糖心原创

School of Biosciences
 

Image of Graham Seymour

Graham Seymour

Emeritus Professor of Plant Biotechnology,

Contact

Research Summary

Research Interests: Genetic and Epigenetic Basis of Fruit Quality Traits

Fleshy fruits are economically highly valuable and provide a substantial part of the daily intake of vitamins and minerals whether they are consumed in a fresh or processed condition. They also contain important bioactives including a range of antioxidants. There is evidence emerging that the genes that regulate ripening have been conserved during the evolution of fruit bearing species. In my laboratory the aim is to understand the molecular circuits that are involved in controlling fruit ripening (Manning et al., 2006. Nature Genetics 38, 948 - 952; Seymour et al., 2008.Current Opinion in Plant Biology, 11: 58-62; The Tomato Genome Consortium 2012 Nature 485: 635-641; Seymour et al., 2013. Annual Review of Plant Biology, 64: 219-241. This mechanistic understanding is essential if step changes are to be made in the pace of crop improvement. Key targets are to enhance shelf-life and therefore reduce post-harvest waste, while enhancing flavour and levels of health promoting compounds. There are several strands to the research programme:

Tomato as a Model for Understanding Ripening - We use tomato as a model to study fruit ripening. This is because of the wealth of genetic and molecular resources available for this species and the extensive research effort that has been focused on understanding tomato fruit ripening over the last 40 years. The resources available include a fully annotated genome sequence which can be found at () and also a small number of single gene mutations exist. Tomato ripening is initiated and co-ordinated by ethylene, but there are also regulatory genes that act together with this plant hormone during the ripening process. A number of rare single gene mutations such as ripening-inhibitor (rin), non-ripening (nor) and Colourless non-ripening (Cnr) have pleiotropic effects resulting in the reduction or almost complete abolition of ripening. These mutants represent lesions in master switches controlling the ripening process which appear to act up-stream of ethylene. The molecular basis of the rin mutation was uncovered by positional cloning in 2002 (Vrebalov et al Science 296: 343-346). The RIN gene encodes a MADS-box transcription factor. MADS-box genes have commonly been associated with floral development or other major phase changes. However, their association with ripening is perhaps not that surprising as flowering plants are the only group to possess true fruits.

Ken Manning (then at Warwick University) and I used a genetic map-based approach to isolate the gene at the Cnr locus. This gene encodes a member of the SBP-box class of transcript factors and its gene product is likely to control the expression of specific MADS-box genes. Unexpectedly, Cnr was revealed to be an epigenetic mutation where expression of the CNR gene was silenced by elevated levels of methylation in the gene regulatory region (Manning et al., 2006. Nature Genetics 38, 948 - 952).

Since then several other master switches controlling the ripening process have been identified including the MADS-box genes TDR4 and TAGL1.Interestingly TDR4 and TAGL1 are similar to genes in the model plant Arabidopsis that control the development and dehiscence of its dry fruits, which are known botanically as siliques. We wanted to explore the possibility that many of the master switches found to control ripening in tomato have been conserved during the evolution of fruit bearing species. Together with Ken Manning at Warwick and Jim Giovannoni at Cornell we identified a gene in the same class of transcription factors as RIN that can modulate ripening in strawberry a non-climacteric fruit. Silencing a strawberry SEP1/2-like MADS gene results in slow ripening (Seymour et al 2011, Journal of Experimental Botany 62, 1179-1188.). Other ripening-related genes found in tomato also have homologs in other species. The function of the ripening expressed TDR4 gene in tomato is not known, but Laura Jaakola, then at the University of Oulu in Finland, and now at University of Troms酶, Norway, was able to isolate a TDR4-like gene from ripening bilberry fruits. These berries contain very high levels of anthocyanins that give the fruit their characteristic dark purple colour. We found that silencing the bilberry version of the MADS-box gene TDR4 dramatically altered anthocyanin accumulation in this fruit (Jaakola et al., 2010. Plant Physiology, 153: 1619-1629).

