糖心原创

Contact

• workRoom C209d Biodiscovery Institute
  University Park
  Nottingham
  NG7 2RD
  UK
• work0115 823 0719
• fax0115 823 0696
• beth.coyle@nottingham.ac.uk

Biography

I am an Associate Professor in the School of Medicine (tenured September 2005, promoted August 2011). I joined the 糖心原创 Children's Brain Tumour Research Centre (CBTRC) in 2002 as an independent Research Fellow, based in the School of Biology. Previously, I was a research associate (1999-2002) with Professor Gerald Cohen in the Biochemical Toxicology Section of the MRC Toxicology Unit at the University of Leicester. My first postdoctoral position (1995-1999) was with Professor Richard Trembath in the Institute of Genetics at the University of Leicester. I obtained my my PhD at the MRC Human Genetics Unit ((University of Edinburgh; supervised by Professor David Porteous) in Edinburgh in 1995 and my BSc in Molecular Biology, also from the University of Edinburgh, in 1991 .

Expertise Summary

My research has always been dominated by an interest in investigating the genetics of childhood. I started my research career carrying out linkage analysis in patient samples from two different deafness disorders (Usher's Syndrome then Pendred Syndrome), finding the gene for Pendred Syndrome (Coyle et al. 1996 Nature Genetics 12:421-3) and mapping mutations in patient samples (another 6 papers in this area). At the MRC Toxicology Unit I applied my genetics skills to understanding apoptotic pathways in leukaemic and liver cancer cells (Coyle et al. 2003 JBC 278:5920-8). Since arriving at the Children's Brain Tumour Research Centre as an independent fellow, I have focused the work of my group on developing accurate tumour models in order to circumvent drug resistance and invasion/ metastasis in ependymomas and medulloblastomas. Over the past 14 years, I have brought in ~拢2 million in funding, mainly as a Co-I, and published another 27 papers in this area, playing a key role is several large international collaborations.

Teaching Summary

I am module convenor for a BMedSci Cancer module. I lecture MSc students on the Stem Cell Technology Course and the Clinical Neuroscience Course.

In the lab I supervise BSc and BMedSci undergraduates. I also take MRes students, and MSc students on the MSc Oncology and MSc Immunology courses.

I am currently the primary supervisor for 6 PhD students (Christine Mitoko, Alice Cardall, Hannah Jackson, Louisa Taylor, James Johnson, and Philippa Wade) and second supervisor for another 5 PhD students ( Maria Eleftheriou, Johnathan Curd, Emma Barker, Susannah Entwistle and James Hudson). I am advisor to another 3 PhD students and I have several medical student and cancer biology tutees.

Research Summary

My research is mainly focused on two specific types of children's brain tumours: medulloblastoma and ependymoma both of which are inherently drug resistant. I am interested in the link between drug… read more

