糖心原创

Contact

• workRoom C28 Boots Science Building
  University Park
  Nottingham
  NG7 2RD
  UK
• work0115 951 5151
• Ale.Carabelli@nottingham.ac.uk

Biography

As an NRF fellow, I am currently focusing on controlling the foreign body response related to macro-devices used for cellular therapeutic delivery in diabetes treatment. This research, a collaborative effort between MIT and the 糖心原创, represents a cutting-edge frontier in biomedical engineering. I'm excited to contribute my expertise to this innovative field.

Prior to this, I worked as a consultant in the life sciences sector, advising on a range of projects spanning clinical research and biotechnology. This role further honed my skills in applying scientific innovation to real-world challenges. My previous research experience includes a significant stint at the University of Cambridge, where I joined in 2020. There, I contributed to virology research, focusing notably on SARS-CoV-2 evolution and the impact of mutations on viral fitness and immune escape. My work led to the identification of the British Alpha variant.

Before Cambridge, I completed my PhD at the 糖心原创 (2015-2019) under the guidance of Professors Paul Williams, Morgan Alexander, and Andrew Hook. My doctoral research focused on discovering acrylate polymers resistant to bacterial attachment and uncovering the biological mechanisms driving these interactions. These experiences at Nottingham and Cambridge have deepened my passion for research that has a meaningful impact on society.

Expertise Summary

Cell therapies for type I diabetes, novel biomaterial development, characterize immune responses to bio-materials, in vivo testing various diabetes models, complex hydrogel manufacture and system design

Recent Publications

• CARABELLI, A. M., PEACOCK, T. P., THORNE, L. G., HARVEY, W. T., HUGHES, J., COVID- GENOMICS UK CONSORTIUM, PEACOCK, S. J., BARCLAY, W. S., DE SILVA, T. I., TOWERS, G. J. and ROBERTSON, D. L., 2023. Nat Rev Microbiol. 21(3), 162-177
• COX, M., PEACOCK, T. P., HARVEY, W. T., HUGHES, J., WRIGHT, D. W., COVID- GENOMICS UK CONSORTIUM, WILLETT, B. J., THOMSON, E., GUPTA, R. K., PEACOCK, S. J., ROBERTSON, D. L. and CARABELLI, A. M., 2023. Nat Rev Microbiol. 21(2), 112-124
• DUBERN, J. F., HOOK, A. L., CARABELLI, A. M., CHANG, C. Y., LEWIS-LLOYD, C. A., LUCKETT, J. C., BURROUGHS, L., DUNDAS, A. A., HUMES, D. J., IRVINE, D. J., ALEXANDER, M. R. and WILLIAMS, P., 2023. Sci Adv. 9(4), eadd7474
• KOTOWSKA, A. M., ZHANG, J., CARABELLI, A., WATTS, J., AYLOTT, J. W., GILMORE, I. S., WILLIAMS, P., SCURR, D. J. and ALEXANDER, M. R., 2023. Anal Chem. 95(49), 18287-18294

