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David Humes

Professor of Colorectal Surgery, Faculty of Medicine & Health Sciences

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Biography

Prof Humes heads a research group focusing on the use of routinely collected data to study the occurrence and consequences of surgical diseases alongside delivering studies on the use of novel interventional and diagnostic devices. He has supervised 7 PhD's to completion and his current research group includes 6 PhD students, 2 NIHR Academic Clinical Fellows, a Clinical Lecturer and a data analyst. He has been awarded over 拢4.1 million in grant funding and published 115 peer-reviewed articles with a current H-index of 44 (Google Scholar) with over 7500 citations. He has implemented and evaluated the symptomatic FIT pathway in Nottingham and is leading NIHR and CRUK funded studies in this research area currently using local, National (CPRD and SAIL) and International (Danish) data. He was the research lead for the Joint Committee on Higher Surgical Training. He is current Academic Career Development lead in the NIHR BRC in Nottingham and Deputy Director of the Nottingham Integrated Academic Training pathway. His clinical practice focuses on robotic colorectal and anal cancer surgery.

Research Summary

Prof Humes is currently supervising studies on the role of Faecal Immunochemical testing in the diagnosis of colorectal cancer. He is leading an NIHR RfPB funded study detailing the use of FIT in… read more

Selected Publications

  • CHOWDHURY, A. H., HUMES, D. J., PRITCHARD, S. E., MARCIANI, L., GOWLAND, P. A., SIMPSON, J. and LOBO, D. N., 2011. World Journal of Surgery. 35(9), 2102-2109
  • SMITH, J K, MARCIANI, L, HUMES, D J, FRANCIS, S T, GOWLAND, P and SPILLER, R C, 2016. Anticipation of thermal pain in diverticular disease. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 28(6), 900-13
  • ABDUL SULTAN A, WEST J, BAN L, HUMES D, TATA LJ, FLEMING KM, NELSON-PIERCY C and CARD T, 2016. Inflammatory bowel diseases. 22(7), 1621-30
  • HUMES DJ, AHMED I and LOBO DN, 2010. Archives Of Surgery (Chicago, Ill. : 1960). 145(1), 96-8

Current Research

Prof Humes is currently supervising studies on the role of Faecal Immunochemical testing in the diagnosis of colorectal cancer. He is leading an NIHR RfPB funded study detailing the use of FIT in follow up of colorectal cancer. He is supervising two NIHR Doctoral fellows undertaking studies on the use of FIT and its implementation in the UK. His is undertaking a TET CRUK funded project on the use of risk stratification in the diagnosis of colorectal cancer using FIT and other parameters.

Past Research

I completed my PhD on symptom aetiology in diverticular disease and the epidemiology of perforated diverticular disease. Since completion of my PhD my post doctoral work has focused on the epidemiology of complicated diverticular disease, venous thromboembolism following surgery, appendicitis and inflammatory bowel disease. I have supervised 3 PhD students on studies relating to surgical training in the UK.