Recent Publications

• AHMED EM, BANDOPADHYAY G, COYLE B and GRABOWSKA A, 2018. Cellular oncology (Dordrecht). 41(3), 319-328
• 2018. Frontiers in Cell and Developmental Biology. 6, 26
• THERY, CLOTILDE, WITWER, KENNETH W., AIKAWA, ELENA, JOSE ALCARAZ, MARIA, ANDERSON, JOHNATHON D., ANDRIANTSITOHAINA, RAMAROSON, ANTONIOU, ANNA, ARAB, TANINA, ARCHER, FABIENNE, ATKIN-SMITH, GEORGIA K., AYRE, D. CRAIG, BACH, JEAN-MARIE, BACHURSKI, DANIEL, BAHARVAND, HOSSEIN, BALAJ, LEONORA, BALDACCHINO, SHAWN, BAUER, NATALIE N., BAXTER, AMY A., BEBAWY, MARY, BECKHAM, CARLA, ZAVEC, APOLONIJA BEDINA, BENMOUSSA, ABDERRAHIM, BERARDI, ANNA C., BERGESE, PAOLO, BIELSKA, EWA, BLENKIRON, CHERIE, BOBIS-WOZOWICZ, SYLWIA, BOILARD, ERIC, BOIREAU, WILFRID, BONGIOVANNI, ANTONELLA, BORRAS, FRANCESC E., BOSCH, STEFFI, BOULANGER, CHANTAL M., BREAKEFIELD, XANDRA, BREGLIO, ANDREW M., BRENNAN, MEADHBH A., BRIGSTOCK, DAVID R., BRISSON, ALAIN, BROEKMAN, MARIKE L. D., BROMBERG, JACQUELINE F., BRYL-GORECKA, PAULINA, BUCH, SHILPA, BUCK, AMY H., BURGER, DYLAN, BUSATTO, SARA, BUSCHMANN, DOMINIK, BUSSOLATI, BENEDETTA, BUZAS, EDIT, I, BYRD, JAMES BRYAN, CAMUSSI, GIOVANNI, CARTER, DAVID R. F., CARUSO, SARAH, CHAMLEY, LAWRENCE W., CHANG, YU-TING, CHEN, CHIHCHEN, CHEN, SHUAI, CHENG, LESLEY, CHIN, ANDREW R., CLAYTON, ALED, CLERICI, STEFANO P., COCKS, ALEX, COCUCCI, EMANUELE, COFFEY, ROBERT J., CORDEIRO-DA-SILVA, ANABELA, COUCH, YVONNE, COUMANS, FRANK A. W., COYLE, BETH, CRESCITELLI, ROSSELLA, CRIADO, MIRIA FERREIRA, D'SOUZA-SCHOREY, CRISLYN, DAS, SAUMYA, CHAUDHURI, AMRITA DATTA, DE CANDIA, PAOLA, DE SANTANA JUNIOR, ELIEZER F., DE WEVER, OLIVIER, DEL PORTILLO, HERNANDO A., DEMARET, TANGUY, DEVILLE, SARAH, DEVITT, ANDREW, DHONDT, BERT, DI VIZIO, DOLORES, DIETERICH, LOTHAR C., DOLO, VINCENZA, DOMINGUEZ RUBIO, ANA PAULA, DOMINICI, MASSIMO, DOURADO, MAURICIO R., DRIEDONKS, TOM A. P., DUARTE, FILIPE, V, DUNCAN, HEATHER M., EICHENBERGER, RAMON M., EKSTROM, KARIN, ANDALOUSSI, SAMIR E. L., ELIE-CAILLE, CELINE, ERDBRUGGER, UTA, FALCON-PEREZ, JUAN M., FATIMA, FARAH, FISH, JASON E., FLORES-BELLVER, MIGUEL, FORSONITS, ANDRAS, FRELET-BARRAND, ANNIE, FRICKE, FABIA, FUHRMANN, GREGOR, GABRIELSSON, SUSANNE, GAMEZ-VALERO, ANA, GARDINER, CHRIS, GAERTNER, KATHRIN, GAUDIN, RAPHAEL, GHO, YONG SONG, GIEBEL, BERND, GILBERT, CAROLINE, GIMONA, MARIO, GIUSTI, ILARIA, GOBERDHAN, DEBORAH C., I, GOERGENS, ANDRE, GORSKI, SHARON M., GREENING, DAVID W., GROSS, JULIA CHRISTINA, GUALERZI, ALICE, GUPTA, GOPAL N., GUSTAFSON, DAKOTA, HANDBERG, AASE, HARASZTI, REKA A., HARRISON, PAUL, HEGYESI, HARGITA, HENDRIX, AN, HILL, ANDREW F., HOCHBERG, FRED H., HOFFMANN, KARL F., HOLDER, BETH, HOLTHOFER, HARRY, HOSSEINKHANI, BAHARAK, HU, GUOKU, HUANG, YIYAO, HUBER, VERONICA, HUNT, STUART, IBRAHIM, AHMED GAMAL-ELDIN, IKEZU, TSUNEYA, INAL, JAMEEL M., ISIN, MUSTAFA, IVANOVA, ALENA, JACKSON, HANNAH K., JACOBSEN, SOREN, JAY, STEVEN M., JAYACHANDRAN, MUTHUVEL, JENSTER, GUIDO, JIANG, LANZHOU, JOHNSON, SUZANNE M., JONES, JENNIFER C., JONG, AMBROSE, JOVANOVIC-TALISMAN, TIJANA, JUNG, STEPHANIE, KALLURI, RAGHU, KANO, SHIN-ICHI, KAUR, SUKHBIR, KAWAMURA, YUMI, KELLER, EVAN T., KHAMARI, DELARAM, KHOMYAKOVA, ELENA, KHVOROVA, ANASTASIA, KIERULF, PETER, KIM, KWANG PYO, KISLINGER, THOMAS, KLINGEBORN, MIKAEL, KLINKE, DAVID J., II, KORNEK, MIROSLAW, KOSANOVIC, MAJA M., KOVACS, ARPAD FERENC, KRAEMER-ALBERS, EVA-MARIA, KRASEMANN, SUSANNE, KRAUSE, MIRJA, KUROCHKIN, IGOR, V, KUSUMA, GINA D., KUYPERS, SOREN, LAITINEN, SAARA, LANGEVIN, SCOTT M., LANGUINO, LUCIA R., LANNIGAN, JOANNE, LASSER, CECILIA, LAURENT, LOUISE C., LAVIEU, GREGORY, LAZARO-IBANEZ, ELISA, LE LAY, SOAZIG, LEE, MYUNG-SHIN, LEE, YI XIN FIONA, LEMOS, DEBORA S., LENASSI, METKA, LESZCZYNSKA, ALEKSANDRA, LI, ISAAC