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School of Biosciences
 

Image of Ravinder Anand-Ivell

Ravinder Anand-Ivell

Director of Postgraduate and Postdoctoral Research, & Associate Professor in Endocrinology and Reproductive Physiology, Faculty of Science

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Biography

Ravinder is researching the hormone systems which govern fertility and reproductive health in men and women, as well as in domestic and other species, and is particularly interested in how early life experience, including lifestyle and nutrition, can dictate the health of an individual later in life and during ageing. Ravinder is also engaged in the development of a number of novel assay systems supporting both human and veterinary clinical science. Besides reproduction, Ravinder is interested in developing and understanding novel cell-based models for evaluating other tissues, including kidney and adrenal functions. She brings with her a long international experience of research, teaching and supervision from Europe, Asia, and Australia.

At various undergraduate and postgraduate levels, Ravinder teaches modules on Reproduction, Endocrine Systems, and Antibody Biotechnology. She is a firm believer in using research to inform her teaching. Ravinder supervises researchers at all levels (UG, PG, postdoc, senior scientist and internship candidates).

Expertise Summary

Research Keywords

  • Health across the lifespan
  • Reproductive physiology and fertility
  • Cells and Hormones
  • Lifestyle, nutrition, and healthy ageing
  • Environmental endocrine disruption

Expertise

  • Endocrinology and physiology of male and female reproduction in humans and domestic species, looking at foetal development, as well as puberty and adult function, including ageing.
  • Cell culture and molecular analysis of primary and secondary cell systems from human and domestic species, with emphasis on both male and female reproductive physiology and their regulation.
  • Cell signalling, particularly studying the role of novel G-protein-coupled receptors in reproductive cells and other tissues.
  • Sperm biology.
  • Development of novel immunoassays for the measurement of hormones and signalling molecules in a variety of different matrices, mostly employing a time-resolved fluorescence immunoassay (TRFIA) platform.

Teaching Summary

I teach in the following UG and PG modules

Introductory Physiology (BIOS1001)

Reproductive Physiology (BIOS2011) (convenor)

Endocrinology Control Systems (BIOS2028) (convenor)

Reproduction and Fertility (D236Z5)

Academic Development and Employability skills (D21BP1)

Antibody Biotechnology (BIOS4004)

Research Summary

The role of the neohormones relaxin and INSL3, and their G-protein-coupled receptors, in male and female physiology. In the male this relates to foetal development, puberty, and healthy ageing; in… read more

Selected Publications

  • DAI Y, IVELL R, LIU X, JANOWSKI D and ANAND-IVELL R, 2017. Frontiers in physiology. 8, 359
  • TOFT, GUNNAR, JONSSON, BO A. G., BONDE, JENS PETER, NORGAARD-PEDERSEN, BENT, HOUGAARD, DAVID M., COHEN, ARIEH, LINDH, CHRISTIAN H., IVELL, RICHARD, ANAND-IVELL, RAVINDER and LINDHARD, MORTEN S., 2016. ENVIRONMENTAL HEALTH PERSPECTIVES. 124(1), 151-156
  • IVELL, RICHARD, DAI, YANZHENZI, MANN, NAVDEEP and ANAND-IVELL, RAVINDER, 2014. MOLECULAR AND CELLULAR ENDOCRINOLOGY. 382(1), 466-471
  • GLYNN DJ, HENG K, RUSSELL DL, SHARKEY DJ, ROBERTSON SA, ANAND-IVELL R and IVELL R, 2017. Frontiers in physiology. 8, 422

