糖心原创

School of Pharmacy

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Barrie Kellam

Professor of Medicinal Chemistry, Head of School, Faculty of Science

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Biography

I am a Pharmacist and gained my PhD from the School of Pharmacy at the 糖心原创 under the supervision of Prof Barrie Bycroft. After an eighteen month postdoctoral position at the School of Pharmacy, London under the mentorship of Prof Istvan Toth I was appointed to a lectureship at Nottingham in 1997. I was promoted to Associate Professor in 2006 and full Professor in 2013.

I was the co-founder and Director of Medicinal Chemistry of a successful spin-out from the 糖心原创, CellAura Technologies Ltd between 2006-2014.

I was a member of the General Pharmaceutical Council's (GPhC) Accreditation & Recognition Panel between 2012-2021 and I am currently chair of the Royal Pharmaceutical Society's (RPS) Science and Research Committee, helping provide strategic leadership, advocacy and expert advice around pharmaceutical sciences and pharmacy research in the UK and internationally.

Teaching (Undergraduate)

MPharm:

PHAR1002 (Essential Skills for Pharmacy)

PHAR1003 (Dyspepsia)

PHAR2005 (Pain)

PHAR4012 (Advanced Drug Discovery)

MSci: Pharmaceutical Sciences

PHAR1020 (Synthesis of Simple Drugs)

Teaching (Postgraduate)

MSc in Drug Discovery & Pharmaceutical Sciences

PHAR4006 (Fundamentals of Drug Discovery)

PHAR4008 (Drug Discovery and Development I)

Research Summary

My academic research is focussed around small molecule synthetic medicinal chemistry, especially pertaining to G Protein Coupled Receptors (GPCRs), making significant scientific and commercial… read more

Selected Publications

  • DISNEY AJ, KELLAM B and DEKKER LV, 2016. ChemMedChem. 11(9), 972-9
  • STODDART, LEIGH A., VERNALL, ANDREA J., BRIDDON, STEPHEN J., KELLAM, BARRIE and HILL, STEPHEN J., 2015. NEUROPHARMACOLOGY. 98, 68-77
  • SCHEMBRI, LUKE S., STODDART, LEIGH A., BRIDDON, STEPHEN J., KELLAM, BARRIE, CANALS, MERITXELL, GRAHAM, BIM* and SCAMMELLS, PETER J.*, 2015. JOURNAL OF MEDICINAL CHEMISTRY. 58(24), 9754-9767
  • SCHWEHM, CAROLIN, LI, JIN, SONG, HONGMEI, HU, XIAO, KELLAM, BARRIE and STOCKS, MICHAEL J., 2015. ACS Medicinal Chemistry Letters. 6, 324-328

Current Research

My academic research is focussed around small molecule synthetic medicinal chemistry, especially pertaining to G Protein Coupled Receptors (GPCRs), making significant scientific and commercial contributions in this area. Developing an international reputation in fluorescent small molecule ligand synthesis through a highly productive collaborative programme with Prof Steve Hill in applying fluorescent-based technologies to characterise and interrogate ligand-receptor interactions for a number of class A GPCRs in living cells; leading to development of novel high-throughput fluorescence-based assays for identification of new medicinal agents.

This also allowed single-cell pharmacological measurements to be undertaken in primary cells, with publications in PNAS, FASEB, Chemistry & Biology and J Med Chem highlighting our successes. Patents generated from this work formed background IP to leverage equity-based investment to spin out CellAura Technologies Ltd. In 2006.

I have led the medicinal chemistry component in drug discovery programmes, e.g. a 拢2.8M funded Seeding Drug Discovery programme from the Wellcome Trust. Over a 2-year period we synthesised over 1500 novel compounds as part of a focussed lead optimisation programme for future treatment of patients with concomitant cardiovascular and respiratory disease. From a highly selective 尾1-adrenoceptor partial agonist 'hit', structure optimisation generated a suite of high affinity pure antagonists, with improved selectivity over other 尾-adrenoceptor subtypes. We generated three drug candidate series, all displaying good oral bioavailability, pronounced 尾1mediated reduction of heart rate with no 尾2-mediated side-effects. These compounds possessed excellent disposition properties without adverse toxicology.

All of the studies above have necessitated a joined-up approach using in silico and traditional synthetic medicinal chemistry methods to help reach fruition and have provided a highly varied environment to help train over 40 PhD students and postdoctoral researchers.