T. S., LIAO, KE, LIBREGTS, STEN F., LIGETI, ERZSEBET, LIM, REBECCA, LIM, SAI KIANG, LINE, AIJA, LINNEMANNSTOENS, KAREN, LLORENTE, ALICIA, LOMBARD, CATHERINE A., LORENOWICZ, MAGDALENA J., LORINCZ, AKOS M., LOTVALL, JAN, LOVETT, JASON, LOWRY, MICHELLE C., LOYER, XAVIER, LU, QUAN, LUKOMSKA, BARBARA, LUNAVAT, TARAL R., MAAS, SYBREN L. N., MALHI, HARMEET, MARCILLA, ANTONIO, MARIANI, JACOPO, MARISCAL, JAVIER, MARTENS-UZUNOVA, ELENA S., MARTIN-JAULAR, LORENA, MARTINEZ, M. CARMEN, MARTINS, VILMA REGINA, MATHIEU, MATHILDE, MATHIVANAN, SURESH, MAUGERI, MARCO, MCGINNIS, LYNDA K., MCVEY, MARK J., MECKES, DAVID G., JR., MEEHAN, KATIE L., MERTENS, INGE, MINCIACCHI, VALENTINA R., MOLLER, ANDREAS, JORGENSEN, MALENE MOLLER, MORALES-KASTRESANA, AIZEA, MORHAYIM, JESS, MULLIER, FRANCOIS, MURACA, MAURIZIO, MUSANTE, LUCA, MUSSACK, VERONIKA, MUTH, DILLON C., MYBURGH, KATHRYN H., NAJRANA, TANBIR, NAWAZ, MUHAMMAD, NAZARENKO, IRINA, NEJSUM, PETER, NERI, CHRISTIAN, NERI, TOMMASO, NIEUWLAND, RIENK, NIMRICHTER, LEONARDO, NOLAN, JOHN P., NOLTE-'T HOEN, ESTHER N. M., HOOTEN, NICOLE NOREN, O'DRISCOLL, LORRAINE, O'GRADY, TINA, O'LOGHLEN, ANA, OCHIYA, TAKAHIRO, OLIVIER, MARTIN, ORTIZ, ALBERTO, ORTIZ, LUIS A., OSTEIKOETXEA, XABIER, OSTEGAARD, OLE, OSTROWSKI, MATIAS, PARK, JAESUNG, PEGTEL, D. MICHIEL, PEINADO, HECTOR, PERUT, FRANCESCA, PFAFFL, MICHAEL W., PHINNEY, DONALD G., PIETERS, BARTIJN C. H., PINK, RYAN C., PISETSKY, DAVID S., VON STRANDMANN, ELKE POGGE, POLAKOVICOVA, IVA, POON, IVAN K. H., POWELL, BONITA H., PRADA, ILARIA, PULLIAM, LYNN, QUESENBERRY, PETER, RADEGHIERI, ANNALISA, RAFFAI, ROBERT L., RAIMONDO, STEFANIA, RAK, JANUSZ, RAMIREZ, MARCEL, I, RAPOSO, GRACA, RAYYAN, MORSI S., REGEV-RUDZKI, NETA, RICKLEFS, FRANZ L., ROBBINS, PAUL D., ROBERTS, DAVID D., RODRIGUES, SILVIA C., ROHDE, EVA, ROME, SOPHIE, ROUSCHOP, KASPER M. A., RUGHETTI, AURELIA, RUSSELL, ASHLEY E., SAA, PAULA, SAHOO, SUSMITA, SALAS-HUENULEO, EDISON, SANCHEZ, CATHERINE, SAUGSTAD, JULIE A., SAUL, MEIKE J., SCHIFFELERS, RAYMOND M., SCHNEIDER, RAPHAEL, SCHOYEN, TINE HIORTH, SCOTT, AARON, SHAHAJ, ERIOMINA, SHARMA, SHIVANI, SHATNYEVA, OLGA, SHEKARI, FAEZEH, SHELKE, GANESH VILAS, SHETTY, ASHOK K., SHIBA, KIYOTAKA, SILJANDER, PIA R-M, SILVA, ANDREIA M., SKOWRONEK, AGATA, SNYDER, ORMAN L., II, SOARES, RODRIGO PEDRO, SODAR, BARBARA W., SOEKMADJI, CAROLINA, SOTILLO, JAVIER, STAHL, PHILIP D., STOORVOGEL, WILLEM, STOTT, SHANNON L., STRASSER, ERWIN F., SWIFT, SIMON, TAHARA, HIDETOSHI, TEWARI, MUNEESH, TIMMS, KATE, TIWARI, SWASTI, TIXEIRA, ROCHELLE, TKACH, MERCEDES, TOH, WEI SEONG, TOMASINI, RICHARD, TORRECILHAS, ANA CLAUDIA, PABLO TOSAR, JUAN, TOXAVIDIS, VASILIS, URBANELLI, LORENA, VADER, PIETER, VAN BALKOM, BAS W. M., VAN DER GREIN, SUSANNE G., VAN DEUN, JAN, VAN HERWIJNEN, MARTIJN J. C., VAN KEUREN-JENSEN, KENDALL, VAN NIEL, GUILLAUME, VAN ROYEN, MARTIN E., VAN WIJNEN, ANDRE J., HELENA VASCONCELOS, M., VECHETTI, IVAN J., JR., VEIT, TIAGO D., VELLA, LAURA J., VELOT, EMILIE, VERWEIJ, FREDERIK J., VESTAD, BEATE, VINAS, JOSE L., VISNOVITZ, TAMAS, VUKMAN, KRISZTINA V., WAHLGREN, JESSICA, WATSON, DIONYSIOS C., WAUBEN, MARCA H. M., WEAVER, ALISSA, WEBBER, JASON P., WEBER, VIKTORIA, WEHMAN, ANN M., WEISS, DANIEL J., WELSH, JOSHUA A., WENDT, SEBASTIAN, WHEELOCK, ASA M., WIENER, ZOLTAN, WITTE, LEONIE, WOLFRAM, JOY, XAGORARI, ANGELIKI, XANDER, PATRICIA, XU, JING, YAN, XIAOMEI, YANEZ-MO, MARIA, YIN, HANG, YUANA, YUANA, ZAPPULLI, VALENTINA, ZARUBOVA, JANA, ZEKAS, VYTAUTAS, ZHANG, JIAN-YE, ZHAO, ZEZHOU, ZHENG, LEI, ZHEUTLIN, ALEXANDER R., ZICKLER, ANTJE M., ZIMMERMANN, PASCALE, ZIVKOVIC, ANGELA M., ZOCCO, DAVIDE and ZUBA-SURMA, EWA K., 2018. JOURNAL OF EXTRACELLULAR VESICLES. 7(1),
• RAMSAWHOOK A, LEWIS L, COYLE B and RUZOV A, 2017. Clinical epigenetics. 9, 18

