ÌÇÐÄÔ­´´

School of Life Sciences
 

Angus Brown

Associate Professor of Neuroscience, Faculty of Medicine & Health Sciences

Contact

  • workRoom E97 The ÌÇÐÄÔ­´´ Medical School
    Queen's Medical Centre
    Nottingham
    NG7 2UH
    UK
  • work0115 82 30173
  • fax0115 82 30142

Research Summary

Energy metabolism in the brain; role of non-glucose substrates, effects of glucose deprivation, role of glycogen.

Selected Publications

  • BROWN, A.M., EVANS, R.D., BLACK, J. and RANSOM, B.R., 2012. Annals of Neurology. 72(3), 406-418
  • EDGAR, J.M., MCLAUGHLIN, M., WERNER, H.B., MCCULLOCH, M.C., BARRIE, J.A., BROWN, A., FAICHNEY, A.B., SNAIDERO, N, NAVE, K.-A. and GRIFFITHS, I.R., 2009. Glia. 57(16), 1815-1824
  • EDGAR, J.M., MCCULLOCH, M.C., MONTAGUE, P., BROWN, A.M., THILEMANN, S., PRATOLA, L., GRUENENFELDER, F.I., GRIFFITHS, I.R. and NAVE, K-A., 2010. EMBO Molecular Medicine. 2(2), 42-50
  • BROWN, A.M., SKAMARAUSKAS, J., LISTER, T., MADJD, A. and RAY, D.E., 2011. Journal of Neurochemistry. 116(6), 996-1004
  • BESWICK-JONES, HANA, HOPPER, AMY and BROWN, ANGUS, 2023. Molecules. 28 523, 1-23
  • HOPPER, AMY and BESWICK-JONES, HANA, 2023. Resilience of compound action potential peaks to high-frequency firing in the mouse optic nerve. Physiological Reports. 11, e15606
  • BESWICK-JONES, HANA and HOPPER, AMY, 2023. Peter Mark Roget: Polymath Extraordinaire. The Journal of the Oughtred Society. 32:1, 34-39
  • HOPPER, AMY and BESWICK-JONES, HANA, 2022. The Nernst equation: using physico-chemical laws to steer novel experimental design. Advances in Physiology Education. 46, 206-210
  • RICH, L and RANSOM, B R, 2022. Energy metabolism in mouse sciatic nerve A fibres during increased energy demand. Metabolites. 12(6), 505
  • HOPPER, AMY and BESWICK-JONES, HANA, 2022. A color-coded graphical guide to the Hodgkin and Huxley papers. Advances in Physiology Education. 46, 580-592
  • POWELL, C L, 2021. A classic experiment revisited: membrane permeability changes during the action potential. Advances in Physiology Education. 45, 178-181
  • POPE, REBECCA and BROWN, ANGUS, 2020. Advances in Physiology Education. 44, 305-308
  • SHORTALL, S E, BROWN, ANGUS, NEWTON-MANN, E and DAWE-LANE, E, 2020. Calbindin deficits may underlie dissociable effects of 5-HT6 and mGlu7 antagonists on glutamate and cognition in a dual-hit neurodevelopmental model for schizophrenia. Molecular Neurobiology. 57, 3439-3457
  • RICH, L, PATRICK, J A and RANSOM, B R, 2020. A method for reducing animal use whilst maintaining statistical power in electrophysiological recordings from rodent nerves. Heliyon. 6, e04143
  • BROWN, ANGUS M., EVANS, RICHARD D., SMITH, PAUL A., RICH, LAURA R. and RANSOM, BRUCE R., 2019. PHYSIOLOGICAL REPORTS. 7(5),
  • BROWN, ANGUS M., 2019. JOURNAL OF PHYSIOLOGY-LONDON. 597(11), 2821-2825
  • ANGUS M BROWN, 2018. Flowcharts to aid student comprehension of Nernst equation calculations Advances in Physiology Education. 42, 260-262
  • RICH LR, 2018. Journal of Physiology. 596.10, 1795-1812
  • BARROS L F, BOLAÑOS J P, BONVENTO G, BOUZIER-SORE A-K, BROWN A M, HIRRLINGER J, KASPAROV S, KIRCHHOFF F, MURPHY A N, PELLERIN L and ROBINSON M B, 2018. Current technical approaches to brain energy metabolism Glia. 66, 1138-1159