The Tomato Genome - from Genes to Quantitative Trait Loci (QTL) and Networks

I was involved with colleagues from Imperial, Hutton and TGAC in spearheadingthe UK contribution to the international programme to sequence the tomato genome with funding from BBSRC, Defra and SEERAD. The tomato genome sequence has now been published (The Tomato Genome Consortium 2012 Nature 485:635 - 641).It will underpin all future studies of natural variation across the tomato genome and help us better understand the genetic and molecular basis of fruit quality traits. In my lab we have used the sequence to identify genes under a complex QTL for fruit texture (Chapman et al., 2012, Plant Physiology 159, 1644-1657; Uluisik et al, Nature Biotechnology 2016 doi:10.1038/nbt.3602; Wang et al, 2019, Plant Physiology DOI: https://doi.org/10.1104/pp.18.01187) and in collaboration with Dr Philippe Gallusci at INRA we are exploring the role of natural epigenetic variation and its impact on fruit phenotypes (Liu et al, PNAS 112, 10804-10809, 2015).

.

Selected Publications

  • ULUISIK, S., CHAPMAN, N.H., SMITH, R., POOLE, M., ADAMS, G., GILLIS, R.B., BESONG, T.M.D., SHELDON, J., STIEGELMEYER, S., PEREZ, L., SAMSULRIZAL, N., WANG, D., FISK, I.D., YANG, N., BAXTER, C., RICKETT, D., FRAY, R., BLANCO-ULATE, B., POWELL, A.L.T., HARDING, S.E., CRAIGON, J., ROSE, J.K.C., FICH, E.A., SUN, L., DOMOZYCH, D.S., FRASER, P.D., TUCKER, G.A., GRIERSON, D. and SEYMOUR, G.B., 2016. Nature Biotechnology. 34(9), doi:10.1038/nbt.3602
  • LIU R, HOW-KIT A, STAMMITTIA L, TEYSSIERA E, ROLINA D, MORTAIN-BERTRANDA A, HALLEA S, LIUC M, KONGE J, WUE C, DEGRAEVE-GUIBAULTA C, CHAPMAN NH, MAUCOURTA M, HODGMAN TC, TOST J, BOUZAYEN M, HONG Y, SEYMOUR GB, GIOVANNONI JJ and GALLUSCI P, 2015. Proceedings of the National Academy of Sciences. 112(34), 10804-9
  • THE TOMATO GENOME CONSORTIUM, 2012. Nature. 485(7400), 635-641
  • MANNING, K., TOR, M., POOLE M., HONG, Y., THOMPSON, A.J., KING, G.J., GIOVANNONI, J.J. and SEYMOUR, G.B., 2006. Nature Genetics. 38(8), 948-952
  • WANG, RUFANG, ANGENENT, GERCO C., SEYMOUR, GRAHAM and DE MAAGD, RUUD A., 2020. TRENDS IN PLANT SCIENCE. 25(3), 291-301
  • WANG, DUODUO, SAMSULRIZAL, NURUL H., YANG, CHENG, ALLCOCK, NATALIE S., CRAIGON, JIM, BLANCO-ULATE, BARBARA, ORTEGA-SALAZAR, ISABEL, MARCUS, SUSAN E., BAGHERI, HASSAN MOEINIYAN, PEREZ-FONS, LAURA, FRASER, PAUL D., FOSTER, TIMOTHY, FRAY, RUPERT, KNOX, J. PAUL and SEYMOUR, GRAHAM B., 2019. PLANT PHYSIOLOGY. 179(2), 544-557
  • WANG, DUODUO, YEATS, TREVOR H., ULUISIK, SELMAN, ROSE, JOCELYN K. C. and SEYMOUR, GRAHAM B., 2018. TRENDS IN PLANT SCIENCE. 23(4), 302-310
  • WANG D, 2017. Molecular Plant. 10(6), 782-784
  • BARTON, N.A., MARSH, B.J., LEWIS, W., NARRAIDOO, N., SEYMOUR, G.B., FRAY, R.G. and HAYES, C.J., 2016. Chemical Science.
  • GALLUSCI, P., HODGMAN, T.C., TEYSSIER, E. and SEYMOUR, G.B., 2016. Frontiers in Plant Science. 7, 807