• View all publications

Current Research

My research is mainly focused on two specific types of children's brain tumours: medulloblastoma and ependymoma both of which are inherently drug resistant. I am interested in the link between drug resistance and cell migration (metastasis or local invasion). In order to understand cell migration and reflect the levels of drug resistance seen in patient brains we need to use models that accurately model the tumour microenvironment. We are developing 3D models either as spheroids or tumour cells/clusters embedded in basement membrane extract or tailored hydrogels.

Past Research

Before joining the CBTRC I worked at the MRC Toxicology unit in Leicester, investigating the transcriptional response to apoptotic inducing agents.The most informative system proved to be transforming growth factor-beta₁ (罢骋贵尾₁)-induced apoptosis in FaO hepatoma. Although TGF尾₁ acts via the SMAD signaling pathway to initiate de novo gene transcription, little was known about the downstream gene targets that are involved in the regulation of apoptosis. By data mining and cluster analysis of expression data I was able to identify an early response set of nine down-regulated genes that are involved in antioxidant defence that may in fact represent the primary mechanism through which TGF尾₁ initiates apoptosis.

Prior to that I started my postdoctoral career in the Department of Genetics at the University of Leicester. I investigated the genetic basis of Pendred Syndrome, an autosomal recessive disorder associated with developmental abnormalities of the cochlea, sensorineural hearing loss, and diffuse thyroid enlargement. Using linkage analysis I identified the pendrin gene then 78% of the underlying mutations in 31 affected families. My PhD at the MRC Human Genetics Unit in Edinburgh was also focused on mapping and mutational analysis of another deafness disorder (Usher Syndrome Type IB).

Future Research

In future we would like to produce more sophisticated models that include immune cells.

