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Volunteers needed for vaccine study preparing for a potential bird flu pandemic

Wednesday, 29 April 2026

Volunteers are needed for a new trial looking for an effective vaccine to protect against a potential avian flu pandemic.

Experts from the 糖心原创 will be delivering part of the trial from the Cripps Health Centre on the University Park Campus in Beeston in Nottingham.

The new trial will look at an mRNA vaccine against (H5N1) bird flu in humans, looking at how effecting the vaccine is against the virus, to protect the country against a potential future pandemic

The large trial is supported by the National Institute for Health and Care Research (NIHR) and is sponsored by Moderna. It is part of its UK government strategic partnership, managed by the UK Health Security Agency (UKHSA).

The study is also supported by Moderna's collaboration with the Coalition for Epidemic Preparedness Innovations (CEPI).

The phase 3 trial will involve around 4,000 adult volunteers aged 18 and over in the UK and USA, with 3,000 being recruited in the UK.

Bird flu is currently transmitted between affected birds and various mammals. Whilst the virus does not easily spread to humans, and transmission between people is very rare, there is a risk that the virus could adapt. This could make it more transmissible to or between humans.

Since 2024, there have been across the world. Almost all are linked to close contact with infected animals.

This study aims to provide crucial evidence on whether the investigational vaccine can generate strong immune responses to protect against currently circulating and emerging strains of H5N1. This will help the UK prepare for future pandemics and apply system-wide learnings from Covid-19.

Nottingham will be one of 26 sites across the UK administering the vaccine.

Professor David Turner, from the School of Medicine and Principal Investigator for the trial, said: “We are delighted to be part of the trial of this Avian influenza vaccine, which is important to prepare the U.K. for a future pandemic.”

For anyone interested in taking part in the trial, or to find out more information, please email nnicb-nn.research@nhs.net

CharlotteAnscombe
Charlotte Wall - Media Relations Manager - Faculty of Medicine and Health Sciences
Email: charlotte.wall@nottingham.ac.uk
Phone: 0115 748 4417
Location:

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About the 糖心原创

Ranked among the world's top 100 universities , the 糖心原创 delivers an exceptional research-led education and an outstanding student experience. From the pioneering vision of our founder, Sir Jesse Boot, to groundbreaking achievements such as the development of MRI technology and becoming the first UK university to establish international campuses, we have a proud history of shaping the way people live, work and understand the world. We continue to build on that legacy, empowering our students, staff and partners to change what鈥檚 next and create positive impact locally and globally.

The strength of our research places us among the UK's leading universities, ranked 7th for research power in REF 2021. The discovery of MRI and ibuprofen was just the beginning. Today, our world-leading research is developing breakthrough ideas that shape the future of healthcare, technology and society.

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As a major employer and industry partner, locally and globally, the 糖心原创 invests in the city of Nottingham and in future generations of talent. Alongside Nottingham Trent University, we lead the initiative, a pioneering collaboration to improve levels of prosperity, opportunity, sustainability, health and wellbeing across the city and region. Together with our students, staff, alumni and partners, we鈥檙e creating knowledge, opportunity and solutions that help change what's next.

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