In my academic career, I have published over 80 scientific papers and patents, supervised 36 PhD students and mentored 10 postdoctoral fellows; many of whom are now in senior positions within the pharmaceutical industry or academia.

Memberships of Committees and Professional Bodies

  • Fellow of the Royal Pharmaceutical Society of Great Britain
  • Member of the Royal Society of Chemistry
  • Chair of the Royal Pharmaceutical Society's Science and Research Committee
  • COMEO, ELEONORA, TRINH, PHUC, NGUYEN, ANH T., NOWELL, CAMERON J., KINDON, NICHOLAS D., SOAVE, MARK, STODDART, LEIGH A., WHITE, JONATHAN M., HILL, STEPHEN J., KELLAM, BARRIE, HALLS, MICHELLE L., MAY, LAUREN T. and SCAMMELLS, PETER J., 2021. JOURNAL OF MEDICINAL CHEMISTRY. 64(10), 6670-6695
  • SOUKARIEH, FADI, MASHABI, ALAA, RICHARDSON, WILLIAM, OTON, EDUARD VICO, ROMERO, MANUEL, ROBERSTON, SHAUN N., GROSSMAN, SCOTT, SOU, TOMAS, LIU, RUILING, HALLIDAY, NIGEL, KUKAVICA-IBRULJ, IRENA, LEVESQUE, ROGER C., BERGSTROM, CHRISTEL A. S., KELLAM, BARRIE, EMSLEY, JONAS, HEEB, STEPHAN, WILLIAMS, PAUL, STOCKS, MICHAEL J. and CAMARA, MIGUEL, 2021. ACS INFECTIOUS DISEASES. 7(9), 2666-2685
  • SOUKARIEH, FADI, MASHABI, ALAA, RICHARDSON, WILLIAM, OTON, EDUARD VICO, ROMERO, MANUEL, ROBERSTON, SHAUN N., GROSSMAN, SCOTT, SOU, TOMAS, LIU, RUILING, HALLIDAY, NIGEL, KUKAVICA-IBRULJ, IRENA, LEVESQUE, ROGER C., BERGSTROM, CHRISTEL A. S., KELLAM, BARRIE, EMSLEY, JONAS, HEEB, STEPHAN, WILLIAMS, PAUL, STOCKS, MICHAEL J. and CA虂MARA, MIGUEL, 2021. ACS Infectious Diseases. 7(9), 2666-2685
  • DAMASKINAKI, FOTEINI-NAFSIKA, MORAN, LUIS A., GARCIA, ANGEL, KELLAM, BARRIE and WATSON, STEVE P., 2021. Platelets. 32(6), 744-752
  • STODDART, LEIGH A., KILPATRICK, LAURA E., CORRIDEN, ROSS, KELLAM, BARRIE, BRIDDON, STEPHEN J. and HILL, STEPHEN J., 2021. The FASEB Journal. 35(4), e21211
  • COMEO, ELEONORA, TRINH, PHUC, NGUYEN, ANH T, NOWELL, CAMERON J, KINDON, NICHOLAS D, SOAVE, MARK, STODDART, LEIGH A, WHITE, JONATHAN M, HILL, STEPHEN J, KELLAM, BARRIE, HALLS, MICHELLE L, MAY, LAUREN T and SCAMMELLS, PETER J, 2021. Journal of Medicinal Chemistry. 64(10), 6670-6695
  • GOULDING, JO脣LLE, MISTRY, SARAH J., SOAVE, MARK, WOOLARD, JEANETTE, BRIDDON, STEPHEN J., WHITE, CARL W., KELLAM, BARRIE and HILL, STEPHEN J., 2021. Pharmacology Research & Perspectives. 9(3), e00779
  • GILLIS A, GONDIN AB, KLIEWER A, SANCHEZ J, LIM HD, ALAMEIN C, MANANDHAR P, SANTIAGO M, FRITZWANKER S, SCHMIEDEL F, KATTE TA, REEKIE T, GRIMSEY NL, KASSIOU M, KELLAM B, KRASEL C, HALLS ML, CONNOR M, LANE JR, SCHULZ S, CHRISTIE MJ and CANALS M, 2020. Science signaling. 13(625),
