糖心原创

Contact

• workDepartment of Histopathology
  Queen's Medical Centre
  Nottingham
  NG7 2UH
  UK
• work01159249924
• Abhik.Mukherjee1@nottingham.ac.uk

Biography

Dr Mukherjee studied Medicine and trained in Radiation Oncology at Calcutta University; and thereafter completed an MSc and PhD in Oncology from the 糖心原创. He subsequently trained in Histopathology at Leicester and Nottingham, where he was an NIHR Academic Clinical Fellow and Lecturer. After attaining his FRCPath (Histopathology) by exam in 2015, he is currently a Clinical Associate Professor (Honorary Consultant) at Nottingham University and Nottingham University Hospitals NHS Trust.

His research interests are molecular characterisation of lympho-vascular invasion in cancers, low grade breast cancer biology and biomarkers in inflammatory bowel disease. He has held project grants from Cancer Research UK, Academy of Medical Sciences and the Pathological Society and has had the privilege of working on prestigious collaborative projects [METABRIC: Molecular Taxonomy of the Breast Cancer International Consortium], clinical trials [NEOTANGO, SCOTROC/TRANSCOTROC] and industry led computational pathology initiatives [Optimata, Israel and Barco, Belgium].

He is currently co-leading the development of the MSc in Molecular Pathology for the Nottingham Molecular Pathology Node (Work Stream 9) and also sits on the NCRI-CMPath Clinical Trials Pathology Advisory Group (CT-PAG) and educational subcommittee of the Pathological Society of Great Britain and Ireland.

He holds several peer-reviewed publications and has presented his research at National and International Conferences with several bursaries/awards from the British Association of Cancer Research, British MicroCirculation Society and the Cancer Research UK.

Expertise Summary

Dr Mukherjee's current interests are in colorectal and breast cancer pathology and biomarkers/molecular signatures of metastases and response to therapy. He has extensive experience of breast, ovarian and colorectal cancer research. This includes molecular/immunological markers of prognosis and prediction of response to therapeutic agents. He has also a strong background in researching the mechanism of action of novel drugs (including anti-angiogenic agents) and validation of drug targets used in cancer therapy. He is also interested in inflammatory bowel diseases especially novel molecular techniques aiding pathological diagnosis.

Selected Publications

• MUKHERJEE A and RAKHA E, 2012. Integrating breast cancer genetics into clinical practice. Women's Health (Lond Engl). 8(1), 99-112
• MUKHERJEE, A., SHEHATA, M., MOSELEY, P., RAKHA, E., ELLIS, I. and CHAN, S., 2010. British Journal of Cancer. 103(12), 1794-1800
• SHEHATA, M., MUKHERJEE, A., DEEN, S., AL-ATTAR, A., DURRANT, L.G. and CHAN, S., 2009. British Journal of Cancer. 101, 1321-1328
• MUKHERJEE A, MARTIN SG., 2008. The thioredoxin system: a key target in tumour and endothelial cells. British Journal of Radiology. Spec No 1, S57-68

