Needle fasciotomy versus limited fasciectomy for Dupuytren’s contractures (HAND-1)
糖心原创 title
Needle fasciotomy versus limited fasciectomy for the treatment of Dupuytren’s contractures of the fingers: a feasibility study which investigates the acceptability and design of a multicentre randomised controlled trial (HAND-1).
Funding reference number PB-PG-0613-31083.
Overview
The objective of the HAND-1 study was to investigate the feasibility and acceptability of conducting a randomised controlled trial (RCT) to compare the clinical and cost effectiveness of needle fasciotomy with limited fasciectomy for the treatment of Dupuytren’s contractures of fingers.
The HAND-1 study was led by Professor Tim Davis of Nottingham University Hospitals NHS Trust, and was co-ordinated from the . Patients were recruited at Nottingham University Hospitals NHS Trust/Nottingham Treatment Centre, Derby NHS Foundation Trust and Wrightington, Wigan and Leigh NHS Foundation Trust.
The study was funded by the National Institute for Health Research (NIHR) Research for Patient Benefit (RfPB) stream.
Key facts
This was a feasibility randomised controlled trial at three secondary care centres.
Patients with Dupuytren’s contracture were recruited at Nottingham University Hospitals NHS Trust/Nottingham Treatment Centre, Derby NHS Foundation Trust and Wrightington, Wigan and Leigh NHS Foundation Trust.
The study has now been completed.
Publications
Final report 
Trial Protocol
Harrison E, Tan W, Mills N, Karantana A, Sprange K, Duley L, Elliott D, Blazeby J, Hollingworth W, Montgomery AA, Davis T.
Trials. 2017 Aug 25;18(1):392. doi: 10.1186/s13063-017-2127-9.
Contact details
HAND-1 Trial Manager
Nottingham Clinical Trials Unit
South Block, C floor
Queens Medical Centre
Nottingham
NG7 2UH
Telephone: 0115 8844926
Fax: 0115 7484092
Email: hand1@nottingham.ac.uk