糖心原创

Contact

• workRoom B107 Life Sciences Building
  University Park
  Nottingham
  NG7 2RD
  UK
• work0115 82 30734
• paddy.tighe@nottingham.ac.uk

Biography

My lab has interests in rare autoinflammatory conditions and systemic autoimmune diseases and I has spent many years investigating the molecular mechanisms associated with defects in the TNFR1 receptor which give rise to TNF-receptor-associated periodic syndrome (TRAPS). Over this time I have developed a number of methodologies for high-thoughput, high-content screening to enable wide-scale analysis of intrasignalling pathways within cells and serum-based assays (autoantibodies, pathogen-specific antibodies and other serum markers). This has lead to successful MRC applications in the area of drug repurposing in the context of the autoinflammatory diseases TRAPS, and subsequently to funding and collaborations applying these technologies for cancer early diagnosis (autoantibody detection) and alternatives to TMA tumour staining (tumour antigen detection), analysis and drug repurposing in systemic lupus erythematosus and ongoing projects in immune response surveillance in relation to influenza vaccine administration and a range of conditions including rheumatoid arthritis, Myasthenia gravis, H. pylori and C. difficile infections. I have current collaborations with both optical and electronics engineers in terms of label-free immunosensing methodologies.

Expertise Summary

I am an immunologist with many years experience of molecular cloning technologies, Molecular Immunology, T cell receptor analysis, DNA fragment analysis, fluorescent methods and real-time quantification, microarray and macroarray printing capabilities; automated colony picking; liquid handling robotics; lab-on-a-chip technologies; microarray probe generation and quality control; automated stations for moderate/high-throughput serological analysis etc.

Teaching Summary

I am interested in distance learning technologies and virtual learning environments and how to enhance the interaction of students with materials on VLEs. I am a keen supporter of mixed media… read more

Research Summary

I am currently involved in projects examining the potential of detecting autoantibodies which develop against tumour associated antigens(TAAs) as a route towards early diagnosis in relation to a… read more

Selected Publications

• VOYSEY, M., COSTA CLEMENS, S. A., MADHI, S. A., WECKX, L. Y., FOLEGATTI, P. M., ALEY, P. K., ANGUS, B., BAILLIE, V. L., BARNABAS, S. L., BHORAT, Q. E., BIBI, S., BRINER, C., CICCONI, P., CLUTTERBUCK, E. A., COLLINS, A. M., CUTLAND, C. L., DARTON, T. C., DHEDA, K., DOLD, C., DUNCAN, C. J. A., EMARY, K. R. W., EWER, K. J., FLAXMAN, A., FAIRLIE, L., FAUST, S. N., FENG, S., FERREIRA, D. M., FINN, A., GALIZA, E., GOODMAN, A. L., GREEN, C. M., GREEN, C. A., GREENLAND, M., HILL, C., HILL, H. C., HIRSCH, I., IZU, A., JENKIN, D., JOE, C. C. D., KERRIDGE, S., KOEN, A., KWATRA, G., LAZARUS, R., LIBRI, V., LILLIE, P. J., MARCHEVSKY, N. G., MARSHALL, R. P., MENDES, A. V. A., MILAN, E. P., MINASSIAN, A. M., MCGREGOR, A., MUJADIDI, Y. F., NANA, A., PADAYACHEE, S. D., PHILLIPS, D. J., PITTELLA, A., PLESTED, E., POLLOCK, K. M., RAMASAMY, M. N., RITCHIE, A. J., ROBINSON, H., SCHWARZBOLD, A. V., SMITH, A., SONG, R., SNAPE, M. D., SPRINZ, E., SUTHERLAND, R. K., THOMSON, E. C., TOROK, M. E., TOSHNER, M., TURNER, D. P. J., VEKEMANS, J., VILLAFANA, T. L., WHITE, T., WILLIAMS, C. J., DOUGLAS, A. D., HILL, A. V. S., LAMBE, T., GILBERT, S. C., POLLARD, A. J. and OXFORD, COVID VACCINE TRIAL GROUP, 2021. Lancet. 397(10277), 881-891
• VOYSEY, M., CLEMENS, S. A. C., MADHI, S. A., WECKX, L. Y., FOLEGATTI, P. M., ALEY, P. K., ANGUS, B., BAILLIE, V. L., BARNABAS, S. L., BHORAT, Q. E., BIBI, S., BRINER, C., CICCONI, P., COLLINS, A. M., COLIN-JONES, R., CUTLAND, C. L., DARTON, T. C., DHEDA, K., DUNCAN, C. J. A., EMARY, K. R. W., EWER, K. J., FAIRLIE, L., FAUST, S. N., FENG, S., FERREIRA, D. M., FINN, A., GOODMAN, A. L., GREEN, C. M., GREEN, C. A., HEATH, P. T., HILL, C., HILL, H., HIRSCH, I., HODGSON, S. H. C., IZU, A., JACKSON, S., JENKIN, D., JOE, C. C. D., KERRIDGE, S., KOEN, A., KWATRA, G., LAZARUS, R., LAWRIE, A. M., LELLIOTT, A., LIBRI, V., LILLIE, P. J., MALLORY, R., MENDES, A. V. A., MILAN, E. P., MINASSIAN, A. M., MCGREGOR, A., MORRISON, H., MUJADIDI, Y. F., NANA, A., O'REILLY, P. J., PADAYACHEE, S. D., PITTELLA, A., PLESTED, E., POLLOCK, K. M., RAMASAMY, M. N., RHEAD, S., SCHWARZBOLD, A. V., SINGH, N., SMITH, A., SONG, R., SNAPE, M. D., SPRINZ, E., SUTHERLAND, R. K., TARRANT, R., THOMSON, E. C., TOROK, M. E., TOSHNER, M., TURNER, D. P. J., VEKEMANS, J., VILLAFANA, T. L., WATSON, M. E. E., WILLIAMS, C. J., DOUGLAS, A. D., HILL, A. V. S., LAMBE, T., GILBERT, S. C., POLLARD, A. J. and OXFORD, COVID VACCINE TRIAL GROUP, 2021. Lancet. 397(10269), 99-111
• HAMED, A., TODD, I., TIGHE, P. J., POWELL, R. J., HARRISON, T. and FAIRCLOUGH, L. C., 2021. J Immunol Methods. 492, 112999
• ALLEN, C. M., RAMSAMY, S., TARR, A. W., TIGHE, P. J., IRVING, W. L., TANASESCU, R. and EVANS, J. R., 2021. Ann Neurol. 90(2), 315-318

• View all publications

I am interested in distance learning technologies and virtual learning environments and how to enhance the interaction of students with materials on VLEs. I am a keen supporter of mixed media podcasting and am involved in University funded video/screen podcasting developments.

