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Eleanor Mitchell

Professor of Clinical Trials and Global Health, Faculty of Medicine & Health Sciences

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Biography

Eleanor is a Professor of Clinical Trials and Global Health and has worked in clinical research since 2002 at the 糖心原创 and in the Nottingham Clinical Trials Unit (NCTU) (/nctu/) since 2008.

Her main research interests are maternal and newborn health and she has led studies in the UK and internationally, focusing on research in low and middle income countries. She leads large collaborations designing and delivering clinical trials in a range of clinical areas and is an investigator on a number of large UK-based studies in maternal and newborn health. She is the co-Chief Investigator of the GILD trial , a multi-centre trial of women with gestational diabetes in the UK and Chief Investigator of the NEWS-HEAT trial (https://gtr.ukri.org/projects?ref=MR%2FZ505365%2F1) a large, cluster randomised clinical trial of neonatal early warning scores in Kenya, as well as being a co-investigator on many other large, multi-centre clinical trials. Information about the trials being conducted in the Nottingham Clinical Trials Unit can be found here: www.nctu.ac.uk

She is also interested in research methodology around how we conduct clinical trials to answer important clinical questions, and has led several methodology studies, including investigating training of clinical trial site staff, and the professional development of people working in research methodologist roles. She is the former Chair of the UK Trial Managers' Network (www.tmn.ac.uk) and current host organisation representative, and through this role has advocated nationally for better career pathways for people working in trial management roles. She leads outreach work with parents interested in maternal and newborn health and co-leads a national Facebook group called Bump2Baby Parents' Voices, where she talks to parents and expectant parents about research, including contributing to design and conduct of studies. Eleanor is the Teaching and Learning lead within the Nottingham Clinical Trials Unit, and Chairs the Education Committee, with responsibility for staff training leads. She is the Director of Global Engagement within the School of Medicine. Outside of the 糖心原创, she also provides her expertise on several publicly-funded clinical trials via roles on independent steering committees, and is a member of several funding boards, including the Swedish Research Council, the NIHR Academy Team Science Selection Committee and the CRUK CTU infrastructure funding.

Teaching Summary

Eleanor is NCTU Teaching and Learning lead, with responsibility for oversight of all teaching related activity in the Unit.

Research Summary

Chief Investigator

NIHR-funded GILD trial evaluating intrapartum blood glucose monitoring strategies for women/birthing people with gestational diabetes: https://fundingawards.nihr.ac.uk/award/NIHR159223

UKRI-funded NEWS-HEAT trial, evaluating a care bundle aimed at hypothermia reduction in preterm infants in Kenya.

Co-investigator

The FEED1 Trial, evaluating feeding in preterm infants: www.feed1.ac.uk

The GBS3 Trial, evaluating routine testing for Group B Streptococcus in pregnancy: www.gbs3trial.ac.uk

The ACNE-ID Trial, evaluating different doses of isotretinoin for the treatment of acne: https://www.acne-id.ac.uk/

The OTTER Trial, evaluating omeprazole for the treatment if gastro-oesophageal reflux in babies born preterm and at term - details to be added soon

The RAPID trial, a programme of online trials designed with citizen scientists: https://rapideczematrials.org/

The AZIN-V trial, a cluster trial comparing azithromycin for the prevention of maternal sepsis in Nigeria, in collaboration with the University of Lagos, Nigeria: https://azinvtrial.com/