  • MUSTAFA, M.A., ALI, A. and SEYMOUR, G., 2016. Postharvest Biology and Technology. 118, 79-86
  • ULUISIK, S., CHAPMAN, N.H., SMITH, R., POOLE, M., ADAMS, G., GILLIS, R.B., BESONG, T.M.D., SHELDON, J., STIEGELMEYER, S., PEREZ, L., SAMSULRIZAL, N., WANG, D., FISK, I.D., YANG, N., BAXTER, C., RICKETT, D., FRAY, R., BLANCO-ULATE, B., POWELL, A.L.T., HARDING, S.E., CRAIGON, J., ROSE, J.K.C., FICH, E.A., SUN, L., DOMOZYCH, D.S., FRASER, P.D., TUCKER, G.A., GRIERSON, D. and SEYMOUR, G.B., 2016. Nature Biotechnology. 34(9), doi:10.1038/nbt.3602
  • CHEN, WEIWEI, KONG, JUNHUA, QIN, CHENG, YU, SHENG, TAN, JINJUAN, CHEN, YUN-RU, WU, CHAOQUN, WANG, HUI, SHI, YAN, LI, CHUNYANG, LI, BIN, ZHANG, PENGCHENG, WANG, YING, LAI, TONGFEI, YU, ZHIMING, ZHANG, XIAN, SHI, NONGNONG, WANG, HUIZHONG, OSMAN, TOBA, LIU, YULE, MANNING, KENNETH, JACKSON, STEPHEN, ROLIN, DOMINIQUE, ZHONG, SILIN, SEYMOUR, GRAHAM B., GALLUSCI, PHILIPPE and HONG, YIGUO, 2015. SCIENTIFIC REPORTS. 5,
  • MALEKPOOR MANSOORKHANI, F, SEYMOUR, G B, SWARUP, R, MOEINIYAN BAGHERI, H, RAMSEY, R J L and THOMPSON, A J, 2015. Biotechnology & genetic engineering reviews. 30(1-2), 95-112
  • LIU R, HOW-KIT A, STAMMITTIA L, TEYSSIERA E, ROLINA D, MORTAIN-BERTRANDA A, HALLEA S, LIUC M, KONGE J, WUE C, DEGRAEVE-GUIBAULTA C, CHAPMAN NH, MAUCOURTA M, HODGMAN TC, TOST J, BOUZAYEN M, HONG Y, SEYMOUR GB, GIOVANNONI JJ and GALLUSCI P, 2015. Proceedings of the National Academy of Sciences. 112(34), 10804-9
  • PAN Y, BRADLEY G, PYKE K, BALL G, LU C, FRAY R, MARSHAL A, AYASUTA S, BAXTER C, WIJK R V, BOYDEN L, CADE R, CHAPMAN NH, FRASER PD, HODGMAN C and SEYMOUR G, 2014. Plant Physiology. 161, 1476-1485
  • KARLOVA R, CHAPMAN N, DAVID K, ANGENENT GC, SEYMOUR GB and DE MAAGD RA, 2014. Journal of Experimental Botany. 65(16), 4527-4541
  • PEREZ-FONS, LAURA, WELLS, TOM, COROL, DELIA I., WARD, JANE L., GERRISH, CHRISTOPHER, BEALE, MICHAEL H., SEYMOUR, GRAHAM B., BRAMLEY, PETER M. and FRASER, PAUL D., 2014. SCIENTIFIC REPORTS. 4,
  • SEYMOUR GB, CHAPMAN NH, CHEW BL and ROSE JKC, 2013. Plant Biotechnology Journal. 11(3), 269-278
  • SEYMOUR, GRAHAM B, OSTERGAARD, LARS, CHAPMAN, NATALIE H, KNAPP, SANDRA and MARTIN, CATHIE, 2013. Annual Review of Plant Biology. 64, 219-41
  • PAN, Y., SEYMOUR, G.B., LU, C., HU, Z., CHEN, X. and CHEN, G., 2012. Plant Cell Reports. 31(2), 349-360
  • THE TOMATO GENOME CONSORTIUM, 2012. Nature. 485(7400), 635-641
  • CHAPMAN NH, BONNET J, GRIVET L, LYNN J, GRAHAM N, SMITH R, SUN G, WALLEY PG, POOLE M, CAUSSE M, KING GJ, BAXTER C and SEYMOUR GB, 2012. Plant physiology. 159, 1644-1657
  • LAHAYE M, QUEMENER B, CAUSSE M and SEYMOUR GB, 2012. International journal of biological macromolecules. 51(4), 462-70
  • SEYMOUR, G.B., RYDER, C.D., CEVIK, V., HAMMOND, J.P., POPOVICH, A., KING, G.J., VREBALOV, J., GIOVANNONI, J.J. and MANNING, K., 2011. Journal of Experimental Botany. 62(3), 1179-1188