• View all publications

• QAISER T, MUKHERJEE A, REDDY PB C, MUNUGOTI SD, TALLAM V, PITK脛AHO T, LEHTIM脛KI T, NAUGHTON T, BERSETH M, PEDRAZA A, MUKUNDAN R, SMITH M, BHALERAO A, RODNER E, SIMON M, DENZLER J, HUANG CH, BUENO G, SNEAD D, ELLIS IO, ILYAS M and RAJPOOT N, 2018. Histopathology. 72(2), 227-238
• ALESKANDARANY MA, SONBUL S, SURRIDGE R, MUKHERJEE A, CALDAS C, DIEZ-RODRIGUEZ M, ASHANKYTY I, ALBRAHIM KI, ELMOUNA AM, ANEJA R, MARTIN SG, ELLIS IO, GREEN AR and RAKHA EA, 2018. British journal of cancer. 117(8), 1176-1184
• CHRYSANTHOU E, GORRINGE KL, JOSEPH C, CRAZE M, NOLAN CC, DIEZ-RODRIGUEZ M, GREEN AR, RAKHA EA, ELLIS IO and MUKHERJEE A, 2017. Breast cancer research and treatment.
• SONBUL SN, GORRINGE KL, ALESKANDARANY MA, MUKHERJEE A, GREEN AR, ELLIS IO and RAKHA EA, 2017. The journal of pathology. Clinical research. 3(2), 105-114
• MILIGY I, MOHAN P, GABER A, ALESKANDARANY MA, NOLAN CC, DIEZ-RODRIGUEZ M, MUKHERJEE A, CHAPMAN C, ELLIS IO, GREEN AR and RAKHA EA, 2017. Histopathology. 71(2), :258-268
• PEREIRA B, CHIN SF, RUEDA OM, VOLLAN HK, PROVENZANO E, BARDWELL HA, PUGH M, JONES L, RUSSELL R, SAMMUT SJ, TSUI DW, LIU B, DAWSON SJ, ABRAHAM J, NORTHEN H, PEDEN JF, MUKHERJEE A, TURASHVILI G, GREEN AR, MCKINNEY S, OLOUMI A, SHAH S, ROSENFELD N, MURPHY L, BENTLEY DR, ELLIS IO, PURUSHOTHAM A, PINDER SE, B脴RRESEN-DALE AL, EARL HM, PHAROAH PD, ROSS MT, APARICIO S and CALDAS C, 2016. Nature communications. 7, 11479
• JOSEPH, C., RUSSELL, R., CRAZE, M., NOLAN, C., PROVENZANO, E., CALDAS, C., GREEN, A., RAKHA, E., ELLIS, I. O. and MUKHERJEE, A., 2016. The Prognostic Significance of KRAS-Induced Actin-Interacting Protein (KRAP) Expression in Invasive Breast Cancer JOURNAL OF PATHOLOGY. 240, 16-16
• SONBUL, S. N., PIGERA, M., MUKHERJEE, A., ALESKANDARANY, M. A., GREEN, A. R., DIEZ-RODRIGUEZ, M., JOSEPH, C., NOLAN, C. C., ELLIS, I. O. and RAKHA, E. A., 2016. Ankyrin 3 Protein may Influence DNA-Damage Response Pathways and the Immune Response in Invasive Breast Carcinoma JOURNAL OF PATHOLOGY. 240, 19-19
• SONBUL, S. N., MUKHERJEE, A., RUSSELL, R., RUEDA, O. M., ALESKANDARANY, M. A., GREEN, A. R., NOLAN, C. C., DIEZ-RODRIGUEZ, M., PROVENZANO, E., CALDAS, C., ELLIS, I. O. and RAKHA, E. A., 2016. Multiple Coagulation Factor Deficiency Protein-2 (MCFD2) as a Potential Prognostic Germ Cell Marker in Invasive Breast Carcinoma: a Transcriptome-Driven 糖心原创 JOURNAL OF PATHOLOGY. 240, 21-21
• MILIGY, I., GABER, A., MOHAN, P., NOLAN, C., DIEZ-RODRIGUEZ, M., CRAZE, M., JOSEPH, C., AL-KAABI, M. M., ALESKANDARANY, M. A., MUKHERJEE, A., CHAPMAN, C., MACMILLAN, R. D., ELLIS, I. O., GREEN, A. R. and RAKHA, E. A., 2016. Prognostic Significance of Tumour Infiltrating Lymphocytes in Ductal Carcinoma In Situ JOURNAL OF PATHOLOGY. 240, 26-26