• AHMED EM, BANDOPADHYAY G, COYLE B and GRABOWSKA A, 2018. Cellular oncology (Dordrecht). 41(3), 319-328
• 2018. Frontiers in Cell and Developmental Biology. 6, 26
• THERY, CLOTILDE, WITWER, KENNETH W., AIKAWA, ELENA, JOSE ALCARAZ, MARIA, ANDERSON, JOHNATHON D., ANDRIANTSITOHAINA, RAMAROSON, ANTONIOU, ANNA, ARAB, TANINA, ARCHER, FABIENNE, ATKIN-SMITH, GEORGIA K., AYRE, D. CRAIG, BACH, JEAN-MARIE, BACHURSKI, DANIEL, BAHARVAND, HOSSEIN, BALAJ, LEONORA, BALDACCHINO, SHAWN, BAUER, NATALIE N., BAXTER, AMY A., BEBAWY, MARY, BECKHAM, CARLA, ZAVEC, APOLONIJA BEDINA, BENMOUSSA, ABDERRAHIM, BERARDI, ANNA C., BERGESE, PAOLO, BIELSKA, EWA, BLENKIRON, CHERIE, BOBIS-WOZOWICZ, SYLWIA, BOILARD, ERIC, BOIREAU, WILFRID, BONGIOVANNI, ANTONELLA, BORRAS, FRANCESC E., BOSCH, STEFFI, BOULANGER, CHANTAL M., BREAKEFIELD, XANDRA, BREGLIO, ANDREW M., BRENNAN, MEADHBH A., BRIGSTOCK, DAVID R., BRISSON, ALAIN, BROEKMAN, MARIKE L. D., BROMBERG, JACQUELINE F., BRYL-GORECKA, PAULINA, BUCH, SHILPA, BUCK, AMY H., BURGER, DYLAN, BUSATTO, SARA, BUSCHMANN, DOMINIK, BUSSOLATI, BENEDETTA, BUZAS, EDIT, I, BYRD, JAMES BRYAN, CAMUSSI, GIOVANNI, CARTER, DAVID R. F., CARUSO, SARAH, CHAMLEY, LAWRENCE W., CHANG, YU-TING, CHEN, CHIHCHEN, CHEN, SHUAI, CHENG, LESLEY, CHIN, ANDREW R., CLAYTON, ALED, CLERICI, STEFANO P., COCKS, ALEX, COCUCCI, EMANUELE, COFFEY, ROBERT J., CORDEIRO-DA-SILVA, ANABELA, COUCH, YVONNE, COUMANS, FRANK A. W., COYLE, BETH, CRESCITELLI, ROSSELLA, CRIADO, MIRIA FERREIRA, D'SOUZA-SCHOREY, CRISLYN, DAS, SAUMYA, CHAUDHURI, AMRITA DATTA, DE CANDIA, PAOLA, DE SANTANA JUNIOR, ELIEZER F., DE WEVER, OLIVIER, DEL PORTILLO, HERNANDO A., DEMARET, TANGUY, DEVILLE, SARAH, DEVITT, ANDREW, DHONDT, BERT, DI VIZIO, DOLORES, DIETERICH, LOTHAR C., DOLO, VINCENZA, DOMINGUEZ RUBIO, ANA PAULA, DOMINICI, MASSIMO, DOURADO, MAURICIO R., DRIEDONKS, TOM A. P., DUARTE, FILIPE, V, DUNCAN, HEATHER M., EICHENBERGER, RAMON M., EKSTROM, KARIN, ANDALOUSSI, SAMIR E. L., ELIE-CAILLE, CELINE, ERDBRUGGER, UTA, FALCON-PEREZ, JUAN M., FATIMA, FARAH, FISH, JASON E., FLORES-BELLVER, MIGUEL, FORSONITS, ANDRAS, FRELET-BARRAND, ANNIE, FRICKE, FABIA, FUHRMANN, GREGOR, GABRIELSSON, SUSANNE, GAMEZ-VALERO, ANA, GARDINER, CHRIS, GAERTNER, KATHRIN, GAUDIN, RAPHAEL, GHO, YONG SONG, GIEBEL, BERND, GILBERT, CAROLINE, GIMONA, MARIO, GIUSTI, ILARIA, GOBERDHAN, DEBORAH C., I, GOERGENS, ANDRE, GORSKI, SHARON M., GREENING, DAVID W., GROSS, JULIA CHRISTINA, GUALERZI, ALICE, GUPTA, GOPAL N., GUSTAFSON, DAKOTA, HANDBERG, AASE, HARASZTI, REKA A., HARRISON, PAUL, HEGYESI, HARGITA, HENDRIX, AN, HILL, ANDREW F., HOCHBERG, FRED H., HOFFMANN, KARL F., HOLDER, BETH, HOLTHOFER, HARRY, HOSSEINKHANI, BAHARAK, HU, GUOKU, HUANG, YIYAO, HUBER, VERONICA, HUNT, STUART, IBRAHIM, AHMED GAMAL-ELDIN, IKEZU, TSUNEYA, INAL, JAMEEL M., ISIN, MUSTAFA, IVANOVA, ALENA, JACKSON, HANNAH K., JACOBSEN, SOREN, JAY, STEVEN M., JAYACHANDRAN, MUTHUVEL, JENSTER, GUIDO, JIANG, LANZHOU, JOHNSON, SUZANNE M., JONES, JENNIFER C., JONG, AMBROSE, JOVANOVIC-TALISMAN, TIJANA, JUNG, STEPHANIE, KALLURI, RAGHU, KANO, SHIN-ICHI, KAUR, SUKHBIR, KAWAMURA, YUMI, KELLER, EVAN