糖心原创

Contact

• workRoom Room 4045 Division of Medical Sciences & Graduate Entry Medicine
  Royal Derby Hospital
  Uttoxeter Road
  Derby
  DE22 3DT
  UK
• work01332 724738
• fax01332 724626
• wayne.carter@nottingham.ac.uk

Biography

Dr Wayne Grant Carter completed a BSc (Hons) degree in Biochemistry with Nutrition and then a PhD in Biochemistry at the University of Southampton. He subsequently undertook post-doctoral research posts at The Babraham Institute, Cambridge; Imperial College, London; University of California at Irvine, USA, and then at the University of Oxford. Additionally, Dr Carter has worked for a global reagent supplier, Sigma, a SME company, Mobious Genomics, and has been employed as a consultant for Syngenta. Dr Carter is currently an Associate Professor and Group Leader (Clinical Toxicology Research Lab) within the School of Medicine, 糖心原创. Dr Carter's research interests are varied and include the detection and utilization of novel biomarkers of toxicological exposure. Dr Carter is an elected Fellow of the Royal Society of Chemistry (FRSC).

Expertise Summary

Understanding the molecular mechanisms that underpin disease provides the basis for targeted therapeutics. The research in my lab is concerned with understanding protein changes and modifications that can trigger pathology. In recent years we have focussed on hepato- and neuro-toxicological mechanisms. We employ cell and animal models and human postmortem tissue to understand pathological changes and utilize a broad range of biological and biochemical techniques to study disease. Current projects include the biological impact of environmental pesticides and heavy metals, liver and brain toxicity of alcohol, mechanisms that trigger protein aggregation in neurodegenerative diseases, and purification and assessment of the beneficial properties of phytochemicals including their actions as neuroprotective and anti-cancer agents.

Teaching Summary

University Teaching and Teaching-related Activities:

• Course Director for the BSc (Hons) Medical Physiology and Therapeutics (MPT) degree.
• Current or previous Module Convenor and Assessments Lead: Clinical Toxicology Studies (Medicine, BMBS); Cancer Biology (BSc, Medical Physiology & Therapeutics (MPT) degree); Immunology (BSc, MPT degree); Clinical Toxicology (BSc, MPT degree). Cellular Disease (BSc, MPT).
• Module Contributor: Range of BMBS and BSc modules.
• Academic Unit 3, Co-Lead and Derby Homebase Lead: BMedSci program.
• Senior Tutor: BMBS Graduate Entry Medicine and Foundation Medicine and MPT degrees (2010-present).
• Admissions Lead & Widening Participation Lead: MPT degree (2011-present).
• School of Medicine Alumni Lead (2018-2023).

Selected Publications

• VIGNESWARA, V., CASS, S., WAYNE, D., BOLT, E.L., RAY, D.E. and CARTER, W.G., 2013. PLoS ONE. 8(4), e61442
• LEGGATE, M., CARTER, W.G., EVANS, M.J.C., VENNARD, R.A., SRIBALA-SUNDARAM, S. and NIMMO, M.A., 2012. Journal of Applied Physiology. 112(8), 1353-1360
• TARHONI, M.H., VIGNESWARA, V., SMITH, M., ANDERSON, S., WIGMORE, P., LEES, J.E., RAY, D.E. and CARTER, W.G., 2011. Molecules. 16(10), 8535-8551
• CARTER, W.G., TARHONI, M.H. and RAY, D.E., 2010. Journal of Chromatography B. 878(17-18), 1312-1319

