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Mathew Piasecki

Associate Professor, Faculty of Medicine & Health Sciences

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Biography

This research focuses on the structural and functional remodelling of motor units in ageing and disease.This involves the application of intramusuclar and high density surface electromyography (EMG) in human trials, and the decoding of neural drive to muscle during active contraction.

Expertise Summary

Ageing

Sarcopenia

Neuromuscular function

Electromyography

Teaching Summary

I teach on a variety of topics on both the Graduate Entry Medical Course and the BSc in Medical Physiology and Therapeutics.

Research Summary

Neuromuscular function in ageing and disease

Motoneuron function

Neural drive

Intramuscular and high density surface electromyography

Recent Publications

  • JONES EJ, GUO Y, MARTINEZ-VALDES E, NEGRO F, STASHUK DW, ATHERTON PJ, PHILLIPS BE and PIASECKI M, 2023. Exp Physiol. 108(6), 827-837
  • JONES EJ, ATHERTON PJ, PIASECKI M and PHILLIPS BE, 2023. Exp Physiol. 108(4), 549-553
  • ELLWOOD, REBECCA A, SLADE, LUKE, LEWIS, JONATHAN, TORREGROSSA, ROBERTA, SUDEVAN, SURABHI, PIASECKI, MATHEW, WHITEMAN, MATTHEW, ETHERIDGE, TIMOTHY and SZEWCZYK, NATHANIEL J, 2022. Sulfur amino acid supplementation displays therapeutic potential in a C. elegans model of Duchenne muscular dystrophy. Communications biology. 5(1), 1255
  • HARDY, EDWARD J., HATT, JACOB, DOLEMAN, BRETT, SMART, THOMAS F., PIASECKI, MATTHEW, LUND, JONATHAN N. and PHILLIPS, BETHAN E., 2022. Post-operative electrical muscle stimulation attenuates loss of muscle mass and function following major abdominal surgery in older adults: a split body randomised control trial AGE AND AGEING. 51(10),
  • JONES EJ, GUO Y, MARTINEZ-VALDES E, NEGRO F, STASHUK DW, ATHERTON PJ, PHILLIPS BE and PIASECKI M, 2023. Exp Physiol. 108(6), 827-837
  • JONES EJ, ATHERTON PJ, PIASECKI M and PHILLIPS BE, 2023. Exp Physiol. 108(4), 549-553
  • ELLWOOD, REBECCA A, SLADE, LUKE, LEWIS, JONATHAN, TORREGROSSA, ROBERTA, SUDEVAN, SURABHI, PIASECKI, MATHEW, WHITEMAN, MATTHEW, ETHERIDGE, TIMOTHY and SZEWCZYK, NATHANIEL J, 2022. Sulfur amino acid supplementation displays therapeutic potential in a C. elegans model of Duchenne muscular dystrophy. Communications biology. 5(1), 1255
  • HARDY, EDWARD J., HATT, JACOB, DOLEMAN, BRETT, SMART, THOMAS F., PIASECKI, MATTHEW, LUND, JONATHAN N. and PHILLIPS, BETHAN E., 2022. Post-operative electrical muscle stimulation attenuates loss of muscle mass and function following major abdominal surgery in older adults: a split body randomised control trial AGE AND AGEING. 51(10),
  • GUO, Y., JONES, E. J., INNS, T. B., PHILLIPS, B. E., ATHERTON, P. J. and PIASECKI, M., 2022. Reduced amplitude of persistent inward currents in the aged human vastus lateralis ACTA PHYSIOLOGICA. 236, 357-359
  • JONES, E. J., GUO, Y., ATHERTON, P., PHILLIPS, B. E. and PIASECKI, M., 2022. Motor unit firing rate variability and microvascular blood flow as mediators of neuromuscular control. ACTA PHYSIOLOGICA. 236, 142-143
  • GHARAHDAGHI, N., GUO, Y., RUDRAPPA, S., PHILLIPS, B. E., IDRIS, I., WILKINSON, D. J., SZEWCZYK, N. J., SMITH, K., PIASECKI, M. and ATHERTON, P. J., 2022. Distinct gene expression signatures of the aged human neuromuscular junction ACTA PHYSIOLOGICA. 236, 133-133
