5224-5234
• ROSINI, M., BUDRIESI, R., BIXEL, M. G., BOLOGNESI, M. L., CHIARINI, A., HUCHO, F., KROGSGAARD-LARSEN, P., MELLOR, I. R., MINARINI, A. and TUMIATTI, V., 1999. Journal of Medicinal Chemistry. VOL 42(PART 25), 5212-5223
• SOLOVIEV, MM, ABUTIDZE, K, MELLOR, I, STREIT, P, GRISHIN, EV, USHERWOOD, PN and BARNARD, EA, 1998. Plasticity of agonist binding sites in hetero-oligomers of the unitary glutamate receptor subunit XenU1 JOURNAL OF NEUROCHEMISTRY. 71(3), 991-1001
• FULINSKI, A, GRZYWNA, Z, MELLOR, I, SIWY, Z and USHERWOOD, PNR, 1998. PHYSICAL REVIEW E. 58(1), 919-924
• TOMLINSON, SIMON R., KIRWIN, SUZANNE, MELLOR, IAN, HARRIS, JOHN, MUNDEY, MANJEET, BRIERLEY, MATTHEW, BELL, DAVID R. and USHERWOOD, PETER N. R., 1997. Interaction of a polyamine amide wasp toxin with cloned and mutant glutamate receptors Biochemical Society Transactions. 25(3), 551S
• MAGAZANIK, LG, BULDAKOVA, SL, SAMOILOVA, MV, GMIRO, VE, MELLOR, IR and USHERWOOD, PNR, 1997. JOURNAL OF PHYSIOLOGY-LONDON. 505(3), 655-663
• SOLOVIEV, M.M., BRIERLEY, M.J., SHAO, Z.Y., MELLOR, I.R., VOLKOVA, T.M., KAMBOJ, R., ISHIMARU, H., SUDAN, H., HARRIS, J., FOLDES, R.L., GRISHIN, E.V., USHERWOOD, P.N.R. and BARNARD, E.A., 1996. Journal of Biological Chemistry. 271, 32572-32579
• GORCZYNSKA, E, HUDDIE, PL, MILLER, BA, MELLOR, IR, VAIS, H, RAMSEY, RL and USHERWOOD, PNR, 1996. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 432(4), 597-606
• SUDAN, H. L., KERRY, C. J., MELLOR, I. R., CHOI, S.-K., HUANG, D., NAKANISHI, K. and USHERWOOD, P. N. R., 1995. The action of philanthotoxin-343 and photolabile analogues on locust (Schistocerca gregaria) muscle Invertebrate Neuroscience. 1(2), 159-172
• SPASSOVA, M, MELLOR, IR, PETROV, AG, BEATTIE, KA, CODD, GA, VAIS, H and USHERWOOD, PNR, 1995. PORES FORMED IN LIPID BILAYERS AND IN NATIVE MEMBRANES BY NODULARIN, A CYANOBACTERIAL TOXIN EUROPEAN BIOPHYSICS JOURNAL. 24(2), 69-76
• USHERWOOD, P N, MELLOR, I, BREEDON, L, HARVEY, R J, BARNARD, E A and DARLISON, M G, 1993. Channels formed by M2 peptides of a putative glutamate receptor subunit of locust. EXS. 63, 241-9
• KERRY, CJ, SUDAN, HL, ABUTIDZE, K, MELLOR, IR, BARNARD, EA and USHERWOOD, PNR, 1993. RECONSTITUTION OF GLUTAMATE-RECEPTOR PROTEINS PURIFIED FROM XENOPUS CENTRAL-NERVOUS-SYSTEM INTO ARTIFICIAL BILAYERS MOLECULAR PHARMACOLOGY. 44(1), 142-152
• AGARWALLA, S, MELLOR, IR, SANSOM, MSP, KARLE, IL, FLIPPENANDERSON, JL, UMA, K, KRISHNA, K, SUKUMAR, M and BALARAM, P, 1992. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 186(1), 8-15
• BALARAM, P, KRISHNA, K, SUKUMAR, M, MELLOR, IR and SANSOM, MSP, 1992. THE PROPERTIES OF ION CHANNELS FORMED BY ZERVAMICINS EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 21(2), 117-128
• SANSOM, MSP, KERR, ID and MELLOR, IR, 1991. ION CHANNELS FORMED BY AMPHIPATHIC HELICAL PEPTIDES - A MOLECULAR MODELING STUDY EUROPEAN BIOPHYSICS JOURNAL. 20(4), 229-240
• KING A T, DAVEY M R, MELLOR I R, MULLIGAN B J and LOWE K C, 1991. SURFACTANT EFFECTS ON YEAST CELLS Enzyme and Microbial Technology. 13(2), 148-153
• SANSOM, MSP and MELLOR, IR, 1990. JOURNAL OF THEORETICAL BIOLOGY. 144(2), 213-223
• MELLOR, IR and SANSOM, MSP, 1990. PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES. 239(1296), 383-400
• MELLOR, IR, THOMAS, DH and SANSOM, MSP, 1988. PROPERTIES OF ION CHANNELS FORMED BY STAPHYLOCOCCUS-AUREUS DELTA-TOXIN BIOCHIMICA ET BIOPHYSICA ACTA. 942(2), 280-294
• MELLOR, IR and SANSOM, MSP, 1988. ION CHANNELS FORMED BY A SHORT CHAIN ALPHA-HELICAL PEPTIDE MASTOPARAN PESTICIDE SCIENCE. 24(1), 87-89
• SANSOM, MSP and MELLOR, IR, 1988. ION CHANNELS IN ARTIFICIAL LIPID BILAYERS NEUROTOX 88. 832, 419-428