I teach on multiple modules and courses across the Life Sciences and Medical degrees, and convene a popular undergraduate module "Infection and Immunity" for yr 2 undergraduates in the Life sciences. I convene other modules, including "Autoimmunity" and "Therapeutic Immunology" which are available to post-graduate taught-course (Masters degree) students.

Current Research

I am currently involved in projects examining the potential of detecting autoantibodies which develop against tumour associated antigens(TAAs) as a route towards early diagnosis in relation to a number of common solid cancers. These investigations are aimed to enhance early rapid diagnosis and stratification of patients who may have cancer.

Thes methods originated in early work performed on screening methods for autoantibody detection in systemic autoimmune diseases .

My group also has interests in rare immune-mediated conditions, such as the the rare autoinflammatory diseases and common variable immunodeficiences.

Past Research

Autoimmunity (Autoimmune uveitis, SLE) peptide immunotherapeutics, Rare autoinflammatory disease mechanisms (related to TNF receptor-associated periodic syndrome (TRAPS) and intracellular signaling in relation to inflammatory pathway signalling

Future Research

My group is developing novel detection methods (including the use of nanobodies, peptide libraries and microfluidics approaches to generate comprehensive diagnostic testing methods for autoantibodies and serum biomarkers

• VEDHARA, K, AYLING, K, JIA, R, FAIRCLOUGH, L, MORLING, JR, BLAKE, H, CORNER, J, DENNING, C, BOLTON, C, JACKSON, H, COUPLAND, C and TIGHE, P, 2022. The Journal of Infectious Diseases. 225(12), 2137-2141
• TURNBULL, JAMES, JHA, RAKESH, ORTORI, CATHERINE A, LUNT, ELEANOR, TIGHE, PATRICK J, IRVING, WILLIAM L, GOHIR, SAMEER A, KIM, DONG-HYUN, VALDES, ANA M, TARR, ALEXANDER W, BARRETT, DAVID A and CHAPMAN, VICTORIA, 2022. The Journal of Infectious Diseases.
• SCURR, M. J., ZELEK, W. M., LIPPIATT, G., SOMERVILLE, M., BURNELL, S. E. A., CAPITANI, L., DAVIES, K., LAWTON, H., TOZER, T., REES, T., ROBERTS, K., EVANS, M., JACKSON, A., YOUNG, C., FAIRCLOUGH, L., TIGHE, P., WILLS, M., WESTWELL, A. D., MORGAN, B. P., GALLIMORE, A. and GODKIN, A., 2022. Immunology. 165(2), 250-259
• GALOZZI, P., NEGM, O., BINDOLI, S., TIGHE, P., SFRISO, P. and PUNZI, L., 2022. Int J Mol Sci. 23(3),
• CHAPPELL, H., PATEL, R., DRIESSENS, C., TARR, A. W., IRVING, W. L., TIGHE, P. J., JACKSON, H. J., HARVEY-COWLISHAW, T., MILLS, L., SHAUNAK, M., GBESEMETE, D., LEAHY, A., LUCAS, J. S., FAUST, S. N. and DE GRAAF, H., 2022. J Infect. 84(1), 31-39
• ASTBURY, S., REYNOLDS, C. J., BUTLER, D. K., MUNOZ-SANDOVAL, D. C., LIN, K. M., PIEPER, F. P., OTTER, A., KOURAKI, A., CUSIN, L., NIGHTINGALE, J., VIJAY, A., CRAXFORD, S., AITHAL, G. P., TIGHE, P. J., GIBBONS, J. M., PADE, C., JOY, G., MAINI, M., CHAIN, B., SEMPER, A., BROOKS, T., OLLIVERE, B. J., MCKNIGHT, A., NOURSADEGHI, M., TREIBEL, T. A., MANISTY, C., MOON, J. C., C. OVIDSORTIUM INVESTIGATORS, VALDES, A. M., BOYTON, R. J. and ALTMANN, D. M., 2022. Immunology.
• VEDHARA, K., AYLING, K., JIA, R., FAIRCLOUGH, L., MORLING, J. R., BALL, J. K., KNIGHT, H., BLAKE, H., CORNER, J., DENNING, C., BOLTON, K., JACKSON, H., COUPLAND, C. and TIGHE, P., 2022. J Infect Dis.
• VEDHARA, K., AYLING, K., JIA, R., FAIRCLOUGH, L., MORLING, J. R., BALL, J. K., KNIGHT, H., BLAKE, H., CORNER, J., DENNING, C., BOLTON, K., JACKSON, H., COUPLAND, C. and TIGHE, P., 2022. J Infect Dis.
