糖心原创

Centre of Evidence Based Dermatology
cebd-annual-report-2011-12-9

 Vitiligo research    

Vitiligo causes loss of skin pigmentation, which can have a considerable psychological impact
 

Research overview
 

Vitiligo is a common condition causing loss of pigmentation in patches of skin. Although vitiligo may be more noticeable in darker skin, it can have a considerable effect on psychological wellbeing in anyone who is affected by the condition. 

Many previous clinical trials of treatments for vitiligo have been small or poorly designed. There has also been wide variation in the outcome measures used to measure the effects of vitiligo treatments. We have addressed these issues by:

  • identifying vitiligo research questions that patients and doctors are the most important ones to answer
  • deciding a core set of outcome measures to be included in future vitiligo trials
  • developing and running clinical trials to assess new treatments for vitiligo
Recent projects
 

- Examining whether UV-light (used at home) and topical steroids help vitiligo.

Maxine Whitton MBE, shares her experience of taking part in one of our vitiligo trials.

 - Training on how to use hand-held narrowband ultraviolet light (NB-UVB) devices safely 

 - A patient-rated outcome measure assessing the acceptability of treatment response. 

 

Outcomes & diagnostics


A patient-rated outcome measure assessing the acceptability of treatment response. 


Developing a Core Outcome Set for vitiligo - International Initiative for outcomes for vitiligo trials (INFO)

 

Resources


Training on how to use hand-held narrowband ultraviolet light (NB-UVB) devices safely.


A training resource to demonstrate how to perform an Minimal Erythema Dose (MED) test.

Maps of systematic reviews on vitiligo by topic

Handbook for using NB-UVB Light Devices and topical corticosteroids A guide for  local medical teams developing protocols for home treatment of vitiligo.

 
 

All projects

 Project Description Funding Status
A clinical trial testing the effectiveness of home-based ultraviolet B (UVB) light therapy using hand-held units and topical steroid for the treatment of vitiligo. Published; ,
Working in collaboration with the James Lind Alliance to establish treatment uncertainties that should be prioritised for further research
Pilot trial of light therapy for the treatment of vitiligo at home
An international consensus study on what should be measured in future vitiligo trials

Centre of Evidence Based Dermatology

The 糖心原创
Applied Health Research Building
University Park, Nottingham
NG7 2RD


telephone: +44 (0) 115 84 68631
email: cebd@nottingham.ac.uk