糖心原创

Contact

• workRoom C214e BDI
  University Park
  Nottingham
  NG7 2RD
  UK
• A.Mata@nottingham.ac.uk
• www.mataresearch.com

Biography

Alvaro Mata is Professor in Biomedical Engineering and Biomaterials in the School of Pharmacy and the Department of Chemical and Environmental Engineering at the 糖心原创. He holds a Bachelor's Degree from the University of Kansas, a Master's Degree from the University of Strathclyde, and a Doctor of Engineering Degree from Cleveland State University working with Prof. Shuvo Roy at the Cleveland Clinic. He conducted his postdoctoral training with Prof. Samuel Stupp at Northwestern University.

His group works at the interface of supramolecular chemistry, structural biology, biofabrication, and engineering to develop bioinspired approaches to design and fabricate innovative materials and devices for tissue engineering and regenerative medicine. For example, by utilizing biological processes such as protein disorder-to-order transitions, compartmentalization, or diffusion-reaction processes as predictive steps of biofabrication methods, it is possible to grow functional structures that exhibit structural and functional properties of biological systems.

His work has led to seven patents or patent applications; publications in journals including Nature Chemistry, Nature Communications, Science Advances, and Advanced Functional Materials; and awards such as a Ramon y Cajal Fellowship and an ERC Staring Grant. More information can be found at: www.mataresearch.com/, https://twitter.com/mata_lab.

Alvaro Mata is part of the Advanced Materials Research group.

Expertise Summary

Our Lab's research and expertise: https://www.mataresearch.com/research

Our Lab's publications: https://www.mataresearch.com/publications

Research Summary

Our group integrates supramolecular chemistry, structural biology, biofabrication, and engineering to develop new ways to build with biomolecules. Our aim is to create functional materials, devices,… read more

Recent Publications

• MART脥NEZ-ESPUGA, M., MATA, A. and ORD脫脩EZ-MOR脕N, P., 2023. . In: Methods in Molecular Biology 2650. 235-243
• HILL, J., WILDMAN, R. and MATA, A., 2022. Current Opinion in Biotechnology. 74, 42-54
• BU, W. H., WU, Y. H., GHAEMMAGHAMI, A. M., SUN, H. C. and MATA, A., 2022. Rational design of hydrogels for immunomodulation: Regenerative Biomaterials Regenerative Biomaterials. 9,
• WU, Y., YANG, J., VAN TEIJLINGEN, A., BERARDO, A., CORRIDORI, I., FENG, J., XU, J., TITIRICI, M. M., RODRIGUEZ-CABELLO, J. C., PUGNO, N. M., SUN, J., WANG, W., TUTTLE, T. and MATA, A., 2022. Advanced Functional Materials.

• View all publications

Current Research

Our group integrates supramolecular chemistry, structural biology, biofabrication, and engineering to develop new ways to build with biomolecules. Our aim is to create functional materials, devices, and fabrication processes that tackle and overcome major challenges in tissue engineering and regenerative medicine. We use biological phenomena such as protein order-disorder synergies, molecular self-assembly, compartmentalization, and diffusion-reaction processes in combination with techniques such as bioprinting and microfabrication. These methodologies are being used for the regeneration of a variety of soft and hard tissues as well as the engineering of more effective in vitro models. Our aim is to transform sophisticated molecular design into engineering functionality with societal impact and, in this effort, our work expands from answering fundamental questions to developing translatable technologies.

Learn more about our research: https://www.mataresearch.com/research

Learn more about our publications: https://www.mataresearch.com/publications

Future Research

His group works at the interface of supramolecular chemistry, structural biology, biofabrication, and engineering to develop bioinspired approaches to design and fabricate innovative materials and devices for tissue engineering and regenerative medicine. For example, by utilizing biological processes such as protein disorder-to-order transitions, compartmentalization, or diffusion-reaction processes as predictive steps of biofabrication methods, it is possible to grow functional structures that exhibit structural and functional properties of biological system

