糖心原创

Contact

• workRoom WE1379 E floor West Block
  Queen's Medical Centre
  Nottingham
  NG7 2UH
  UK
• work0115 82 31151
• jane.grove@nottingham.ac.uk

Biography

ORCiD:0000-0002-9950-7201

I am an Associate Professor in the Hepatology Group in the Nottingham Digestive Diseases Centre in Translational Medical Sciences and the Gastrointestinal and Liver Disorders Theme of the NIHR Nottingham Biomedical Research Centre. My research includes translational research projects in the following areas:

• Drug-induced liver injury (assessment, genetic and environmental factors that affect drug metabolism and hepatotoxicity).
• Non-alcoholic fatty liver disease and alcoholic liver disease (mechanisms and biomarkers of liver injury including microbiome and metabolomics).
• Genetic determinants of liver disease.
• Development and validation of markers of oxidative stress in the evaluation of acute liver injury and chronic liver diseases.
• Non-invasive assessment of liver fibrosis.
• Clinical application of liver biomarkers.
• Experimental diagnostics of chronic liver injury.

IMI TransBioLine Consortium Research: The TransBioLine project aims to develop novel safety biomarkers that will reliably indicate injury of the liver, kidneys, pancreas, blood vessels, and central nervous system for drug development purposes. By the end of the project, the team will have set up an infrastructure and processes to continue biomarker research across a comprehensive network of industry, academic institutions, and small and medium-sized enterprises, providing to the scientific community, industry and patients with detailed data across a large spectrum of advanced safety biomarkers. (www.Transbioline.com)

I am co-leader for work group 1 of COST ACTION CA17112 - PRO-EURO DILI NETWORK https://www.cost.eu/actions/CA17112

I am involved in collaborative research partnerships with Population Health and Research Institute, Trivandrum, India. ClinicalTrials.gov Identifier: NCT03844165 - Fighting Fatty Liver in India.

I also contributed to the Nottingham Molecular Pathology Node (http://www.nmpn.info/).

Current research studies recruiting participants:

Fatty Liver and Steatohepatitis 糖心原创-

This study evaluates possible genetic reasons for the development of non-alcoholic steatohepatitis (NASH), alcoholic steatohepatitis (ASH) and the progression of fatty liver.

Methotrexate 糖心原创-

This study investigates the effectiveness of certain non-invasive tests in the detection of liver scarring in patients with rheumatoid arthritis or psoriasis who are currently on methotrexate.

Drug-induced Liver Injury 糖心原创-

This is an international Biobank resource to enable research into the causes and characteristics of drug-induced liver injury (DILI) so that new, non-invasive diagnostic tests can be developed. The goal is to predict and prevent drug-induced liver injury (DILI) so patients can be safely treated with medications they need.

Checkpoint Inhibitor-induced Liver Injury (ChILI) - ClinicalTrials.gov Identifier: NCT04476563:

Multi-center prospective observational study to identify the incidence and risk factors for checkpoint inhibitor-induced liver injury and characterize biochemical, genetic, immunological, and histological features associated with it.

Low GI Diet Effects on Non-Alcoholic Fatty Liver Disease (LGI-NAFLD) 糖心原创 - ClinicalTrials.gov Identifier: NCT04415632.

A 2 x 2 cross-over dietary intervention trial designed to investigate the effects of low glycemic index (LGI) versus high glycemic index (HGI) diet on hepatic fat accumulation and gut microbiota composition in participants with NAFLD.

NDDCBRU Research Tissue Bank-

Nottingham Digestive Diseases Centre Biomedical Research Unit research tissue bank is a local collection of biological samples from patients and research participants to facilitate new research projects investigating digestive health. The aim is to provide high quality biological samples to researchers worldwide for projects to improve the health and care of patients in the future.

Responsibilities:

I am academic lead for postgraduate student training and development in the School of Medicine and a member of the Doctoral Training Committee.