• VOYSEY, M., COSTA CLEMENS, S. A., MADHI, S. A., WECKX, L. Y., FOLEGATTI, P. M., ALEY, P. K., ANGUS, B., BAILLIE, V. L., BARNABAS, S. L., BHORAT, Q. E., BIBI, S., BRINER, C., CICCONI, P., CLUTTERBUCK, E. A., COLLINS, A. M., CUTLAND, C. L., DARTON, T. C., DHEDA, K., DOLD, C., DUNCAN, C. J. A., EMARY, K. R. W., EWER, K. J., FLAXMAN, A., FAIRLIE, L., FAUST, S. N., FENG, S., FERREIRA, D. M., FINN, A., GALIZA, E., GOODMAN, A. L., GREEN, C. M., GREEN, C. A., GREENLAND, M., HILL, C., HILL, H. C., HIRSCH, I., IZU, A., JENKIN, D., JOE, C. C. D., KERRIDGE, S., KOEN, A., KWATRA, G., LAZARUS, R., LIBRI, V., LILLIE, P. J., MARCHEVSKY, N. G., MARSHALL, R. P., MENDES, A. V. A., MILAN, E. P., MINASSIAN, A. M., MCGREGOR, A., MUJADIDI, Y. F., NANA, A., PADAYACHEE, S. D., PHILLIPS, D. J., PITTELLA, A., PLESTED, E., POLLOCK, K. M., RAMASAMY, M. N., RITCHIE, A. J., ROBINSON, H., SCHWARZBOLD, A. V., SMITH, A., SONG, R., SNAPE, M. D., SPRINZ, E., SUTHERLAND, R. K., THOMSON, E. C., TOROK, M. E., TOSHNER, M., TURNER, D. P. J., VEKEMANS, J., VILLAFANA, T. L., WHITE, T., WILLIAMS, C. J., DOUGLAS, A. D., HILL, A. V. S., LAMBE, T., GILBERT, S. C., POLLARD, A. J. and OXFORD, COVID VACCINE TRIAL GROUP, 2021. Lancet. 397(10277), 881-891
• VOYSEY, M., CLEMENS, S. A. C., MADHI, S. A., WECKX, L. Y., FOLEGATTI, P. M., ALEY, P. K., ANGUS, B., BAILLIE, V. L., BARNABAS, S. L., BHORAT, Q. E., BIBI, S., BRINER, C., CICCONI, P., COLLINS, A. M., COLIN-JONES, R., CUTLAND, C. L., DARTON, T. C., DHEDA, K., DUNCAN, C. J. A., EMARY, K. R. W., EWER, K. J., FAIRLIE, L., FAUST, S. N., FENG, S., FERREIRA, D. M., FINN, A., GOODMAN, A. L., GREEN, C. M., GREEN, C. A., HEATH, P. T., HILL, C., HILL, H., HIRSCH, I., HODGSON, S. H. C., IZU, A., JACKSON, S., JENKIN, D., JOE, C. C. D., KERRIDGE, S., KOEN, A., KWATRA, G., LAZARUS, R., LAWRIE, A. M., LELLIOTT, A., LIBRI, V., LILLIE, P. J., MALLORY, R., MENDES, A. V. A., MILAN, E. P., MINASSIAN, A. M., MCGREGOR, A., MORRISON, H., MUJADIDI, Y. F., NANA, A., O'REILLY, P. J., PADAYACHEE, S. D., PITTELLA, A., PLESTED, E., POLLOCK, K. M., RAMASAMY, M. N., RHEAD, S., SCHWARZBOLD, A. V., SINGH, N., SMITH, A., SONG, R., SNAPE, M. D., SPRINZ, E., SUTHERLAND, R. K., TARRANT, R., THOMSON, E. C., TOROK, M. E., TOSHNER, M., TURNER, D. P. J., VEKEMANS, J., VILLAFANA, T. L., WATSON, M. E. E., WILLIAMS, C. J., DOUGLAS, A. D., HILL, A. V. S., LAMBE, T., GILBERT, S. C., POLLARD, A. J. and OXFORD, COVID VACCINE TRIAL GROUP, 2021. Lancet. 397(10269), 99-111
• VALDES, ANA M., MOON, JAMES C., VIJAY, AMRITA, CHATURVEDI, NISH, NORRISH, ALAN, IKRAM, ADEEL, CRAXFORD, SIMON, CUSIN, LOLA M. L., NIGHTINGALE, JESSICA, SEMPER, AMANDA, BROOKS, TIMOTHY, MCKNIGHT, AINE, KURDI, HIBBA, MENNI, CRISTINA, TIGHE, PATRICK, NOURSADEGHI, MAHDAD, AITHAL, GURUPRASAD, TREIBEL, THOMAS A., OLLIVERE, BENJAMIN J. and MANISTY, CHARLOTTE, 2021. EClinicalMedicine. 100835
• HAMED, A., TODD, I., TIGHE, P. J., POWELL, R. J., HARRISON, T. and FAIRCLOUGH, L. C., 2021. J Immunol Methods. 492, 112999
• ALLEN, C. M., RAMSAMY, S., TARR, A. W., TIGHE, P. J., IRVING, W. L., TANASESCU, R. and EVANS, J. R., 2021. Ann Neurol. 90(2), 315-318
• ALBOGAMI, S., TODD, I., NEGM, O., FAIRCLOUGH, L. C. and TIGHE, P. J., 2021. Immunology.
• URBANOWICZ, RICHARD A., TSOLERIDIS, THEOCHARIS, JACKSON, HANNAH J., CUSIN, LOLA, DUNCAN, JOSHUA D., CHAPPELL, JOSEPH G., TARR, ALEXANDER W., NIGHTINGALE, JESSICA, NORRISH, ALAN R., IKRAM, ADEEL, MARSON, BEN, CRAXFORD, SIMON J., KELLY, ANTHONY, AITHAL, GURUPRASAD P., VIJAY, AMRITA, TIGHE, PATRICK J., BALL, JONATHAN K., VALDES, ANA M. and OLLIVERE, BENJAMIN J., 2021. SCIENCE TRANSLATIONAL MEDICINE. 13(609),
• TODD, I., THOMAS, R. E., WATT, B. D., SUTHERLAND, L., AFRIYIE-ASANTE, A., DEB, B., JOSEPH, B., TIGHE, P. J., LANYON, P. and FAIRCLOUGH, L. C., 2020. Rheumatology (Oxford). 59(12), 3980-3982
• TIGHE, PATRICK J., URBANOWICZ, RICHARD A., FAIRCLOUGH, C. LUCY, MCCLURE, C. PATRICK, THOMSON, BRIAN J., GOMEZ, NANCY, CHAPPELL, JOSEPH G., TSOLERIDIS, THEOCHARIS, LOOSE, MATTHEW, CARLILE, MATTHEW, MOORE, CHRISTOPHER, HOLMES, NADINE, SANG, FEI, HRUSHIKESH, DIVYATEJA, CLARK, GEMMA, TEMPERTON, NIGEL, BROOKS, TIM, BALL, JONATHAN K., IRVING, WILLIAM L. and TARR, ALEXANDER W., 2020. medRxiv. 2020.08.22.20176834
• CHEN, I. L., TODD, I., TIGHE, P. J. and FAIRCLOUGH, L. C., 2020. Arch Toxicol. 94(6), 2097-2112
• LIU, YI-CHIA, HUSSAIN, FARAH, NEGM, OLA, PAIVA, ANA CAROLINA, HALLIDAY, NIGEL, DUBERN, JEAN-FREDERIC, SINGH, SONALI, MUNTAKA, SIRINA, WHELDON, LEE, LUCKETT, JENI, TIGHE, PADDY, BOSQUILLON, CYNTHIA, WILLIAMS, PAUL, CAMARA, MIGUEL and MARTINEZ-POMARES, LUISA, 2019. FRONTIERS IN MICROBIOLOGY. 10,
• BYRNE, RACHEL, TODD, IAN, TIGHE, PATRICK J and FAIRCLOUGH, LUCY C, 2019. Immunology letters. 214, 8-15
