I work at the interface of computational modelling, MRI physics, and neuroscience developing novel methodology for neuroimage analysis. Broadly, my scientific goal is to achieve a better understanding of the structural and functional organisation of the brain at a systems level. To this end, my group () develops computational methods and algorithmic/modelling frameworks for mapping brain connections and neuronal tissue microstructure using MRI, all the way from image reconstruction and processing to high-throughput analytics.
My algorithms and software tools enable imaging-derived phenotyping at scale and are widely used worldwide. In basic neuroscience for untangling the complexity of the human brain and study evolution and neurodevelopment. In clinical neuroscience for brain-symptom mapping and imaging-guided treatment targeting.
Over the years, I have been a major contributor to Open Science initiatives and to large-scale international efforts for pushing the boundaries in neuroimaging technologies (Human Connectome Projects, UK Biobank, NIH Centre for Mesoscale Connectomics). I have attracted funding from national and international funders (UKRI, European Research Council, US National Institutes of Health), charities (Wellcome Trust) and industry.
Developing novel forms of neurotechnology
National Institutes of Health (NIH) Centre for Mesoscale, Connectomics, Developing cutting-edge technologies for mapping brain connections for precision diagnostics and therapeutics.
On stability of Canonical Correlation Analysis and Partial Least Squares with application to brain-behavior associations. Helmer M, Warrington S, Mohammadi-Nejad AR, Ji JL, Howell A, Rosand B, Anticevic A, Sotiropoulos SN*, Murray JD*
Denoising Diffusion MRI: Considerations and implications for analysis. Manzano-Patron JP, Moeller S, Andersson JLR, Ugurbil K, Yacoub E, Sotiropoulos SN
Concurrent mapping of brain ontogeny and phylogeny within a common space: standardised tractography and applications. Warrington S, Thompson E, Bastiani M, Dubois J, Baxter L, Slater R, Jbabdi S, Mars RB, Sotiropoulos SN
XTRACT - Standardised protocols for automated tractography in the human and macaque brain. Warrington S, Bryant KL, Khrapitchev AA, Sallet J, Charquero-Ballester M, Douaud G, Jbabdi S, Mars RB, Sotiropoulos SN
Hierarchical Heterogeneity across Human Cortex Shapes Large-Scale Neural Dynamics. Demirtas M, Burt JB, Helmer M, Ji JL, Adkinson BD, Glasser MF, Van Essen DC, Sotiropoulos SN, Anticevic A, Murray JD
The 糖心原创University Park Nottingham, NG7 2RD