  • BARROS L F and BROWN A M, 2018. Glia in brain energy metabolism: A perspective Glia. 66, 1134-1137
  • SAWYER JE, HENNEBRY JE, REVILL A and BROWN AM, 2017. Advances in physiology education. 41(2), 231-238
  • CASES, M, LLOBET, A, TERNI, B, DE ARANDA, IG, BLANCH, M, REVILL, A, BROWN, A, BLASI, J, SOLSONA, C and SOLSONA, C, 2017. eNeuro. 4(4)(e0051-17), 1-16
  • BROWN, A, 2017. Neurochemical Research. 42(9), 2456–2467
  • RICH L and BROWN AM, 2016. The Neuroscientist. 23(4), 356-363
  • ROCKLIFFE, A.M., EBLING, F.J.P. and BROWN, A.M., 2016. The role of nervous system glycogen during hypoglycemia Journal of Endocrine Disorders. 3(1), 1020
  • BROWN AM and RANSOM BR, 2015. Metabolic brain disease. 30(1), 233-9
  • FRYER KL and BROWN AM, 2015. Metabolic brain disease. 30(1), 299-306
  • SAWBRIDGE, JL, QURESHI, HK, BOYD, MJ and BROWN, AM, 2014. Advances in Physiology Education. 38(3), 239-245
  • CHAMBERS TW, DALY TP, HOCKLEY A and BROWN AM, 2014. Frontiers in neuroscience. 8, 378
  • BROWN AM and HAMANN M, 2014. Frontiers in neuroanatomy. 8, 73
  • YANG X, HAMNER MA, BROWN AM, EVANS RD, YE Z, CHEN S and RANSOM BR, 2014. Annals of neurology. 75(4), 492-507
  • LAMBERT R J W, MYTILINAIOS I, MAITLAND L & BROWN A M., 2012. Monte Carlo simulation of parameter confidence intervals for non-linear regression analysis of biological data using Microsoft Excel. Computers Methods and Programs in Biomedicine. 107, 155-163
  • BROWN, A.M., EVANS, R.D., BLACK, J. and RANSOM, B.R., 2012. Annals of Neurology. 72(3), 406-418
  • BROWN, A.M., SKAMARAUSKAS, J., LISTER, T., MADJD, A. and RAY, D.E., 2011. Journal of Neurochemistry. 116(6), 996-1004
  • JONES, CA, BROWN, AM, AUER, DP and FONE, KCF, 2011. Psychopharmacology. 214(1), 269-283
  • BROWN, AM, 2010. Computer Methods And Programs In Biomedicine. 98(1), 76-82
  • EVANS, RD, WESTON, DA, MCLAUGHLIN, M and BROWN, AM, 2010. Journal Of Neuroscience Methods. 188(1), 174-178
  • EDGAR, J.M., MCCULLOCH, M.C., MONTAGUE, P., BROWN, A.M., THILEMANN, S., PRATOLA, L., GRUENENFELDER, F.I., GRIFFITHS, I.R. and NAVE, K-A., 2010. EMBO Molecular Medicine. 2(2), 42-50
  • JAMES, EL, PEACOCK, VAH, EBLING, FJP and BROWN, AM, 2010. Anatomical Science International. 85(4), 214-223
  • EDGAR, J.M., MCLAUGHLIN, M., WERNER, H.B., MCCULLOCH, M.C., BARRIE, J.A., BROWN, A., FAICHNEY, A.B., SNAIDERO, N, NAVE, K.-A. and GRIFFITHS, I.R., 2009. Glia. 57(16), 1815-1824
  • WALLS, AB, SICKMANN, HM, BROWN, A, BOUMAN, SD, RANSOM, B, SCHOUSBOE, A and WAAGEPETERSEN, HS, 2008. Journal Of Neurochemistry. 105(4), 1462-1470
  • BROWN, AM and RANSOM, BR, 2007. Glia. 55(12), 1263-1271
  • MEAKIN, PJ, FOWLER, MJ, RATHBONE, AJ, ALLEN, LM, RANSOM, BR, RAY, DE and BROWN, AM, 2007. Journal Of Cerebral Blood Flow And Metabolism. 27(1), 86-99
  • ALLEN, L, ANDERSON, S, WENDER, R, MEAKIN, P, RANSOM, BR, RAY, DE and BROWN, AM, 2006. Journal Of Neurophysiology. 95(3), 1917-1925
  • BROWN, AM, 2006. Computer Methods And Programs In Biomedicine. 82(1), 51-57
  • BROWN, AM, SICKMANN, HM, FOSGERAU, K, LUND, TM, SHOUSBOE, A, WAAGEPETERSEN, HS and RANSOM, BR, 2005. Journal of Neuroscience Research. 79, 74-80