• TARBIAH, NESRIN, TODD, IAN, TIGHE, PATRICK J and FAIRCLOUGH, LUCY C, 2019. Basic & clinical pharmacology & toxicology.
• NEGM, O. H., SINGH, S., ABDULJABBAR, W., HAMED, M. R., RADFORD, P., MCDERMOTT, E. M., DREWE, E., FAIRCLOUGH, L., TODD, I and TIGHE, P. J., 2019. CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 197(3), 352-360
• AYLING K, FAIRCLOUGH L, TIGHE P, TODD I, HALLIDAY V, GARIBALDI J, ROYAL S, HAMED A, BUCHANAN H and VEDHARA K, 2018. Brain, behavior, and immunity. 314-23
• SHORTALL SE, NEGM OH, FOWLER M, FAIRCLOUGH LC, TIGHE PJ, WIGMORE PM and KING MV, 2018. Molecular neurobiology. (In Press.)
• LIU, YI-CHIA, HUSSAIN, FARAH, NEGM, OLA, PAVIA, ANA, HALLIDAY, NIGEL, DUBERN, JEAN-FREDERIC, SINGH, SONALI, MUNTAKA, SIRINA, WHELDON, LEE, LUCKETT, JENI, TIGHE, PADDY, BOSQUILLON, CYNTHIA, WILLIAMS, PAUL, CAMARA, MIGUEL and MARTINEZ-POMARES, LUISA, 2018. Data_Sheet_1_Contribution of the Alkylquinolone Quorum-Sensing System to the Interaction of Pseudomonas aeruginosa With Bronchial Epithelial Cells.PDF Figshare.
• LIU, YI-CHIA, HUSSAIN, FARAH, NEGM, OLA, PAVIA, ANA, HALLIDAY, NIGEL, DUBERN, JEAN-FREDERIC, SINGH, SONALI, MUNTAKA, SIRINA, WHELDON, LEE, LUCKETT, JENI, TIGHE, PADDY, BOSQUILLON, CYNTHIA, WILLIAMS, PAUL, CAMARA, MIGUEL and MARTINEZ-POMARES, LUISA, 2018. Data_Sheet_2_Contribution of the Alkylquinolone Quorum-Sensing System to the Interaction of Pseudomonas aeruginosa With Bronchial Epithelial Cells.PDF Figshare.
• LIU, YI-CHIA, HUSSAIN, FARAH, NEGM, OLA, PAVIA, ANA, HALLIDAY, NIGEL, DUBERN, JEAN-FREDERIC, SINGH, SONALI, MUNTAKA, SIRINA, WHELDON, LEE, LUCKETT, JENI, TIGHE, PADDY, BOSQUILLON, CYNTHIA, WILLIAMS, PAUL, CAMARA, MIGUEL and MARTINEZ-POMARES, LUISA, 2018. FRONTIERS IN MICROBIOLOGY. 9,
• TUBBY C, NEGM OH, HARRISON T, TIGHE PJ, TODD I and FAIRCLOUGH LC, 2017. The Journal of asthma : official journal of the Association for the Care of Asthma. 54(5), 456-466
• AYLING K, BOWDEN T, TIGHE P, TODD I, DILNOT EM, NEGM OH, FAIRCLOUGH L and VEDHARA K, 2017. Brain, behavior, and immunity. 59, 62-66
• TODD I, NEGM OH, REPS J, RADFORD P, FIGUEREDO G, MCDERMOTT EM, DREWE E, POWELL RJ, BAINBRIDGE S, HAMED M, CROUCH S, GARIBALDI J, ST-GALLAY S, FAIRCLOUGH LC and TIGHE PJ, 2017. Pharmacological Research.
• F SALAZAR, L HALL, OH NEGM, D AWUAH, P TIGHE, F SHAKIB and AM GHAEMMAGHAMI, 2016. J Allergy Clin Immunol. 137(6), 1841-1851
• NEGM, O. H., MUFTAH, A. A., ALESKANDARANY, M. A., HAMED, M. R., AHMAD, D. A., NOLAN, C. C., DIEZ-RODRIGUEZ, M., TIGHE, P. J., ELLIS, I. O., RAKHA, E. A. and GREEN, A. R., 2016. Breast cancer research and treatment. 155(1), 25-35
• ALESKANDARANY, M. A., AGARWAL, D., NEGM, O. H., BALL, G., ELMOUNA, A., ASHANKYTY, I., NUGLOZEH, E., FAZALUDEEN, M. F., DIEZ-RODRIGUEZ, M., NOLAN, C. C., TIGHE, P. J., GREEN, A. R., ELLIS, I. O. and RAKHA, E. A., 2016. Breast cancer research and treatment.
• SENTHOORAN SELVARAJAH, IAN TODD, PATRICK TIGHE, MICHELLE JOHN, CHARLOTTE E. BOLTON, TIM HARRISON and LUCY FAIRCLOUGH, 2016. Multiple circulating cytokines are co-elevated in chronic obstructive pulmonary disease. (In Press.)
• SALAZAR, F., HALL, L., NEGM, O. H., AWUAH, D., TIGHE, P. J., SHAKIB, F. and GHAEMMAGHAMI, A. M., 2016. J Allergy Clin Immunol. 137(6), 1841-1851 e2
• MOZ S, BASSO D, BOZZATO D, GALOZZI P, NAVAGLIA F, NEGM OH, ARRIGONI G, ZAMBON CF, PADOAN A, TIGHE P, TODD I, FRANCHIN C, PEDRAZZOLI S, PUNZI L and PLEBANI M, 2016. Oncotarget. (In Press.)
• ABDULJABBAR R, AL-KAABI MM, NEGM OH, JERJEES D, MUFTAH AA, MUKHERJEE A, LAI CF, BULUWELA L, ALI S, TIGHE PJ, GREEN A, ELLIS I and RAKHA E, 2015. Breast cancer research and treatment. 150(3), 511-22
• ABDULJABBAR R, NEGM OH, LAI C, JERJEES DA, AL-KAABI M, HAMED MR, TIGHE PJ, BULUWELA L, MUKHERJEE A, GREEN AR, ALI S, RAKHA EA and ELLIS IO, 2015. Breast cancer research and treatment. 150(2), 335-46
• JERJEES DA, NEGM OH, ALABDULLAH ML, MIRZA S, ALKAABI M, HAMEED MR, ABDULJABBAR R, MUFTAH A, NOLAN CC, GREEN AR, TIGHE PJ, BAND V, ELLIS IO and RAKHA EA, 2015. Breast cancer research and treatment. 150(1), 91-103
