糖心原创

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Mark Dunning

Professor of Small Animal Internal Medicine, Faculty of Medicine & Health Sciences

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Teaching Summary

I deliver lectures, practicals and facilitated sessions on the majority of the clinical modules including urinary, LCB, cardiotrespiratory, endocrinology and gastroenterology.

I previously ran the final year small animal referral rotation which focused on developing clinical reasoning skills and practical techniques using referral cases to enable a deep appreciation of clinical medicine.

Research Summary

One of my current areas of research activity is in the development of non-invasive diagnostic techniques and the validation of point-of-care methodologies to expand the possibilities for cases to be… read more

Selected Publications

  • GREENHALGH SN, REEVE JA, JOHNSTONE T, GOODFELLOW MR, DUNNING MD, O'NEILL EJ, HALL EJ, WATSON PJ and JEFFERY ND, 2014. Journal of the American Veterinary Medical Association. 245(5), 527-33
  • STEINBACH, SARAH M. L., STURGESS, CHRISTOPHER P., DUNNING, MARK D. and NEIGER, RETO, 2015. RESEARCH IN VETERINARY SCIENCE. 100, 263-264
  • CHIKAZAWA, S. and DUNNING, M. D., 2016. JOURNAL OF SMALL ANIMAL PRACTICE. 57(7), 348-353
  • JENNIFER CARTWRIGHT, MALCOLM COBB and MARK DUNNING, 2019. A pilot study evaluating the monitoring of canine diabetes mellitus in primary care practice Veterinary Record Open. (In Press.)

Current Research

One of my current areas of research activity is in the development of non-invasive diagnostic techniques and the validation of point-of-care methodologies to expand the possibilities for cases to be investigated and diseases monitored in primary care practice. A number of current projects are being carried out including those evaluating remote markers of disease activity in blood, urine and faeces.

In addition, allied to the development of techniques to facilitate the effective investigation and management of cases in primary-care practice, we are developing research projects to address important questions arising from problems encountered in primary care practice. These are developing in liaison with the evidence-based medicine group. Our network is currently working directly with primary-care practices avoiding extrapolating anticipated outcomes from referral populations.

A further area of my research activity is in the development of owner and breeder focused canine research. This approach has been designed to empower and enhance owner and breeder involvement in prospective research projects. The ethos is that those people owning and breeding dogs have fundamental questions over the health of their animals. This approach is therefore dedicated to facilitating the development of these concerns into active research projects. At present we are collaborating with a number of breed groups and involve a number of primary research and clinical research groups within the School of Veterinary medicine and Science and the 糖心原创 and other groups in the UK, along with groups in the USA and Europe. One particular area of breed-specific research is into the apparent breed predispositions to the develop and outcome of canine osteosarcoma and other cancers. This is in collaboration with a number of groups both within and outside of the 糖心原创. This research is allied to similar research in humans and in breeds in both the USA and Europe.

In addition to these areas, I am passionate about student engagement with research and run clinical research projects for students who are keen to experience research. These projects are designed around the students individual areas of interest. These projects have invariably led to students presenting their research at international conferences and writing their research up for publication in peer reviewed journals.

Past Research

My historic research background is in experimental neuroscience. This primarily investigated the potential for glial cells to be labeled with a number of different paramagnetic contrast agents in vitro prior to transplantation into the CNS. The impact of this labeling on the function of the glial cells was assessed both in vitro and in vivo. The ability of the fates of those labeled cells to be followed in vivo using MRI was also investigated at various time points.

Other historic areas of clinical research have included the use of radiotherapy to treat cats with acromegaly, the comparative outcome of dogs managed with medical and surgical approaches that are suffering with portosystemic shunts, identifying therapeutic markers in dogs with nasal tumours and clotting disorders in Weimaraners.