I am the Human Tissue Authority Person Designate for the Nottingham Digestive Diseases Centre and academic representative on the University Biosafety Committee and School of Medicine Safety Committee. (I have Biosafety Practitioner 1 qualification).

I am a member of the UK Stratified Medicine and Pharmacogenetics Committee and am involved in developing Biobank networks.

Research Experience:

Analysis of genetic determinants of the development of alcoholic liver disease. (Newcastle University)

Improvement of E. coli nitroreductase by mutagenesis: a route to optimization of virus- directed enzyme-prodrug cancer therapy. (Cobra Therapeutics)

DNA double-strand break repair in E. coli. (Nottingham University)

Role of novel Type IV secretion systems in Helicobacter pylori virulence. (Nottingham University)

Degree: Molecular Biology and Biochemistry (Durham University)

PGCE: secondary science (糖心原创) & Qualified Teacher Status

PhD: Escherichia coli genes essential for formate-dependent nitrite reduction, cytochrome c biosynthesis and periplasmic nitrate reduction. (Birmingham University)

Expertise Summary

Quantification of circulating biomarkers including Luminex multiplex analysis on Bioplex 200

Characterisation and phenotyping of patient cohorts and analysis of clinical data

Expression analyses including assessment of liver tissue markers

Molecular genetics including detection of polymorphisms, cloning, PCR and sequencing

Biochemistry (including protein expression, purification and analysis)

Biobanking: setting up a Research Tissue Bank, clinical sample collection, storage and cataloging/databases

Microbiology: specialist in E.coli and H.pylori manipulation and phenotyping

Research Summary

My research includes translational research projects in the following areas:

• Drug-induced liver injury (assessment, genetic and environmental factors that affect drug metabolism and hepatotoxicity).
• Non-alcoholic fatty liver disease and alcoholic liver disease (mechanisms and biomarkers of liver injury).
• Genetic determinants of liver disease.
• Development and validation of markers of oxidative stress in the evaluation of acute liver injury and chronic liver diseases.
• Non-invasive assessment of liver fibrosis.
• Clinical application of liver biomarkers.
• Experimental diagnostics of chronic liver injury.

Research Experience:

Analysis of genetic determinants of the development of alcoholic liver disease. (Newcastle University)

Improvement of E. coli nitroreductase by mutagenesis: a route to optimization of virus- directed enzyme-prodrug cancer therapy. (Cobra Therapeutics)

DNA double-strand break repair in E. coli. (Nottingham University)

Role of novel Type IV secretion systems in Helicobacter pylori virulence. (Nottingham University)

Degree: Molecular Biology and Biochemistry (Durham University)

PhD: Escherichia coli genes essential for formate-dependent nitrite reduction, cytochrome c biosynthesis and periplasmic nitrate reduction. (Birmingham University)

.