• View all publications

• SHERIF MA, CARTER WG and MELLOR IR, 2025. Journal of Xenobiotics. 2025(15), 12
• WIJESEKARA A, WIJAMUNIGE BC and CARTER WG, 2025. In: Young Scientist Forum (YSF) National Science and Technology Commission Sri Lanka YSF Thematic Publication- 2025.
• ALMUNTASHIRI N, EL SHARAZLY BM and CARTER WG, 2025. Biomolecules. 15(6), 816
• KOCON A, SMITH SJ, MORENTIN B, CALLADO LF, CARTER WG and RAHMAN R, 2025. Scientific Reports. 15, 24021
• ALJADAAN, ADEL M., ALSAADI, AYMAN M., SHAIKH, IBRAHIM A., WHITBY, ALISON, RAY, ARUNDHATI, KIM, DONG-HYUN and CARTER, WAYNE G., 2025. Biomedicines. 13(9),
• ALNASSER MN, MALIK N, AHMED A, NEWMAN A, MELLOR IR and CARTER WG, 2025. Brain Sciences. 15(10), 1073
• WIJESEKARA A, WIJAMUNIGE BC, KOCON A, MELLOR IR and CARTER WG, 2025. Applied Sciences. 15(19), 10800
• EL SHARAZLY BM, AHMED A, ELSHEIKHA HM and CARTER WG, 2024. Biomedicines. 12, 505
• MUDYANSELAGE AW, WIJAMUNIGE BC, KOCON A, TURNER R, MCLEAN D, MORENTIN B, CALLADO LF and CARTER WG, 2024. Antioxidants. 13(5), 580
• ASHRAF A, AHMED A, JUFFER A and CARTER WG, 2024. Brain Sciences. 14(6), 545
• BADAWI K, EL SHARAZLY BM, NEGM O, KHAN R and CARTER WG, 2024. Antioxidants. 13(8), 932
• NASEEM A, RASOOL F, HAASHMI FK, SHOAIB MH and CARTER WG, 2024. F1000Research. 13, 1241
• NAWAZ R, HUSNAIN A, ALI MA, HASSAN Z, AHAD A, AMAT-UR-RASOOL H, SHAHID M, MEHMOOD U, RAZZAQ A, IDREES M and CARTER WG, 2024. F1000Research. 13, 1292
• LAPPIN O and CARTER WG, 2024. The Biochemist (London). 46(5), 35-36
• EL SHARAZLY BM, ABOUL ASAAD IA, YASSEN NA, EL MAGHRABY GM, CARTER WG, MOHAMED DA, AMER BS and ISMAIL HIH, 2023. Acta Tropica. 239, 106810
• ALNASSER MN, ALSAADI AM, WHITBY A, KIM D-H, MELLOR IR and CARTER WG, 2023. Life. 13(4), 1019
• MUDYANSELAGE AW, WIJAMUNIGE BC, KOCON A and CARTER WG, 2023. Brain Sciences. 13, 728
• RODGER AT, ALNASSER MN and CARTER WG, 2023. International Journal of Molecular Sciences. 24(13), 11022
• ELMORSY E, AL-GHAFARI A, AL DOGHAITHER H, HASHISH S, SALAMA M, MUDYANSELAGE AW, JAMES L and CARTER WG, 2023. Brain Sciences. 13, 1717
• AMAT-UR-RASOOL H, AHMED M, HASNAIN S, AHMED A and CARTER WG, 2022. Current Issues in Molecular Biology.. 44(1), 152-175
• AMAT-UR-RASOOL H, LATIF A, YASMEEN A, SHAHID N, AZAM S, BASHIR A, HUSNAIN T, RAO AQ, CARTER WG and SHAHID AA, 2022. Molecular Biology Reports.
• ALSAADI A and CARTER WG, 2022. European Pharmaceutical Review. 27(2), 2-4
• AL-NASSER M, MELLOR I and CARTER WG, 2022. Brain Sciences. 12(5), 577
• ALI UA, IFTIKHAR N, AMAT-UR-RASOOL H, AHMED M, HAFEEZ J and CARTER WG, 2022. Healthcare. 2022(10), 1049