  • COMEO, ELEONORA, KINDON, NICHOLAS D., SOAVE, MARK, STODDART, LEIGH A., KILPATRICK, LAURA E., SCAMMELLS, PETER J., HILL, STEPHEN J. and KELLAM, BARRIE, 2020. JOURNAL OF MEDICINAL CHEMISTRY. 63(5), 2656-2672
  • STODDART, LEIGH A., KINDON, NICHOLAS D., OTUN, OMOLADE, HARWOOD, CLARE R., PATERA, FOTEINI, VEPRINTSEV, DMITRY B., WOOLARD, JEANETTE, BRIDDON, STEPHEN J., FRANKS, HESTER A., HILL, STEPHEN J. and KELLAM, BARRIE, 2020. COMMUNICATIONS BIOLOGY. 3(1),
  • BAKER, JILLIAN G, FROMONT, CHRISTOPHE, BRUDER, MARJORIE, THOMPSON, KEVIN S J, KELLAM, BARRIE, HILL, STEPHEN J, GARDINER, SHEILA M and FISCHER, PETER M, 2020. ACS Pharmacology & Translational Science.
  • MATOS, THIAGO KELVIN BRITO, BATISTA, PEDRO HENRIQUE JATAI, ROCHO, FERNANDA DOS REIS, VITA, DANIELA DE, PEARCE, NICHOLAS, KELLAM, BARRIE, MONTANARI, CARLOS ALBERTO and LEIT脙O, ANDREI, 2020. Bioorganic & Medicinal Chemistry Letters. 30(18), 127439
  • STEPHENSON, ZOE A, HARVEY, ROBERT F, PRYDE, KENNETH R, MISTRY, SARAH, HARDY, RACHEL E, SERRELI, RICCARDO, CHUNG, INJAE, ALLEN, TIMOTHY EH, STONELEY, MARK, MACFARLANE, MARION, FISCHER, PETER M, HIRST, JUDY, KELLAM, BARRIE and WILLIS, ANNE E, 2020. eLife. 9, e55845
  • SOAVE, MARK, HEUKERS, RAIMOND, KELLAM, BARRIE, WOOLARD, JEANETTE, SMIT, MARTINE J, BRIDDON, STEPHEN J and HILL, STEPHEN J, 2020. Cell Chemical Biology.
  • STODDART, LEIGH A., KINDON, NICHOLAS D., OTUN, OMOLADE, HARWOOD, CLARE R., PATERA, FOTEINI, VEPRINTSEV, DMITRY B., WOOLARD, JEANETTE, BRIDDON, STEPHEN J., FRANKS, HESTER A., HILL, STEPHEN J. and KELLAM, BARRIE, 2020. Communications Biology. 3(1), 722
  • GILLIS, ALEXANDER, GONDIN, ARISBEL B, KLIEWER, ANDREA, SANCHEZ, JULIE, LIM, HERMAN D, ALAMEIN, CLAUDIA, MANANDHAR, PREETI, SANTIAGO, MARINA, FRITZWANKER, SEBASTIAN, SCHMIDEL, FRANK, KATTE, TIMOTHY A, REEKIE, TRISTAN, GRIMSEY, NATASHA L, KASSIOU, MICHAEL, KELLAM, BARRIE, KRASEL, CORNELIUS, HALLS, MICHELLE L, CONNOR, MARK, LANE, J ROBERT, SCHULZ, STEFAN, CHRISTIE, MACDONALD J and CANALS, MERITXELL, 2020. Science signaling. 13(625), eaaz3140
  • COMEO, ELEONORA, KINDON, NICHOLAS D, SOAVE, MARK, STODDART, LEIGH A, KILPATRICK, LAURA E, SCAMMELLS, PETER J, HILL, STEPHEN J and KELLAM, BARRIE, 2020. Journal of medicinal chemistry.
  • TIM J. FYFE, BARRIE KELLAM, DAVID A. SYKES, BEN CAPUANO, PETER J. SCAMMELLS, J. ROBERT LANE, STEVEN J. CHARLTON and SHAILESH N. MISTRY, 2019. Journal of Medicinal Chemistry. 62(21), 9488-9520
  • FYFE, TIM J., ZARZYCKA, BARBARA, LIM, HERMAN D., KELLAM, BARRIE, MISTRY, SHAILESH N., KATRICH, VSEVOLOD, SCAMMELLS, PETER J., LANE, J. ROBERT and CAPUANO, BEN, 2019. JOURNAL OF MEDICINAL CHEMISTRY. 62(1), 174-206
  • FYFE, TIM J., KELLAM, BARRIE, SYKES, DAVID A., CAPUANO, BEN, SCAMMELLS, PETER J., LANE, J. ROBERT, CHARLTON, STEVEN J. and MISTRY, SHAILESH N., 2019. JOURNAL OF MEDICINAL CHEMISTRY. 62(21), 9488-9520