Selected Publications

• ASTBURY, S, GROVE JI, DORWARD DA, GUHA IN and FALLOWFIELD JA, 2021. J Pathol Clin Res. Sep;7(5), 471-481
• NICOLETTI P, DEVARBHAVI H, GOEL A, VENKATESAN R, EAPEN CE, GROVE JI, ZAFER S, BJORNSSON E, LUCENA MI, ANDRADE RJ, PIRMOHAMED M, WADELIUS M, LARREY D, LARREY D, IBANEZ L, WATKINS PB, DALY AK and AITHAL GP, 2021. Clin Pharmacol Ther. 109(4), 1125-1135
• ATKINSON, STEPHEN R, GROVE, JANE I, LIEBIG, STEPHANIE, ASTBURY, STUART, VERGIS, NIKHIL, GOLDIN, ROBERT, QUAGLIA, ALBERTO, BANTEL, HEIKE, GUHA, INDRA NEIL, THURSZ, MARK R, NEWCOMBE, PAUL, STRNAD, PAVEL and AITHAL, GURUPRASAD P, 2020. The American Journal of Gastroenterology. 115(11), 1857-1868
• STICKEL, FELIX, LUTZ, PHILIPP, BUCH, STEPHAN, NISCHALKE, HANS DIETER, SILVA, INES, RAUSCH, VANESSA, FISCHER, JANETT, WEISS, KARL HEINZ, GOTTHARDT, DANIEL, ROSENDAHL, JONAS, MAROT, ASTRID, ELAMLY, MONA, KRAWCZYK, MARCIN, CASPER, MARKUS, LAMMERT, FRANK, BUCKLEY, THOMAS WM, MCQUILLIN, ANDREW, SPENGLER, ULRICH, EYER, FLORIAN, VOGEL, ARNDT, MARHENKE, SILKE, VON FELDEN, JOHANN, WEGE, HENNING, SHARMA, ROHINI, ATKINSON, STEPHEN, FRANKE, ANDRE, NEHRING, SOPHIE, MOSER, VINCENT, SCHAFMAYER, CLEMENS, SPAHR, LAURENT, LACKNER, CAROLIN, STAUBER, RUDOLF E., CANBAY, ALI, LINK, ALEXANDER, VALENTI, LUCA, GROVE, JANE I., AITHAL, GURUPRASAD P., MARQUARDT, JENS U., FATEEN, WALEED, ZOPF, STEFFEN, DUFOUR, JEAN-FRANCOIS, TREBICKA, JONEL, DATZ, CHRISTIAN, DELTENRE, PIERRE, MUELLER, SEBASTIAN, BERG, THOMAS, HAMPE, JOCHEN and MORGAN, MARSHA Y, 2020. Hepatology. 72(1), 88-102

• View all publications

Past Research

MRC-funded Nottingham Molecular Pathology Node (http://www.nmpn.info/): The Nottingham Molecular Pathology Node for Integrated Multi-platform Biomarker Research and Knowledge Transfer -bringing together informatics, computational modeling and molecular pathology to find new biomarkers for a range of diseases, particularly those affecting the digestive and respiratory systems and the liver.

Role of novel Type IV secretion systems in Helicobacter pylori virulence. (PI Rob Delahay)

DNA double-strand break repair in E. coli. (PI Bob Lloyd)