• ELMORSY E, AL-GHAFARI A, AL DOGHAITHER H, SALAMA M and CARTER WG, 2022. Brain Sciences. 12(8), 975
• ALNASSER MN, MELLOR IR and CARTER WG, 2022. Molecules. 27(15), 4891
• NASEEM A, RASOOL F, AHMED A and CARTER WG, 2022. Current Issues in Molecular Biology.. 45(1), 12-32
• AMAT-UR-RASOOL, H., AHMED, M., HASNAIN, S. and CARTER, W.G., 2021. Brain Sciences. 11, 184
• PRAKASH, S and CARTER WG, 2021. Brain Sciences. 11, 1573
• SCHAFFERT L.-N and CARTER WG, 2021. . In: R. BAWA and G.F. ANDETTE, eds., Advances in Medical Biochemistry, Genomics, Physiology, and Pathology. Ist Edition. Jenny Stanford Publishing.
• SCHAFFERT, L-N and CARTER, W.G., 2020. Brain Sciences. 10(4), 232
• ALELWANI W, ELMORSY E, KATTAN SW, BABTEEN NA, ALNAJEEBI AM, AL-GHAFARI A and CARTER WG, 2020. Toxicology letters. 333, 184-191
• AMAT-UR-RASOOL H, SYMES F, TOOTH D, SCHAFFERT L-N, ELMORSY E, AHMED M, HASNAIN S and CARTER WG, 2020. Biomolecules. 10, 1556
• CARTER WG, 2020. Dead as a Dodo The Biochemist. 42, 50-50
• NWIDU LL, ALIKWE PCN, ELMORSY E and CARTER WG, 2019. Medicines. 6(15),
• AL-GHAFARI A, ELMORSY E, FIKRY E, ALROWAILI M and CARTER WG, 2019. PLoS One. 14(11), e0225341
• DORLING JL, CLAYTON DJ, JONES J, CARTER WG, THACKRAY AE, KING JA, PUCCI A, BATTERHAM RL and STENSEL DJ, 2019. Am J Clin Nutr. 110(5), 1055-1066
• NWIDU LL, OBOMA YI, ELMORSY E and CARTER WG, 2018. Journal of Taibah University Medical Sciences. 13(4), 344-354
• NWIDU LL, ELMORSY E, APRIOKU JS, SIMINIALAYI I and CARTER WG, 2018. Medicines (Basel). 5(3), pii; E71
• NWIDU LL, ELMORSY E and CARTER WG, 2018. Malays J Med Sci. 25(2), 27-39
• NWIDU LL, ELMORSY E, OBOMA YI and CARTER WG, 2018. Journal of Taibah University Medical Sciences. 13(3), 262-271
• LABISSO WL, RAULIN AC, NWIDU LL, KOCON A, WAYNE D, ERDOZAIN AM, MORENTIN B, SCHWENDENER D, ALLEN G, ENTICOTT J, GERDES HK, JOHNSON L, GRZESKOWIAK J, DRIZOU F, TARBOX R, OSNA NA, KHABANDA KK, CALLADO LF and CARTER WG, 2018. Brain Sci. 8(9), pii E175
• NWIDU LL, OBOMA YI, ELMORSY E and CARTER WG, 2018. Journal of Basic and Clinical Physiology and Pharmacology. 29(6), 609-619
• ELMORSY E, ATTALLA SM, FIKRY E, KOCON A, TURNER R, CHRISTIE D, WARREN A, NWIDU LL and CARTER WG, 2017. Human & Experimental Toxicology. 36, 616-625
• NWIDU LL, ELMORSY E, THORNTON J, WIJAMUNIGE B, WIJESEKARA A, TARBOX R, WARREN A and CARTER WG, 2017. Pharmaceutical Biology. 55(1), 1875-1883
• ELMORSY E, AL-GHAFARI A, ALMUTAIRI FM, AGGOUR AM and CARTER WG, 2017. Toxicol In Vitro. 44, 154-163