  • ADLERE, ILZE, CASPAR, BIRGIT, ARIMONT, MARTA, DEKKERS, SEBASTIAN, VISSER, KIRSTEN, STUIJT, JEFFREY, DE GRAAF, CHRIS, STOCKS, MICHAEL, KELLAM, BARRIE, BRIDDON, STEPHEN, WIJTMANS, MAIKEL, DE ESCH, IWAN, HILL, STEPHEN and LEURS, ROB, 2019. MOLECULAR PHARMACOLOGY. 96(6), 737-752
  • ARRUDA MA, STODDART LA, GHERBI K, BRIDDON SJ, KELLAM B and HILL SJ, 2018. Frontiers in pharmacology. 8, 908
  • STODDART LA, VERNALL AJ, BOUZO-LORENZO M, BOSMA R, KOOISTRA AJ, DE GRAAF C, VISCHER HF, LEURS R, BRIDDON SJ, KELLAM B and HILL SJ, 2018. Scientific reports. 8(1), 1572
  • LAM R, GONDIN AB, CANALS M, KELLAM B, BRIDDON SJ, GRAHAM B and SCAMMELLS PJ, 2018. Journal of medicinal chemistry. (In Press.)
  • EMTAGE, ABIGAIL L., MISTRY, SHAILESH N., FISCHER, PETER M., KELLAM, BARRIE and LAUGHTON, CHARLES A., 2017. Journal of Biomolecular Structure & Dynamics. 35(12), 2604-2619
  • BAKER JG, GARDINER SM, WOOLARD J, FROMONT C, JADHAV GP, MISTRY SN, THOMPSON KS, KELLAM B, HILL SJ and FISCHER PM, 2017. FASEB Journal. 31(7), 3150-3166
  • SCHWEHM C, KELLAM B, GARCES AE, HILL SJ, KINDON ND, BRADSHAW TD, LI J, MACDONALD SJ, ROWEDDER JE, STODDART LA and STOCKS MJ, 2017. Journal of medicinal chemistry. 60(4), 1534-1554
  • DISNEY AJ, KELLAM B and DEKKER LV, 2016. ChemMedChem. 11(9), 972-9
  • SKILLING, K. J., KELLAM, B., ASHFORD, M., BRADSHAW, T. D. and MARLOW, M., 2016. SOFT MATTER. 12(43), 8950-8957
  • CONROY, SEAN, KINDON, NICHOLAS, KELLAM, BARRIE and STOCKS, MICHAEL J., 2016. JOURNAL OF MEDICINAL CHEMISTRY. 59(22), 9981-10005
  • STODDART, LEIGH A., VERNALL, ANDREA J., BRIDDON, STEPHEN J., KELLAM, BARRIE and HILL, STEPHEN J., 2015. NEUROPHARMACOLOGY. 98, 68-77
  • SCHWEHM, CAROLIN, LI, JIN, SONG, HONGMEI, HU, XIAO, KELLAM, BARRIE and STOCKS, MICHAEL J., 2015. ACS Medicinal Chemistry Letters. 6, 324-328
  • STONE, ERICA L., CITOSSI, FRANCESCA, SINGH, RAJINDER, KAUR, BALVINDER, GASKELL, MARGARET, FARMER, PETER B., MONKS, ANNE, HOSE, CURTIS, STEVENS, MALCOLM F. G., LEONG, CHEE-ONN, STOCKS, MICHAEL, KELLAM, BARRIE, MARLOW, MARIA and BRADSHAW, TRACEY D., 2015. BIOORGANIC & MEDICINAL CHEMISTRY. 23(21), 6891-6899
  • SCHEMBRI, LUKE S., STODDART, LEIGH A., BRIDDON, STEPHEN J., KELLAM, BARRIE, CANALS, MERITXELL, GRAHAM, BIM* and SCAMMELLS, PETER J.*, 2015. JOURNAL OF MEDICINAL CHEMISTRY. 58(24), 9754-9767
  • SCHWEHM, CAROLIN, LI, JIN, SONG, HONGMEI, HU, XIAO, KELLAM, BARRIE and STOCKS, MICHAEL J, 2015. Acs Medicinal Chemistry Letters. 6(3), 324-328
  • STONE, ERICA L, CITOSSI, FRANCESCA, SINGH, RAJINDER, KAUR, BALVINDER, GASKELL, MARGARET, FARMER, PETER B, MONKS, ANNE, HOSE, CURTIS, STEVENS, MALCOLM F G, LEONG, CHEE-ONN, STOCKS, MICHAEL, KELLAM, BARRIE, MARLOW, MARIA and BRADSHAW, TRACEY D, 2015. Bioorganic & medicinal chemistry. 23(21), 6891-6899