  • VOLKAN CEVIK, CAROL D. RYDER, ALEXANDRA POPOVICH, KENNETH MANNING, GRAHAM J. KING and GRAHAM B. SEYMOUR, 2010. Tree Genetics and Genomes. 6, 271-279
  • JAAKOLA, L., POOLE,MM, JONES, M.O., K脛M脛R脛INEN-KARPPINEN, T., KOSKIM脛KI, J.J., HOHTOLA, A., H脛GGMAN, H., FRASER, P.D., MANNING, K., KING, G.J., THOMSON, H. and SEYMOUR GB, 2010. Plant Physiology. 153(4), 1619-29
  • FERNANDEZ, A.I., VIRON, N., ALHAGDOW, M., KARIMI, M., JONES, M., AMSELLEM, Z., SICARD, A., CZEREDNIK, A., ANGENENT, G., GRIERSON, D., MAY, S, SEYMOUR, G, ESHED, Y and LEMAIRE-CHAMLEY, ROTHAN, C. AND H, 2009. Plant Physiology. doi.10.1104/pp.109.147546
  • MUELLER, L.A., LANKHORST, R.K., TANKSLEY, S.D., GIOVANNONI, J.J., WHITE, R., VREBALOV, J., FEI, Z., VAN ECK, J., BUELS, R., MILLS, A.A., MENDA, N., TECLE, I.Y., BOMBARELY, A., STACK, S., ROYER, S.M. and SEYMOUR, G.B., 2009. Plant Genome. 2(1), 78-92
  • FABI, J.P., CORDENUNSI, B.R., SEYMOUR, G.B., LAJOLA, F.M. and DO NASCIMENTO, J.R.O., 2009. Plant Physiology and Biochemistry. 47, 1075-1081
  • VREBALOV, J., PAN, I.L., MATAS ARROYO, A.J., MCQUINN, R., CHUNG, M-Y., POOLE, M., ROSE, J., SEYMOUR, G., GRANDILLO, S., GIOVANNONI, J. and IRISH, V.F., 2009. Plant Cell. doi.10.1105/tpc.109.066936
  • KOVACS, KATALIN, FRAY, RUPERT G., TIKUNOV, YURY, GRAHAM, NEIL, BRADLEY, GLYN, SEYMOUR, GRAHAM B., BOVY, ARNAUD G. and GRIERSON, DONALD, 2009. PHYTOCHEMISTRY. 70(8), 1003-1008
  • SEYMOUR G, POOLE M, MANNING K and KING GJ, 2008. Current Opinion In Plant Biology. 11(1), 58-63
  • PILCHER, R.L, MOXON, S., PAKSERESHT, N., MOULTON, V., MANNING, K. and SEYMOUR, G. AND DALMAY, T., 2007. Planta. 226, 709-717
  • MANNING, K., TOR, M., POOLE M., HONG, Y., THOMPSON, A.J., KING, G.J., GIOVANNONI, J.J. and SEYMOUR, G.B., 2006. Nature Genetics. 38(8), 948-952
  • BARRY, C.S., MCQUINN, R.P., THOMPSON, A.J., SEYMOUR, G.B., GRIERSON, D. and GIOVANNONI, J.J., 2005. Plant Physiology. VOL 138(NUMB 1), 267-275
  • MUELLER, L.A, TANKSLEY, S.D, GIOVANNONI J.J, VAN ECK J, STACK, S, CHOI, D, KIM, BD, CHEN, M.S, CHENG ZK, LI, C.Y, LING, H.Q, XUE, Y.B, SEYMOUR, G.B, BISHOP, G, BRYAN, SHARMA, R and KHURANA J., 2005. Comparative and Functional Genomics. 6, 153-158
  • SEYMOUR, G.B. AND BISHOP, G., 2005. Breeding better varieties through the tomato genome sequencing programme. The Grower. 18-19
  • ERIKSSON, E.M., BOVY, A., MANNING, K., HARRISON, L., ANDREWS, J., DE SILVA, J., TUCKER, G.A. and SEYMOUR, G.B., 2004. Plant Physiology. 136(4), 4184-4307
  • MARIN, C., SMITH, D., MANNING, K., ORCHARD, J. and SEYMOUR, G.B., 2003. Plant Molecular Biology. 51(6), 851-7
  • SEYMOUR, G.B and MANNING, K. AND KING, G.J., 2003. A New Frontier in Fruit Ripening Research. The Grower. 14-15
  • SEYMOUR, G.B and DODDS, C. AND TUCKER, G.A., 2003. Cell adhesion in plant, microbial and animal systems. Biotechnology & Genetic Engineering Reviews. 21, 123-130