• JEAN-GILLES L, BRAITCH M, LATIF ML, ARAM J, FAHEY AJ, EDWARDS LJ, ROBINS RA, TANASESCU R, TIGHE PJ, GRAN B, SHOWE LC, ALEXANDER SP, CHAPMAN V, KENDALL DA and CONSTANTINESCU CS, 2015. Acta physiologica (Oxford, England). 214(1), 63-74
• VILISAAR J, KAWABE K, BRAITCH M, ARAM J, FURTUN Y, FAHEY AJ, CHOPRA M, TANASESCU R, TIGHE PJ, GRAN B, POTHOULAKIS C and CONSTANTINESCU CS, 2015. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. PMID: 25690155,
• ALSHAREEDA, A. T., NEGM, O. H., GREEN, A. R., NOLAN, C. C., TIGHE, P., ALBARAKATI, N., SULTANA, R., MADHUSUDAN, S., ELLIS, I. O. and RAKHA, E. A., 2015. Br J Cancer. 112(12), 1929-37
• VILISAAR, J., KAWABE, K., BRAITCH, M., ARAM, J., FURTUN, Y., FAHEY, A. J., CHOPRA, M., TANASESCU, R., TIGHE, P. J., GRAN, B., POTHOULAKIS, C. and CONSTANTINESCU, C. S., 2015. J Neuroimmune Pharmacol.
• TIGHE, P. J., RYDER, R. R., TODD, I. and FAIRCLOUGH, L. C., 2015. Proteomics Clin Appl. 9(3-4), 406-22
• NEGM, O. H., HAMED, M. R., DILNOT, E. M., SHONE, C. C., MARSZALOWSKA, I., LYNCH, M., LOSCHER, C. E., EDWARDS, L. J., TIGHE, P. J., WILCOX, M. H. and MONAGHAN, T. M., 2015. Clin Vaccine Immunol.
• JERJEES, D. A., NEGM, O. H., ALABDULLAH, M. L., MIRZA, S., ALKAABI, M., HAMEED, M. R., ABDULJABBAR, R., MUFTAH, A., NOLAN, C. C., GREEN, A. R., TIGHE, P. J., BAND, V., ELLIS, I. O. and RAKHA, E. A., 2015. Breast cancer research and treatment. 150(1), 91-103
• JEAN-GILLES, L., BRAITCH, M., LATIF, M. L., ARAM, J., FAHEY, A. J., EDWARDS, L. J., ROBINS, R. A., TANASESCU, R., TIGHE, P. J., GRAN, B., SHOWE, L. C., ALEXANDER, S. P., CHAPMAN, V., KENDALL, D. A. and CONSTANTINESCU, C. S., 2015. Acta Physiol (Oxf). 214(1), 63-74
• HEATH, C. J., DEL MAR CENDRA, M., WATSON, A., AUGER, J. P., PANDEY, A., TIGHE, P. and CHRISTODOULIDES, M., 2015. PLoS One. 10(11), e0142773
• GRECO, E., AITA, A., GALOZZI, P., GAVA, A., SFRISO, P., NEGM, O. H., TIGHE, P., CASO, F., NAVAGLIA, F., DAZZO, E., DE BORTOLI, M., RAMPAZZO, A., OBICI, L., DONADEI, S., MERLINI, G., PLEBANI, M., TODD, I., BASSO, D. and PUNZI, L., 2015. Arthritis Res Ther. 17(1), 93
• GALOZZI, P., NEGM, O., GRECO, E., ALKHATTABI, N., GAVA, A., SFRISO, P., FAIRCLOUGH, L., TODD, I., TIGHE, P. and PUNZI, L., 2015. Reumatismo. 66(4), 277-84
• FAIRCLOUGH, L. C., STOOP, A. A., NEGM, O. H., RADFORD, P. M., TIGHE, P. J. and TODD, I., 2015. Eur J Immunol.
• DAFFA, N. I., TIGHE, P. J., CORNE, J. M., FAIRCLOUGH, L. C. and TODD, I., 2015. Clin Exp Immunol. 180(1), 155-63
• ABDULJABBAR, R., NEGM, O. H., LAI, C. F., JERJEES, D. A., AL-KAABI, M., HAMED, M. R., TIGHE, P. J., BULUWELA, L., MUKHERJEE, A., GREEN, A. R., ALI, S., RAKHA, E. A. and ELLIS, I. O., 2015. Breast cancer research and treatment. 150(2), 335-46
• ABDULJABBAR, R., AL-KAABI, M. M., NEGM, O. H., JERJEES, D., MUFTAH, A. A., MUKHERJEE, A., LAI, C. F., BULUWELA, L., ALI, S., TIGHE, P. J., GREEN, A., ELLIS, I. and RAKHA, E., 2015. Breast cancer research and treatment. 150(3), 511-22
• ALSHAREEDA AT, NEGM OH, GREEN AR, NOLAN C, TIGHE P, ALBARAKATI N, SULTANA R, MADHUSUDAN S, ELLIS IO and RAKHA EA, 2014. Breast cancer research and treatment. 144(3), 519-30
• ALESKANDARANY MA, NEGM OH, GREEN AR, AHMED MAH, NOLAN CC, TIGHE PJ, ELLIS IO and RAKHA EA, 2014. Breast cancer research and treatment. 145(2), 339-48
• SELVARAJAH S, NEGM OH, HAMED MR, TUBBY C, TODD I, TIGHE PJ, HARRISON T and FAIRCLOUGH LC, 2014. Mediators of inflammation. 2014, 820304
• ALOTIBY, A. A., FAIRCLOUGH, L. C., TODD, I. and TIGHE, P. J., 2014. Generation and characterisation of transcription activator-like effector nucleases (TALENs) targeting TNFR1 genome editing IMMUNOLOGY. 143, 95-95
• HALALA, R. A., TIGHE, P., TODD, I. and FAIRCLOUGH, L., 2014. Profiling of natural autoantibodies in relation to chronic obstructive pulmonary disease IMMUNOLOGY. 143, 79-79
• TARBIAH, N., TIGHE, P., FAIRCLOUGH, L. and TODD, I., 2014. Comparing between smokers and non-smokers immunoglobulin levels and B-cell differentiation IMMUNOLOGY. 143, 81-81
• ALBOGAMI, S., NEGM, O., ZANG, L., THOMAS, N., FAIRCLOUGH, L., TODD, I. and TIGHE, P., 2014. The inhibitory effects of recombinant PLAD wild type (WT) protein on the inflammatory signalling pathways IMMUNOLOGY. 143, 125-125