  • SIMPSON, SIOBHAN, DUNNING, MARK, DE BROT, SIMONE, ALIBHAI, AZIZA, BAILEY, CLARA, WOODCOCK, CORINNE L, MESTAS, MADELINE, AKHTAR, SHAREEN, JEYAPALAN, JENNIE N, LOTHION-ROY, JENNIFER, EMES, RICHARD D, ALLEGRUCCI, CINZIA, RIZVANOV, ALBERT A, MONGAN, NIGEL P and RUTLAND, CATRIN S, 2020. Cancers. 12(9),
  • MOONEY, CARMEL T., SHIEL, ROBERT E., SEKIYA, MARY, DUNNING, MARK and GUNN, EILIDH, 2020. FRONTIERS IN VETERINARY SCIENCE. 7,
  • SIMPSON, SIOBHAN, DUNNING, MARK, DE BROT, SIMONE, ALIBHAI, AZIZA, BAILEY, CLARA, WOODCOCK, CORINNE L., MESTAS, MADELINE, AKHTAR, SHAREEN, JEYAPALAN, JENNIE N., LOTHION-ROY, JENNIFER, EMES, RICHARD D., ALLEGRUCCI, CINZIA, RIZVANOV, ALBERT A., MONGAN, NIGEL P. and RUTLAND, CATRIN S., 2020. CANCERS. 12(9),
  • WESTON, PHILIPPA, MORALES, CARLES, DUNNING, MARK, PARRY, ANDREW and CARRERA, INES, 2020. Susceptibility weighted imaging at 1.5 Tesla magnetic resonance imaging in dogs: Comparison with T2*-weighted gradient echo sequence and its clinical indications VETERINARY RADIOLOGY & ULTRASOUND. 61(5), 566-576
  • CROFT, RACHEL, CLEMENTI, ELISABETTA, BVM, HELEN FARMER, BVM, RACHEL WHALLEY, DUNNING, MARK and FIRTH, AVA, 2020. JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE.
  • SHUTTLEWORTH A, DUNNING M, WRIGHT I and ELSHEIKHA HM, 2019. Veterinary parasitology, regional studies and reports. 14, 144-149
  • ALLERTON, FERGUS, FISHWICK, JOHN, PATERSON, SUSAN, WELLER, RENATE, BATTERSBY, IAN, DOYLE, RONAN, GOULD, DAVID, CADDY, SARAH, DUNNING, MARK, FEATHERSTONE, HEIDI J, HARDY, JON, KENT, ANDREW, PEDRO, BRIGITE, SMITH, KINLEY, SWINBOURNE, FAYE, HARRIS, JAMES, HEINRICH, CHRISTINE, LAU-GILLARD, PERI, LOEFFLER, ANETTE, MADDINSON, REBECCA, MASON, CARLY, RAMSEY, IAN, RIDYARD, ALISON, ROBIN, LOUISE, SCUDDER, CHRISTOPHER, SETH, MAYANK, TAPPIN, SIMON, SINGLETON, DAVID, SMITH, HEATHER, SOUTHERDEN, PETER, WARLAND, JAMES, WHITEHEAD, MARTIN and WILLIAMS, JOHN, 2019. Call for coordinated antimicrobial approach at veterinary diagnostic laboratories. The Veterinary record. 184(26), 805-806
  • POSPORIS C, BELTRAN E, DUNNING M, ESPADAS I, GILLESPIE S, BARRY AT and WESSMANN A, 2019. Frontiers in veterinary science. 6, 415
  • JAFFEY JA, PAVLICK M, WEBSTER CR, MOORE GE, MCDANIEL KA, BLOIS SL, BRAND EM, REICH CF, MOTSCHENBACHER L, HOSTNIK ET, SU D, LIDBURY JA, RAAB O, CARR SV, MABRY KE, FOX-ALVAREZ W, TOWNSEND S, PALERMO S, NAKAZONO Y, OHNO K, VANEERDE E, FIETEN H, HULSMAN AH, COOLEY-LOCK K, DUNNING M, KISIELEWICZ C, ZOIA A, CALDIN M, CONTI-PATARA A, ROSS L, MANSFIELD C, LYNN O, CLAUS MA, WATSON PJ, SWALLOW A, YOOL DA, GOMMEREN K, KNOPS M, CEPLECHA V, DE ROOSTER H, LOBETTI R, DOSSIN O, JOLIVET F, PAPAZOGLOU LG, PAPPALARDO MCF, MANCZUR F, DUD脕S-GY脰RKI Z, O'NEILL EJ, MARTINEZ C, GAL A, OWEN RL, GUNN E, BROWN K, HARDER LK, GRIEBSCH C, ANFINSEN KP, GRON TK, MARCHETTI V, HEILMANN RM, PAZZI P and DECLUE AE, 2019. Veterinary journal (London, England : 1997). 251, 105350
  • DOR C, GAJANAYAKE I, KORTUM A, DAY MJ, TAPPIN S, HARRIS B, BATTERSBY I, WALKER D, GLANEMANN B, MYATT P, DUNNING M and BEXFIELD N, 2019. The Journal of small animal practice. 60(9), 551-558
  • POLLEDO L, GRINWIS GCM, GRAHAM P, DUNNING M and BAIKER K, 2018. Veterinary pathology. 55(6), 880-888