Other funded trials will be added once contracts are in place

Recent Publications

  • MITCHELL, ELEANOR J., BENJAMIN, SANTOSH, ONONGE, SAM, DITAI, JAMES, QURESHI, ZAHIDA, MASOOD, SHABEEN NAZ, WHITHAM, DIANE, GODOLPHIN, PETER J. and DULEY, LELIA, 2020. Identifying women giving birth preterm and care at the time of birth: a prospective audit of births at six hospitals in India, Kenya, Pakistan and Uganda BMC PREGNANCY AND CHILDBIRTH. 20(1),
  • CHALMERS, JOANNE R., HAINES, RACHEL H., BRADSHAW, LUCY E., MONTGOMERY, ALAN A., THOMAS, KIM S., BROWN, SARA J., RIDD, MATTHEW J., LAWTON, SANDRA, SIMPSON, ERIC L., CORK, MICHAEL J., SACH, TRACEY H., FLOHR, CARSTEN, MITCHELL, ELEANOR J., SWINDEN, RICHARD, TARR, STELLA, DAVIES-JONES, SUSAN, JAY, NICOLA, KELLEHER, MAEVE M., PERKIN, MICHAEL R., BOYLE, ROBERT J. and WILLIAMS, HYWEL C., 2020. Daily emollient during infancy for prevention of eczema: the BEEP randomised controlled trial LANCET. 395(10228), 962-972
  • BRADSHAW L, SAWYER A, ARMSTRONG-BUISSERET L, MITCHELL E, AYERS S and DULEY L, 2019. BMC pregnancy and childbirth. 19(1), 78
  • BRADSHAW L, SAWYER A, MITCHELL E, ARMSTRONG-BUISSERET L, AYERS S and DULEY L, 2019. Trials. 20(1), 225
  • MITCHELL, ELEANOR J., BENJAMIN, SANTOSH, ONONGE, SAM, DITAI, JAMES, QURESHI, ZAHIDA, MASOOD, SHABEEN NAZ, WHITHAM, DIANE, GODOLPHIN, PETER J. and DULEY, LELIA, 2020. Identifying women giving birth preterm and care at the time of birth: a prospective audit of births at six hospitals in India, Kenya, Pakistan and Uganda BMC PREGNANCY AND CHILDBIRTH. 20(1),
  • CHALMERS, JOANNE R., HAINES, RACHEL H., BRADSHAW, LUCY E., MONTGOMERY, ALAN A., THOMAS, KIM S., BROWN, SARA J., RIDD, MATTHEW J., LAWTON, SANDRA, SIMPSON, ERIC L., CORK, MICHAEL J., SACH, TRACEY H., FLOHR, CARSTEN, MITCHELL, ELEANOR J., SWINDEN, RICHARD, TARR, STELLA, DAVIES-JONES, SUSAN, JAY, NICOLA, KELLEHER, MAEVE M., PERKIN, MICHAEL R., BOYLE, ROBERT J. and WILLIAMS, HYWEL C., 2020. Daily emollient during infancy for prevention of eczema: the BEEP randomised controlled trial LANCET. 395(10228), 962-972
  • BRADSHAW L, SAWYER A, ARMSTRONG-BUISSERET L, MITCHELL E, AYERS S and DULEY L, 2019. BMC pregnancy and childbirth. 19(1), 78
  • BRADSHAW L, SAWYER A, MITCHELL E, ARMSTRONG-BUISSERET L, AYERS S and DULEY L, 2019. Trials. 20(1), 225
  • OJHA S, MITCHELL E, MONTGOMERY A and DORLING J, 2019. Neonatology. 116(1), 67
  • WAKE, E. V., BATCHELOR, J., LAWTON, S., THOMAS, K. S., HARRISON, E. F. and COWDELL, F. C., 2018. BRITISH JOURNAL OF DERMATOLOGY. 178(1), 183-190
  • MCKEEVER T, MORTIMER K, WILSON A, WALKER S, BRIGHTLING C, SKEGGS A, PAVORD I, PRICE D, DULEY L, THOMAS M, BRADSHAW L, HIGGINS B, HAYDOCK R, MITCHELL E, DEVEREUX G and HARRISON T, 2018. The New England journal of medicine. 378(10), 902-910