• MART脥NEZ-ESPUGA, M., MATA, A. and ORD脫脩EZ-MOR脕N, P., 2023. . In: Methods in Molecular Biology 2650. 235-243
• HILL, J., WILDMAN, R. and MATA, A., 2022. Current Opinion in Biotechnology. 74, 42-54
• BU, W. H., WU, Y. H., GHAEMMAGHAMI, A. M., SUN, H. C. and MATA, A., 2022. Rational design of hydrogels for immunomodulation: Regenerative Biomaterials Regenerative Biomaterials. 9,
• WU, Y., YANG, J., VAN TEIJLINGEN, A., BERARDO, A., CORRIDORI, I., FENG, J., XU, J., TITIRICI, M. M., RODRIGUEZ-CABELLO, J. C., PUGNO, N. M., SUN, J., WANG, W., TUTTLE, T. and MATA, A., 2022. Advanced Functional Materials.
• WU, Y. H., OKESOLA, B. O., CONNELLY, J., OREFFO, R. O. C., RODRIGUEZ-CABELLO, J. C., VOZZI, G., AZEVEDO, H. S., PUGNO, N. M. and MATA, A., 2022. INTEGRATING MOLECULAR SELF-ASSEMBLY AND ADDITIVE MANUFACTURING FOR THE BIOFABRICATION OF MICROFLUIDIC DEVICES WITH BIOLOGICALLY RELEVANT PROPERTIES: Tissue Engineering Part A Tissue Engineering Part A. 28, S282-S282
• HASAN, A., MARSHALL, K., WOJCIECHOWSKI, J., ELSHARKAWY, S., EGLIN, D., OREFFO, R., STEVENS, M. and MATA, A., 2022. HIERARCHICALLY MINERALIZING 3D PRINTED SCAFFOLDS FOR HARD TISSUE REGENERATION: Tissue Engineering Part A Tissue Engineering Part A. 28, S350-S351
• MATA, A., 2022. SUPRAMOLECULAR BIOFABRICATION: FROM MOLECULAR CONTROL TO MACROSCOPIC FUNCTIONALITY: Tissue Engineering Part A Tissue Engineering Part A. 28, S4-S4
• HASAN, A., BAGNOL, R., OWEN, R., LATIF, A., ROSTAM, H. M., ELSHARKAWY, S., ROSE, FRAJ, RODRIGUEZ-CABELLO, J. C., GHAEMMAGHAMI, A. M., EGLIN, D. and MATA, A., 2022. Mineralizing Coating on 3D Printed Scaffolds for the Promotion of Osseointegration: Frontiers in Bioengineering and Biotechnology Frontiers in Bioengineering and Biotechnology. 10,
• MAJKOWSKA, A., INOSTROZA-BRITO, K. E., GONZALEZ, M., REDONDO-G脫MEZ, C., RICE, A., RODRIGUEZ-CABELLO, J. C., DEL RIO HERNANDEZ, A. E. and MATA, A., 2022. Biomacromolecules.
• SENNETT, M. L., FRIEDMAN, J. M., ASHLEY, B. S., STOECKL, B. D., PATEL, J. M., ALINI, M., CUCCHIARINI, M., EGLIN, D., MADRY, H., MATA, A., SEMINO, C., STODDART, M. J., JOHNSTONE, B., MOUTOS, F. T., ESTES, B. T., GUILAK, F., MAUCK, R. L. and DODGE, G. R., 2021. European cells & materials. 41, 40-51
• PRIMO, G. A. and MATA, A., 2021. Advanced Functional Materials.
• WU, Y. H., FORTUNATO, G. M., OKESOLA, B. O., DI BROCCHETTI, F. L. P., SUNTORNNOND, R., CONNELLY, J., DE MARIA, C., RODRIGUEZ-CABELLO, J. C., VOZZI, G., WANG, W. and MATA, A., 2021. An interfacial self-assembling bioink for the manufacturing of capillary-like structures with tuneable and anisotropic permeability: Biofabrication Biofabrication. 13(3), 14
• DENG, X., HASAN, A., ELSHARKAWY, S., TEJEDA-MONTES, E., TARAKINA, N. V., GRECO, G., NIKULINA, E., STORMONTH-DARLING, J. M., CONVERY, N., RODRIGUEZ-CABELLO, J. C., BOYDE, A., GADEGAARD, N., PUGNO, N. M., AL-JAWAD, M. and MATA, A., 2021. Materials Today Bio. 11,