  • ALLERTON F, SWINBOURNE F, BARKER L, BLACK V, KATHRANI A, TIVERS M, HENRIQUES T, KISIELEWICZ C, DUNNING M and KENT A, 2018. Journal of veterinary internal medicine. 32(5), 1618-1628
  • SIMPSON S, DUNNING MD, BROWNLIE S, PATEL J, GODDEN M, COBB M, MONGAN NP and RUTLAND CS, 2017. BioMed research international. 2016, 6374082
  • SIMPSON S, DUNNING MD, DE BROT S, GRAU-ROMA L, MONGAN NP and RUTLAND CS, 2017. Acta veterinaria Scandinavica. 59(1), 71
  • DUNNING M, MAY J, ADAMANY J, HEPTINSTALL S and FOX S, 2017. Journal of veterinary internal medicine. 32(1), 119-127
  • ADAMANY JL, CROSS GF, GARDNER D and DUNNING MD, 2017. The Journal of small animal practice. 58(7), 403-407
  • DUNNING M, 2017. The Veterinary record. 180(9), 222-223
  • 2016. The Journal of small animal practice. (In Press.)
  • CHIKAZAWA, S. and DUNNING, M. D., 2016. JOURNAL OF SMALL ANIMAL PRACTICE. 57(7), 348-353
  • STEINBACH, SARAH M. L., STURGESS, CHRISTOPHER P., DUNNING, MARK D. and NEIGER, RETO, 2015. RESEARCH IN VETERINARY SCIENCE. 100, 263-264
  • GREENHALGH SN, REEVE JA, JOHNSTONE T, GOODFELLOW MR, DUNNING MD, O'NEILL EJ, HALL EJ, WATSON PJ and JEFFERY ND, 2014. Journal of the American Veterinary Medical Association. 245(5), 527-33
  • CHARLESWORTH TM, DUNNING M, SCASE TJ and ANDERSON DM, 2012. The Journal of small animal practice. 54(1), 36-9
  • BELSHAW Z, CONSTANTIO-CASAS F, BREARLEY MJ, DUNNING MD, HOLMES MA and DOBSON JM, 2011. Veterinary And Comparative Oncology. 9(2), 141-8
  • GREENHALGH SN, DUNNING MD, MCKINLEY TJ, GOODFELLOW MR, KELMAN KR, FREITAG T, O'NEILL EJ, HALL EJ, WATSON PJ and JEFFERY ND, 2010. Journal Of The American Veterinary Medical Association. 236(11), 1215-20
  • DUNNING MD, AVERIS GF, PATTINSON H, TARGETT M, CADE S and HERRTAGE ME, 2009. The Journal Of Small Animal Practice. 50(7), 357-9
  • DUNNING MD, LOWRIE CS, BEXFIELD NH, DOBSON JM and HERRTAGE ME, 2009. Journal Of Veterinary Internal Medicine / American College Of Veterinary Internal Medicine. 23(2), 243-9
  • MELLOR PJ, FETZ K, MAGGI RG, HAUGLAND S, DUNNING M, VILLIERS EJ, MELLANBY RJ, WILLIAMS D, BREITSCHWERDT E and HERRTAGE ME, 2006. Journal Of Veterinary Internal Medicine / American College Of Veterinary Internal Medicine. 20(4), 1023-8
  • DUNNING MD, KETTUNEN MI, FFRENCH CONSTANT C, FRANKLIN RJM and BRINDLE KM, 2006. Neuroimage. 31(1), 172-80
  • DUNNING MD, LAKATOS A, LOIZOU L, KETTUNEN M, FFRENCH-CONSTANT C, BRINDLE KM and FRANKLIN RJM, 2004. The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience. 24(44), 9799-810
  • PENDERIS J, WOODRUFF RH, LAKATOS A, LI W, DUNNING MD, ZHAO C, MARCHIONNI M and FRANKLIN RJM, 2003. The European Journal Of Neuroscience. 18(8), 2253-64
  • DUNNING, M and STONEHEWER, J, 2002. Urinary Tract Infections In Small Animals: Pathophysiology And Diagnosis In Practice. 24(8), 418-+
  • DUNNING, M and STONEHEWER, J, 2002. Urinary Tract Infections In Small Animals: Therapeutic Options And Management Of Problem Cases In Practice. 24(9), 518-+
  • LASCELLES BD, DAVISON L, DUNNING M, BRAY JP and WHITE RA, 1998. The Journal Of Small Animal Practice. 39(10), 475-80

Biobank

The 糖心原创
School of Veterinary Medicine and Science
Sutton Bonington Campus, Leicestershire, LE12 5RD


telephone: +44 (0) 115 951 6563
email:sv-biobank@nottingham.ac.uk