  • STODDART, LEIGH A, VERNALL, ANDREA J., BRIDDON, STEPHEN J, KELLAM, BARRIE and HILL, STEPHEN J, 2015. Neuropharmacology. 98, 68-77
  • SCHEMBRI, LUKE S, STODDART, LEIGH A, BRIDDON, STEPHEN J, KELLAM, BARRIE, CANALS, MERITXELL, GRAHAM, BIM and SCAMMELLS, PETER J, 2015. Journal of Medicinal Chemistry. 58(24), 9754-9767
  • VERNALL, ANDREA J., HILL, STEPHEN J. and KELLAM, BARRIE, 2014. BRITISH JOURNAL OF PHARMACOLOGY. 171(5), 1073-1084
  • STODDART, LEIGH A., KELLAM, BARRIE, BRIDDON, STEPHEN J. and HILL, STEPHEN J., 2014. BRITISH JOURNAL OF PHARMACOLOGY. 171(16), 3827-3844
  • HILL, STEPHEN J., MAY, LAUREN T., KELLAM, BARRIE and WOOLARD, JEANETTE, 2014. BRITISH JOURNAL OF PHARMACOLOGY. 171(5), 1102-1113
  • CORRIDEN R, KILPATRICK LE, KELLAM B, BRIDDON SJ and HILL SJ, 2014. FASEB journal. 28, 4211-4222
  • SKILLING, K. J., NDUNGU, A., KELLAM, B., ASHFORD, M., BRADSHAW, T. D. and MARLOW, M., 2014. JOURNAL OF MATERIALS CHEMISTRY B. 2(47), 8412-8417
  • SCHWEHM, CAROLIN, LEWIS, WILLIAM, BLAKE, ALEXANDER J., KELLAM, BARRIE and STOCKS, MICHAEL J., 2014. Acta Crystallographica Section C Structural Chemistry. 70, 1161-1168
  • SKILLING, K J, NDUNGU, A, KELLAM, BARRIE, ASHFORD, M, BRADSHAW, T D and MARLOW, M, 2014. J. Mater. Chem. B. 2(47), 8412-8417
  • HILL, STEPHEN J, MAY, LAUREN T, KELLAM, BARRIE and WOOLARD, JEANETTE, 2014. British journal of pharmacology. 171(5), 1102-1113
  • VERNALL, ANDREA J., HILL, STEPHEN J and KELLAM, BARRIE, 2014. British journal of pharmacology. 171(5), 1073-1084
  • SKILLING, KATHRYN J, CITOSSI, FRANCESCA, BRADSHAW, TRACEY D, ASHFORD, MARIANNE, KELLAM, BARRIE and MARLOW, MARIA, 2014. Soft Matter. 10(2), 237-256
  • STODDART, LEIGH A, KELLAM, BARRIE, BRIDDON, STEPHEN J and HILL, STEPHEN J, 2014. British journal of pharmacology. 171(16), 3827-3844
  • SCHWEHM, CAROLIN, LEWIS, WILLIAM, BLAKE, ALEXANDER J, KELLAM, BARRIE and STOCKS, MICHAEL J, 2014. Acta crystallographica. Section C, Structural chemistry. 70(Pt 12), 1161-1168
  • CORRIDEN, R., SELF, T., AKONG-MOORE, K., NIZET, V., KELLAM, B., BRIDDON, S.J. and HILL, S.J., 2013. EMBO Reports. 14(8), 726-732
  • MISTRY, S.N., BAKER, J.G., FISCHER, P.M., HILL, S.J., GARDINER, S.M. and KELLAM, B., 2013. Journal of Medicinal Chemistry. 56(10), 3852-3865
  • VERNALL AJ, STODDART LA, BRIDDON SJ, NG HW, LAUGHTON CA, DOUGHTY SW, HILL SJ and KELLAM B, 2013. Organic & biomolecular chemistry. 11(34), 5673-82
  • K. J. SKILLING, F. CITOSSI, T. D. BRADSHAW, M. ASHFORD, B. KELLAM and M. MARLOW, 2013. SOFT MATTER. 10(2), 237-256
  • DICKENS MP, ROXBURGH P, HOCK A, MEZNA M, KELLAM B, VOUSDEN KH and FISCHER PM, 2013. Bioorganic & medicinal chemistry. 21(22), 6868-77