  • TUCKER, GREG and SEYMOUR, GRAHAM, 2002. Nature Biotechnology. 20(6), 558-60
  • SEYMOUR, G. B., MANNING, K., ERIKSSON, E. M., POPOVICH, A. H. and KING, G. J., 2002. Journal of Experimental Botany. VOL 53(ISSU 377), 2065-2072
  • MARIN-RODRIGUEZ, M. C., ORCHARD, J. and SEYMOUR, G. B., 2002. Journal of Experimental Botany. VOL 53(ISSU 377), 2115-2120
  • ORFILA, C., HUISMAN, M. M., WILLATS, W. G., VAN ALEBEEK, G.-J. W., SCHOLS, H. A., SEYMOUR, G. B. and KNOX, J. P., 2002. Planta. VOL 215(PART 3), 440-447
  • KNOX, J. P. (J. PAUL) and SEYMOUR, G. B. (GRAHAM B.), 2002. Pectins and their manipulation: edited by Graham B. Seymour and J. Paul Knox Oxford : Blackwell, 2002.
  • SEYMOUR, G.B., MANNING, K., ERIKSSON, E.M and POPOVICH A.H. AND KING, GJ, 2002. Journal of Experimental Botany. 53, 2065-2071
  • TOR, M, MANNING, K, KING, G.J, THOMPSON, A.J, JONES, G.H and SEYMOUR, G.B. AND ARMSTRONG, S. J., 2002. Genetic analysis and FISH mapping of the Colourless non-ripening locus of tomato. Theoretical and Applied Genetics. 40, 165-170
  • SEYMOUR G.B. AND TUCKER, G.A., 2002. Modification and degradation of pectins.. In: G.B. SEYMOUR & J.P. KNOX, ed., Pectins and their Manipulation Blackwell Publishing. 250 (In Press.)
  • CAREY, A.T., SMITH, D.L., HARRISON, E., BIRD, C.R., GROSS, K.C., SEYMOUR, G.B. and TUCKER, G.A., 2001. Down-regulation of a ripening-related 尾-galactosidase gene (TBG1) in transgenic tomato fruits Journal of Experimental Botany. 52(357), 663-668
  • ORFILA, C., SEYMOUR, G.B., WILLATS, W.G.T., HUXHAM, I.M., JARVIS, M.C., DOVER, C.J., THOMPSON, A.J. and KNOX, J.P., 2001. Plant Physiology. 126(1), 210-221
  • SEYMOUR, G. B. AND MANNING, K., 2001. In: M. KNEE, ed., Fruit quality and its biological basis Sheffield Academic Press. 277
  • KING, G. J., LYNN, J. R., DOVER, C. J., EVANS, K. M. and SEYMOUR, G. B., 2001. Theoretical and Applied Genetics. VOL 102(PART 8), 1227-1235
  • JOHNSON, D. S, SEYMOUR, G. B, DOVER, C. J and SAMUELSON, T. J. & SHAKESPEARE, L., 2001. Investigation of textural quality development and post-harvest softening in Cox's Orange Pippin apples In: Innovative Approaches to Improving Food Quality. 1
  • SEYMOUR, G. B, TOR, M, MANNING, K, KING, G. J, THOMPSON, A. J and ARMSTRONG, S. J. & JONES, G. H., 2001. FISH mapping on meiotic pachytene chromosome of tomato localises the Cnr gene to the euchromatin of the long arm of chromosome 2 In: Plant & Animal Genome IX Conference.
  • JOHNSON, D, DOVER, C, SAMUELSON,T, HUXHAM, I.M, JARVIS, M.C and SHAKESPEARE, L. AND SEYMOUR, G.B., 2001. Nitrogen, cell walls and texture of stored Cox's Orange Pippin Apples Acta Horticulture. 564, 105-112
  • FRASER, P D, BRAMLEY, P and SEYMOUR, G B, 2001. Phytochemistry. 58(1), 75-9
