糖心原创

Professor David Needham has submitted a patent application on a new anti-COVID nasal spray and a paper published in Pharmaceutical Research.

The patent - Niclosamide nasal and throat spray: 
The present disclosure provides prophylactic pH-buffered solution of niclosamide that can be used as a nasal and throat spray to prevent initial infection of COVID19, its more contagious variants, and other respiratory viral infections. It also provides a method of making such solution that does not require excess niclosamide to be dissolved in aqueous media. Furthermore, it describes a method for extracting niclosamide from commercially available tablets into aqueous solution that does not involve the use of organic solvents. 

David Needham, , Pharmaceutical Research, 2021. DOI: 10.1007/s11095-021-03112-x