• BARUS, N., JOSEPH, C., CRAZE, M., ALIYEVA, T., OJIEGBE, S., NOLAN, C., DIEZ-RODRIGUEZ, M., GREEN, A. R., RAKHA, E., ELLIS, I. O. and MUKHERJEE, A., 2016. Loss of Latent MMP7 Leads to Increased Lympho-Vascular Invasion and Poor Prognosis in Breast Cancer JOURNAL OF PATHOLOGY. 240, 26-26
• CRAZE, M., JOSEPH, C., RUSSELL, R., RUEDA, O. M., PROVENZANO, E., CALDAS, C., GREEN, A. R., RAKHA, E., ELLIS, I. O. and MUKHERJEE, A., 2016. Phosphorylation Status of MED1 Protein Results in Differential Prognosis in Breast Cancer JOURNAL OF PATHOLOGY. 240, 26-26
• BARUS, N., JOSEPH, C., CRAZE, M., PROVENZANO, E., RUSSELL, R., CALDAS, C., GREEN, A. R., RAKHA, E., ELLIS, I. O. and MUKHERJEE, A., 2016. Investigating the Role of CREM Protein in Lymphovascular Invasion in Breast Cancer JOURNAL OF PATHOLOGY. 240, 26-26
• SONBUL, S. N., MUKHERJEE, A., ALESKANDARANY, M. A., RUSSELL, R., RUEDA, O., GREEN, A. R., NOLAN, C. C., DIEZ-RODRIGUEZ, M., PROVENZANO, E., CALDAS, C., ELLIS, I. O. and RAKHA, E. A., 2016. Vesicular Transporter Proteins in Invasive Breast Cancer: Clinicopathological Relevance of Synaptosomal-Associated Protein-23 (SNAP23) JOURNAL OF PATHOLOGY. 240, 15-15
• HAMARSHEH, S., CRAZE, M., JOSEPH, C., PROVENZANO, E., RUSSELL, R., CALDAS, C., GREEN, A. R., RAKHA, E., ELLIS, I. O. and MUKHERJEE, A., 2016. Nostrin as a Marker Related to Low Grade and Better Prognosis in Breast Cancer JOURNAL OF PATHOLOGY. 240, 20-20
• SONBUL, S. N., ALESKANDARANY, M. A., MUKHERJEE, A., GREEN, A. R., MILIGY, I., DIEZ-RODRIGUEZ, M., NOLAN, C. C., ELLIS, I. O. and RAKHA, E. A., 2016. Clinicopathological Impact of C-C Chemokine Receptor Type 7 (CCR7) Protein Expression in Triple Negative Breast Carcinoma (TNBC) JOURNAL OF PATHOLOGY. 240, 27-27
• JOSEPH, C., CRAZE, M., NOLAN, C., DIEZ-RODRIGUEZ, M., GREEN, A. R., RAKHA, E., ELLIS, I. O. and MUKHERJEE, A., 2016. Subcellular Localisation Specific HOXB13:IL17BR Protein Index Predicts For Poorer Prognosis and Metastatic Progression in Breast Cancer JOURNAL OF PATHOLOGY. 240, 25-25
• MARCHESSOUX, C., KAYE, P. V., MUKHERJEE, A., PAINE, S., HAIDER, A. and ILYAS, M., 2016. Digital Microscopy is Non-inferior to Optical Microscopy in the Diagnosis of Dysplasia in Barrett's Oesophagus: A Validation 糖心原创 JOURNAL OF PATHOLOGY. 240, 19-19
• CHRYSANTHOU, E., JOSEPH, C., CRAZE, M., SORIA, D., ELLIS, I. O. and MUKHERJEE, A., 2015. Phenotyping Characterisation of Breast Cancers: the Role of CDC Proteins (2, 42 & 42BPB) JOURNAL OF PATHOLOGY. 237, S31-S31
• SONBUL, S. N., MUKHERJEE, A., RUSSELL, R., RUEDA, O. M., ALESKANDARANY, M., GREEN, A. R., PROVENZANO, E., CALDAS, C., ELLIS, I. O. and RAKHA, E. A., 2015. Exploring Molecular Mechanisms Underlying Lymphovascular Invasion in Breast Cancer JOURNAL OF PATHOLOGY. 237, S19-S19
• JOSEPH, C., CRAZE, M., SORIA, D., ELLIS, I. O. and MUKHERJEE, A., 2015. Role of Mitotic Checkpoint Proteins (BUB Family) in Breast Cancer JOURNAL OF PATHOLOGY. 237, S31-S31