  • BOLLEN, S. E., BASS, J. J., CROSSLAND, H., PIASECKI, J., MCPHEE, J. S., PIASECKI, M., WILKINSON, D. J., HEWISON, M. and ATHERTON, P. J., 2022. The association of vitamin D binding protein gene (GC) single nucleotide polymorphisms with skeletal muscle function and performance in master athletes. ACTA PHYSIOLOGICA. 236, 365-367
  • INNS, THOMAS B., BASS, JOSEPH J., HARDY, EDWARD J. O., WILKINSON, DANIEL J., STASHUK, DANIEL W., ATHERTON, PHILIP J., PHILLIPS, BETHAN E. and PIASECKI, MATHEW, 2022. Motor unit dysregulation following 15 days of unilateral lower limb immobilisation JOURNAL OF PHYSIOLOGY-LONDON. 600(21), 4753-4769
  • ELY, ISABEL A., JONES, ELEANOR J., INNS, THOMAS B., DOOLEY, SIOBHRA, MILLER, SARAH B. J., STASHUK, DANIEL W., ATHERTON, PHILIP J., PHILLIPS, BETHAN E. and PIASECKI, MATHEW, 2022. Training-induced improvements in knee extensor force accuracy are associated with reduced vastus lateralis motor unit firing variability EXPERIMENTAL PHYSIOLOGY. 107(9), 1061-1070
  • GUO, YUXIAO, PIASECKI, JESSICA, SWIECICKA, AGNIESZKA, IRELAND, ALEX, PHILLIPS, BETHAN E., ATHERTON, PHILIP J., STASHUK, DANIEL, RUTTER, MARTIN K., MCPHEE, JAMIE S. and PIASECKI, MATHEW, 2022. Circulating testosterone and dehydroepiandrosterone are associated with individual motor unit features in untrained and highly active older men GEROSCIENCE. 44(3), 1215-1228
  • SMART TFF, DOLEMAN B, HATT J, PAUL M, TOFT S, LUND JN and PHILLIPS BE, 2022. Age Ageing. 51(6), afac143
  • GUO Y, JONES EJ, INNS TB, ELY IA, STASHUK DW, WILKINSON DJ, SMITH K, PIASECKI J, PHILLIPS BE, ATHERTON PJ and PIASECKI M, 2022. Acta Physiol (Oxf). 235(2), e13803
  • JONES EJ, CHIOU SY, ATHERTON PJ, PHILLIPS BE and PIASECKI M, 2022. J Physiol. 600(8), 1839-1849
  • GLADMAN JFR, PIASECKI M, CHADBORN N and FROST K, 2022. In: BRC MSK Conference.
  • INNS, THOMAS, BASS, JOSEPH, HARDY, EDWARD, STASHUK, DANIEL, ATHERTON, PHILIP, PHILLIPS, BETHAN and PIASECKI, MATHEW, 2021. The impact of quadriceps disuse atrophy on motor unit properties FASEB JOURNAL. 35,
  • GUO, YUXIAO, PIASECKI, JESSICA, SWIECICKA, AGNIESZKA, IRELAND, ALEX, PHILLIPS, BETHAN, ATHERTON, PHILIP, STASHUK, DANIEL, RUTTER, MARTIN, MCPHEE, JAMIE and PIASECKI, MATHEW, 2021. Circulating Dehydroepiandrosterone and Testosterone are Differentially Associated with Motor Unit Function in Young and Masters Athletes FASEB JOURNAL. 35,
  • JONES, ELEANOR, MARTINEZ-VALDES, EDUARDO, NEGRO, FRANCESCO, MCCORMICK, DANIEL, ATHERTON, PHILIP, PHILLIPS, BETHAN and PIASECKI, MATHEW, 2021. Tracking of Individual Motor Units Following Concentric and Eccentric Exercise-induced Fatigue Reveals Contraction-type Specific Changes in Discharge Properties FASEB JOURNAL. 35,
  • CROSSLAND, HANNAH, PIASECKI, JESSICA, MCCORMICK, DANIEL, PHILLIPS, BETHAN E., WILKINSON, DANIEL J., SMITH, KENNETH, MCPHEE, JAMIE S., PIASECKI, MATHEW and ATHERTON, PHILIP J., 2020. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 319(2), R184-R194
  • MESSA, GUY A. M., PIASECKI, MATHEW, RITTWEGER, JOERN, MCPHEE, JAMIE S., KOLTAI, ERIKA, RADAK, ZSOLT, SIMUNIC, BOSTJAN, HEINONEN, ARI, SUOMINEN, HARRI, KORHONEN, MARKO T. and DEGENS, HANS, 2020. SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS.
  • SWIECICKA, AGNIESZKA, PIASECKI, MATHEW, STASHUK, DANIEL, JONES, DAVID, WU, FREDERICK, MCPHEE, JAMIE S. and RUTTER, MARTIN K., 2020. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 105(7), E2358-E2368
  • MESSA, GUY A. M., PIASECKI, MATHEW, HURST, JOSH, HILL, CAMERON, TALLIS, JASON and DEGENS, HANS, 2020. JOURNAL OF EXPERIMENTAL BIOLOGY. 223(6),
  • PIASECKI, JESSICA, INNS, THOMAS B, BASS, JOSEPH J, SCOTT, REECE, STASHUK, DANIEL W, PHILLIPS, BETHAN E, ATHERTON, PHILIP J and PIASECKI, MATHEW, 2020. The Journal of physiology.