Current Research

  • The role of the neohormones relaxin and INSL3, and their G-protein-coupled receptors, in male and female physiology. In the male this relates to foetal development, puberty, and healthy ageing; in the female to fertility and miscarriage, as well as to ovarian dysfunction.
  • The role of foetal gender on maternal physiology.
  • Mechanisms of action of environmental endocrine disrupting chemicals, such as phthalates and xenoestrogens, in influencing the reproductive phenotype.
  • Non-classical actions of steroid hormones on reproductive cells and tissues.
  • Development of a new cell-based kidney model for evaluating excretion.
  • DAI Y, IVELL R, LIU X, JANOWSKI D and ANAND-IVELL R, 2017. Frontiers in physiology. 8, 359
  • GLYNN DJ, HENG K, RUSSELL DL, SHARKEY DJ, ROBERTSON SA, ANAND-IVELL R and IVELL R, 2017. Frontiers in physiology. 8, 422
  • TOFT, GUNNAR, JONSSON, BO A. G., BONDE, JENS PETER, NORGAARD-PEDERSEN, BENT, HOUGAARD, DAVID M., COHEN, ARIEH, LINDH, CHRISTIAN H., IVELL, RICHARD, ANAND-IVELL, RAVINDER and LINDHARD, MORTEN S., 2016. ENVIRONMENTAL HEALTH PERSPECTIVES. 124(1), 151-156
  • VERNUNFT, ANDREAS, IVELL, RICHARD, HENG, KEE and ANAND-IVELL, RAVINDER, 2016. PLOS ONE. 11(3),
  • IVELL R, AGOULNIK AI and ANAND-IVELL R, 2016. British journal of pharmacology. 174(10), 990-1001
  • VERNUNFT A, IVELL R, HENG K and ANAND-IVELL R, 2016. PloS one. 11(6), e0157954
  • HAGEN, CASPER P., MIERITZ, MIKKEL G., NIELSEN, JOHN E., ANAND-IVELL, RAVINDER, IVELL, RICHARD and JUUL, ANDERS, 2015. FERTILITY AND STERILITY. 103(3), 780-U502
  • JENSEN, MORTEN SONDERGAARD, ANAND-IVELL, RAVINDER, NORGAARD-PEDERSEN, BENT, JONSSON, BO A. G., BONDE, JENS PETER, HOUGAARD, DAVID M., COHEN, ARIEH, LINDH, CHRISTIAN H., IVELL, RICHARD and TOFT, GUNNAR, 2015. EPIDEMIOLOGY. 26(1), 91-99
  • BARTHOLD, JULIA S., ROBBINS, ALAN, WANG, YANPING, PUGARELLI, JOAN, MATESON, ABIGAIL, ANAND-IVELL, RAVINDER, IVELL, RICHARD, MCCAHAN, SUZANNE M. and AKINS, ROBERT E., JR., 2014. BIOLOGY OF REPRODUCTION. 91(2),
  • JOHANSEN, MARIE LINDHARDT, ANAND-IVELL, RAVINDER, MOURITSEN, ANNETTE, HAGEN, CASPER P., MIERITZ, MIKKEL G., SOEBORG, TUE, JOHANNSEN, TRINE HOLM, MAIN, KATHARINA M., ANDERSSON, ANNA-MARIA, IVELL, RICHARD and JUUL, ANDERS, 2014. REPRODUCTION. 147(4), 529-535
  • IVELL, RICHARD, DAI, YANZHENZI, MANN, NAVDEEP and ANAND-IVELL, RAVINDER, 2014. MOLECULAR AND CELLULAR ENDOCRINOLOGY. 382(1), 466-471
  • IVELL, RICHARD, HENG, KEE and ANAND-IVELL, RAVINDER, 2014. Frontiers in endocrinology. 5, 6
  • BARTHOLD, JULIA S, BARTHOLD, JULIA S, ROBBINS, ALAN, WANG, YANPING, PUGARELLI, JOAN, MATESON, ABIGAIL, ANAND-IVELL, RAVINDER, IVELL, RICHARD, MCCAHAN, SUZANNE M and AKINS , ROBERT E, JR, 2014. GSE57924: Cryptorchidism in the orl rat is associated with muscle patterning defects in the fetal gubernaculum and altered hormonal signaling Gene Expression Omnibus.
  • BAY K, ANAND-IVELL R, 2014.
  • ANAND-IVELL R and IVELL R, 2013. Molecular and cellular endocrinology. 382(1), 472-9
  • ANAND-IVELL R and IVELL R, 2013. Reproduction (Cambridge, England). 147(4), R87-95
  • IVELL R, HENG K, NICHOLSON H and ANAND-IVELL R, 2013. Asian journal of andrology. 15(2), 261-8
  • ANAND-IVELL R, DAI Y and IVELL R, 2013. Fertility and sterility. 99(4), 1153-60
  • GLISTER C, SATCHELL L, BATHGATE RA, WADE JD, DAI Y, IVELL R, ANAND-IVELL R, RODGERS RJ and KNIGHT PG, 2013. Proceedings of the National Academy of Sciences of the United States of America. 110(15), E1426-35
  • SATCHELL L, GLISTER C, BLEACH EC, GLENCROSS RG, BICKNELL AB, DAI Y, ANAND-IVELL R, IVELL R and KNIGHT PG, 2013. Endocrinology. 154(5), 1897-906
  • IVELL R, WADE JD and ANAND-IVELL R, 2013. Biology of reproduction. 88(6), 147
  • ANAND-IVELL R, TREMELLEN K, DAI Y, HENG K, YOSHIDA M, KNIGHT PG, HALE GE and IVELL R, 2013. Human reproduction (Oxford, England). 28(11), 3093-102