T., KHAMARI, DELARAM, KHOMYAKOVA, ELENA, KHVOROVA, ANASTASIA, KIERULF, PETER, KIM, KWANG PYO, KISLINGER, THOMAS, KLINGEBORN, MIKAEL, KLINKE, DAVID J., II, KORNEK, MIROSLAW, KOSANOVIC, MAJA M., KOVACS, ARPAD FERENC, KRAEMER-ALBERS, EVA-MARIA, KRASEMANN, SUSANNE, KRAUSE, MIRJA, KUROCHKIN, IGOR, V, KUSUMA, GINA D., KUYPERS, SOREN, LAITINEN, SAARA, LANGEVIN, SCOTT M., LANGUINO, LUCIA R., LANNIGAN, JOANNE, LASSER, CECILIA, LAURENT, LOUISE C., LAVIEU, GREGORY, LAZARO-IBANEZ, ELISA, LE LAY, SOAZIG, LEE, MYUNG-SHIN, LEE, YI XIN FIONA, LEMOS, DEBORA S., LENASSI, METKA, LESZCZYNSKA, ALEKSANDRA, LI, ISAAC T. S., LIAO, KE, LIBREGTS, STEN F., LIGETI, ERZSEBET, LIM, REBECCA, LIM, SAI KIANG, LINE, AIJA, LINNEMANNSTOENS, KAREN, LLORENTE, ALICIA, LOMBARD, CATHERINE A., LORENOWICZ, MAGDALENA J., LORINCZ, AKOS M., LOTVALL, JAN, LOVETT, JASON, LOWRY, MICHELLE C., LOYER, XAVIER, LU, QUAN, LUKOMSKA, BARBARA, LUNAVAT, TARAL R., MAAS, SYBREN L. N., MALHI, HARMEET, MARCILLA, ANTONIO, MARIANI, JACOPO, MARISCAL, JAVIER, MARTENS-UZUNOVA, ELENA S., MARTIN-JAULAR, LORENA, MARTINEZ, M. CARMEN, MARTINS, VILMA REGINA, MATHIEU, MATHILDE, MATHIVANAN, SURESH, MAUGERI, MARCO, MCGINNIS, LYNDA K., MCVEY, MARK J., MECKES, DAVID G., JR., MEEHAN, KATIE L., MERTENS, INGE, MINCIACCHI, VALENTINA R., MOLLER, ANDREAS, JORGENSEN, MALENE MOLLER, MORALES-KASTRESANA, AIZEA, MORHAYIM, JESS, MULLIER, FRANCOIS, MURACA, MAURIZIO, MUSANTE, LUCA, MUSSACK, VERONIKA, MUTH, DILLON C., MYBURGH, KATHRYN H., NAJRANA, TANBIR, NAWAZ, MUHAMMAD, NAZARENKO, IRINA, NEJSUM, PETER, NERI, CHRISTIAN, NERI, TOMMASO, NIEUWLAND, RIENK, NIMRICHTER, LEONARDO, NOLAN, JOHN P., NOLTE-'T HOEN, ESTHER N. M., HOOTEN, NICOLE NOREN, O'DRISCOLL, LORRAINE, O'GRADY, TINA, O'LOGHLEN, ANA, OCHIYA, TAKAHIRO, OLIVIER, MARTIN, ORTIZ, ALBERTO, ORTIZ, LUIS A., OSTEIKOETXEA, XABIER, OSTEGAARD, OLE, OSTROWSKI, MATIAS, PARK, JAESUNG, PEGTEL, D. MICHIEL, PEINADO, HECTOR, PERUT, FRANCESCA, PFAFFL, MICHAEL W., PHINNEY, DONALD G., PIETERS, BARTIJN C. H., PINK, RYAN C., PISETSKY, DAVID S., VON STRANDMANN, ELKE POGGE, POLAKOVICOVA, IVA, POON, IVAN K. H., POWELL, BONITA H., PRADA, ILARIA, PULLIAM, LYNN, QUESENBERRY, PETER, RADEGHIERI, ANNALISA, RAFFAI, ROBERT L., RAIMONDO, STEFANIA, RAK, JANUSZ, RAMIREZ, MARCEL, I, RAPOSO, GRACA, RAYYAN, MORSI S., REGEV-RUDZKI, NETA, RICKLEFS, FRANZ L., ROBBINS, PAUL D., ROBERTS, DAVID D., RODRIGUES, SILVIA C., ROHDE, EVA, ROME, SOPHIE, ROUSCHOP, KASPER M. A., RUGHETTI, AURELIA, RUSSELL, ASHLEY E., SAA, PAULA, SAHOO, SUSMITA, SALAS-HUENULEO, EDISON, SANCHEZ, CATHERINE, SAUGSTAD, JULIE A., SAUL, MEIKE J., SCHIFFELERS, RAYMOND M., SCHNEIDER, RAPHAEL, SCHOYEN, TINE HIORTH, SCOTT, AARON, SHAHAJ, ERIOMINA, SHARMA, SHIVANI, SHATNYEVA, OLGA, SHEKARI, FAEZEH, SHELKE, GANESH VILAS, SHETTY, ASHOK K., SHIBA, KIYOTAKA, SILJANDER, PIA R-M, SILVA, ANDREIA M., SKOWRONEK, AGATA, SNYDER, ORMAN L., II, SOARES, RODRIGO PEDRO, SODAR, BARBARA W., SOEKMADJI, CAROLINA, SOTILLO, JAVIER, STAHL, PHILIP D., STOORVOGEL, WILLEM, STOTT, SHANNON L., STRASSER, ERWIN F., SWIFT, SIMON, TAHARA, HIDETOSHI, TEWARI, MUNEESH, TIMMS, KATE, TIWARI, SWASTI, TIXEIRA, ROCHELLE, TKACH, MERCEDES, TOH, WEI SEONG, TOMASINI, RICHARD, TORRECILHAS, ANA CLAUDIA, PABLO TOSAR, JUAN, TOXAVIDIS, VASILIS, URBANELLI, LORENA, VADER, PIETER, VAN BALKOM, BAS W. M., VAN DER GREIN, SUSANNE G., VAN DEUN, JAN, VAN HERWIJNEN, MARTIJN J. 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• RAMSAWHOOK A, LEWIS L, COYLE B and RUZOV A, 2017. Clinical epigenetics. 9, 18