• GROVE J.I., LO P., SHRINE N., BARWELL J., WAIN L., TOBIN M., ANDREW M. SALTER, HANON N.R.F., AITHAL G.P. and ET AL., 2023. JHEP Reports.
• EDMOND ATALLAH, JANE I. GROVE, COLIN CROOKS, ESTHER BURDEN-TEH, ABHISHEK ABHISHEK, SULLEMAN MOREEA, KELSEY M. JORDAN, AFTAB ALA, DAVID HUTCHINSON, RICHARD J. ASPINALL, RUTH MURPHY and GURUPRASAD P. AITHAL, 2023. Journal of Hepatology. 78(5), 989-997
• JANE I. GROVE, PEGGY C.K. LO, NICK SHRINE, JULIAN BARWELL, LOUISE V. WAIN, MARTIN D. TOBIN, ANDREW M. SALTER, ADITI N. BORKAR, SARA CUEVAS-OCA脩A, NEIL BENNETT, CATHERINE JOHN, IOANNA NTALLA, GABRIELA E. JONES, CHRISTOPHER P. NEAL, MERVYN G. THOMAS, HELEN KUHT, PANKAJ GUPTA, VISHWARAJ M. VEMALA, ALLISTER GRANT, ADEOLU B. ADEWOYE, KOTACHERRY T. SHENOY, LEENA K. BALAKUMARAN, EDWARD J. HOLLOX, NICHOLAS R.F. HANNAN and GURUPRASAD P. AITHAL, 2023. JHEP Reports. 5(8), 100764
• GAI, ZHIBO, SAMODELOV, SOPHIA L., ALECU, IRINA, HORNEMANN, THORSTEN, GROVE, JANE I., AITHAL, GURUPRASAD P., VISENTIN, MICHELE and KULLAK-UBLICK, GERD A., 2023. International Journal of Molecular Sciences. 24(3),
• L脴NSMANN, IDA, GROVE, JANE I., HAIDER, ASMA, KAYE, PHILIP, KARSDAL, MORTEN A., LEEMING, DIANA J. and AITHAL, GURUPRASAD P., 2023. Biology. 12(8),
• HASHIM, AHMED, BREMNER, STEPHEN, GROVE, JANE I, ASTBURY, STUART, MENGOZZI, MANUELA, O鈥橲ULLIVAN, MARGARET, MACKEN, LUCIA, WORTHLEY, TIM, KATAREY, DEV, AITHAL, GURUPRASAD P and OTHERS, 2022. Liver International. 42(3), 628-639
• RAHMAN SR, ROPER JA, GROVE JI, AITHAL GP and BENNETT AJ, 2022. Liver International. 42(3), 507-521
• INNES H, WALKER AJ, BENSELIN J, GROVE JI, PEDERGNANA V, AZIM ANSARI M, LIN SK, MCLAUCHLAN J, HUTCHINSON SJ, BARNES E, IRVING WL, GUHA IN and STOP-HCV CONSORTIA, 2022. Clin Transl Gastroenterol.. Feb 9;13(3):e00462,
• VIJAY A, AL-AWADI A, CHALMERS J, BALAKUMARAN L, GROVE JI, VALDES AM, TAYLOR MA, SHENOY KT and AITHAL GP, 2022. Nutrients.
• BJ脰RNSSON ES, STEPHENS C, ATALLAH E, ROBLES-DIAZ M, ALVAREZ-ALVAREZ I, GERBES A, WEBER S, STIRNIMANN G, KULLAK-UBLICK G, CORTEZ-PINTO H, GROVE JI, LUCENA MI, ANDRADE RJ and AITHAL GP, 2022.
• ASTBURY, S, GROVE JI, DORWARD DA, GUHA IN and FALLOWFIELD JA, 2021. J Pathol Clin Res. Sep;7(5), 471-481
• SCOTT RA, WILLIAMS HG, HOAD CL, ALYAMI A, ORTORI CA, GROVE JI, MARCIANI L, MORAN GW, MENYS A and AITHAL GP, 2021. J Magn Reson Imaging. 53(5), 1422-1431
• NICOLETTI P, DEVARBHAVI H, GOEL A, VENKATESAN R, EAPEN CE, GROVE JI, ZAFER S, BJORNSSON E, LUCENA MI, ANDRADE RJ, PIRMOHAMED M, WADELIUS M, LARREY D, LARREY D, IBANEZ L, WATKINS PB, DALY AK and AITHAL GP, 2021. Clin Pharmacol Ther. 109(4), 1125-1135