  • VERNALL, A.J., STODDART, L.A., BRIDDON, S.J., HILL, S.J. and KELLAM, B., 2012. Journal of Medicinal Chemistry. 55(4), 1771-1782
  • DALE CL, HILL SJ and KELLAM B, 2012. MedChemComm. 3, 333-338
  • STODDART, L.A., VERNALL, A.J., DENMAN, J.L., BRIDDON, S.J., KELLAM, B. and HILL, S.J., 2012. Chemistry & Biology. 19(9), 1105-1115
  • BRIDDON, STEPHEN J, KELLAM, BARRIE and HILL, STEPHEN J, 2011. Methods in Molecular Biology. 746, 211-36
  • DEY, S., KELLAM, B., ALEXANDER, M.R., ALEXANDER, C. and ROSE, F.R.A.J., 2011. Journal of Materials Chemistry. 21(19), 6883-6890
  • BAKER, J.G., ADAMS, L.A., SALCHOW, K., MISTRY, S.N., MIDDLETON, R.J., HILL, S.J. and KELLAM, B., 2011. Journal of Medicinal Chemistry. 54(19), 6874-6887
  • JADHAV GP, CHHABRA SR, TELFORD G, HOOI DS, RIGHETTI K, WILLIAMS P, KELLAM B, PRITCHARD DI and FISCHER PM, 2011. Journal of Medicinal Chemistry. 54(9), 3348-3359
  • BAKER, J.G., MIDDLETON, R., ADAMS, L., MAY, L.T., BRIDDON, S.J., KELLAM, B. and HILL, S.J., 2010. British Journal of Pharmacology. 159(4), 772-786
  • CORDEAUX, Y., BRIDDON, S.J., ALEXANDER, S.P.H., KELLAM, B. and HILL, S.J., 2008. FASEB Journal. 22(3), 850-860
  • MIDDLETON,R, BRIDDON,S.J., CORDEAUX,Y., YATES,A.S., DALE,C.L., GEORGE,M., BAKER,J.G., HILL,S.J. and KELLAM,B., 2007. Journal of Medicinal Chemistry. 50(4), 782-793
  • CORDEAUX, Y., BRIDDON,S.J., ALEXANDER, S.P.H., KELLAM, B. and HILL, S.J., 2007. FASEB. Available at: <http://www.fasebj.org/papbyrecent.dtl>
  • DE BANK, P.A., HOU,Q., WARNER, R.M., WOOD, I.V., ALI, B.E., MACNEIL, S., KENDALL, D.A., KELLAM, B.K., SHAKESHEFF, K.M. and BUTTERY, L.D.K., 2007. Biotechnology and Bioengineering. 97(6), 1617-1625
  • YATES, A.S., DOUGHTY, S.W., KENDALL, D.A. and KELLAM, B., 2005. Bioorganic & Medicinal Chemistry Letters. 15(16), 3758-3762
  • ABUKHADER, M., HEAP, J., DE MATTEIS, C., KELLAM, B., DOUGHTY, S.W., MINTON, N. and PAOLI, M., 2005. Journal of Medicinal Chemistry. 48(24), 7714-7719
  • DE BANK, P. A., KELLAM, B., KENDALL, D. A. and SHAKESHEFF, K. M., 2005. JOURNAL OF MATERIALS CHEMISTRY. VOL 15, 2047-2055
  • KELLAM,B., WARD,PA.., RAHIM,A.S.A. and CHHABRA,S.R., 2005. Tetrahedron Letters. 46(10), 1703-1706
  • SEDMAN, V.L., ALLEN, S., CHAN, W.C., KELLAM, B. and TENDLER S.J.B., 2005. Functionalizing human amylin (20-29) fibrils FEBS Journal. 272, 517-518
  • ALI, BE, DE BANK, PA, KELLAM, B and SHAKESHEFF, KM, 2005. Controlled cell aggregation via cell-surface engineering International Journal of Experimental Pathology. 86(3), A21-A22
  • BRIDDON, S.J., MIDDLETON, R.J., CORDEAUX, Y., FLAVIN, F.M., WEINSTEIN, J.A., GEORGE, M.W., KELLAM, B. and HILL, S.J., 2004. Proceedings of the National Academy of Sciences of the United States of America. 101(13), 4673-4678