  • HAINES RH, THOMAS KS, MONTGOMERY AA, RAVENSCROFT JC, AKRAM P, CHALMERS JR, WHITHAM D, DULEY L, ELEFTHERIADOU V, MEAKIN G, MITCHELL EJ, WHITE J, ROGERS A, SACH T, SANTER M, TAN W, HEPBURN T, WILLIAMS HC and BATCHELOR J, 2018. BMJ open. 8(4), e018649
  • ARMSTRONG-BUISSERET, LINDSAY, MITCHELL, ELEANOR, HEPBURN, TRISH, DULEY, LELIA, THORNTON, JIM G., ROBERTS, TRACY E., STOREY, CLAIRE, SMYTH, REBECCA and HEAZELL, ALEXANDER E. P., 2018. TRIALS. 19,
  • PATSKO E, GODOLPHIN PJ, THOMAS KS, HEPBURN T, MITCHELL EJ, CRAIG FE, BATH PM and MONTGOMERY AA, 2017. Trials. 18(1), 53
  • THOMAS KS, BRADSHAW LE, SACH TH, COWDELL F, BATCHELOR JM, LAWTON S, HARRISON EF, HAINES RH, AHMED A, DEAN T, BURROWS NP, POLLOCK I, BUCKLEY HK, WILLIAMS HC, LLEWELLYN J, CRANG C, GRUNDY JD, GUINESS J, GRIBBIN A, WAKE EV, MITCHELL EJ, BROWN SJ and MONTGOMERY AA, 2017. Health technology assessment (Winchester, England). 21(16), 1-260
  • THOMAS KS, BRADSHAW LE, SACH TH, BATCHELOR JM, LAWTON S, HARRISON EF, HAINES RH, AHMED A, WILLIAMS HC, DEAN T, BURROWS NP, POLLOCK I, LLEWELLYN J, CRANG C, GRUNDY JD, GUINESS J, GRIBBIN A, MITCHELL EJ, COWDELL F, BROWN SJ, MONTGOMERY AA and , 2017. PLoS medicine. 14(4), e1002280
  • CHALMERS JR, HAINES RH, MITCHELL EJ, THOMAS KS, BROWN SJ, RIDD M, LAWTON S, SIMPSON EL, CORK MJ, SACH TH, BRADSHAW LE, MONTGOMERY AA, BOYLE RJ and WILLIAMS HC, 2017. Trials. 18(1), 343
  • DULEY L, DORLING J, PUSHPA-RAJAH A, ODDIE SJ, YOXALL CW, SCHOONAKKER B, BRADSHAW L, MITCHELL EJ, FAWKE J ON BEHALF OF THE CORD PILOT TRIAL COLLABORATIVE GROUP, 2017. Randomised trial of cord clamping and initial stabilisation at very preterm birth: Archives of Diseases in Childhood, Fetal and Neonatal edition Archives of Diseases in Childhood, Fetal and Neonatal edition.
  • MASON, J M, THOMAS, K S, ORMEROD, A D, CRAIG, F E, MITCHELL, E, NORRIE, J and WILLIAMS, H C, 2017. The British journal of dermatology.
  • BRADSHAW, LUCY, HEPBURN, TRISH, MONTGOMERY, ALAN A., HARRISON, ELEANOR F., MITCHELL, ELEANOR J., HOWELLS, LAURA and THOMAS, KIM S., 2017. Frequency of data collection in a randomised controlled trial for long term eczema management in children TRIALS. 18,
  • HAYDOCK, REBECCA, HARRISON, TIM, BRADSHAW, LUCY, DULEY, LELIA, SKEGGS, ANDREW and MITCHELL, ELEANOR, 2017. Evolution of a recruitment strategy between secondary and primary care during the recruitment phase of the fourfold asthma (FAST) trial TRIALS. 18,
  • HEPBURN, TRISH, BRADSHAW, LUCY E., MONTGOMERY, ALAN A., HARRISON, ELEANOR F., MITCHELL, ELEANOR J. and THOMAS, KIM S., 2017. Waiting list control designs in trials of non-pharmacological interventions for eczema TRIALS. 18,