• HAMED, A., TODD, I., TIGHE, P., POWELL, R. and FAIRCLOUGH, L., 2014. Development of IgE microarray assays for classification of allergic individuals IMMUNOLOGY. 143, 170-170
• NEGM OH, MANNSPERGER HA, MCDERMOTT EM, DREWE E, POWELL RJ, TODD I, FAIRCLOUGH LC and TIGHE PJ, 2014. European journal of immunology. 44(7), 2096-110
• GALOZZI, P., GRECO, E., GAVA, A., BASSO, D., SFRISO, P., TIGHE, P., TODD, I. and PUNZI, L., 2014. ANNALS OF THE RHEUMATIC DISEASES. 73, 807-807
• JERJEES, D., NEJM, O., MIRZA, S., ABDULJABBAR, R., GREEN, A., TIGHE, P., BAND, V., ELLIS, I. and RAKHA, E., 2014. The biological and clinical significance of phosphorylated mTOR (pi3k/AKt pathway related) and its association with estrogen receptor and HER2 pathways VIRCHOWS ARCHIV. 465, S99-S99
• ALESKANDARANY, MOHAMMED A., NEGM, OLA H., GREEN, ANDREW R., AHMED, MOHAMED A. H., NOLAN, CHRISTOPHER C., TIGHE, PATRICK J., ELLIS, IAN O. and RAKHA, EMAD A., 2014. BREAST CANCER RESEARCH AND TREATMENT. 145(2), 339-348
• NEGM, O., MUFTAH, A., GREEN, A., NOLAN, C., TIGHE, P., ELLIS, I. and RAKHA, E., 2014. Unlocking the pathological achieves: High-throughput proteomic study for FFPE tissue using RPPA VIRCHOWS ARCHIV. 465, S24-S25
• NEGM, O., JERJEES, D., ALSHAREEDA, A., GREEN, A., BAND, V., MIRZA, S., TIGHE, P., ELLIS, I. and RAKHA, E., 2014. Proteomics of breast cancer VIRCHOWS ARCHIV. 465, S24-S24
• JERJEES, D., NEJM, O., MIRZA, S., ABDULJABBAR, R., ALSUBHI, N., NOLAN, C., GREEN, A., TIGHE, P., BAND, V., ELLIS, I. and RAKHA, E., 2014. ERK1/2 expression in breast cancer: The impact of subcellular localisation VIRCHOWS ARCHIV. 465, S107-S107
• CHOPRA C, DAVIES G, TAYLOR M, ANDERSON M, BAINBRIDGE S, TIGHE P and MCDERMOTT EM, 2014. Clinical and experimental immunology. 176(2), 275-82
• TIGHE, P., NEGM, O., TODD, I. and FAIRCLOUGH, L., 2013. Methods. 61(1), 23-29
• ALESKANDARANY, M. A., NEGM, O. H., RAKHA, E. A., AHMED, M. A., NOLAN, C. C., BALL, G. R., CALDAS, C., GREEN, A. R., TIGHE, P. J. and ELLIS, I. O., 2012. Breast cancer research and treatment. 136(2), 419-27
• VAITLA, P.M., RADFORD, P.M., TIGHE, P.J., POWELL, R.J., MCDERMOTT, E.M., TODD, I. and DREWE, E., 2011. Arthritis and Rheumatism. 63(4), 1151-1155
• DOZMOROV, I.M., JARVIS, J., SABAN, R., BENBROOK, D.M., WAKELAND, E., AKSENTIJEVICH, I., RYAN, J., CHIORAZZI, N., GUTHRIDGE, J.M., DREWE, E., TIGHE, P.J., CENTOLA, M. and LEFKOVITS, I., 2011. Nucleic Acids Research. 39(18), 7881-7899
• RENAULT, N. K., GADDIPATI, S. R., WULFERT, F., FALCONE, F. H., MIROTTI, L., TIGHE, P. J., WRIGHT, V. and ALCOCER, M. J., 2011. J Immunol Methods. 364(1-2), 21-32
• REBELO, S. L., RADFORD, P. M., BAINBRIDGE, S. E., TODD, I. and TIGHE, P. J., 2011. Adv Exp Med Biol. 691, 461-70
• KULKARNI, B.B., TIGHE, P.J., MOHAMMED, I., YEUNG, A.M., POWE, D.G., HOPKINSON, A., SHANMUGANATHAN, V.A. and DUA, H.S., 2010. BMC Genomics. 11(September), 526
• ROYER, P. J., EMARA, M., YANG, C., AL-GHOULEH, A., TIGHE, P., JONES, N., SEWELL, H. F., SHAKIB, F., MARTINEZ-POMARES, L. and GHAEMMAGHAMI, A. M., 2010. J Immunol. 185(3), 1522-31
• BARTON, S.J., KOPPELMAN, G.H., VONK, J.M., BROWNING, C.A., NOLTE, I.M., STEWART, C.E., BAINBRIDGE, S., MUTCH, S., ROSE-ZERILLI, M.J., POSTMA, D.S., MANIATIS, N., HENRY, A.P., HALL, I.P., HOLGATE, S.T., TIGHE, P., HOLLOWAY, J.W. and SAYERS, I., 2009. Journal of Allergy and Clinical Immunology. 123(6), 1391-1400.e17
• REBELO, S.L., AMEL-KASHIPAZ, M.R., RADFORD,, P.M., BAINBRIDGE, S.E., FIETS, R., FANG, J., MCDERMOTT, E.M., POWELL, R.J., TODD, I. and TIGHE, P.J., 2009. Arthritis and Rheumatism. 60(1), 269-280
• HOU, Q, CHAU, DYS, PRATOOMSOOT, C, TIGHE, PJ, DUA, HS, SHAKESHEFF, KM and ROSE, FRAJ, 2008. Journal of Pharmaceutical Sciences. 97(9), 3972-3980
• HALL, ANDREW J, MORROLL, SHAUN, TIGHE, PATRICK, G脰TZ, FRIEDRICH and FALCONE, FRANCO H, 2008. Microbes and Infection. 10(1), 69-78
• PRATOOMSOOT, C., TANIOKA, H., HORI, K., KAWASAKI, S., KINOSHITA, S., TIGHE, P.J., DUA, H., SHAKESHEFF, K.M. and ROSE, F.R.A.J., 2008. Biomaterials. 29(3), 272-281
