糖心原创

Cells, Organisms and Molecular Genetics

Our research team

The Cells, Organisms and Molecular Genetics team here at the 糖心原创’s School of Life Sciences is a diverse, collaborative group of researchers. We’re academics, postdoctoral research fellows, research technicians and postgraduate students, all working together to break new ground and make a real impact on the world around us.

Image of Andrew Renault

Andrew Renault

Assistant Professor, Faculty of Medicine & Health Sciences

Contact

Biography

BSc (Biochemistry and Molecular Biology), University of Durham, 1992-1996 with industrial placement at Glaxo Wellcome

DPhil (Genetics), University of Oxford, 1996-2001

Postdoctoral researcher, NYU School of Medicine, 2001-2007 under Dr Ruth Lehmann

Group leader, Max Planck Institute for Developmental Biology, T眉bingen, 2007-2013

Lecturer, School of Life Sciences, 糖心原创, 2013 - present

Expertise Summary

Our lab is focused on understanding development, the change from a simple egg to a complex multicellular organism. We use the fruit fly as our model system and focus on the formation of specific organs including the embryonic gonad, as well as the development of the airway (tracheal) system. These are linked by the requirement for a particular type of lipid modification enzyme and we are interested in understanding how lipid modifications are important for these processes

Teaching Summary

I am the exams officer for the biology, zoology and genetics BSc and MSci degrees.

Convenor:

Year 2: Higher Skills in the biological sciences: Bioinformatics

Year 2: Building brains

Year 4: Research Presentation Skills

Contributor:

Year 2: Developmental Biology

Year 3: Advanced Developmental Biology

Research Summary

Our lab is interested in understanding how cellular behaviour is regulated during embryonic development. We use the fruit fly Drosophila melanogaster as our model system and combine genetics,… read more

Recent Publications

  • RENAULT, ANDREW D, 2024. Optogenetic control of Drosophila neurons: a laboratory practical for undergraduates and outreach Journal of Microbiology and Biology Education. e00086-24
  • MUKHERJEE, AMRITA, SCHUPPE, MICHAELA and RENAULT, ANDREW D, 2023. The Lipid Phosphate Phosphatase Wunen Promotes Eggshell Formation and Is Essential for Fertility in Drosophila Biology. 12(7), 1003
  • KENWRICK, KIM, MUKHERJEE, AMRITA and RENAULT, ANDREW D., 2019. JOURNAL OF CELL SCIENCE. 132(23),
  • HAACK T, SCHNEIDER M, SCHWENDELE B and RENAULT AD, 2014. Developmental biology. 396(2), 169-82

Current Research

Our lab is interested in understanding how cellular behaviour is regulated during embryonic development. We use the fruit fly Drosophila melanogaster as our model system and combine genetics, immunohistochemistry, confocal microscopy and live imaging.

Our focus is understanding how germ cells (the cells that give rise to sperm and eggs in the adult), the tracheal system (the airway of flies) and heart cells are influenced by lipid signals. We pursue an additional strand of research into the interaction of germ cells with the somatic cells of the embryonic gonad.

We are always interested in recruiting motivated new team members who have a fascination for research and are interested in tackling fundamental questions in cell behaviour and signalling.

  • RENAULT, ANDREW D, 2024. Optogenetic control of Drosophila neurons: a laboratory practical for undergraduates and outreach Journal of Microbiology and Biology Education. e00086-24
  • MUKHERJEE, AMRITA, SCHUPPE, MICHAELA and RENAULT, ANDREW D, 2023. The Lipid Phosphate Phosphatase Wunen Promotes Eggshell Formation and Is Essential for Fertility in Drosophila Biology. 12(7), 1003
  • KENWRICK, KIM, MUKHERJEE, AMRITA and RENAULT, ANDREW D., 2019. JOURNAL OF CELL SCIENCE. 132(23),
  • HAACK T, SCHNEIDER M, SCHWENDELE B and RENAULT AD, 2014. Developmental biology. 396(2), 169-82
  • TRIPATHY R, KUNWAR PS, SANO H and RENAULT AD, 2014. Developmental biology. 392(2), 193-208
  • ILE, K. E. and RENAULT, A. D., 2013. Fly. 7(1), 18-22
  • MUKHERJEE, A., NEHER, R.A. and RENAULT, A.D., 2013. Journal of Cell Science. n/a(n/a), n/a
  • ANDREW J. MORRIS, SUSAN S. SMYTH, ABDEL K. SALOUS and ANDREW D. RENAULT, 2013. . In: JEROLD CHUN, TIMOTHY HLA, SARA SPIEGEL and WOUTER MOOLENAAR, eds., Lysophospholipid Receptors: Signaling and Biochemistry 1. John Wiley & Sons. 229-263
  • RENAULT, A. D., 2012. Biology Open. 1(10), 1043-8
  • ILE, K.E., TRIPATHY, R., GOLDFINGER, V. and RENAULT, A.D., 2012. Development. 139(14), 2535-2546
  • SANO, H., KUNWAR, P. S., RENAULT, A. D., BARBOSA, V., CLARK, I. B., ISHIHARA, S., SUGIMURA, K. and LEHMANN, R., 2012. PloS One. 7(12), e52649
  • RENAULT, A.D., KUNWAR, P.S. and LEHMANN, R., 2010. Development. 137(11), 1815-1823
  • RENAULT, A. D., RICARDO, S., KUNWAR, P. S., SANTOS, A., STARZ-GAIANO, M., STEIN, J. A. and LEHMANN, R., 2009. Developmental Biology. 328(2), 355-62
  • KUNWAR, P.S., SANO, H., RENAULT, A.D., BARBOSA, V., FUSE, N. and LEHMANN, R., 2008. Journal of Cell Biology. 183(1), 157-168
  • RENAULT, A. D. and LEHMANN, R., 2006. Current opinion in genetics & development. 16(4), 348-54
  • SANO, H., RENAULT, A. D. and LEHMANN, R., 2005. The Journal of Cell Biology. 171(4), 675-83
  • RENAULT, A. D., SIGAL, Y. J., MORRIS, A. J. and LEHMANN, R., 2004. Science. 305(5692), 1963-6
  • ZHANG, X. H., AXTON, J. M., DRINJAKOVIC, J., LORENZ, L., WHITE-COOPER, H. and RENAULT, A. D., 2004. 117(Pt 16), 3571-8
  • RENAULT, A. D. and AXTON, J. M., 2003. 307, 77-86
  • RENAULT, A. D., ZHANG, X. H., ALPHEY, L. S., FRENZ, L. M., GLOVER, D. M., SAUNDERS, R. D. and AXTON, J. M., 2003. 130(13), 2997-3005
  • RENAULT, A, STARZ-GAIANO, M and LEHMANN, R, 2003. Gene Expression Patterns. 3(4), 546
  • RENAULT, A. D., STARZ-GAIANO, M. and LEHMANN, R., 2002. 119 Suppl 1, S293-301

Cells, Organisms and Molecular Genetics

School of Life Sciences
糖心原创
Medical School
Queen's Medical Centre
Nottingham NG7 2UH