• AL-GHAFARI AB, PUNJARUK W, STORER LC, CARRIER DJ, HUSSEIN D, COYLE B and KERR ID, 2016. Journal of neuro-oncology. 127(3), 455-62
• IVANOV DP, WALKER DA, COYLE B and GRABOWSKA AM, 2016. Data in brief. 9, 696-698
• IVANOV DP, COYLE B, WALKER DA and GRABOWSKA AM, 2016. Journal of biotechnology. 236, 10-25
• COYLE B, KESSLER M, SABNIS DH and KERR ID, 2015. Biochemical Society transactions. 43(5), 1018-22
• OTHMAN RT, KIMISHI I, BRADSHAW TD, STORER LCD, KORSHUNOV A, PFISTER SM, GRUNDY RG, KERR ID and COYLE B, 2014. Acta neuropathologica communications. 2, 57
• ROGERS, HAZEL A., MAYNE, CERYS, CHAPMAN, REBECCA J., KILDAY, JOHN-PAUL, COYLE, BETH and GRUNDY, RICHARD G., 2013. CLINICAL CANCER RESEARCH. 19(23), 6450-6460
• ROGERS, H. A., WARD, J. H., MILLER, S., LOWE, J., COYLE, B. and GRUNDY, R. G., 2013. BRITISH JOURNAL OF CANCER. 108(10), 2130-2141
• ROGERS, H.A., KILDAY, J-P., MAYNE, C., WARD, J., ADAMOWICZ-BRICE, M., SCHWALBE, E.C., CLIFFORD, S.C., COYLE, B. and GRUNDY, R.G., 2012. Acta Neuropathologica. 123(5), 711-725
• KILDAY, J.P., MITRA, B., DOMERG, C., WARD, J., ANDREIUOLO, F., OSTESO-IBANEZ, T., MAUGUEN, A., VARLET, P., LE DELEY, M.C., LOWE, J., ELLISON, D.W., GILBERTSON, R.J., COYLE, B., GRILL, J. and GRUNDY, R.G., 2012. Clinical Cancer Research. 18(7), 2001-2011
• SMITH S.J., TILLY H., WARD J.H., MACARTHUR D.C., LOWE J., COYLE B. and GRUNDY R.G., 2012. Acta Neuropathologica. 124(1), 99-110
• ROGERS, H. A., SOUSA, S., SALTO, C., ARENAS, E., COYLE, B. and GRUNDY, R. G., 2012. BRITISH JOURNAL OF CANCER. 107(7), 1144-1152
• BARROW, J., ADAMOWICZ-BRICE, M., CARTMILL, M., MACARTHUR, D., LOWE, J., ROBSON, K., BRUNDLER, M.A., WALKER, D.A., COYLE, B. and GRUNDY, R., 2011. Neuro-oncology. 13(2), 212-222
• MILLER S, ROGERS HA, LYON P, RAND V, ADAMOWICZ-BRICE M, CLIFFORD SC, HAYDEN JT, DYER S, PFISTER S, KORSHUNOV A, BRUNDLER M, LOWE J, COYLE B and GRUNDY RG, 2011. Neuro-oncology. 13(8), 866-79
• LEVESLEY, J., LUSHER, M.E., LINDSEY, J.C., CLIFFORD, S.C., GRUNDY, R. and COYLE, B., 2011. Neuro-Oncology. 13(12), 1265-1276
• SMITH SJ, LONG A, BARROW JH, MACARTHUR DC, COYLE B, GRUNDY RG and CHILDREN'S CANCER AND LEUKAEMIA GROUP BIOLOGICAL STUDIES COMMITTEE, 2011. Neuro-Oncology. 13(11), 1171-7
• HUSSEIN, D., PUNJARUK, W., STORER, L.C.D., SHAW, L., OTHMAN, R.T., PEET, A., MILLER, S., BANDOPADHYAY, G., HEATH, R., KUMARI, R., BOWMAN, K.J., BRAKER, P., RAHMAN, R., JONES, G.D.D. and WATSON, S., 2010. Neuro-oncology. 13(1), 70-83
• JOHNSON, R.A., WRIGHT, K.D., POPPLETON, H., MOHANKUMAR, K.M., FINKELSTEIN, D., POUNDS, S.B., RAND, V., LEARY, S.E.S., WHITE, E., EDEN, C., HOGG, T., NORTHCOTT, P., MACK, S., NEALE, G. and WANG, Y., 2010. Nature. 466(7306), 632-636