• CARTER WG, 2017. An answer to Alzheimer鈥檚? Health. 2, 88-89
• OSNA NA, CARTER WG, GANESAN M, KIRPICH IA, MCCLAIN CJ, PETERSEN DR, SHEARN CT and TOMASI ML, 2016. World J Gastroenterol. 22(27), 6192-6200
• CARTER WG, VIGNESWARA V, NEWLACZYL A, WAYNE D, AHMED B, SADDINGTON S, BREWER C, RAUT N, GERDES HK, ERDOZAIN AM, TOOTH D, BOLT EL, OSNA NA and TUMA DJ, 2015. Isoaspartate, Carbamoyl phosphate synthase-1, and Carbonic anhydrase-III as biomarkers of liver injury. Biochemical and Biophysical Research Communications. 498, 626-631
• ERDOZAIN AM, MORENTIN B, BEDFORD L, KING E, TOOTH D, BREWER C, WAYNE D, JOHNSON L, GERDES HK, WIGMORE P, CALLADO LF and CARTER WG, 2014. PloS one. 9(4), e93586
• VIGNESWARA, V., CASS, S., WAYNE, D., BOLT, E.L., RAY, D.E. and CARTER, W.G., 2013. PLoS ONE. 8(4), e61442
• ALEXANDER SPH, BENSON HE, FACCENDA E, PAWSON AJ, SHARMAN JL, MCGRATH JC, CATTERALL WA, SPEDDING M, PETERS JA, HARMAR AJ, CGTP COLLABORATORS, ABUL-HASN N, ANDERSON CM, ANDERSON CMH, ARAIKSINEN MS, ARITA M, ARTHOFER E, BARKER EL, BARRATT C, BARNES NM, BATHGATE R, BEART PM, BELELLI D, BENNETT AJ, BIRDSALL NJM, BOISON D, BONNER TI, BRAILSFORD L, BR脰ER S, BROWN P, CALO G, CARTER WG, CATTERALL WA, CHAN SLF, CHAO MV, CHIANG N, CHRISTOPOULOS A, CHUN JJ, CIDLOWSKI J, CLAPHAM DE, COCKCROFT S, CONNOR MA, COX HM, CUTHBERT A, DAUTZENBERG FM, DAVENPORT AP, DAWSON PA, DENT G, DIJKSTERHUIS JP, DOLLERY CT, DOLPHIN AC, DONOWITZ M, DUBOCOVICH ML, EIDEN L, EIDNE K, EVANS BA, FABBRO D, FAHLKE C, FARNDALE R, FITZGERALD GA, FONG TM, FOWLER CJ, FRY JR, FUNK CD, FUTERMAN AH, GANAPATHY V, GAISNIER B, GERSHENGORN MA, GOLDIN A, GOLDMAN ID, GUNDLACH AL, HAGENBUCH B, HALES TG, HAMMOND JR, HAMON M, HANCOX JC, HAUGER RL, HAY DL, HOBBS AJ, HOLLENBERG MD, HOLLIDAY ND, HOYER D, HYNES NA, INUI K, ISHII S, JACOBSON KA, JARVIS GE, JARVIS MF, JENSEN R, JONES CE, JONES RL, KAIBUCHI K, KANAI Y, KENNEDY C, KERR ID, KHAN AA, KLIENZ MJ, KUKKONEN JP, LAPOINT JY, LEURS R, LINGUEGLIA E, LIPPIAT J, LOLAIT SJ, LUMMIS SCR, LYNCH JW, MACEWAN D, MAGUIRE JJ, MARSHALL IL, MAY JM, MCARDLE CA, MCGRATH JC, MICHEL MC, MILLAR NS, MILLER LJ, MITOLO V, MONK PN, MOORE PK, MOORHOUSE AJ, MOUILLAC B, MURPHY PM, NEUBIG RR, NEUMAIER J, NIESLER B, OBAIDAT A, OFFERMANNS S, OHLSTEIN E, PANARO MA, PARSONS S, PWRTWEE RG, PETERSEN J, PIN J, POYNER DR, PRIGENT S, PROSSNITZ ER, PYNE NJ, PYNE S, QUIGLEY JG, RAMACHANDRAN R, RICHELSON EL, ROBERTS RE, ROSKOSKI R, ROSS RA, ROTH M, RUDNICK G, RYAN RM, SAID SI, SCHILD L, SANGER GJ, SCHOLICH K, SCHOUSBOE A, SCHULTE G, SCHULZ S, SERHAN CN, SEXTON PM, SIBLEY DR, SIEGEL JM, SINGH G, SITSAPESAN R, SMART TG, SMITH DM, SOGA T, STAHL A, STEWART G, STODDART LA, SUMMERS RJ, THORENS B, THWAITES DT, TOLL L, TRAYNOR JR, USDIN TB, VANDENBERG RJ, VILLALON C, VORE M, WALDMAN SA, WARD DT, WILLARS GB, WONNACOTT SJ, WRIGHT E, YE RD, YONEZAWA A and ZIMMERMANN M, 2013. British journal of pharmacology. 170(8), 1449-58