• MEHTA O, INBARAJ LR, ASTBURY S, GROVE JI, NORMAN G, AITHAL GP, VALDES AM and VIJAY A, 2021. Front Nutr.. 23(8), 595756
• AL-AWADI A, GROVE JI, TAYLOR MA, VALDES AM, VIJAY A, BAWDEN S, GOWLAND P and AITHAL GP, 2021. BMJ Open. Oct 7;11(10):e045802,
• STICKEL, FELIX, LUTZ, PHILIPP, BUCH, STEPHAN, NISCHALKE, HANS DIETER, SILVA, INES, RAUSCH, VANESSA, FISCHER, JANETT, WEISS, KARL HEINZ, GOTTHARDT, DANIEL, ROSENDAHL, JONAS, MAROT, ASTRID, ELAMLY, MONA, KRAWCZYK, MARCIN, CASPER, MARKUS, LAMMERT, FRANK, BUCKLEY, THOMAS WM, MCQUILLIN, ANDREW, SPENGLER, ULRICH, EYER, FLORIAN, VOGEL, ARNDT, MARHENKE, SILKE, VON FELDEN, JOHANN, WEGE, HENNING, SHARMA, ROHINI, ATKINSON, STEPHEN, FRANKE, ANDRE, NEHRING, SOPHIE, MOSER, VINCENT, SCHAFMAYER, CLEMENS, SPAHR, LAURENT, LACKNER, CAROLIN, STAUBER, RUDOLF E., CANBAY, ALI, LINK, ALEXANDER, VALENTI, LUCA, GROVE, JANE I., AITHAL, GURUPRASAD P., MARQUARDT, JENS U., FATEEN, WALEED, ZOPF, STEFFEN, DUFOUR, JEAN-FRANCOIS, TREBICKA, JONEL, DATZ, CHRISTIAN, DELTENRE, PIERRE, MUELLER, SEBASTIAN, BERG, THOMAS, HAMPE, JOCHEN and MORGAN, MARSHA Y, 2020. Hepatology. 72(1), 88-102
• MOOLLA, AHMAD, DE BOER, JASPER, PAVLOV, DAVID, AMIN, AMIN, TAYLOR, ANGELA, GILLIGAN, LORNA, HUGHES, BEVERLY, RYAN, JOHN, BARNES, ELEANOR, HASSAN-SMITH, ZAKI, GROVE, JANE, AITHAL, GURUPRASAD P., VERRIJKEN, AN, FRANCQUE, SVEN, VAN GAAL, LUC, ARMSTRONG, MATTHEW J., NEWSOME, PHILLIP N., COBBOLD, JEREMY F., ARLT, WIEBKE, BIEHL, MICHAEL and TOMLINSON, JEREMY W., 2020. Accurate non-invasive diagnosis and staging of non-alcoholic fatty liver disease using the urinary steroid metabolome ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 51(11), 1188-1197
• VIJAY, AMRITA, MOHAN, LEENA, TAYLOR, MOIRA A., GROVE, JANE I., VALDES, ANA M., AITHAL, GURUPRASAD P. and SHENOY, K. T., 2020. NUTRIENTS. 12(2), 383
• ATKINSON, STEPHEN R, GROVE, JANE I, LIEBIG, STEPHANIE, ASTBURY, STUART, VERGIS, NIKHIL, GOLDIN, ROBERT, QUAGLIA, ALBERTO, BANTEL, HEIKE, GUHA, INDRA NEIL, THURSZ, MARK R, NEWCOMBE, PAUL, STRNAD, PAVEL and AITHAL, GURUPRASAD P, 2020. The American Journal of Gastroenterology. 115(11), 1857-1868
• PAOLA NICOLETTI, GURUPRASAD P. AITHAL, THOMAS C. CHAMBERLAIN, THOMAS C. CHAMBERLAIN, MOHAMMAD ALSHABEEB, JANE I. GROVE, RAUL J. ANDRADE, EINAR BJORNSSON, JOHN F. DILLON, PAR HALLBERG, M. ISABEL LUCENA, ANKE H. MAITLAND-VAN DER ZEE, JENNIFER H. MARTIN, MARIAM MOLOKHIA, MUNIR PIRMOHAMED, MIA WADELIUS, YUFENG SHEN and MATTHEW R. NELSON, 2019. Clinical Pharmacology & Therapeutics. 106(1), 245-253
• STUART ASTBURY, EDMOND ATALLAH, AMRITA VIJAY, GURUPRASAD P AITHAL, JANE I GROVE and ANA M VALDES, 2019. Gut Microbes. 11(3), 569-580