• RAHMAN, R., OSTESO-IBANEZ, T., HIRST, R.A., LEVESLEY, J., KILDAY, J.P., QUINN, S., PEET, A., O'CALLAGHAN, C., COYLE, B. and GRUNDY, R.G., 2010. Molecular Cancer Therapeutics. 9(9), 2568-2581
• BARBARA, S.P., CHUNXU, Q., JONES, C., LIU, Z., ADAMOWICZ-BRICE, M., ZHANG, J., BAX, D.A., COYLE, B., BARROW, J., HARGRAVE, D., LOWE, J., GAJJAR, A., ZHAO, W., BRONISCER, A., ELLISON, D.W., GRUNDY, R.G. and BAKER, S.J., 2010. Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology. 28(18), 3061-3068
• ROGERS, H A, MILLER, S, LOWE, J, BRUNDLER, M-A, COYLE, B and GRUNDY, R G, 2009. British journal of cancer. 100(8), 1292-302
• KILDAY, JOHN-PAUL, RAHMAN, RUMAN, DYER, SARA, RIDLEY, LEE, LOWE, JAMES, COYLE, BETH and GRUNDY, RICHARD, 2009. Molecular cancer research : MCR. 7(6), 765-86
• RIDLEY, L., RAHMAN, R., BRUNDLER, M.A., ELLISON, D., LOWE, J., ROBSON, K., PREBBLE, E., LUCKETT, I., GILBERTSON, R.J., PARKES, S., RAND, V., COYLE, B. and GRUNDY, R.G., 2008. Neuro-Oncology. 10(5), 675-689
• RAND, V, PREBBLE, E, RIDLEY, L, HOWARD, M, WEI, W, BRUNDLER, M-A, FEE, B E, RIGGINS, G J, COYLE, B, GRUNDY, R G and ,, 2008. British journal of cancer. 99(7), 1136-43
• SAVILL, R.M., SCOTTING, P.J. and COYLE, B., 2005. Cerebellum. 4(4), 271-278
• YANG, Z-J., APPLEBY, V.J., COYLE, B., CHAN, W-I., TAHMASEB, M., WIGMORE, P.M. and SCOTTING, P.J, 2004. Journal of Neuroscience Methods. 132(2), 149-160
• ROBERTS, R.A., MICHEL, C., COYLE, B., FREATHY, C., CAIN, K. and BOITIER, E., 2004. Toxicology Letters. 149(1-3), 37-41
• COYLE, B., FREATHY, C., GANT, T.W., ROBERTS, R.A. and CAIN, K., 2003. Journal of Biological Chemistry. 278(8), 5920-5928
• ROBERTS, R., CAIN, K., COYLE, B., FREATHY, C., LEONARD, J.-F. and GAUTIER, J.-C., 2003. Drug Metabolism Reviews. VOL 35(PART 4), 269-276
• COUCKE, P J, VAN HAUWE, P, EVERETT, L A, DEMIRHAN, O, KABAKKAYA, Y, DIETRICH, N L, SMITH, R J, COYLE, E, REARDON, W, TREMBATH, R, WILLEMS, P J, GREEN, E D and VAN CAMP, G, 1999. Identification of two different mutations in the PDS gene in an inbred family with Pendred syndrome. Journal of medical genetics. 36(6), 475-7
• VAIDYA, B, COFFEY, R, COYLE, B, TREMBATH, R, SAN LAZARO, C, REARDON, W and KENDALL-TAYLOR, P, 1999. The Journal of clinical endocrinology and metabolism. 84(8), 2736-8
• HAILA, S, H脰GLUND, P, SCHERER, S W, LEE, J R, KRISTO, P, COYLE, B, TREMBATH, R, HOLMBERG, C, DE LA CHAPELLE, A and KERE, J, 1998. Gene. 214(1-2), 87-93
• COYLE, B, REARDON, W, HERBRICK, J A, TSUI, L C, GAUSDEN, E, LEE, J, COFFEY, R, GRUETERS, A, GROSSMAN4, A, PHELPS, P D, LUXON, L, KENDALL-TAYLOR, P, SCHERER, S W and TREMBATH, R C, 1998. Human molecular genetics. 7(7), 1105-12
• GAUSDEN, E, COYLE, B, ARMOUR, J A, COFFEY, R, GROSSMAN, A, FRASER, G R, WINTER, R M, PEMBREY, M E, KENDALL-TAYLOR, P, STEPHENS, D, LUXON, L M, PHELPS, P D, REARDON, W and TREMBATH, R, 1997. Journal of medical genetics. 34(2), 126-9
• GAUSDEN, E, ARMOUR, J A, COYLE, B, COFFEY, R, HOCHBERG, Z, PEMBREY, M, BRITTON, K E, GROSSMAN, A, REARDON, W and TREMBATH, R, 1996. Clinical endocrinology. 44(4), 441-6
• COYLE, B, COFFEY, R, ARMOUR, J A, GAUSDEN, E, HOCHBERG, Z, GROSSMAN, A, BRITTON, K, PEMBREY, M, REARDON, W and TREMBATH, R, 1996. Nature genetics. 12(4), 421-3