糖心原创

Faculty of Science

Professor Philip M Bath

Stroke Association Professor of Stroke Medicine

philip.bath@nottingham.ac.uk

My research focuses on the clinical diagnosis and treatment of post-stroke dysphagia (PSD). PSD is common and associated with a poor outcome.

I have been involved with, then led, phase-2, -3 and -4 trials of pharyngeal electrical stimulation (PES) for PSD. The ongoing HTA PhEAST trial addresses NICE requirements for definitive evidence that PES is safe and effective; if the trial is positive, then PES will be introduced into widespread NHS use.

I have supported the development and phase-2 testing of cerebellar repetitive transcranial magnetic stimulation (rTMS) for PSD. We are considering whether to test this at phase-3.

These works have supported 3 PhD students, all speech & language therapists.

Phillip 4x4-3
 

N3Centre Research Interests
  • Understanding neural mechanisms
  • Clinical translation/application of neurotechnology.
 

 

Current projects

Project title: HTA Pharyngeal Electrical stimulation for Acute Stroke dysphagia Trial (PhEAST). 

Funding: £2.1m, NIHR 

Key Publications

  • Scutt P, Lee HS, Hamdy S, Bath PM. Stroke Res Treat. 2015;2015:429053. 

 

  • Bath PM, Scutt P, Love J, Clavé P, Cohen D. et al. Swallowing Treatment Using Pharyngeal Electrical Stimulation (STEPS) Trial Investigators. Stroke 2016 Jun;47(6):1562-70

 

  • Dziewas R, Stellato R, van der Tweel I, Walther E. et al. PHAryngeal electrical STimulation for early decannulation in TRACheotomised stroke patients with neurogenic dysphagia (PHAST-TRAC): a prospective randomised single-blinded trial. Lancet Neurology 2018; 17; 849-59

  

  • Bath PM, Woodhouse LJ, Suntrup-Krueger S, Likar R, et al. Pharyngeal electrical stimulation for neurogenic dysphagia following stroke, traumatic brain injury or other causes: Main results from the PHADER cohort study. EClinicalMedicine. 2020 Nov 10;28:100608. doi: 10.1016/j.eclinm.2020.100608. PMID: 33294818; PMCID: PMC7700977

Access the paper

  • Cheng I, Bath PM, Hamdy S, Muhle P, Mistry S, Dziewas R, Suntrup-Krueger S. Neurotherapeutics. 2024 Aug 23:e00433.

  

  • Sasegbon A, Watanabe M, Simons A, Michou E, Vasant DH, Magara J, Bath PM, Rothwell J, Inoue M, Hamdy S. J Physiol. 2019 May;597(9):2533-2546. doi: 10.1113/JP277545. Epub 2019 Apr 3. PMID: 30907429 

  

  • Sasegbon A, Smith CJ, Bath P, Rothwell J, Hamdy S. Exp Brain Res. 2020 Mar 30. doi: 10.1007/s00221-020-05787-x

 

Phillip 4x4-2
 
 

 

 

Faculty of Science

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