  • BROWN, AM, 2005. Computer Methods And Programs In Biomedicine. 79(1), 89-95
  • TEKKOK, SB, BROWN, AM, WESTENBROEK, R, PELLERIN, L and RANSOM, BR, 2005. Journal Of Neuroscience Research. 81(5), 644-652
  • BROWN, A.M, 2004. Journal of Neurochemistry. 89(3), 537-552
  • BROWN, ANGUS M, BALTAN TEKKöK, SELVA and RANSOM, BRUCE R, 2004. Neurochemistry International. 45(4), 529-36
  • BYERS, MARGARET R, MAEDA, TAKEYASU, BROWN, ANGUS M and WESTENBROEK, RUTH E, 2004. Microscopy Research and Technique. 65(6), 295-307
  • PRIOR, MJW, BROWN, AM, MAVROUDIS, G, LISTER, T and RAY, DE, 2004. Magnetic Resonance Materials In Physics Biology And Medicine. 17(3-6), 125-132
  • BROWN, A.M., TEKKÖK, S.B. and RANSOM, B.R, 2003. Journal of Physiology. 549(2), 501-512
  • BROWN, A. M., 2003. Computer Methods and Programs in Biomedicine. VOL 71(NUMBER 1), 25-31
  • RANSOM, BRUCE R and BROWN, ANGUS M, 2003. Neuron. 40(1), 2-4
  • TEKKOK, S. B., BROWN, A. M. and RANSOM, B. R., 2003. Journal of Cerebral Blood Flow and Metabolism. VOL 23(PART 11), 1340-1347
  • MACVICAR, BRIAN A, FEIGHAN, DENISE, BROWN, ANGUS and RANSOM, BRUCE, 2002. Glia. 37(2), 114-23
  • BROWN, A M, TEKKöK, S B and RANSOM, B R, 2002. Hypoglycemia and white matter: pathophysiology of axon injury and role of glycogen. Diabetes Nutrition and Metabolism. 15(5), 290-3; discussion 293-4
  • BROWN, A. M. and RANSOM, B. R., 2002. Journal of Neurophysiology. VOL 88(PART 3), 1302-1307
  • CHEN, CHUNLING, BHARUCHA, VANDANA, CHEN, YUAN, WESTENBROEK, RUTH E, BROWN, ANGUS, MALHOTRA, JYOTI DHAR, JONES, DOROTHY, AVERY, CHRISTY, GILLESPIE, PATRICK J, KAZEN-GILLESPIE, KRISTIN A, KAZARINOVA-NOYES, KATIE, SHRAGER, PETER, SAUNDERS, THOMAS L, MACDONALD, ROBERT L, RANSOM, BRUCE R, SCHEUER, TODD, CATTERALL, WILLIAM A and ISOM, LORI L, 2002. Proceedings of the National Academy of Sciences of the United States of America. 99(26), 17072-7
  • BROWN, A.M., WENDER, R. and RANSOM, B.R, 2001. Ionic mechanisms of aglycemic axon injury in mammalian central white matter. Journal of Cerebral Blood Flow and Metabolism. 21(4), 385-395
  • BROWN, A. M., 2001. Computer Methods and Programs in Biomedicine. VOL 65(NUMBER 3), 191 - 200
  • BROWN, A. M., WENDER, R. and RANSOM, B. R., 2001. Journal of Neuroscience Research. VOL 66(NUMB 5), 839-843
  • BROWN, A M, WESTENBROEK, R E, CATTERALL, W A and RANSOM, B R, 2001. Axonal L-type Ca2+ channels and anoxic injury in rat CNS white matter. Journal of Neurophysiology. 85(2), 900-11
  • WENDER, R, BROWN, A M, FERN, R, SWANSON, R A, FARRELL, K and RANSOM, B R, 2000. Astrocytic glycogen influences axon function and survival during glucose deprivation in central white matter. Journal of Neuroscience. 20(18), 6804-10
  • BROWN, A M, 2000. Computer Methods and Programs in Biomedicine. 63(1), 47-54
  • BROWN, A M, 1999. Computer Methods and Programs in Biomedicine. 58(2), 181-90
  • BROWN, A M, FERN, R, JARVINEN, J P, KAILA, K and RANSOM, B R, 1998. NeuroReport. 9(9), 1997-2000

School of Life Sciences

ÌÇÐÄÔ­´´
Medical School
Queen's Medical Centre
Nottingham NG7 2UH

e: life-sciences@nottingham.ac.uk
t: +44 (0)115 823 0141
f: +44 (0)115 823 0142