• TODD, I., RADFORD, P.M., DAFFA, N., BAINBRIDGE, S.E., POWELL, R.J. and TIGHE, P.J., 2007. Arthritis and Rheumatism. 56(8), 2765-2773
• PRATOOMSOOT, C., TANIOKA, H., HORI, K., KAWASAKI, S., KINOSHITA, S., TIGHE, P.J., DUA, H., SHAKESHEFF, K.M. and ROSE, F.R.A.J., 2007. Biomaterials. 29(3), 272-281
• TODD, I., RADFORD, P.M., ZIEGLER-HEITBROCK, L., GHAEMMAGHAMI, A., POWELL R.J and TIGHE, P.J., 2007. Arthritis and Rheumatism. 56(12), 4182-4188
• REBELO, S.L., BAINBRIDGE, S.E., AMEL-KASHIPAZ, M.R., RADFORD, P.M., POWELL, R.J., TODD, I. and TIGHE, P.J., 2006. Arthritis and Rheumatism. 54(8), 2674-2687
• HOPKINSON, A., MCINTOSH, R.S., SHANMUGANATHAN, V., TIGHE, P.J. and DUA, H.S., 2006. Journal of Proteome Research. 5(9), 2226-2235
• GINTY, P.J., HOWARD, D., ROSE, F.R.A.J., WHITAKER, M.J., BARRY, J.J.A., TIGHE, P., MUTCH, S.R., SERHATKULU, G., OREFFO, R.O.C., HOWDLE, S.M. and SHAKESHEFF, K.M., 2006. Proceedings of the National Academy of Sciences of the United States of America. 103(19), 7426-7431
• NOWLAN, M.L., DREWE, E., BULSARA, H., ESPOSITO, N., ROBINS, R.A., TIGHE, P.J., POWELL, R.J. and TODD, I., 2006. Rheumatology. 45(1), 31-37
• HOPKINSON, A., MCINTOSH, R.S., TIGHE, P.J., JAMES, D.K. and DUA, H.S., 2006. Investigative Ophthalmology and Visual Science. 47(10), 4316-4322
• MCINTOSH, R.S., CADE, J.E., AL-ABED, M., SHANMUGANATHAN, V., GUPTA, R., BHAN, A., TIGHE, P.J. and DUA, H.S., 2005. Investigative Ophthalmology and Visual Science. 46(4), 1379-1385
• HOPKINSON, A., MCINTOSH, R.S., LAYFIELD, R., KEYTE, J., DUA, H.S. and TIGHE, P.J., 2005. Proteomics. 5(7), 1967-1979
• CONSTANTINESCU, C.S., TANI, M., RANSOHOFF, R.M., WYSOCKA, M., HILLIARD, B., FUJIOKA, T., MURPHY, S., TIGHE, P.J., SARMA, J.D., TRINCHIERI, G. and ROSTAMI, A., 2005. Journal of Neurochemistry. 95(2), 331-340
• MCCLURE, C.P., TIGHE, P.J., ROBINS, R.A., BANSAL, D., BOWMAN, C.A. and KINGSTON, M. BALL, J. K., 2005. AIDS. 19(12), 1257-1265
• TODD, I., RADFORD, P.M., DRAPER-MORGAN, K-A., MCINTOSH, R., BAINBRIDGE, S., DICKINSON, P., JAMHAWI, L., SANSARIDIS, M., HUGGINS, M.L., TIGHE, P.J. and POWELL. R.J., 2004. Immunology. 113(1), 65-79
• HUGGINS, M.L., RADFORD, P.M., MCINTOSH, R.S., BAINBRIDGE, S.E., DICKINSON, P., DRAPER-MORGAN, K-A., TIGHE, P.J., POWELL, R.J. and TODD, I., 2004. Arthritis and Rheumatism. 50(8), 2651-2659
• EL GHRABLY, I., POWE, D.G., ORR, G., FISCHER, D., MCINTOSH, R., DUA, H.S. and TIGHE, P.J., 2004. Investigative Ophthalmology and Visual Science. 45(5), 1473-9
• DROMEY, J. A., WEENINK, S. M., PETERS, G. H., ENDL, J., TIGHE, P. J., TODD, I. and CHRISTIE, M. R., 2004. Mapping of Epitopes for Autoantibodies to the Type 1 Diabetes Autoantigen IA-2 by Peptide Phage Display and Molecular Modeling: Overlap of Antibody and T Cell Determinants The Journal of Immunology. VOL 172(PART 7), 4084-4090
• MYRA,C., SLOPER,L., TIGHE,P.J., MCINTOSH,R.S., STEVENS,S.E., GREGSON,R.H.S., SOKAL,M., HAYNES,A.P. and POWELL,R.J., 2004. British Journal of Ophthalmology. 88(6), 844-847
• JOSEPH, ANNIE, HOSSAIN, PARWEZ, JHAM, SEEMA, JONES, RHODRI E, TIGHE, PADDY, MCINTOSH, RICHARD S and DUA, HARMINDER S, 2003. Investigative Ophthalmology and Visual Science. 44(11), 4689-92
• MCKAIG, B.C., HUGHES, K., TIGHE, P.J. and MAHIDA, Y.R., 2002. American Journal of Physiology: Cell Physiology. 282(1), C172-C182
• TIGHE, P.J., STEVENS, S.E., DEMPSEY, S., LE DEIST, F., RIEUX-LAUCAT, F. and EDGAR, J.D.M., 2002. Genes and Immunity. 3(Supplement 1), S66-S70
• AL-BUKHARI, T.A.M.A., RADFORD, P.M., BOURAS, G., DAVENPORT, C., TRIGWELL, S.M., BOTTAZZO, G.-F., LAI, M., SCHWARTZ, H.L., TIGHE, P.J. and TODD, I., 2002. Clinical and Experimental Immunology. 130(1), 131-139
• MORGAN, J. P., ROBINS, R. A., DUA, H. S. and TIGHE, P. J., 2002. British Journal of Ophthalmology. VOL 86(PART 5), 517-520
• AL-BUKHARI, T. A., TIGHE, P. and TODD, I., 2002. Journal of Immunological Methods. VOL 264(NUMBER 1-2), 163-171
• GRABOWSKA, A.M., LECHNER, F., KLENERMAN, P., TIGHE, P.J., RYDER, S., BALL, J.K., THOMSON, B.J., IRVING, W.L. and ROBINS, R.A., 2001. European Journal of Immunology. 31(8), 2388-2394