• CRAZE, M., JOSEPH, C., RUSSEL, R., RUEDA, O. M., PROVENZANO, E., CALDAS, C., ELLIS, I. O. and MUKHERJEE, A., 2015. SOCS2 as a Marker Related to Low Grade and Tumour Morphology in Breast Cancer JOURNAL OF PATHOLOGY. 237, S13-S13
• CRAZE, M., JOSEPH, C., NOLAN, C., GREEN, A., RAKHA, E. A., ELLIS, I. O. and MUKHERJEE, A., 2015. Molecular Pathways Involved in Lymphovascular Invasion: A Biomarker Driven Approach JOURNAL OF PATHOLOGY. 237, S17-S17
• MACNAMARA, O., JOSEPH, C., CRAZE, M., RAKHA, E. A., RUSSELL, R., RUEDA, O. M., PROVENZANO, E., CALDAS, C., ELLIS, I. O. and MUKHERJEE, A., 2015. MED7 in Breast Cancer: Relationship to Grade and Lymphovascular Invasion JOURNAL OF PATHOLOGY. 237, S31-S31
• MUKHERJEE A, JOSEPH C, CRAZE M, CHRYSANTHOU E and ELLIS IO, 2015. Lancet (London, England). 385 Suppl 1, S72
• ALESKANDARANY MA, SONBUL SN, MUKHERJEE A and RAKHA EA, 2015. Pathobiology : journal of immunopathology, molecular and cellular biology. 82(3-4), 113-23
• MUKHERJEE A and RAKHA E, 2013. Toward Personalized Breast Cancer Management: The Role of Lymphovascular Inva The Journal of Oncopathology. (In Press.)
• MUKHERJEE A and RAKHA E, 2012. Integrating breast cancer genetics into clinical practice. Women's Health (Lond Engl). 8(1), 99-112
• MUKHERJEE, A., SHEHATA, M., MOSELEY, P., RAKHA, E., ELLIS, I. and CHAN, S., 2010. British Journal of Cancer. 103(12), 1794-1800
• SHEHATA, M., MUKHERJEE, A., DEEN, S., AL-ATTAR, A., DURRANT, L.G. and CHAN, S., 2009. British Journal of Cancer. 101, 1321-1328
• MUKHERJEE A, MARTIN SG., 2008. The thioredoxin system: a key target in tumour and endothelial cells. British Journal of Radiology. Spec No 1, S57-68
• MUKHERJEE A, HUBER K, EVANS H, LAKHANI N, MARTIN S, 2007. British Journal of Pharmacology. 151, 1167-1175
• ULLENHAG G, MUKHERJEE A, WATSON NF, AL-ATTAR AH, SCHOLEFIELD JH, DURRANT LG, 2007. Clinical Cancer Research. 13(17), 5070-5075
• MARTIN SG, ORRIDGE C, MUKHERJEE A, MORGAN DA, 2007. Clin Oncol (R Coll Radiol). 19(1), 71-6
• MUKHERJEE A, DHADDA AS, SHEHATA M AND CHAN S, 2007. Expert Opinion in Pharmacotherapy. 8(13), 2189-204
• SHEHATA M, A MUKHERJEE A, SHARMA R AND CHAN S, 2007. Liposomal doxorubicin in breast cancer Women鈥檚 Health (Lond Engl). 3(5), 557-69
• MATHEW J, ASGEIRSSON KS, AGRAWAL A, MUKHERJEE A, ELLIS IO, CHEUNG KL, CHAN S, ROBERTSON JF, 2007. Neoadjuvant chemotherapy in locally advanced primary breast cancers - The Nottingham experience European Journal of Surgical Oncology. 33(8), 972-6
• MUKHERJEE A AND MARTIN S, 2006. In vitro cytotoxicity of Phortress against colorectal cancer. International Journal of Oncology. 29(5), 1287-94
• MUKHERJEE A, WESTWELL AD, BRADSHAW TD, STEVENS MF, CARMICHAEL J, MARTIN SG, 2005. British Journal of Cancer. 92(2), 350-8