  • BRIDDON, S.J., MIDDLETON, R.J., YATES, A.S., GEORGE, M.W., KELLAM, B. and HILL, S.J., 2004. Faraday Discussions. 126, 197-207
  • SLEEMAN, MARK C, SMITH, PAUL, KELLAM, BARRIE, CHHABRA, SIRI RAM, BYCROFT, BARRIE W and SCHOFIELD, CHRISTOPHER J, 2004. ChemBioChem. 5(6), 879-82
  • QUIRK, R.A., KELLAM, B., BHANDARI, R.N., DAVIES, M.C., TENDLER, S.J.B. and SHAKESHEFF, K.M., 2003. Biotechnology and Bioengineering. 81(5), 625-628
  • DE BANK, P.A., KELLAM, B., KENDALL, D.A. and SHAKESHEFF, K.M., 2003. Biotechnology and Bioengineering. 81(7), 800-808
  • KELLAM, BARRIE, DE BANK, PAUL A and SHAKESHEFF, KEVIN M, 2003. Chemical Society Reviews. 32(6), 327-37
  • BYCROFT, B.W., CHHABRA, S.R., KELLAM, B. and SMITH, P., 2003. Tetrahedron Letters. 44(5), 973-976
  • CHHABRA, SIRI RAM, RAHIM, AISYAH S ABDUL and KELLAM, BARRIE, 2003. Mini Reviews in Medicinal Chemistry. 3(7), 679-87
  • SHAKESHEFF, K.M., SILVA, M., HOWDLE, S.M., SALEM, A.K., ROSE, F.R., WHITAKER, M.J., WOOD, I., DE BANK, P., KENDALL, D.A. and KELLAM, B., 2002. Delivering protein and cell therapeutics for tissue regeneration In: International Symposium on Recent Advances in Drug Delivery Systems.
  • SMITH, P., CHHABRA, S.R., KELLAM, B. and BYCROFT, B.W., 2002. Synthetic and biotransformations studies on trans-(3S, 5S)-1-carbapenam-3-carboxylic acid In: Third International Meeting. 33
  • CHHABRA, S. R., PAREKH, H., KHAN, A. N., BYCROFT, B. W. and KELLAM, B., 2001. Tetrahedron Letters. VOL 42(PART 11), 2189-2192
  • PAREKH, H., CHHABRA, S.R., BYCROFT, B.W. and KELLAM, B., 2001. Synthesis, evaluation and solid-phase applications of a Dde-based carboxy linker In: American Peptide Symposium. 145
  • WARD, P., CHHABRA, S.R. and KELLAM, B., 2001. Nsuper伪-Dmc protected amino acids: Hydrogenolysis and acid stable acceptors for 伪-glycosyl-1-O-amino acid synthesis In: American Peptide Symposium. P204
  • CHAN, W.C., BYCROFT, B.W. and KELLAM, B., 1998. Tetrahedron. 54, 6817-6832
  • CHHABRA, S.R., BYCROFT, B.W., KELLAM, B. and CHAN, W.C., 1997. Tetrahedron Letters. 38, 5391-5394
  • KELLAM, B., BYCROFT, B. W. and CHHABRA, S. R., 1997. Tetrahedron Letters. VOL 38(NUMBER 27), 4849-4852
  • DROUILLAT, B., KELLAM, B., DEKANY, G., STARR, M. S. and TOTH, I., 1997. Bioorganic and Medicinal Chemistry Letters. VOL 7(NUMBER 17), 2247-2250
  • KELLAM, B., CHAN, W.C., CHHABRA, S.R. and BYCROFT, B.W., 1997. Transient affinity tags based on the Dde protection/deprotection strategy: Synthesis and application of 2-biotinyl- and 2-hexanoyldimedone Tetrahedron Letters. 38(30), 5391-5394

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