  • JOHNSON, D. S, SEYMOUR, G. B, DOVER, C. J and SAMUELSON, T. J. & SHAKESPEARE, L., 2001. Investigation of textural quality development and post-harvest softening in Cox's Orange Pippin apples In: Innovative Approaches to Improving Food Quality. 1
  • THOMPSON, A.J., BARRY, C.S., JARVIS, M.C., GIOVANNONI, J.J., GRIERSON, D and SEYMOUR, G.B., 1999. Plant Physiology. 120(2), 383-90
  • BIRD, C. R, FRAY, R. G, GRIERSON, D, SCHUCH, W and SEYMOUR, G. B. & TUCKER, G. A., 1999. Co-ordinated inhibition of plant gene expression US Patent No. US5942 01/01/1900 00:00:00
  • DRURY, R., HOERTENSTEINER, S., DONNISON, I., BIRD, C. R. and SEYMOUR, G. B., 1999. Physiologia Plantarum. VOL 107(NUMBER 1), 32-38
  • JOHNSON, D, DOVER, C and SEYMOUR, G.B. AND SHAKESPEARE, L, 1999. Investigation of textural quality development and postharvest softening in Cox's orange pippin apples APRC News. 22, 6-8
  • BIRD, C. R, HOLT, K. A, PICARD, S, SCHUCH, W, CAREY, A. T and SEYMOUR, G. B. & TUCKER, G. A., 1999. Modified fruit containing galactanase transgene. US Patent No. US5859 01/01/1900 00:00:00
  • MEDINA-SUAREZ, R, MANNING, K, FLETCHER, J, AKED, J and BIRD, C. R. & SEYMOUR, G. B., 1999. Musa acuminata mRNA; 46 Sequences EMBL/GenBank/DDBJ databases.
  • HUXHAM, I. M., JARVIS, M. C., SHAKESPEARE, L., DOVER, C. J., JOHNSON, D., KNOX, J. P. and SEYMOUR, G. B., 1999. Planta. VOL 208(NUMBER 3), 438-443
  • DRURY, R and BIRD, C.R. AND SEYMOUR, G.B., 1998. In: K.E. COCKSHULL, D.GRAY, G.B.SEYMOUR AND B. THOMAS., ed., Genetic and Environmental Manipulation of Horticultural Crops. CAB International, Oxford. 41-49
  • COCKSHULL, K.E, GRAY, D and SEYMOUR, G.B. AND THOMAS, eds., 1998. Genetic and Environmental Manipulation of Horticultural Crops. CAB International, Oxford.
  • BIRD, C. R and MEDINA-SUAREZ, R. & SEYMOUR, G. B., 1998. Genetic control of fruit ripening World Patent Applica 01/01/1900 00:00:00
  • SEYMOUR, G. B. & THOMPSON, A. J., 1997. Potential of molecular biology for manipulating tomato fruit ripening In: HDC/HRA/HRI Tomato Conference. 14
  • MEDINA-SUAREZ, R, MANNING, K, FLETCHER, J, AKED, J and BIRD, C. R. & SEYMOUR, G. B., 1997. Musa acuminata mRNA; 46 Sequences EMBL/GenBank/DDBJ databases.
  • MEDINA-SUAREZ, R., MANNING, K., FLETCHER, J., AKED, J., BIRD, C. R. and SEYMOUR, G. B., 1997. Plant Physiology. VOL 115(NUMBER 2), 453-461
  • JONES, L.J and SEYMOUR, G.B. AND KNOX, J.P., 1997. Characterisation of a monoclonal antibody probe to pectic beta-1,4-galactans and immunolocalisation in tomato cell walls. Plant Physiology. 113, 1405-1412
  • SEYMOUR, G.B. AND GROSS, K.C., 1996. Cell wall disassembly and fruit softening. Postharvest News and Information. 7, 45N-52N
  • MUDA, P., SEYMOUR, G. B., ERRINGTON, N. and TUCKER, G. A., 1995. Carbohydrate Polymers. VOL 26(NUMBER 4), 255
  • CAREY, A T, HOLT, K, PICARD, S, WILDE, R, TUCKER, G A, BIRD, C R, SCHUCH, W and SEYMOUR, G B, 1995. Plant Physiology. 108(3), 1099-107