  • GUO Y, PHILLIPS BE, ATHERTON PJ and PIASECKI M, 2020. Mech Ageing Dev. 193, 111402
  • SWIECICKA, AGNIESZKA, PIASECKI, MATHEW, STASHUK, DANIEL W, IRELAND, ALEX, JONES, DAVID A, RUTTER, MARTIN K and MCPHEE, JAMIE S, 2019. Experimental physiology.
  • PIASECKI, M., IRELAND, A., PIASECKI, J., DEGENS, H., STASHUK, D. W., SWIECICKA, A., RUTTER, M. K., JONES, D. A. and MCPHEE, J. S., 2019. FRONTIERS IN PHYSIOLOGY. 10,
  • AL-DABBAGH, SARAH, MCPHEE, JAMIE S., PIASECKI, MATHEW, STEWART, CLAIRE E. and AL-SHANTI, NASSER, 2019. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 74(9), 1375-1385
  • MESSA, G. A. M., PIASECKI, M., HILL, C., MCPHEE, J. S., TALLIS, J. and DEGENS, H., 2019. EXPERIMENTAL GERONTOLOGY. 125,
  • PIASECKI M, IRELAND A, PIASECKI J, STASHUK DW, SWIECICKA A, RUTTER MK, JONES DA and MCPHEE JS, 2018. The Journal of physiology.
  • PIASECKI M, IRELAND A, PIASECKI J, STASHUK DW, MCPHEE JS and JONES DA, 2018. European journal of applied physiology. 118(4), 767-775
  • MCPHEE JS, CAMERON J, MADEN-WILKINSON T, PIASECKI M, YAP MH, JONES DA and DEGENS H, 2018. The journals of gerontology. Series A, Biological sciences and medical sciences. (In Press.)
  • PIASECKI J, IRELAND A, PIASECKI M, CAMERON J, MCPHEE JS and DEGENS H, 2018. Scandinavian journal of medicine & science in sports. 28(5), 1559-1568
  • YEUNG, SUEY S. Y., REIJNIERSE, ESMEE M., TRAPPENBURG, MARIJKE C., HOGREL, JEAN-YVES, MCPHEE, JAMIE S., PIASECKI, MATHEW, SIPILA, SARIANNA, SALPAKOSKI, ANU, BUTLER-BROWNE, GILLIAN, PAASUKE, MATI, GAPEYEVA, HELENA, NARICI, MARCO, V, MESKERS, CAREL G. M. and MAIER, ANDREA B., 2018. JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 19(8), 703-709
  • PIASECKI, J., MCPHEE, J. S., HANNAM, K., DEERE, K. C., ELHAKEEM, A., PIASECKI, M., DEGENS, H., TOBIAS, J. H. and IRELAND, A., 2018. ARCHIVES OF OSTEOPOROSIS. 13(1),
  • WILKINSON DJ, PIASECKI M and ATHERTON PJ, 2018. Ageing Res Rev. 47, 123-132
  • AL-DABBAGH S, MCPHEE JS, PIASECKI M, STEWART CE and AL-SHANTI N, 2018. The journals of gerontology. Series A, Biological sciences and medical sciences. (In Press.)
  • FRANCIS P, LYONS M, PIASECKI M, MC PHEE J, HIND K and JAKEMAN P, 2017. Biogerontology. 18(6), 901-911
  • PANN脡REC A, SPRINGER M, MIGLIAVACCA E, IRELAND A, PIASECKI M, KARAZ S, JACOT G, M脡TAIRON S, DANENBERG E, RAYMOND F, DESCOMBES P, MCPHEE JS and FEIGE JN, 2016. Aging. 8(4), 712-29
  • LEIGHTLEY D, YAP MH, COULSON J, PIASECKI M, CAMERON J, BARNOUIN Y, TOBIAS J and MCPHEE JS, 2016. Journal of aging and physical activity. 25(3), 345-350
  • PIASECKI M, IRELAND A, COULSON J, STASHUK DW, HAMILTON-WRIGHT A, SWIECICKA A, RUTTER MK, MCPHEE JS and JONES DA, 2016. Physiological reports. 4(19),
  • BAGLEY, LIAM, SLEVIN, MARK, BRADBURN, STEVEN, LIU, DONGHUI, MURGATROYD, CHRIS, MORRISSEY, GEORGE, CARROLL, MICHAEL, PIASECKI, MATHEW, GILMORE, WILLIAM S and MCPHEE, JAMIE S, 2016. 2max during exercise. BMJ open sport & exercise medicine. 2(1), e000056
  • PIASECKI M, IRELAND A, STASHUK D, HAMILTON-WRIGHT A, JONES DA and MCPHEE JS, 2015. The Journal of physiology. 594(16), 4525-36
  • PIASECKI M, IRELAND A, JONES DA and MCPHEE JS, 2015. Biogerontology. 17(3), 485-96
  • VERLAAN S, ASPRAY TJ, BAUER JM, CEDERHOLM T, HEMSWORTH J, HILL TR, MCPHEE JS, PIASECKI M, SEAL C, SIEBER CC, TER BORG S, WIJERS SL and BRANDT K, 2015. Clinical nutrition (Edinburgh, Scotland). 36(1), 267-274

School of Medicine

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