• OKESOLA, B. O., MENDOZA-MARTINEZ, A. K., CIDONIO, G., DERKUS, B., BOCCORH, D. K., OSUNA DE LA PE脩A, D., ELSHARKAWY, S., WU, Y., DAWSON, J. I., WARK, A. W., KNANI, D., ADAMS, D. J., OREFFO, R. O. C. and MATA, A., 2021. ACS Nano. 15(7), 11202鈥�11217
• AJOVALASIT, A., REDONDO-GOMEZ, C., SABATINO, M. A., OKESOLA, B. O., BRAUN, K., MATA, A. and DISPENZA, C., 2021. Carboxylated-xyloglucan and peptide amphiphile co-assembly in wound healing: Regenerative Biomaterials Regenerative Biomaterials. 8(5),
• SHI, Y., WAREHAM, D. W., YUAN, Y., DENG, X., MATA, A. and AZEVEDO, H. S., 2021. Advanced Healthcare Materials.
• OSUNA DE LA PE脩A, D., TRABULO, S. M. D., COLLIN, E., LIU, Y., SHARMA, S., TATARI, M., BEHRENS, D., ERKAN, M., LAWLOR, R. T., SCARPA, A., HEESCHEN, C., MATA, A. and LOESSNER, D., 2021. Nature Communications. 12(1),
• MENDOZA-MARTINEZ, A. K., LOESSNER, D., MATA, A. and AZEVEDO, H. S., 2021. Cancers. 13(22),
• WU, Y., OKESOLA, B. O., XU, J., KOROTKIN, I., BERARDO, A., CORRIDORI, I., DI BROCCHETTI, F. L. P., KANCZLER, J., FENG, J., LI, W., SHI, Y., FARAFONOV, V., WANG, Y., THOMPSON, R. F., TITIRICI, M. M., NERUKH, D., KARABASOV, S., OREFFO, R. O. C., CARLOS RODRIGUEZ-CABELLO, J., VOZZI, G., AZEVEDO, H. S., PUGNO, N. M., WANG, W. and MATA, A., 2020. Nature Communications. 11(1),
• DERKUS, B., OKESOLA, B. O., BARRETT, D. W., D'ESTE, M., CHOWDHURY, T. T., EGLIN, D. and MATA, A., 2020. Acta Biomaterialia.
• HEDEGAARD, C. L. and MATA, A., 2020. Integrating self-assembly and biofabrication for the development of structures with enhanced complexity and hierarchical control: Biofabrication Biofabrication. 12(3), 22
• MAJKOWSKA, A., REDONDO-G脫MEZ, C., RICE, A., GONZALEZ, M., INOSTROZA-BRITO, K. E., COLLIN, E. C., RODRIGUEZ-CABELLO, J. C., DEL RIO HERNANDEZ, A. E., SOLITO, E. and MATA, A., 2020. Frontiers in Materials. 7,
• REDONDO-GOMEZ, C., PADILLA-LOPATEGUI, S., AZEVEDO, H. S. and MATA, A., 2020. Host-Guest-Mediated Epitope Presentation on Self-Assembled Peptide Amphiphile Hydrogels: Acs Biomaterials Science & Engineering Acs Biomaterials Science & Engineering. 6(9), 4870-4880
• BARRETT, D. W., OKESOLA, B. O., COSTA, E., THRASIVOULOU, C., BECKER, D. L., MATA, A., DEPREST, J. A., DAVID, A. L. and CHOWDHURY, T. T., 2020. Prenatal Diagnosis.
• HEDEGAARD, C. L., REDONDO-G脫MEZ, C., TAN, B. Y., NG, K. W., LOESSNER, D. and MATA, A., 2020. Science Advances. 6(40),
• REDONDO-GOMEZ, C., PADILLA-LOPATEGUI, S., MATA, A. and AZEVEDO, H. S., Peptide Amphiphile Hydrogels Based on Homoternary Cucurbit 8 uril Host-Guest Complexes: Bioconjugate Chemistry Bioconjugate Chemistry.
• GHOSH, M., MAJKOWSKA, A., MIRSA, R., BERA, S., RODRIGUEZ-CABELLO, J. C., MATA, A. and ADLER-ABRAMOVICH, L., Disordered Protein Stabilization by Co-Assembly of Short Peptides Enables Formation of Robust Membranes: Acs Applied Materials & Interfaces ACS applied materials & interfaces.