  • HUNTER D, ANAND-IVELL R, DANNER S and IVELL R, 2012. Spermatogenesis. 2(1), 32-43
  • JENSEN MS, N脴RGAARD-PEDERSEN B, TOFT G, HOUGAARD DM, BONDE JP, COHEN A, THULSTRUP AM, IVELL R, ANAND-IVELL R, LINDH CH and J脰NSSON BA, 2012. Environmental health perspectives. 120(6), 897-903
  • HENG K, ANAND-IVELL R, TEERDS K and IVELL R, 2011. International journal of andrology. 35(3), 353-63
  • ANAND-IVELL R and IVELL R, 2011. The Biochemical journal. 436(3), e3-5
  • ANAND-IVELL R, HIENDLEDER S, VI脩OLES C, MARTIN GB, FITZSIMMONS C, EURICH A, HAFEN B and IVELL R, 2011. PloS one. 6(5), e19821
  • IVELL R and ANAND-IVELL R, 2011. Current opinion in endocrinology, diabetes, and obesity. 18(3), 210-6
  • IVELL R, KOTULA-BALAK M, GLYNN D, HENG K and ANAND-IVELL R, 2010. Molecular human reproduction. 17(2), 71-84
  • ANAND-IVELL R, HENG K, HAFEN B, SETCHELL B and IVELL R, 2009. Biology of reproduction. 81(3), 480-7
  • IVELL R and ANAND-IVELL R, 2009. Human reproduction update. 15(4), 463-76
  • ATLANTIS E, MARTIN SA, HAREN MT, O'LOUGHLIN PD, TAYLOR AW, ANAND-IVELL R, IVELL R, WITTERT GA and , 2009. Clinical endocrinology. 71(2), 261-72
  • RIJNTJES E, SWARTS HJ, ANAND-IVELL R and TEERDS KJ, 2008. American journal of physiology. Endocrinology and metabolism. 296(2), E305-14
  • HENG K, IVELL R, WAGAARACHCHI P and ANAND-IVELL R, 2008. Molecular human reproduction. 14(10), 603-11
  • ANAND-IVELL R, IVELL R, DRISCOLL D and MANSON J, 2008. Human reproduction (Oxford, England). 23(5), 1180-6
  • IVELL R, HENG K and ANAND-IVELL R, 2007. Advances in experimental medicine and biology. 612, 26-33
  • ANAND-IVELL R, HENG K, BARTSCH O and IVELL R, 2007. Molecular and cellular endocrinology. 272(1-2), 1-13
  • ANAND-IVELL R, WOHLGEMUTH J, HAREN MT, HOPE PJ, HATZINIKOLAS G, WITTERT G and IVELL R, 2006. International journal of andrology. 29(6), 618-26
  • ANAND-IVELL RJ, RELAN V, BALVERS M, COIFFEC-DORVAL I, FRITSCH M, BATHGATE RA and IVELL R, 2006. Biology of reproduction. 74(5), 945-53
  • SADEGHIAN H, ANAND-IVELL R, BALVERS M, RELAN V and IVELL R, 2005. Molecular and cellular endocrinology. 241(1-2), 10-20
  • IVELL R, HARTUNG S and ANAND-IVELL R, 2005. Annals of the New York Academy of Sciences. 1041, 486-96
  • IVELL R, ANAND-IVELL R and BARTSCH O, 2005. Annals of the New York Academy of Sciences. 1041, 280-7
  • IVELL R, BALVERS M, ANAND RJ, PAUST HJ, MCKINNELL C and SHARPE R, 2003. Endocrinology. 144(7), 3130-7
  • ANAND RJ, PAUST HJ, ALTENPOHL K and MUKHOPADHYAY AK, 2003. Biology of reproduction. 68(5), 1663-73
  • ANAND RJ, KANWAR U and SANYAL SN, 1996. Ca(2+)-transport across brush border and basal surfaces of human term [correction of terms] placenta. Indian journal of experimental biology. 34(8), 786-93
  • ANAND RJ, KANWAR U and SANYAL SN, 1996. Isolation and characterization of the basal cell membranes of the human term placenta. Indian journal of biochemistry & biophysics. 33(4), 298-307
  • ANAND RJ, KANWAR U and SANYAL SN, 1996. Transport of glycine in the brush border and basal cell membrane vesicles of the human term placenta. Biochemistry and molecular biology international. 38(1), 21-30
  • ANAND RJ, KANWAR U and SANYAL SN, 1996. Placental membrane transport: leucine transport across the brush border and basal cell membrane surfaces. Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie. 196(1), 29-43
  • ANAND RJ, KANWAR U and SANYAL SN, 1994. Calcium channel antagonist verapamil modulates human spermatozoal functions. Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie. 194(3), 165-78
  • KANWAR U, ANAND RJ and SANYAL SN, 1993. The effect of nifedipine, a calcium channel blocker, on human spermatozoal functions. Contraception. 48(5), 453-70
  • In: Endocrinology of the Fetal Testis

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