  • MCGRANE JM, HUMES DJ, ACHESON AG, MINEAR F, WHEELER JMD and WALTER CJ, 2017. Clinical colorectal cancer. (In Press.)
  • BANERJEA A, VOLL J, CHOWDHURY A, SIDDIKA A, THOMSON S, BRIGGS R, HUMES DJ and , 2017. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. (In Press.)
  • DAVID J HUMES, ALEX J WALKER, BEVERLEY HUNT, ALYSHAH ABDUL SULTAN, JONAS LUDVIGSSON and JOE WEST, 2016. British Journal of Surgery. 103(4), 443-450
  • SMITH, J K, MARCIANI, L, HUMES, D J, FRANCIS, S T, GOWLAND, P and SPILLER, R C, 2016. Anticipation of thermal pain in diverticular disease. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 28(6), 900-13
  • ABDUL SULTAN A, WEST J, BAN L, HUMES D, TATA LJ, FLEMING KM, NELSON-PIERCY C and CARD T, 2016. Inflammatory bowel diseases. 22(7), 1621-30
  • 2016. World journal of surgery. (In Press.)
  • HUMES D and SPILLER RC, 2016. Colonic diverticular disease: medical treatments for acute diverticulitis. BMJ clinical evidence. 2016,
  • SMITH JK, MARCIANI L, HUMES DJ, FRANCIS ST, GOWLAND P and SPILLER RC, 2016. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 28(6), 900-13
  • HUMES DJ, LUDVIGSSON JF and JARVHOLM B, 2016. Diseases of the colon and rectum. 59(2), 110-4
  • HUMES DJ, WALKER AJ, HUNT BJ, SULTAN AA, LUDVIGSSON JF and WEST J, 2016. The British journal of surgery. 103(4), 443-50
  • ELSEY EJ, GRIFFITHS G, HUMES DJ and WEST J, 2016. The British journal of surgery. 104(1), 22-33
  • S脴REIDE K, BOERMEESTER MA, HUMES DJ and VELMAHOS GC, 2016. Scandinavian journal of gastroenterology. 51(12), 1416-1422
  • HUMES DJ, NORDENSKJ脰LD A, WALKER AJ, WEST J and LUDVIGSSON JF, 2015. Journal of pediatric surgery. (In Press.)
  • SULTAN, A.A., WEST, J., STEPHANSSON, O., GRAINGE, M.J., TATA, L.J., FLEMING, K.M., HUMES, D., LUDVIGSSON, J.F., 2015. BMJ Open. 5(11),
  • GEMMILL EH, HUMES DJ and CATTON JA, 2015. Annals of the Royal College of Surgeons of England. 97(3), 173-9
  • ABDUL SULTAN A, WEST J, STEPHANSSON O, GRAINGE MJ, TATA LJ, FLEMING KM, HUMES D and LUDVIGSSON JF, 2015. BMJ open. 5(11), e008864
  • HUMES DJ, WALKER AJ, BLACKWELL J, HUNT BJ and WEST J, 2015. The British journal of surgery. 102(13), 1629-38
  • BAN L, TATA LJ, HUMES DJ, FIASCHI L and CARD T, 2015. Alimentary pharmacology & therapeutics. 42(7), 855-66
  • HUMES, D. J. and SPILLER, R. C., 2014. ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 39(4), 359-370
  • ZINGONE F, SULTAN AA, HUMES DJ and WEST J, 2014. Annals of surgery. 261(2), 332-337
  • WALKER AJ, WEST J, CARD TR, HUMES DJ and GRAINGE MJ, 2014. Journal of thrombosis and haemostasis : JTH. 12(5), 641-9
  • TANG, J., HUMES, D. J., GEMMIL, E., WELCH, N. T., PARSONS, S. L. and CATTON, J. A., 2013. ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND. 95(5), 323-328
  • HUMES, D. J., RADCLIFFE, R. S., CAMM, C. and WEST, J., 2013. BRITISH JOURNAL OF SURGERY. 100(13), 1827-1832
  • AL-KHYATT W, THOMAS JD, HUMES DJ and LOBO DN, 2013. Journal of medical case reports. 7, 25