  • BRADSHAW, LUCY, DORLING, JON, DULEY, LELIA, ARMSTRONG-BUISSERET, LINDSAY, FAWKE, JOE, SCHOONAKKER, BERNARD, MITCHELL, ELEANOR and DINEEN, ROB, 2017. Intra and inter-observer agreement in the interpretation of preterm neonatal cranial ultrasound scans TRIALS. 18,
  • WILKES SR, WILLIAMS HC, ORMEROD AD, CRAIG FE, GREENLAW N, NORRIE J, MITCHELL EJ, MASON JM, THOMAS KS and , 2016. Journal of the American Academy of Dermatology. 75(6), 1216-1220
  • THOMAS KS, ORMEROD AD, CRAIG FE, GREENLAW N, NORRIE J, MITCHELL E, MASON JM, JOHNSTON GA, WAHIE S, WILLIAMS HC and , 2016. Journal of the American Academy of Dermatology. 75(5), 940-949
  • SKEGGS A, MCKEEVER T, DULEY L, MITCHELL E, BRADSHAW L, MORTIMER K, WALKER S, PARROTT S, WILSON A, PAVORD I, BRIGHTLING C, THOMAS M, PRICE D, DEVEREUX G, HIGGINS B, HARRISON T and HAYDOCK R, 2016. Trials. 17(1), 499
  • THOMAS, K. S., BATCHELOR, J. M., BATH-HEXTALL, F., CHALMERS, J. R., CLARKE, T., CROWE, S., DELAMERE, F. M., ELEFTHERIADOU, V., EVANS, N., FIRKINS, L., GREENLAW, N., LANSBURY, L., LAWTON, S., LAYFIELD, C., LEONARDI-BEE, J., MASON, J., MITCHELL, E., NANKERVIS, H., NORRIE, J., NUNN, A., ORMEROD, A. D., PATEL, R., PERKINS, W., RAVENSCROFT, J. C., SCHMITT, J., SIMPSON, E., WHITTON, M. E. and WILLIAMS, H. C., 2016. Programme Grants Appl Res. 4(18),
  • HARRISON EF, HAINES RH, COWDELL F, SACH TH, DEAN T, POLLOCK I, BURROWS NP, BUCKLEY H, BATCHELOR J, WILLIAMS HC, LAWTON S, BROWN SJ, BRADSHAW LE, AHMED A, MONTGOMERY AA, MITCHELL EJ and THOMAS KS, 2015. Trials. 16(1), 390
  • ORMEROD AD, THOMAS KS, CRAIG FE, MITCHELL E, GREENLAW N, NORRIE J, MASON JM, WALTON S, JOHNSTON GA, WILLIAMS HC and UK DERMATOLOGY CLINICAL TRIALS NETWORK鈥橲 STOP GAP TEAM, 2015. Comparison of the two most commonly used treatments for pyoderma gangrenosum: results of the STOP GAP randomised controlled trial. BMJ (Clinical research ed.). 350, h2958
  • BRADSHAW, LUCY E., PUSHPA-RAJAH, ANGELA, DORLING, JON, MITCHELL, ELEANOR J. and DULEY, LELIA, 2015. TRIALS. 16,
  • LELIA DULEY, ANGELA PUSHPA-RAJAH, LUCY BRADSHAW, JON DORLING, ELEANOR MITCHELL, 2015. Trials.
  • SPRANGE, KIRSTY, MITCHELL, ELEANOR, HULL, MARK and BUMPHREY, GILL, 2015. TRIALS. 16,
  • 2014. Trials. 15:258,
  • MITCHELL E ET AL, 2013. Trials.
  • CRAIG, F.F., THOMAS, K.S., MITCHELL, E.J., WILLIAMS, H.C., NORRIE, J., MASON, J.M. and ORMEROD, A.D., 2012. Trials. 13(April), 51
  • MITCHELL, E., 2010. Wounds UK. 6(4), 27-32
  • MITCHELL, E., 2010. Do you see patients with pyoderma gangrenosum? If so, consider referral to STOP GAP trial Leg Ulcer Forum Journal. 2010(24), 46-48 (In Press.)

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糖心原创
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