  • CAREY, A. T, HOLT, K, PICARD, S, WILDE, R, TUCKER, G. A, BIRD, C. R and SCHUCH, W. AND SEYMOUR, G. B., 1995. Lycopersicon esculentum beta-alactosidase/galactanase protein (putative) EMBL/GenBank/DDBJ databases, Accession no. X83854.
  • FENWICK, K.M, JARVIS, M.C, APPERLEY, D.C and SEYMOUR, G.B. AND BIRD, C.R., 1995. Phytochemistry. 42, 301-307
  • HALL, L.N., BIRD, C.R., PICTON, S., TUCKER, G.A., SEYMOUR, G.B. and GRIERSON, D., 1994. Plant Molecular Biology. 25, 313-318
  • SEYMOUR, G. B., FRAY, R. G., HILL, P. and TUCKER, G. A., 1993. Plant Molecular Biology. VOL 23(NUMBER 1), 1
  • HALL, L.N, TUCKER, G.A, SMITH, C.J.S, WATSON, C.F, SEYMOUR, G.B, BUNDICK, Y, BONIWELL, J.M, FLETCHER, J.D, RAY, J.A, SCHUCH, W and BIRD, C.R. AND GRIERSON, D., 1993. The Plant Journal. 3, 121-129
  • SEYMOUR, G. B and EDWARDS, R. & HOBSON, G. E. (1993)., 1993. The chelator EDTA overcomes a genetic block to tomato fruit ripening Journal of the Science of Food and Agriculture. 131-132
  • SEYMOUR, G.B., 1993. In: G.B. SEYMOUR, J.E. TAYLOR AND G.A. TUCKER, ed., Biochemistry of Fruit Ripening. Chapman and Hall, London, New York. 83-106
  • SEYMOUR, G.B. AND MCGLASSON, W.B., 1993. In: G.B. SEYMOUR, J. E. TAYLOR AND G.A. TUCKER, ed., Biochemistry of Fruit Ripening. Chapman and Hall, London, New York. 274-290
  • SEYMOUR, G.B. AND TUCKER, G.A., 1993. Avocado. In: G.B. SEYMOUR, J.E. TAYLOR AND G.A. TUCKER, ed., Biochemistry of Fruit Ripening. Chapman and Hall. 53-81
  • SEYMOUR, G. B. (GRAHAM B.), TAYLOR, J. E. (JANE E.) and TUCKER, G. A. (GREGORY A.), 1993. Biochemistry of fruit ripening: edited by G. B. Seymour, J. E. Taylor, and G. A. Tucker Chapman & Hall, 1993.
  • TUCKER, G.A, SEYMOUR, G.B, LASSLETT, Y, ROBERTSON, D, HALL, L, SMITH, C.J.S, BIRD, C.R and SCHUCH, W. AND GRIERSON, D., 1992. Use of antisense RNA technology to study pectin degradation in tomato fruit. New Zealand Journal of Crop and Horticultural Science. 20, 119-124
  • TUCKER, G. A. & SEYMOUR, G. B., 1992. Cell wall degradation during ripening of mango fruit Acta Horticulturae. 291, 454-460
  • POGSON, B.J, SEYMOUR, G. B, BRADY, C.J and JONES, M. AND GOODCHILD, D., 1992. Immunolocalisation of pectinases in tomato fruit. New Zealand Journal of Crop and Horticultural Science. 20, 137-146
  • SEYMOUR, G.B and WAINWRIGHT, H. AND TUCKER, G.A., 1991. Cell wall changes in ripening fruit Acta Horticulturae. 269, 249-255
  • SMITH, N.J, SEYMOUR, G.B and TUCKER, G.A. AND JEGER, M., 1990. Cell wall changes in bananas and plantains Acta Horticulturae. 269, 283-289
  • GRIERSON, D, SMITH, C.J.S, WATSON, C.F, MORRIS, P, GRAY, J.E, DAVIES, PICTON, S.J, TUCKER, G.A, SEYMOUR, G.B, SCHUCH, W and BIRD, C.R. AND RAY, J., 1990. In: G.W. LYCELT AND D. GRIERSON, ed., Genetic Engineering of Crop Plants Butterworths, London.
  • SEYMOUR, G.B, COLQUHOUN, I.J, DUPONT, S and PARSLEY, K.R. AND SELVENDRAN, R., 1990. Phytochemistry. 29, 725-731