• View all publications

• CARABELLI, A. M., PEACOCK, T. P., THORNE, L. G., HARVEY, W. T., HUGHES, J., COVID- GENOMICS UK CONSORTIUM, PEACOCK, S. J., BARCLAY, W. S., DE SILVA, T. I., TOWERS, G. J. and ROBERTSON, D. L., 2023. Nat Rev Microbiol. 21(3), 162-177
• COX, M., PEACOCK, T. P., HARVEY, W. T., HUGHES, J., WRIGHT, D. W., COVID- GENOMICS UK CONSORTIUM, WILLETT, B. J., THOMSON, E., GUPTA, R. K., PEACOCK, S. J., ROBERTSON, D. L. and CARABELLI, A. M., 2023. Nat Rev Microbiol. 21(2), 112-124
• DUBERN, J. F., HOOK, A. L., CARABELLI, A. M., CHANG, C. Y., LEWIS-LLOYD, C. A., LUCKETT, J. C., BURROUGHS, L., DUNDAS, A. A., HUMES, D. J., IRVINE, D. J., ALEXANDER, M. R. and WILLIAMS, P., 2023. Sci Adv. 9(4), eadd7474
• KOTOWSKA, A. M., ZHANG, J., CARABELLI, A., WATTS, J., AYLOTT, J. W., GILMORE, I. S., WILLIAMS, P., SCURR, D. J. and ALEXANDER, M. R., 2023. Anal Chem. 95(49), 18287-18294
• DUBERN, J. F., ROMERO, M., MAI-PROCHNOW, A., MESSINA, M., TRAMPARI, E., GIJZEL, H. N., CHAN, K. G., CARABELLI, A. M., BARRAUD, N., LAZENBY, J., CHEN, Y., ROBERTSON, S., MALONE, J. G., WILLIAMS, P., HEEB, S. and CAMARA, M., 2022. NPJ Biofilms Microbiomes. 8(1), 64
• HILL, V., DU PLESSIS, L., PEACOCK, T. P., AGGARWAL, D., COLQUHOUN, R., CARABELLI, A. M., ELLABY, N., GALLAGHER, E., GROVES, N., JACKSON, B., MCCRONE, J. T., O'TOOLE, A., PRICE, A., SANDERSON, T., SCHER, E., SOUTHGATE, J., VOLZ, E., BARCLAY, W. S., BARRETT, J. C., CHAND, M., CONNOR, T., GOODFELLOW, I., GUPTA, R. K., HARRISON, E. M., LOMAN, N., MYERS, R., ROBERTSON, D. L., PYBUS, O. G. and RAMBAUT, A., 2022. Virus Evol. 8(2), veac080
• WRIGHT, D. W., HARVEY, W. T., HUGHES, J., COX, M., PEACOCK, T. P., COLQUHOUN, R., JACKSON, B., ORTON, R., NIELSEN, M., HSU, N. S., COVID- GENOMICS UK CONSORTIUM, HARRISON, E. M., DE SILVA, T. I., RAMBAUT, A., PEACOCK, S. J., ROBERTSON, D. L. and CARABELLI, A. M., 2022. Virus Evol. 8(1), veac023
• ROMERO, M., CARABELLI, A., R. SWIFT M and I. SMITH M, 2022. Environ Microbiol. 24(3), 1560-1572
• HARVEY, W. T., CARABELLI, A. M., JACKSON, B., GUPTA, R. K., THOMSON, E. C., HARRISON, E. M., LUDDEN, C., REEVE, R., RAMBAUT, A., COVID- GENOMICS UK CONSORTIUM, PEACOCK, S. J. and ROBERTSON, D. L., 2021. Nat Rev Microbiol. 19(7), 409-424
• MENG, B., KEMP, S. A., PAPA, G., DATIR, R., FERREIRA, IATM, MARELLI, S., HARVEY, W. T., LYTRAS, S., MOHAMED, A., GALLO, G., THAKUR, N., COLLIER, D. A., MLCOCHOVA, P., COVID- GENOMICS UK CONSORTIUM, DUNCAN, L. M., CARABELLI, A. M., KENYON, J. C., LEVER, A. M., DE MARCO, A., SALIBA, C., CULAP, K., CAMERONI, E., MATHESON, N. J., PICCOLI, L., CORTI, D., JAMES, L. C., ROBERTSON, D. L., BAILEY, D. and GUPTA, R. K., 2021. Cell Rep. 35(13), 109292
• CARABELLI, A. M., ISGRO, M., SANNI, O., FIGUEREDO, G. P., WINKLER, D. A., BURROUGHS, L., BLOK, A. J., DUBERN, J. F., PAPPALARDO, F., HOOK, A. L., WILLIAMS, P. and ALEXANDER, M. R., 2020. ACS Appl Bio Mater. 3(12), 8471-8480
• HOOK, A. L., FLEWELLEN, J. L., DUBERN, J. F., CARABELLI, A. M., ZAID, I. M., BERRY, R. M., WILDMAN, R. D., RUSSELL, N., WILLIAMS, P. and ALEXANDER, M. R., 2019. mSystems. 4(5),
• WAIT, R., BEGUM, S., BRAMBILLA, D., CARABELLI, A. M., CONSERVA, F., ROCCO GUERINI, A., EBERINI, I., BALLERIO, R., GEMEINER, M., MILLER, I. and GIANAZZA, E., 2005. Amino Acids. 28(3), 239-72