  • HUMES, D.J., SIMPSON, J., SMITH, J., SUTTON, P., ZAITOUN, A., BUSH, D., BENNETT, A., SCHOLEFIELD, J.H. and SPILLER, R.C., 2012. Neurogastroenterology & Motility. 24(4), e163
  • HUMES DJ, 2012. Diagnosing and managing acute diverticulitis. The Practitioner. 256(1753), 21-3, 2-3
  • HUMES DJ, 2012. Digestive diseases (Basel, Switzerland). 30(1), 6-11
  • HUMES, D.J., FLEMING, K.M., SPILLER, R.C. and WEST, J., 2011. Gut. 60(2), 219-224
  • HUMES, DAVID J and WEST, JOE, 2011. BMJ (Clinical research ed.). 343, d4115
  • HUMES, D.J. and WEST, J., 2011. Gut. 61(1), 95-100
  • SMITH, J. K., HUMES, D. J., HEAD, K. E., BUSH, D., WHITE, T. P., STEVENSON, C. M., BROOKES, M. J., MARCIANI, L., SPILLER, R .C., GOWLAND, P. A. and FRANCIS, S. T., 2011. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
  • CHOWDHURY, A. H., HUMES, D. J., PRITCHARD, S. E., MARCIANI, L., GOWLAND, P. A., SIMPSON, J. and LOBO, D. N., 2011. World Journal of Surgery. 35(9), 2102-2109
  • SMITH J, HUMES DJ and SPILLER RC, 2011. Should We Treat Uncomplicated Symptomatic Diverticular Disease With Fibre? Bmj (Clinical Research Ed.). 342, d2951
  • HUMES D, SMITH JK and SPILLER RC, 2011. Colonic Diverticular Disease. American Family Physician. 84(10), 1163-4
  • HUMES D, SMITH JK and SPILLER RC, 2011. Colonic Diverticular Disease. Clinical Evidence. 2011,
  • SPILLER RC, HUMES DJ, CAMPBELL E, HASTINGS M, NEAL KR, DUKES GE and WHORWELL PJ, 2010. Alimentary Pharmacology & Therapeutics. 32(6), 811-20
  • HUMES DJ, AHMED I and LOBO DN, 2010. Archives Of Surgery (Chicago, Ill. : 1960). 145(1), 96-8
  • VARADHAN KK, HUMES DJ, NEAL KR and LOBO DN, 2010. World Journal Of Surgery. 34(2), 199-209
  • HUMES, D.J., SOLAYMANI-DODARAN, M., FLEMING, K.M., SIMPSON, J., SPILLER, R.C. and WEST, J., 2009. Gastroenterology. 136(4), 1198-1205
  • SIMPSON J, SUNDER F, HUMES DJ, JENKINS D, SCHOLEFIELD JH, SPILLER RC, 2009. Neurogastroenterol Motility. 21(8), 847-858
  • MACAFEE DAL, HUMES DJ, BOULIOTIS G, BECKINGHAM IJ, WHYNES DK and LOBO DN, 2009. The British journal of surgery. 96(9), 1031-40
  • SUTTON PA, HUMES DJ, PURCELL G, SMITH JK, WHITING F, WRIGHT T, MORGAN L and LOBO DN, 2009. Annals of the Royal College of Surgeons of England. 91(5), 381-4
  • SIMPSON J, SUNDER F, HUMES DJ, JENKINS D, WAKELIN D, SCHOLEFIELD JH, SPILLER RC, 2008. Neurogastroenterol Motility. 20(4), 392-406
  • HUMES, D.J., SIMPSON, J., NEAL, K.R., SCHOLEFIELD, J.H. and SPILLER, R.C., 2008. British Journal of Surgery. 95(2), 195-198
  • SIMPSON J, HUMES DJ, O'ROURKE EJ, JAMES PD and ACHESON AG, 2008. Gut. 57(6), 798, 836
  • HUMES D, SIMPSON J and SPILLER RC, 2007. Colonic Diverticular Disease. Clinical Evidence. 2007,
  • HUMES D, SPEAKE WJ and SIMPSON J, 2007. Appendicitis. Clinical Evidence. 2007,
  • HUMES, D.J. and SIMPSON, J., 2006. BMJ. 333(7567), 530-534
  • HUMES, DAVID and LOBO, DILEEP N, 2005. Gastrointestinal Endoscopy. 62(4), 610
  • HUMES D, J脛HNICH H, REHM A and COMPSON JP, 2004. The Osteology Of The Trapezium. Journal Of Hand Surgery (Edinburgh, Scotland). 29(1), 42-5

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