  • SEYMOUR, G.B and N'DIAYE, M. AND WAINWRIGHT, H., 1990. Effects of cultivar and harvest maturity on ripening of mangoes during storage. Journal of Horticultural Science. 65, 479-483
  • SMITH, N. J, SEYMOUR, G. B and TUCKER, G. A. & JEGER, M., 1990. Cell wall changes in bananas and plantains Acta horticulturae. 269, 283-289
  • SCHUCH, W., BIRD, C.R., RAY, J., SMITH, C.J., WATSON, C.F., MORRIS, P.C., GRAY, J.E., ARNOLD, C., SEYMOUR, G.B., TUCKER, G.A. and GRIERSON, D., 1989. Plant Molecular Biology. 13, 303-311
  • SMITH, C.J.S, WATSON, C.F, MORRIS P.C, BIRD, C.R, SEYMOUR, G.B, GRAY, J.E, HARDING, S.E, TUCKER, G.A and SCHUCH, W. AND GRIERSON, D., 1989. Plant Molecular Biology. 14, 369-379
  • SEYMOUR, G.B and WAINWRIGHT, H. AND TUCKER, G.A., 1989. Cell wall changes in ripening mangoes. Aspects of Applied Biology. 20, 93-94
  • SMITH, R and SEYMOUR, G.B. AND TUCKER, G.A., 1989. Inhibition of cell wall degradation by silver (I) ions during ripening of tomato fruit. Journal of Plant Physiology. 13, 514-516
  • SY, O and WAINWRIGHT, H. AND SEYMOUR, G.B., 1989. Post-harvest handling of mangoes, a case study from Senegal Aspects of Applied Biology. 20, 95-96
  • SEYMOUR, G.B and THOMPSON, A.K. AND JOHN, P., 1987. Annals of Applied Biology. 110, 145-151
  • SEYMOUR, G.B and LASSLETT, Y. AND TUCKER, G.A., 1987. Phytochemistry. 26, 3137-3139
  • SEYMOUR, G.B, HARDING, S.E, TAYLOR, A.J and HOBSON, G.E. AND TUCKER, G.A., 1987. Phytochemistry. 26, 1971-1975
  • SEYMOUR, G.B and JOHN, P. AND THOMPSON, A.K., 1987. Annals of Applied Biology. 110, 153-161
  • SEYMOUR, G.B. AND HARDING, S.E., 1987. Analysis of the molecular size of tomato fruit polyuronides by gel filtration and low sped sedimentation equilibrium. Biochemical Journal. 245, 463-466
  • SMITH, N.J.S and SEYMOUR, G.B. AND THOMPSON, A.K., 1985. Annals of Applied Biology. 108, 667-672
  • THOMPSON, A.K. AND SEYMOUR, G.B., 1982. Comparative effects of acetylene and ethylene gas on initiation of banana ripening. Annals of Applied Biology. 101, 407-410
  • HUTCHINSON, C.S. AND SEYMOUR, G.B., 1982. Biological flora of the British Isles, Poa annua L. Journal of Ecology. 70, 887-901
  • HUGHES, P.A, THOMPSON, A.K and PLUMBLEY, R.A. AND SEYMOUR, G.B., 1981. Storage of capsicums (Capsicum annuum L. (Sendt)) under controlled atmosphere, modified atmosphere and hypobaric conditions. Journal of Horticultural Science. 56(3), 261-265
  • SEYMOUR, G.B, THOMPSON, A.K and HUGHES, P.A. AND PLUMBLEY, R.A., 1980. The influence of hydrocooling and plastic box liners on the market quality of capsicums (Capsicum annuum) Acta Horticulturae. 116, 191-196

School of Biosciences

糖心原创
Sutton Bonington Campus
Nr Loughborough
LE12 5RD, UK

For all enquiries please visit:
www.nottingham.ac.uk/enquire

Find us
Campus map
Room Locations on Campus [pdf file]