• CHALMERS, JANE, BAN, LU, LEENA, KONDARAPASSERY B, EDWARDS, KIMBERLEY L, GROVE, JANE L, AITHAL, GURUPRASAD P and SHENOY, KOTACHERRY T, 2019. BMJ Open. 9(5),
• STICKEL, FELIX, LUTZ, PHILIPP, BUCH, STEPHAN, NISCHALKE, HANS DIETER, SILVA, INES, RAUSCH, VANESSA, FISCHER, JANETT, WEISS, KARL HEINZ, GOTTHARDT, DANIEL, ROSENDAHL, JONAS, MAROT, ASTRID, ELAMLY, MONA, KRAWCZYK, MARCIN, CASPER, MARKUS, LAMMERT, FRANK, BUCKLEY, THOMAS WM, MCQUILLIN, ANDREW, SPENGLER, ULRICH, EYER, FLORIAN, VOGEL, ARNDT, MARHENKE, SILKE, VON FELDEN, JOHANN, WEGE, HENNING, SHARMA, ROHINI, ATKINSON, STEPHEN, FRANKE, ANDRE, NEHRING, SOPHIE, MOSER, VINCENT, SCHAFMAYER, CLEMENS, SPAHR, LAURENT, LACKNER, CAROLIN, STAUBER, RUDOLF E, CANBAY, ALI, LINK, ALEXANDER, VALENTI, LUCA, GROVE, JANE I, AITHAL, GURUPRASAD P, MARQUARDT, JENS U, FATEEN, WALEED, ZOPF, STEFFEN, DUFOUR, JEAN-FRANCOIS, TREBICKA, JONEL, DATZ, CHRISTIAN, DELTENRE, PIERRE, MUELLER, SEBASTIAN, BERG, THOMAS, HAMPE, JOCHEN and MORGAN, MARSHA Y, 2019. Genetic variation in HSD17B13 reduces the risk of developing cirrhosis and hepatocellular carcinoma in alcohol misusers. Hepatology (Baltimore, Md.).
• GROVE JI, THIAGARAJAN P, ASTBURY S, HARRIS R, DELAHOOKE T, GUHA IN and AITHAL GP, 2018. Liver International. 38(10), 1832-1838
• KALIYAPERUMAL K, GROVE JI, DELAHAY RM, GRIFFITHS WJH, DUCKWORTH A and AITHAL GP, 2018. Journal of Hepatology. 69(4), 948-957
• DANIELS SJ, LEEMING DJ, ESLAM M, HASHEM AM, NIELSEN MJ, KRAG A, KARSDAL MA, GROVE JI, GUHA IN, KAWAGUCHI T, TORIMURA T, MCLEOD D, AKIBA J, KAYE P, DE BOER B, AITHAL GP, ADAMS LA and GEORGE J, 2018. Hepatology. 69(3), 1075-1086
• NICOLETTI P, AITHAL GP, BJORNSSON ES, ANDRADE RJ, SAWLE A, ARRESE M, BARNHART HX, BONDON-GUITTON E, HAYASHI PH, BESSONE F, CARVAJAL A, CASCORBI I, CIRULLI ET, CHALASANI N, CONFORTI A, COULTHARD SA, DALY MJ, DAY CP, DILLON JF, FONTANA RJ, GROVE JI, HALLBERG P, HERN脕NDEZ N, IB脕脩EZ L, KULLAK-UBLICK GA, LAITINEN T, LARREY D, LUCENA MI, MAITLAND-VAN DER ZEE AH, MARTIN JH, MOLOKHIA M, PIRMOHAMED M, POWELL EE, QIN S, SERRANO J, STEPHENS C, STOLZ A, WADELIUS M, WATKINS PB, FLORATOS A, SHEN Y, NELSON MR, URBAN TJ, DALY AK and , 2017. Gastroenterology. 152, 1078-1089
• ALANDIYJANY, MAHER N. AND CROXALL, NICOLA J. AND GROVE, JANE I. AND DELAHAY, ROBIN M., 2017. PLOS ONE. 12(7), 1-16
• GROVE JI, AUSTIN M, TRIBBLE J, AITHAL GP and VERMA S, 2016. Annals of Hepatology. 15(2)(Mar-Apr), 277-82
• GROVE JI and AITHAL GP, 2015. Expert opinion on drug metabolism & toxicology. 11, 395-409
• AITHAL GP and GROVE JI, 2015. Semin Liver Dis. 35(04), 421-431