• WELLS, D.B., TIGHE, P.J., WOOLDRIDGE, K.G., ROBINSON, K. and ALA'ALDEEN, D.A.A., 2001. Infection and Immunity. 69(4), 2718-2722
• WILSON, Z.A., MORROLL, S.M., DAWSON, J., SWARUP, R. and TIGHE, P.J., 2001. Plant Journal. 28(1), 27-39
• SIMON, A., VAN DEUREN, M., TIGHE, P. J., VAN DER MEER, J. W. M. and DRENTH, J. P. H., 2001. Archives of Internal Medicine. VOL 161(PART 20), 2491-2496
• MCINTOSH, R. S., HUGGINS, M. L., KONTOGIANNIS, V., TIGHE, P. J. and POWELL, R. J., 2001. Rheumatology International. VOL 21(PART 2), 53-57
• EL-GHRABLY, I A, DUA, H S, ORR, G M, FISCHER, D and TIGHE, P J, 2001. British Journal of Ophthalmology. 85(4), 461-70
• EL-SHERIFF, A. M., SETH, R., TIGHE, P. J. and JENKINS, D., 2001. Journal of Pathology. VOL 195(PART 2), 179-185
• HAYNES, R. J., MCELVEEN, J. E., DUA, H. S., TIGHE, P. J. and LIVERSIDGE, J., 2000. Expression of Human Beta-Defensins in Intraocular Tissues Investigative Ophthalmology and Visual Science. VOL 41(PART 10), 3026-3031
• EL-SHERIF, A. M., SETH, R., TIGHE, P. J. and JENKINS, D., 2000. Journal of Pathology. VOL 192(PART 4), 494-501
• FURMONAVICIENE, R., TIGHE, P.J., CLARK, M.R., SEWELL, H.F. and SHAKIB, F., 1999. Clinical and Experimental Allergy. VOL 29(NUMBER 11), 1563-1571
• TIGHE, P.J, POWELL-RICHARDS, A., SEWELL, H.F., FISCHER, D., DONOSO, L. and DUA, H.S., 1999. Experimental Eye Research. 68(6), 679-84
• HAYNES, R J, TIGHE, P J and DUA, H S, 1999. British Journal of Ophthalmology. 83(6), 737-41
• HAYNES, R. J., TIGHE, P. J., SCOTT, R. A. H. and DUA, H. S., 1999. Experimental Eye Research. VOL 69(NUMBER 4), 397-404
• EL-GHRABLY, I. A., DUA, H. S., ORR, G. M., FISCHER, D. and TIGHE, P. J., 1999. British Journal of Ophthalmology. VOL 83(NUMBER 11), 1296-1299
• HUGGINS, M. L., TODD, I., CAVERS, M. A., PAVULURI, S. R., TIGHE, P. J. and POWELL, R. J., 1999. Clinical and Experimental Immunology. VOL 118(NUMBER 2), 322-328
• HAYNES, R J, TIGHE, P J and DUA, H S, 1998. Lancet. 352(9126), 451-2
• HOLBROOK, M. R., TIGHE, P. J. and POWELL, R. J., 1996. Annals of the Rheumatic Diseases. VOL 55(NUMBER 9), 627-631
• TIGHE, P.J., POWELL-RICHARDS, A, FRANKEL, T, SEWELL, HF, DONOSO, L and DUA, HS, 1996. Determination Of the Epitope Requirements Of an Anti-IRBP Monoclonal- Antibody Investigative Ophthalmology and Visual Science. 37(3), 2474-2474
• TIGHE,P.J. and STEVENS,S., 1996. T-cell expansions in the vitreous infiltrate and subretinal exudate in autoimmune uveoretinitis(abstract Bb307) Immunology. 89(suppl 1), 80
• TIGHE, P J, LIVERSIDGE, J, FORRESTER, J V and SEWELL, H F, 1995. Annals of the New York Academy of Sciences. 756, 421-3
• COUTINHO, H B, SEWELL, H F, TIGHE, P, KING, G, NOGUEIRA, J C, ROBALINHO, T I, COUTINHO, V B and CAVALCANTI, V M, 1995. Immunocytochemical study of the ontogeny of the marsupial Didelphis albiventris immune system. Journal of Anatomy. 187 ( Pt 1), 37-46
• TIGHE, P.J., FORRESTER, J.V., LIVERSIDGE, J. and SEWELL, H.F., 1995. Peripheral CD25 positive T lymphocytes with biased T cell receptor V脽 gene usage in autoimmune endogenous posterior uveitis Journal of Clinical Pathology: Molecular Pathology. 48, M46-M50
• LAING,, TIGHE,, KWIATKOWSKI,, MILLIGAN,, PRICE, and SEWELL,, 1995. Selection of peptide ligands for the antimucin core antibody C595 using phage display technology: definition of candidate epitopes for a cancer vaccine. Clinical molecular pathology. 48(3), M136-M141
• TIGHE, P. J., GOYAL, P. K., WILSON, Z. A. and WAKELIN, D., 1994. MOLECULAR AND BIOCHEMICAL PARASITOLOGY. VOL 63(NUMBER 1), 175
• QUINNELL, R. J., SLATER, A. F. G., TIGHE, P. and WALSH, E. A., 1994. TRANSACTIONS- ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE. VOL 88(NUMBER 1), 44
• QUINNELL, R J, SLATER, A F, TIGHE, P, WALSH, E A, KEYMER, A E and PRITCHARD, D I, 1993. Reinfection with hookworm after chemotherapy in Papua New Guinea. Parasitology (Cambridge). 106 ( Pt 4), 379-85
• DAWSON, S P, WILDE, C J, TIGHE, P J and MAYER, R J, 1993. Characterization of two novel casein transcripts in rabbit mammary gland. Biochemical Journal. 296 ( Pt 3), 777-84