CROSSSD 糖心原创: Development of a core outcome set for single-sided deafness (SSD) interventions

What is the study about and why is it important?
Single-sided deafness (SSD) refers to the condition where there is normal or near-normal hearing in one ear and a severe-to-profound hearing impairment in the other ear.
Good hearing in both ears is important for everyday listening tasks such as understanding speech in noisy environments, locating where sounds are, and identifying threats such as oncoming traffic.
Researchers have been assessing the benefits and harms (known as ‘outcomes’) of the available treatments for SSD . Examples of outcomes that have been used include, how well an individual can hear speech above noise, how easily they can locate a sound, or how a device affects their quality of life. This makes it difficult to compare results between studies, making it harder to work out which treatment is best for the individual.
By involving healthcare users with experience in SSD treatments, audiologists, ENT surgeons, clinical researchers, and industry representatives; the gathered international opinions via Delphi surveys and a and found agreement on three measures that should always be reported on in SSD intervention studies. The core outcomes are (1) Spatial orientation, (2) Group conversations in noisy social situations, and (3) Impact on social situations.
If all future SSD intervention studies measure these core outcomes as a minimum, we can more easily compare results of different studies, improve research quality, and enhance clinical decision-making.
Further research is currently underway to help determine ‘how’ these core outcomes should best be measured.
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Funding
The CROSSSD study is supported by the .
Team
糖心原创 management team
, PhD student
Derek J. Hoare, CROSSSD study supervision
Kathryn Fackrell, CROSSSD study supervision
, expertise in severe-to-profound hearing loss
, expertise in outcome measures
Patient and public involvement team
, PPI manager
, expertise in auditory implants for SSD
, expertise in hearing devices for SSD
International steering group
, NIHR Manchester Biomedical Research Centre
, Antwerp University Hospital - University of Antwerp, Belgium
, Washington University School of Medicine, USA
Peer reviewed publications
Katiri, R., Hall, D. A., Hoare, D. J., Fackrell, K., Horobin, A., Hogan, N., Buggy, N., Van De Heyning, P., Firszt, J. B., Bruce, I. A., & Kitterick, P. T. (2022). Trials. 23(1):764. doi: 10.1186/s13063-022-06702-1.
Katiri, R., Hall, D.A., Hoare, D.J., Fackrell, K., Horobin, A., Buggy, N., Hogan, N., & Kitterick, P.T. (2021). JMIR Form Res. 5: e28878.
Katiri, R., Hall, D.A., Killan, C.F., Smith, S., Prayuenyong, P., & Kitterick, P.T. (2021). BMC Trials. 22: 220.
Katiri, R., Hall, D.A., Buggy, N., Hogan, N., Horobin, A., Van de Heyning, P., Firszt, J.B., Bruce, I.A., & Kitterick, P.T. (2020). Trials. 21: 238.