• UPTON AL, GROVE JI, MAHDI AA, BRIGGS GS, MILNER DS, RUDOLPH CJ and LLOYD RG, 2014. Nucleic acids research. 42(9), 5702-5714
• GROVE, J.I., ALANDIYJANY, M.N. and DELAHAY, R.M., 2013. The Journal of Biological Chemistry. 288(37), 26385-26396
• JABERIPOUR M, VASS SO, GUISE CP, GROVE JI, KNOX RJ, HU L, HYDE EI and SEARLE PF, 2010. Biochemical pharmacology. 79(2), 102-11
• GROVE JI, WOOD SR, BRIGGS GS, OLDHAM NJ and LLOYD RG, 2009. DNA Repair. 8, 1433-1442
• GROVE JI, WOOD SR, BRIGGS GS, OLDHAM NJ and LLOYD RG, 2009. DNA repair. 8(12), 1434-43
• GROVE JI, HARRIS L, BUCKMAN C and LLOYD RG, 2008. DNA repair. 7(9), 1517-30
• RACE PR, LOVERING AL, WHITE SA, GROVE JI, SEARLE PF, WRIGHTON CW and HYDE EI, 2007. Journal of molecular biology. 368(2), 481-92
• GUISE CP, GROVE JI, HYDE EI and SEARLE PF, 2007. Gene therapy. 14(8), 690-8
• MEDDOWS, T.R., SAVORY, A.P., GROVE, J.I., MOORE, T. and LLOYD, R.G., 2005. Molecular Microbiology. 57(1), 97-110
• SEARLE PF, CHEN M, HU L, RACE PR, LOVERING AL, GROVE JI, GUISE C, JABERIPOUR M, JAMES ND, MAUTNER V, YOUNG LS, KERR DJ, MOUNTAIN A, WHITE SA and HYDE EI, 2004. Clinical and experimental pharmacology & physiology. 31(11), 811-6
• GROVE JI, LOVERING AL, GUISE C, RACE PR, WRIGHTON CJ, WHITE SA, HYDE EI and SEARLE PF, 2003. Generation of Escherichia coli nitroreductase mutants conferring improved cell sensitization to the prodrug CB1954. Cancer research. 63(17), 5532-7
• GROVE J, DALY AK, BASSENDINE MF, GILVARRY E and DAY CP, 2000. Gut. 46(4), 540-5
• GROVE JI, SEARLE PF, WEEDON SJ, GREEN NK, MCNEISH IA and KERR DJ, 1999. Virus-directed enzyme prodrug therapy using CB1954. Anti-cancer drug design. 14(6), 461-72
• EAVES DJ, GROVE J, STAUDENMANN W, JAMES P, POOLE RK, WHITE SA, GRIFFITHS I and COLE JA, 1998. Molecular microbiology. 28(1), 205-16
• GROVE J, DALY AK, BURT AD, GUZAIL M, JAMES OF, BASSENDINE MF and DAY CP, 1998. Gut. 43(2), 262-6
• FRAYLING T, ELLARD S, GROVE J, WALKER M and HATTERSLEY AT, 1998. Lancet. 351(9120), 1933-4
• GROVE J, BROWN AS, DALY AK, BASSENDINE MF, JAMES OF and DAY CP, 1998. Pharmacogenetics. 8(4), 335-42
• GROVE J, DALY AK, BASSENDINE MF and DAY CP, 1997. Hepatology (Baltimore, Md.). 26(1), 143-6
• GROVE J, TANAPONGPIPAT S, THOMAS G, GRIFFITHS L, CROOKE H and COLE J, 1996. Molecular microbiology. 19(3), 467-81
• IOBBI-NIVOL C, CROOKE H, GRIFFITHS L, GROVE J, HUSSAIN H, POMMIER J, MEJEAN V and COLE JA, 1994. FEMS microbiology letters. 119(1-2), 89-94
• DARWIN A, HUSSAIN H, GRIFFITHS L, GROVE J, SAMBONGI Y, BUSBY S and COLE J, 1993. Molecular microbiology. 9(6), 1255-65
• AITHAL GP and GROVE JI, Mechanisms of alcohol toxicity. In: NEUBERGER J, ed., Alcohol abuse and liver disease 55-64