• LEGGATE, M., CARTER, W.G., EVANS, M.J.C., VENNARD, R.A., SRIBALA-SUNDARAM, S. and NIMMO, M.A., 2012. Journal of Applied Physiology. 112(8), 1353-1360
• CARTER WG, 2012. Medicinal Chemistry. S11, 002
• CARTER WG, 2012. Medicinal Chemistry. S11, 001
• TARHONI, M.H., VIGNESWARA, V., SMITH, M., ANDERSON, S., WIGMORE, P., LEES, J.E., RAY, D.E. and CARTER, W.G., 2011. Molecules. 16(10), 8535-8551
• CARTER, W.G., TARHONI, M.H. and RAY, D.E., 2010. Journal of Chromatography B. 878(17-18), 1312-1319
• KHARBANDA, K.K., VIGNESWARA, V., MCVICKER, B.L., NEWLACZYL, A.U., BAILEY, K., TUMA, D., RAY, D.E. and CARTER, W.G., 2009. Biochemical and Biophysical Research Communications. 381(4), 523-527
• TARHONI, MABRUKA H, LISTER, TIMOTHY, RAY, DAVID E and CARTER, WAYNE G, 2008. Biomarkers. 13(4), 343-63
• CARTER, W.G. and ASWAD, D.W., 2008. Biochemistry. 47(40), 10757-10764
• JETHWA, P.H., WARNER, A., NILAWEERA, K.N., BRAMELD, J.M., KEYTE, J.W., CARTER, W.G., BOLTON, N., BRUGGRABER, M., MORGAN, P.J., BARRETT, P. and EBLING, F.J.P., 2007. Endocrinology. 148(8), 4044-4055
• CARTER, WAYNE G, TARHONI, MABRUKA, RATHBONE, ALEXANDRA J and RAY, DAVID E, 2007. Human and Experimental Toxicology. 26(4), 347-54
• SKAMARAUSKAS, J, CARTER, W, FOWLER, M, MADJD, A, LISTER, T, MAVROUDIS, G and RAY, D E, 2007. Toxicology. 232(3), 268-76
• VIGNESWARA, V., LOWENSON, J.D., POWELL, C.D., THAKUR, M., BAILEY, K., CLARKE, S., RAY, D.E. and CARTER, W.G, 2006. The Journal of biological chemistry. 281(43), 32619-32629
• YOUNG, A L, CARTER, W G, DOYLE, H A, MAMULA, M J and ASWAD, D W, 2001. Journal of Biological Chemistry. 276(40), 37161-5
• FINCH, A, DAVIS, W, CARTER, W G and SAKLATVALA, J, 2001. Biochemical Journal. 353(Pt 2), 275-81
• CARTER, W G, SULLIVAN, A C, ASAMOAH, K A and SALE, G J, 1996. Biochemistry. 35(45), 14340-51
• ASAMOAH, K A, ATKINSON, P G, CARTER, W G and SALE, G J, 1995. Studies on an insulin-stimulated insulin receptor serine kinase activity: separation of the kinase activity from the insulin receptor and its reconstitution back to the insulin receptor. Biochemical Journal. 308 ( Pt 3), 915-22
• CARTER, W G, ASAMOAH, K A and SALE, G J, 1995. Biochemistry. 34(29), 9488-99